MX2010013759A - Conjugados para la administracion de compuestos biologicamente activos. - Google Patents
Conjugados para la administracion de compuestos biologicamente activos.Info
- Publication number
- MX2010013759A MX2010013759A MX2010013759A MX2010013759A MX2010013759A MX 2010013759 A MX2010013759 A MX 2010013759A MX 2010013759 A MX2010013759 A MX 2010013759A MX 2010013759 A MX2010013759 A MX 2010013759A MX 2010013759 A MX2010013759 A MX 2010013759A
- Authority
- MX
- Mexico
- Prior art keywords
- ifn
- apo
- peptide
- conjugate
- polynucleotide
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/5434—IL-12
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/56—IFN-alpha
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/775—Apolipopeptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Virology (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Communicable Diseases (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Marine Sciences & Fisheries (AREA)
- Dermatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Psychology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200801796 | 2008-06-13 | ||
| PCT/ES2009/070224 WO2009150284A2 (es) | 2008-06-13 | 2009-06-12 | Conjugados de apo-a para la administración de compuestos biológicamente activos |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2010013759A true MX2010013759A (es) | 2011-05-25 |
Family
ID=41338617
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2010013759A MX2010013759A (es) | 2008-06-13 | 2009-06-12 | Conjugados para la administracion de compuestos biologicamente activos. |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20110293557A1 (enExample) |
| EP (1) | EP2305309A2 (enExample) |
| JP (2) | JP5685529B2 (enExample) |
| CN (1) | CN102123737B (enExample) |
| AU (1) | AU2009256547B2 (enExample) |
| BR (1) | BRPI0915093A2 (enExample) |
| CA (1) | CA2727811A1 (enExample) |
| MX (1) | MX2010013759A (enExample) |
| RU (1) | RU2567667C2 (enExample) |
| WO (1) | WO2009150284A2 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2347627B1 (es) * | 2009-03-06 | 2011-10-10 | Isdin, S.A. | Peptido para el tratamiento profilactico o terapeutico de tumores de la piel en estadios iniciales. |
| AU2010329805B2 (en) | 2009-12-11 | 2016-07-14 | Proyecto De Biomedicina Cima S.L. | New conjugates and compositions for immunotherapy and anti-tumoral treatment |
| WO2011098644A2 (es) | 2010-02-09 | 2011-08-18 | Proyecto De Biomedicina Cima, S.L. | Composiciones para el tratamiento de enfermedades infecciosas y tumorales |
| CA2802388A1 (en) * | 2010-06-15 | 2011-12-22 | The Cleveland Clinic Foundation | Compositions and methods for treating cancer |
| SI2767546T1 (sl) | 2011-02-07 | 2019-03-29 | Cerenis Therapeutics Holding Sa | Lipoproteinski kompleksi in izdelava ter uporaba le-teh |
| JP2014132832A (ja) * | 2011-05-10 | 2014-07-24 | Sekisui Chem Co Ltd | 医薬、機能性食品、目的蛋白質の安定化方法、融合蛋白質、核酸、並びに、組換え体 |
| KR20140054115A (ko) * | 2011-08-25 | 2014-05-08 | 에프. 호프만-라 로슈 아게 | 단축 테트라넥틴-아포지단백질 a-i 융합 단백질, 그를 함유하는 지질 입자 및 그의 용도 |
| CN103073646A (zh) * | 2012-03-13 | 2013-05-01 | 华中科技大学 | 一种运载蜂毒肽的多肽、运载蜂毒肽的纳米颗粒及其应用 |
| ES2427854B1 (es) * | 2012-03-29 | 2014-09-15 | Universidad De Valladolid | Sensores de calcio y métodos para la detección de calcio libre intracelular |
| EP2735874A1 (en) | 2012-11-21 | 2014-05-28 | Fundación Para La Investigación Biomédica Del Hospital Universitario Puerta De Hierro | Methods of diagnosing and therapeutic agents for use in the treatment of prostate cancer |
| WO2014194362A1 (en) * | 2013-06-05 | 2014-12-11 | Csl Limited | Process for preparing apolipoprotein a-i (apo a-i) |
| KR101656929B1 (ko) * | 2014-06-02 | 2016-09-13 | 씨제이제일제당 (주) | 반추동물의 메탄 생성 저감용 사료 첨가제 조성물 |
| GB201410507D0 (en) * | 2014-06-12 | 2014-07-30 | Univ Bath | Drug delivery enhancement agents |
| DK3328881T3 (da) * | 2015-09-08 | 2019-10-07 | Theripion Inc | Apoa-1 fusionspolypeptider og relaterede sammensætninger og fremgangsmåder |
| US11390854B2 (en) | 2017-05-09 | 2022-07-19 | Fundacion Para La Investigacion Medica Aplicada | Human porphobilinogen deaminase derived proteins and polynucleotides and uses thereof |
| EP3950708A4 (en) * | 2019-04-05 | 2022-06-08 | Korea Institute of Ceramic Engineering and Technology | METHODS OF EXPRESSION AND PURIFICATION OF PROTEIN USING CSQ-TAG |
| CN110483648A (zh) * | 2019-08-27 | 2019-11-22 | 南京安吉生物科技有限公司 | 一种融合多肽及其应用 |
| FR3100715B1 (fr) * | 2019-09-12 | 2023-09-29 | Francais Du Sang Ets | Utilisation de HDL dans la prophylaxie de la maladie du greffon contre l’hôte |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1987002061A1 (en) * | 1985-10-03 | 1987-04-09 | Biotechnology Research Partners, Ltd. | Novel lipoprotein-based drug-delivery systems |
| WO1987002062A1 (en) | 1985-10-04 | 1987-04-09 | Biotechnology Research Partners, Ltd. | Recombinant apolipoproteins and methods |
| US5643757A (en) | 1994-03-21 | 1997-07-01 | American Cyanamid Company | High yield production of human apolipoprotein A1 in E. coli. |
| US5766582A (en) | 1994-10-11 | 1998-06-16 | Schering Corporation | Stable, aqueous alfa interferon solution formulations |
| JP2758154B2 (ja) | 1995-04-06 | 1998-05-28 | エフ・ホフマン−ラ ロシユ アーゲー | インターフェロンを含む液体製剤 |
| DE69738397D1 (de) | 1996-08-23 | 2008-01-31 | Esperion Therapeutics Inc | Verfahren zur aufreinigung von apolipoprotein-a oder apolipoprotein-e aus menschlichem plasma |
| AU4142997A (en) | 1996-09-11 | 1998-04-02 | Esperion Therapeutics Inc. | A process for purifying apolipoproteins and a composition for use in the proc ess |
| US6046166A (en) * | 1997-09-29 | 2000-04-04 | Jean-Louis Dasseux | Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders |
| ES2146552B1 (es) | 1998-11-24 | 2001-04-16 | Inst Cientifico Tecnol Navarra | Peptidos inhibidores de tgf/31 |
| US6809186B1 (en) | 1999-01-22 | 2004-10-26 | Martek Biosciences Corporation | Simple method for labeled conjugate production |
| US20020142953A1 (en) * | 2000-04-14 | 2002-10-03 | Ballinger Dennis G. | Materials and methods relating to lipid metabolism |
| AU2008201887B2 (en) * | 2000-11-10 | 2011-06-30 | F. Hoffmann-La Roche Ltd. | Apolipoprotein analogues |
| CN1520259A (zh) | 2001-04-25 | 2004-08-11 | ���ݴ�ѧУ��ίԱ�� | 利用球状载体将第八因子/第九因子进行肝脏基因转移治疗血友病的方法 |
| US8877901B2 (en) | 2002-12-13 | 2014-11-04 | Immunomedics, Inc. | Camptothecin-binding moiety conjugates |
| US7585491B2 (en) | 2002-12-13 | 2009-09-08 | Immunomedics, Inc. | Immunoconjugates with an intracellularly-cleavable linkage |
| US20090011974A1 (en) * | 2002-10-30 | 2009-01-08 | Bocharov Alexander V | Scavenger Receptor B1 (Cla-1) Targeting for the Treatment of Infection, Sepsis and Inflammation |
| TWI369997B (en) | 2003-02-14 | 2012-08-11 | Childrens Hosp & Res Ct Oak | Lipophilic drug delivery vehicle and methods of use thereof |
| JP2004277355A (ja) | 2003-03-17 | 2004-10-07 | Beacle Inc | 血友病治療用薬剤及びそれを用いた血友病治療方法 |
| ES2304069B1 (es) | 2003-08-22 | 2009-08-12 | Proyecto De Biomedicina Cima, S.L. | Peptidos con capacidad de unirse al factor transformante de crecimiento beta 1 (tgf-b1). |
| US7431915B2 (en) * | 2003-10-31 | 2008-10-07 | The Regents Of The University Of California | Peptides whose uptake by cells is controllable |
| US20050255042A1 (en) | 2003-11-24 | 2005-11-17 | The Regents Of The University Of California Office Of Technology Transfer, University Of California | On-demand cleavable linkers for radioconjugates for cancer imaging and therapy |
| EP1718282A4 (en) * | 2004-01-15 | 2010-07-14 | Sinai School Medicine | PROCESS AND COMPOSITIONS FOR IMAGE PRESENTATION |
| AU2005212435B2 (en) * | 2004-02-10 | 2010-09-09 | Biomarin Pharmaceutical Inc. | Acid alpha-glucosidase and fragments thereof |
| US20060051859A1 (en) * | 2004-09-09 | 2006-03-09 | Yan Fu | Long acting human interferon analogs |
| WO2006135436A2 (en) | 2004-10-22 | 2006-12-21 | University Of Florida Research Foundation, Inc. | Inhibition of gene expression and therapeutic uses thereof |
| AU2006232920B2 (en) | 2005-04-06 | 2011-09-29 | Ibc Pharmaceuticals, Inc. | Methods for generating stably linked complexes composed of homodimers, homotetramers or dimers of dimers and uses |
| BRPI0614761A2 (pt) | 2005-08-12 | 2009-05-19 | Human Genome Sciences Inc | proteìnas de fusão de albumina |
| CA2619943A1 (en) | 2005-08-26 | 2007-03-01 | Cerenis Therapeutics Holding Sa | Compositions and methods for producing apolipoprotein gene products in lactic acid bacteria |
| JP5231231B2 (ja) | 2005-10-19 | 2013-07-10 | アイビーシー・ファーマシューティカルズ・インコーポレーテッド | 複雑性が増大した生理活性アセンブリーを生成するための方法および組成物ならびに使用 |
| JP5112322B2 (ja) | 2005-10-24 | 2013-01-09 | プロイェクト、デ、ビオメディシナ、シーマ、ソシエダッド、リミターダ | 免疫応答調節剤の製造におけるTGF−β1インヒビターペプチドの使用 |
| EP1969000A2 (en) | 2005-12-06 | 2008-09-17 | Centre National de la Recherche Scientifique | Cell penetrating peptides for intracellular delivery of molecules |
| US20090238883A1 (en) | 2006-04-28 | 2009-09-24 | Kren Betsy T | Liver-specific nanocapsules and methods of using |
| US20080206142A1 (en) * | 2006-06-16 | 2008-08-28 | Lipid Sciences, Inc. | Novel Peptides That Promote Lipid Efflux |
| US9139611B2 (en) * | 2006-07-13 | 2015-09-22 | Novozymes Biopharma Dk A/S | Process for preparing particles of proteinaceous material |
| KR100817024B1 (ko) * | 2006-11-09 | 2008-03-26 | 재단법인 목암생명공학연구소 | 핵산 또는 약물을 간에 특이적으로 전달하는 복합체 및이를 포함하는 약학적 조성물 |
| US20090110739A1 (en) * | 2007-05-15 | 2009-04-30 | University Of North Texas Health Science Center At Forth Worth | Targeted cancer chemotherapy using synthetic nanoparticles |
| WO2009036460A2 (en) * | 2007-09-14 | 2009-03-19 | Ambrx, Inc. | Modified human apolipoprotein a-i polypeptides and their uses |
-
2009
- 2009-06-12 BR BRPI0915093A patent/BRPI0915093A2/pt not_active Application Discontinuation
- 2009-06-12 AU AU2009256547A patent/AU2009256547B2/en not_active Ceased
- 2009-06-12 US US12/997,829 patent/US20110293557A1/en not_active Abandoned
- 2009-06-12 MX MX2010013759A patent/MX2010013759A/es active IP Right Grant
- 2009-06-12 JP JP2011513010A patent/JP5685529B2/ja not_active Expired - Fee Related
- 2009-06-12 RU RU2011100801/10A patent/RU2567667C2/ru not_active IP Right Cessation
- 2009-06-12 CN CN200980131382.9A patent/CN102123737B/zh not_active Expired - Fee Related
- 2009-06-12 WO PCT/ES2009/070224 patent/WO2009150284A2/es not_active Ceased
- 2009-06-12 EP EP09761841A patent/EP2305309A2/en not_active Withdrawn
- 2009-06-12 CA CA2727811A patent/CA2727811A1/en not_active Abandoned
-
2014
- 2014-10-09 JP JP2014208266A patent/JP2015038124A/ja active Pending
-
2015
- 2015-11-20 US US14/947,164 patent/US20160074475A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| RU2567667C2 (ru) | 2015-11-10 |
| EP2305309A2 (en) | 2011-04-06 |
| AU2009256547B2 (en) | 2014-07-10 |
| AU2009256547A1 (en) | 2009-12-17 |
| JP2015038124A (ja) | 2015-02-26 |
| JP5685529B2 (ja) | 2015-03-18 |
| BRPI0915093A2 (pt) | 2015-10-27 |
| JP2011523857A (ja) | 2011-08-25 |
| CA2727811A1 (en) | 2009-12-17 |
| US20110293557A1 (en) | 2011-12-01 |
| WO2009150284A2 (es) | 2009-12-17 |
| RU2011100801A (ru) | 2012-07-20 |
| WO2009150284A9 (es) | 2011-02-03 |
| CN102123737A (zh) | 2011-07-13 |
| US20160074475A1 (en) | 2016-03-17 |
| WO2009150284A3 (es) | 2010-12-09 |
| CN102123737B (zh) | 2014-01-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU2009256547B2 (en) | Apo-A conjugates for the administration of biologically active compounds | |
| EP1545595B1 (en) | Modified transferrin fusion proteins comprising duplicate transferrin amino or carboxy terminal domains | |
| EP2097096B1 (en) | Modified coagulation factors with prolonged in vivo half-life | |
| EP2814502B1 (en) | Von willebrand factor variants having improved factor viii binding affinity | |
| EP2498799B1 (en) | Use of fgfr1 extra cellular domain proteins to treat cancers characterized by ligand-dependent activating mutations in fgfr2 | |
| EP2502939B1 (en) | Nonnatural collagen-like protein and use thereof | |
| EP2585098B1 (en) | Fzd8 extracellular domains and fzd8 extracellular domain fusion molecules for use in treating obesity and obesity-related disorders | |
| JP2018154644A (ja) | Il−2部分とポリマーとのコンジュゲート | |
| KR20180089516A (ko) | 인터류킨-15 조성물 및 이의 용도 | |
| KR20110111268A (ko) | 면역글로불린 단편을 이용한 인터페론 베타 지속성 제제 | |
| WO2004019872A2 (en) | Oral delivery of modified transferrin fusion proteins | |
| JP2019522962A (ja) | 改善された薬物動態を有する、グリコシル化vwf融合タンパク質 | |
| KR20170026580A (ko) | 변형된 폰 빌레브란트 인자 | |
| CN112601517A (zh) | Fgf-21配制品 | |
| ES2355488T3 (es) | Proteína de fusión de tranferrina modificadas. | |
| US11717577B2 (en) | Method for preparing long-acting drug conjugate through preparation of intermediate | |
| CN110536899A (zh) | 对胰岛素受体具有降低的亲和力的胰岛素类似物复合物及其用途 | |
| US8716446B2 (en) | Biopolymer conjugates comprising an interleukin-11 analog | |
| KR20090103209A (ko) | 사람 인터루킨-2 동종체 | |
| Bae et al. | HM10660A, a long-acting hIFN-α-2b, is a potent candidate for the treatment of hepatitis C through an enhanced biological half-life | |
| KR20250168493A (ko) | 개선된 약동학을 갖는 fviii-vwf 융합 단백질 | |
| HK40067345A (en) | Method for preparing long-acting drug conjugate through preparation of novel intermediate | |
| KR20070016106A (ko) | 인터루킨-1 1 융합 단백질 | |
| CZ20002287A3 (cs) | Komplex IFNAR2/IFN | |
| HK1232439A1 (en) | Modified von willebrand factor |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |