MX2011007458A - Nuevo conjugado estable de polietilenglicol con interferon alfa, representado por un isomero posicional. - Google Patents
Nuevo conjugado estable de polietilenglicol con interferon alfa, representado por un isomero posicional.Info
- Publication number
- MX2011007458A MX2011007458A MX2011007458A MX2011007458A MX2011007458A MX 2011007458 A MX2011007458 A MX 2011007458A MX 2011007458 A MX2011007458 A MX 2011007458A MX 2011007458 A MX2011007458 A MX 2011007458A MX 2011007458 A MX2011007458 A MX 2011007458A
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Classifications
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/56—IFN-alpha
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
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- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
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- A61P31/12—Antivirals
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- A61P35/02—Antineoplastic agents specific for leukemia
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- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
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- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
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- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2010129824/10A RU2447083C1 (ru) | 2010-07-20 | 2010-07-20 | НОВЫЙ ФУНКЦИОНАЛЬНО АКТИВНЫЙ ВЫСОКООЧИЩЕННЫЙ СТАБИЛЬНЫЙ КОНЪЮГАТ ИНТЕРФЕРОНА α С ПОЛИЭТИЛЕНГЛИКОЛЕМ, ПРЕДСТАВЛЕННЫЙ ОДНИМ ПОЗИЦИОННЫМ ИЗОМЕРОМ ПЭГ-NαH-ИФН, С УМЕНЬШЕННОЙ ИММУНОГЕННОСТЬЮ, С ПРОЛОНГИРОВАННЫМ БИОЛОГИЧЕСКИМ ДЕЙСТВИЕМ, ПРИГОДНЫЙ ДЛЯ МЕДИЦИНСКОГО ПРИМЕНЕНИЯ, И ИММУНОБИОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ |
Publications (1)
| Publication Number | Publication Date |
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| MX2011007458A true MX2011007458A (es) | 2012-01-19 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| MX2011007458A MX2011007458A (es) | 2010-07-20 | 2011-07-12 | Nuevo conjugado estable de polietilenglicol con interferon alfa, representado por un isomero posicional. |
Country Status (20)
| Country | Link |
|---|---|
| KR (1) | KR101586372B1 (pt) |
| CN (1) | CN102617736B (pt) |
| AR (1) | AR087227A1 (pt) |
| BR (1) | BRPI1101565A2 (pt) |
| CO (1) | CO6680611A2 (pt) |
| CR (1) | CR20130021A (pt) |
| CU (1) | CU24193B1 (pt) |
| DO (1) | DOP2013000002A (pt) |
| EA (1) | EA020257B1 (pt) |
| EC (1) | ECSP13012398A (pt) |
| MX (1) | MX2011007458A (pt) |
| MY (1) | MY168784A (pt) |
| NI (1) | NI201300008A (pt) |
| PE (1) | PE20131034A1 (pt) |
| PH (1) | PH12012502425A1 (pt) |
| RU (1) | RU2447083C1 (pt) |
| SG (1) | SG187117A1 (pt) |
| UA (1) | UA99766C2 (pt) |
| UY (1) | UY33525A (pt) |
| WO (1) | WO2012011836A1 (pt) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| RU2515913C1 (ru) * | 2013-03-22 | 2014-05-20 | Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов" (ФГУП "ГосНИИгенетика") | ГИБРИДНЫЙ БЕЛОК, ОБЛАДАЮЩИЙ ПРОЛОНГИРОВАННЫМ ДЕЙСТВИЕМ, НА ОСНОВЕ РЕКОМБИНАНТНОГО ИНТЕРФЕРОНА АЛЬФА-2 ЧЕЛОВЕКА (ВАРИАНТЫ), СПОСОБ ЕГО ПОЛУЧЕНИЯ И ШТАММ Saccharomyces cerevisiae ДЛЯ ОСУЩЕСТВЛЕНИЯ ЭТОГО СПОСОБА (ВАРИАНТЫ) |
| EA021610B1 (ru) * | 2013-03-28 | 2015-07-30 | Илья Александрович МАРКОВ | Жидкое противовирусное лекарственное средство |
| EA021643B1 (ru) * | 2013-03-28 | 2015-07-30 | Илья Александрович МАРКОВ | Монопегилированный интерферон-альфа линейной структуры и фармацевтическая композиция для приготовления лекарственного средства, обладающего активностью интерферона-альфа |
| CN103463623B (zh) * | 2013-09-03 | 2015-09-09 | 长春海伯尔生物技术有限责任公司 | 一种聚乙二醇干扰素注射液及其制备方法 |
| RU2554761C1 (ru) * | 2014-05-13 | 2015-06-27 | Закрытое акционерное общество "Сибирский центр фармакологии и биотехнологии" | Противоэнтеровирусное и иммуностимулирующее средство |
| RU2572800C1 (ru) * | 2014-09-22 | 2016-01-20 | Закрытое Акционерное Общество "Биокад" | Новый состав, содержащий конъюгат пэг и интерферон-альфа-2бета, обладающий сниженной болезненностью при введении |
| EA029498B1 (ru) * | 2015-11-24 | 2018-04-30 | Учреждение Белорусского государственного университета "Научно-исследовательский институт физико-химических проблем" (НИИ ФХП БГУ) | ПРОТИВООПУХОЛЕВОЕ СРЕДСТВО НА ОСНОВЕ РЕКОМБИНАНТНОГО ИНТЕРФЕРОНА АЛЬФА-2b В ВИДЕ МИКРОЧАСТИЦ ДЛЯ ПАРЕНТЕРАЛЬНОГО ПРИМЕНЕНИЯ |
| RU2678332C1 (ru) | 2017-09-08 | 2019-01-28 | Общество с ограниченной ответственностью "Саентифик Фьючер Менеджмент" (ООО "СФМ") | Пегилированный интерферон лямбда, обладающий высокой биодоступностью при пероральном применении, и способ его получения |
| CA3184298A1 (en) * | 2020-04-20 | 2021-10-28 | Altum Pharmaceuticals Inc. | Recombinant interferon |
| CN114392237B (zh) * | 2021-12-28 | 2024-02-02 | 上海允英生物医药科技有限公司 | 一种冻干病毒制剂及其制备方法 |
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|---|---|---|---|---|
| US5951974A (en) * | 1993-11-10 | 1999-09-14 | Enzon, Inc. | Interferon polymer conjugates |
| US20030053982A1 (en) * | 1994-09-26 | 2003-03-20 | Kinstler Olaf B. | N-terminally chemically modified protein compositions and methods |
| TW426523B (en) * | 1995-04-06 | 2001-03-21 | Hoffmann La Roche | Interferon solution |
| TW517067B (en) * | 1996-05-31 | 2003-01-11 | Hoffmann La Roche | Interferon conjugates |
| ES2897470T3 (es) * | 2002-09-09 | 2022-03-01 | Nektar Therapeutics | Alcanales poliméricos solubles en agua |
| RU2311930C2 (ru) * | 2004-04-30 | 2007-12-10 | Закрытое акционерное общество "ВЕРОФАРМ" | Пэгилированный интерферон для борьбы с вирусной инфекцией |
| CA2572751A1 (en) * | 2004-06-30 | 2006-01-12 | Egen Corporation | Pegylated interferon alpha-1b |
| EP1915412B1 (en) * | 2005-07-19 | 2010-03-24 | Nektar Therapeutics | Method for preparing polymer maleimides |
| JP2009541333A (ja) * | 2006-06-23 | 2009-11-26 | クインテセンス バイオサイエンシーズ インコーポレーティッド | 修飾リボヌクレアーゼ |
| CN101491682A (zh) * | 2008-04-30 | 2009-07-29 | 北京凯正生物工程发展有限责任公司 | 聚乙二醇化重组人干扰素ω偶合物及其制备工艺 |
| CN101591387A (zh) * | 2008-05-28 | 2009-12-02 | 中国人民解放军军事医学科学院微生物流行病研究所 | 聚乙二醇化重组人干扰素ω偶合物 |
| CN101514229B (zh) * | 2009-04-03 | 2012-05-09 | 海南四环心脑血管药物研究院有限公司 | 人干扰素α衍生物及其聚乙二醇化修饰物 |
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| PE20131034A1 (es) | 2013-09-27 |
| DOP2013000002A (es) | 2013-09-15 |
| KR101586372B1 (ko) | 2016-01-18 |
| CN102617736A (zh) | 2012-08-01 |
| PH12012502425A1 (en) | 2013-07-08 |
| WO2012011836A1 (en) | 2012-01-26 |
| RU2010129824A (ru) | 2012-01-27 |
| NI201300008A (es) | 2014-05-26 |
| CR20130021A (es) | 2013-02-20 |
| CU20130013A7 (es) | 2013-04-19 |
| AR087227A1 (es) | 2014-03-12 |
| UA99766C2 (uk) | 2012-09-25 |
| EA020257B1 (ru) | 2014-09-30 |
| HK1170504A1 (zh) | 2013-03-01 |
| ECSP13012398A (es) | 2013-05-31 |
| CU24193B1 (es) | 2016-09-30 |
| MY168784A (en) | 2018-12-04 |
| BRPI1101565A2 (pt) | 2012-12-04 |
| EA201100809A1 (ru) | 2012-01-30 |
| KR20130056885A (ko) | 2013-05-30 |
| SG187117A1 (en) | 2013-02-28 |
| UY33525A (es) | 2012-02-29 |
| CN102617736B (zh) | 2015-11-25 |
| RU2447083C1 (ru) | 2012-04-10 |
| CO6680611A2 (es) | 2013-05-31 |
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