MX2010006854A - Biomarcadores para sensibilidad a terapia anti-receptor-1 del factor de crecimiento tipo insulina. - Google Patents
Biomarcadores para sensibilidad a terapia anti-receptor-1 del factor de crecimiento tipo insulina.Info
- Publication number
- MX2010006854A MX2010006854A MX2010006854A MX2010006854A MX2010006854A MX 2010006854 A MX2010006854 A MX 2010006854A MX 2010006854 A MX2010006854 A MX 2010006854A MX 2010006854 A MX2010006854 A MX 2010006854A MX 2010006854 A MX2010006854 A MX 2010006854A
- Authority
- MX
- Mexico
- Prior art keywords
- biomarkers
- sensitivity
- methods
- igf1r
- therapy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06Q—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES; SYSTEMS OR METHODS SPECIALLY ADAPTED FOR ADMINISTRATIVE, COMMERCIAL, FINANCIAL, MANAGERIAL OR SUPERVISORY PURPOSES, NOT OTHERWISE PROVIDED FOR
- G06Q99/00—Subject matter not provided for in other groups of this subclass
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Theoretical Computer Science (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Hospice & Palliative Care (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Business, Economics & Management (AREA)
- General Business, Economics & Management (AREA)
- General Physics & Mathematics (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
La presente invención proporciona, por ejemplo, métodos para determinar convenientemente si una condición cancerosa en un sujeto será sensible a un inhibidor de IGF1R; la invención incluye métodos de selección de paciente y métodos de tratamiento.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US1455607P | 2007-12-18 | 2007-12-18 | |
US1593807P | 2007-12-21 | 2007-12-21 | |
US2290908P | 2008-01-23 | 2008-01-23 | |
PCT/US2008/087240 WO2009079587A2 (en) | 2007-12-18 | 2008-12-17 | Biomarkers for sensitivity to anti-igf1r therapy |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2010006854A true MX2010006854A (es) | 2010-09-09 |
Family
ID=40796133
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010006854A MX2010006854A (es) | 2007-12-18 | 2008-12-17 | Biomarcadores para sensibilidad a terapia anti-receptor-1 del factor de crecimiento tipo insulina. |
Country Status (6)
Country | Link |
---|---|
US (1) | US20110091524A1 (es) |
EP (1) | EP2247757A2 (es) |
JP (2) | JP2011505873A (es) |
CA (1) | CA2709827A1 (es) |
MX (1) | MX2010006854A (es) |
WO (1) | WO2009079587A2 (es) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006084058A2 (en) | 2005-02-03 | 2006-08-10 | The General Hospital Corporation | Method for treating gefitinib resistant cancer |
TW200803892A (en) | 2005-11-04 | 2008-01-16 | Wyeth Corp | Antineoplastic combinations with MTOR inhibitor, herceptin, and/or HKI-272 |
PE20090368A1 (es) | 2007-06-19 | 2009-04-28 | Boehringer Ingelheim Int | Anticuerpos anti-igf |
US8022216B2 (en) | 2007-10-17 | 2011-09-20 | Wyeth Llc | Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof |
ES2531322T3 (es) | 2008-06-17 | 2015-03-13 | Wyeth Llc | Combinaciones antineoplásicas que contienen HKI-272 y vinorelbina |
NZ590464A (en) | 2008-08-04 | 2012-10-26 | Wyeth Llc | Antineoplastic combinations of the 4-anilino-3-cyanoquinoline neratinib and capecitabine |
NZ597692A (en) | 2008-12-12 | 2013-08-30 | Boehringer Ingelheim Int | Anti-IGF antibodies |
KR20160106211A (ko) | 2009-04-06 | 2016-09-09 | 와이어쓰 엘엘씨 | 네라티닙을 이용한 유방암의 치료법 |
AP3083A (en) * | 2009-11-18 | 2015-01-31 | Helsinn Healthcare Sa | Compositions for treating centrally mediated nausea and vomiting |
WO2011066200A1 (en) * | 2009-11-30 | 2011-06-03 | Merck Sharp & Dohme Corp. | Methods for the identification and treatment of patients sensitive to anti igf-1r inhibition therapy |
US20140037642A1 (en) | 2011-02-02 | 2014-02-06 | Amgen Inc. | Methods and compositions relating to inhibition of igf-1r |
US20120214830A1 (en) | 2011-02-22 | 2012-08-23 | OSI Pharmaceuticals, LLC | Biological markers predictive of anti-cancer response to insulin-like growth factor-1 receptor kinase inhibitors in hepatocellular carcinoma |
WO2012175481A1 (en) * | 2011-06-20 | 2012-12-27 | Institut Curie | Compositions and methods for treating leukemia |
WO2014059196A2 (en) * | 2012-10-10 | 2014-04-17 | The Trustees Of Columbia University In The City Of New York | Diagnosis and treatment of sma and smn deficiency |
CA2890658A1 (en) | 2012-11-09 | 2014-05-15 | The Johns Hopkins University | A genetic assay to determine prognosis in polycythemia vera patients |
US20140255413A1 (en) | 2013-03-07 | 2014-09-11 | Boehringer Ingelheim International Gmbh | Combination therapy for neoplasia treatment |
MX2016002547A (es) | 2013-08-28 | 2016-06-17 | Stemcentrx Inc | Metodos de conjugacion de anticuerpos especificos de sitio y composiciones. |
BR112016018891A2 (pt) * | 2014-02-21 | 2017-10-10 | Abbvie Stemcentrx Llc | anticorpos anti-dll3 e conjugados de fármacos para uso em melanoma |
CN110231482B (zh) * | 2014-08-26 | 2022-07-19 | 学校法人庆应义塾 | 抗癌剂的感受性的判定标记 |
US20170372347A1 (en) * | 2016-06-22 | 2017-12-28 | International Business Machines Corporation | Sequence-based marketing attribution model for customer journeys |
JP2020529870A (ja) * | 2017-08-10 | 2020-10-15 | ザ インスティチュート オブ キャンサー リサーチ,ロイヤル キャンサー ホスピタル | がんを層別化し、処置するための材料及び方法 |
CN107714719A (zh) * | 2017-11-08 | 2018-02-23 | 上海市第妇婴保健院 | 雷帕霉素在制备治疗白细胞介素‑27低表达子宫内膜癌的药物中的应用 |
CN111394462A (zh) * | 2020-04-13 | 2020-07-10 | 浙江大学 | 一种肝癌索拉非尼耐药circRNA标志物及其应用 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5856094A (en) * | 1995-05-12 | 1999-01-05 | The Johns Hopkins University School Of Medicine | Method of detection of neoplastic cells |
US5989885A (en) * | 1997-01-10 | 1999-11-23 | Myriad Genetics, Inc. | Specific mutations of map kinase 4 (MKK4) in human tumor cell lines identify it as a tumor suppressor in various types of cancer |
US20080063639A1 (en) * | 2002-01-18 | 2008-03-13 | Pierre Fabre Medicament | Method for the treatment of psoriasis comprising novel anti-IGF-IR antibodies |
US7553485B2 (en) * | 2002-01-18 | 2009-06-30 | Pierre Fabre Medicament | Anti-IGF-IR and/or anti-insulin/IGF-I hybrid receptors antibodies and uses thereof |
US7241444B2 (en) * | 2002-01-18 | 2007-07-10 | Pierre Fabre Medicament | Anti-IGF-IR antibodies and uses thereof |
US20080193445A1 (en) * | 2002-01-18 | 2008-08-14 | Liliane Goetsch | Novel anti-IGF-IR antibodies and uses thereof |
NZ554740A (en) * | 2002-05-24 | 2009-01-31 | Schering Corp | Neutralizing human anti-IGFR antibody |
US7378503B2 (en) * | 2003-04-02 | 2008-05-27 | Hoffmann-La Roche Inc. | Antibodies against insulin-like growth factor 1 receptor and uses thereof |
BRPI0417302A (pt) * | 2003-12-05 | 2007-03-06 | Compound Therapeutics Inc | inibidores de receptores de fator de crescimento endotelial vascular do tipo 2 |
MX2007006640A (es) * | 2004-12-03 | 2007-06-19 | Schering Corp | Biomarcadores para la preseleccion de pacientes para la terapia con anti-receptor 1 del factor de crecimiento similar a la insulina. |
WO2006113483A2 (en) * | 2005-04-15 | 2006-10-26 | Schering Corporation | Methods and compositions for treating or preventing cancer |
DK1926996T3 (da) * | 2005-09-20 | 2012-01-23 | Osi Pharmaceuticals Llc | Biologiske markører, som er prædiktive for anti-cancer-reaktion på insulinlignende vækstfaktor-1-receptorkinasehæmmere |
US7875274B2 (en) * | 2005-12-16 | 2011-01-25 | The Board Of Trustees Of The Leland Stanford Junior University | Protein modulators of resistance to alkylating agents |
JP5399900B2 (ja) * | 2006-06-30 | 2014-01-29 | メルク・シャープ・アンド・ドーム・コーポレーション | Igfbp2インヒビター |
WO2008076278A2 (en) * | 2006-12-13 | 2008-06-26 | Schering Corporation | Methods of cancer treatment with igf1r inhibitors |
WO2008144345A2 (en) * | 2007-05-17 | 2008-11-27 | Bristol-Myers Squibb Company | Biomarkers and methods for determining sensitivity to insulin growth factor-1 receptor modulators |
-
2008
- 2008-12-17 EP EP08861138A patent/EP2247757A2/en not_active Withdrawn
- 2008-12-17 US US12/808,270 patent/US20110091524A1/en not_active Abandoned
- 2008-12-17 WO PCT/US2008/087240 patent/WO2009079587A2/en active Application Filing
- 2008-12-17 JP JP2010539750A patent/JP2011505873A/ja active Pending
- 2008-12-17 MX MX2010006854A patent/MX2010006854A/es unknown
- 2008-12-17 CA CA2709827A patent/CA2709827A1/en not_active Abandoned
-
2013
- 2013-01-28 JP JP2013012872A patent/JP2013078341A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP2247757A2 (en) | 2010-11-10 |
WO2009079587A3 (en) | 2009-11-12 |
CA2709827A1 (en) | 2009-06-25 |
WO2009079587A2 (en) | 2009-06-25 |
JP2011505873A (ja) | 2011-03-03 |
US20110091524A1 (en) | 2011-04-21 |
JP2013078341A (ja) | 2013-05-02 |
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Legal Events
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HC | Change of company name or juridical status |