MX2009012716A - Nuevas fenilpirrolidinas disustituidas como moduladores de la neurotransmision catecolaminergica cortical. - Google Patents
Nuevas fenilpirrolidinas disustituidas como moduladores de la neurotransmision catecolaminergica cortical.Info
- Publication number
- MX2009012716A MX2009012716A MX2009012716A MX2009012716A MX2009012716A MX 2009012716 A MX2009012716 A MX 2009012716A MX 2009012716 A MX2009012716 A MX 2009012716A MX 2009012716 A MX2009012716 A MX 2009012716A MX 2009012716 A MX2009012716 A MX 2009012716A
- Authority
- MX
- Mexico
- Prior art keywords
- modulators
- phenylpyrrolidines
- new disubstituted
- cortical
- catecholaminergic neurotransmission
- Prior art date
Links
- VDQQJMHXZCMNMU-UHFFFAOYSA-N 1-phenylpyrrolidine Chemical class C1CCCN1C1=CC=CC=C1 VDQQJMHXZCMNMU-UHFFFAOYSA-N 0.000 title 1
- 230000000768 catecholaminergic effect Effects 0.000 title 1
- 230000001054 cortical effect Effects 0.000 title 1
- 230000005062 synaptic transmission Effects 0.000 title 1
- VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 abstract 2
- SFLSHLFXELFNJZ-QMMMGPOBSA-N (-)-norepinephrine Chemical compound NC[C@H](O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-QMMMGPOBSA-N 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000003943 catecholamines Chemical class 0.000 abstract 1
- 208000015114 central nervous system disease Diseases 0.000 abstract 1
- 210000003710 cerebral cortex Anatomy 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229960003638 dopamine Drugs 0.000 abstract 1
- 210000005171 mammalian brain Anatomy 0.000 abstract 1
- 229960002748 norepinephrine Drugs 0.000 abstract 1
- SFLSHLFXELFNJZ-UHFFFAOYSA-N norepinephrine Natural products NCC(O)C1=CC=C(O)C(O)=C1 SFLSHLFXELFNJZ-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Photoreceptors In Electrophotography (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94199307P | 2007-06-05 | 2007-06-05 | |
| SE0701386 | 2007-06-05 | ||
| PCT/EP2008/056912 WO2008148799A1 (en) | 2007-06-05 | 2008-06-04 | New disubstituted phenylpyrrolidines as modulators of cortical catecholaminergic neurotransmission |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009012716A true MX2009012716A (es) | 2009-12-14 |
Family
ID=39672106
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009012716A MX2009012716A (es) | 2007-06-05 | 2008-06-04 | Nuevas fenilpirrolidinas disustituidas como moduladores de la neurotransmision catecolaminergica cortical. |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20100197760A1 (OSRAM) |
| EP (1) | EP2155669B1 (OSRAM) |
| JP (1) | JP2010529080A (OSRAM) |
| CN (1) | CN101711234A (OSRAM) |
| AT (1) | ATE508110T1 (OSRAM) |
| AU (1) | AU2008258597A1 (OSRAM) |
| CA (1) | CA2689692A1 (OSRAM) |
| DE (1) | DE602008006720D1 (OSRAM) |
| MX (1) | MX2009012716A (OSRAM) |
| NZ (1) | NZ581363A (OSRAM) |
| WO (1) | WO2008148799A1 (OSRAM) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20100038295A (ko) | 2007-06-05 | 2010-04-14 | 엔에스아베 필리알 아프 뉴로서치 스웨덴 아베 스베리게 | 피질 카테콜아민성 신경 전달의 조정자로서의 이치환된 페닐피롤리딘 |
| KR101660936B1 (ko) | 2008-11-24 | 2016-10-05 | 인터그레이티브 리서치 래버러토리즈 스웨덴 에이비 | 피질 카테콜아민성 신경전달의 조절자로서의 ３-페닐-３-메톡시피롤리딘 유도체 |
| CN102224135A (zh) | 2008-11-24 | 2011-10-19 | Nsab神经研究瑞典公司分公司 | 用作皮质儿茶酚胺能神经传递调节剂的新3-苯基-氮杂环丁烷衍生物 |
| WO2012134484A1 (en) * | 2011-03-31 | 2012-10-04 | Chevron U.S.A. Inc. | Novel process and catalyst system for improving dewaxing catalyst stability and lubricant oil yield |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2878264A (en) * | 1959-03-17 | Substituted amino alcohols | ||
| US364414A (en) * | 1887-06-07 | Gael hollweg | ||
| US3118907A (en) * | 1961-08-14 | 1964-01-21 | Mead Johnson & Co | 3-substituted-3-pyrrolidinols |
| US3647790A (en) * | 1969-04-08 | 1972-03-07 | American Home Prod | Ouinoxalinyl-oxazolidines and -oxazines |
| JP3176063B2 (ja) * | 1991-04-17 | 2001-06-11 | ファルマシア・アンド・アップジョン・カンパニー | 新規中枢神経作用性置換フェニルアザシクロアルカン類 |
| US5129962A (en) * | 1991-10-22 | 1992-07-14 | International Business Machines Corporation | Tacky, no-clean thermally dissipated soldering flux |
| US20020169155A1 (en) * | 1998-09-04 | 2002-11-14 | Millennium Pharmaceuticals, Inc. | Chemokine receptor anagonists and methods of use therefor |
| SE9904724D0 (sv) | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission I |
| SE9904723D0 (sv) | 1999-12-22 | 1999-12-22 | Carlsson A Research Ab | New modulators of dopamine neurotransmission II |
| TWI308976B (en) * | 2003-02-14 | 2009-04-21 | Chunghwa Picture Tubes Ltd | Process and structure of linquid crystal panel with one drop fill |
| GEP20094705B (en) * | 2003-04-24 | 2009-06-10 | Incyte Corp | Aza spiro alkane derivatives as inhibitors of metalloproteases |
| ATE547404T1 (de) * | 2003-09-22 | 2012-03-15 | Msd Kk | Piperidinderivate |
| TWI350168B (en) * | 2004-05-07 | 2011-10-11 | Incyte Corp | Amido compounds and their use as pharmaceuticals |
| KR100690854B1 (ko) * | 2005-11-08 | 2007-03-09 | 엘지전자 주식회사 | 멀티태스킹이 가능한 휴대용 단말기 및 그의 멀티태스킹처리방법 |
| RU2008129679A (ru) * | 2005-12-21 | 2010-01-27 | Янссен Фармацевтика Н.В. (Be) | Новые замещенные пиразиноновые производные для применения при мсн-1-опосредованных заболеваниях |
| US20080070649A1 (en) * | 2006-09-06 | 2008-03-20 | Uchida Toshi K | Free Space Optical Interconnections in Cellular Telephone Handsets |
-
2008
- 2008-06-04 CA CA2689692A patent/CA2689692A1/en not_active Abandoned
- 2008-06-04 JP JP2010510782A patent/JP2010529080A/ja active Pending
- 2008-06-04 MX MX2009012716A patent/MX2009012716A/es active IP Right Grant
- 2008-06-04 CN CN200880018786A patent/CN101711234A/zh active Pending
- 2008-06-04 US US12/663,211 patent/US20100197760A1/en not_active Abandoned
- 2008-06-04 EP EP08760493A patent/EP2155669B1/en not_active Not-in-force
- 2008-06-04 WO PCT/EP2008/056912 patent/WO2008148799A1/en not_active Ceased
- 2008-06-04 AU AU2008258597A patent/AU2008258597A1/en not_active Abandoned
- 2008-06-04 NZ NZ581363A patent/NZ581363A/en unknown
- 2008-06-04 DE DE602008006720T patent/DE602008006720D1/de active Active
- 2008-06-04 AT AT08760493T patent/ATE508110T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ATE508110T1 (de) | 2011-05-15 |
| DE602008006720D1 (de) | 2011-06-16 |
| EP2155669B1 (en) | 2011-05-04 |
| CA2689692A1 (en) | 2008-12-11 |
| AU2008258597A1 (en) | 2008-12-11 |
| WO2008148799A1 (en) | 2008-12-11 |
| JP2010529080A (ja) | 2010-08-26 |
| CN101711234A (zh) | 2010-05-19 |
| NZ581363A (en) | 2011-10-28 |
| US20100197760A1 (en) | 2010-08-05 |
| EP2155669A1 (en) | 2010-02-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2009012787A (es) | Nuevas fenilpirrolidinas disustituidas como moduladores de neurotransmision catecolaminergica cortical. | |
| EA201071245A1 (ru) | Новые терапевтические подходы для лечения болезни альцгеймера и связанных нарушений посредством модулирования реакции клеток на стресс | |
| PH12012500939A1 (en) | Selective sphingosine 1 phosphate receptor modulators and methods of chiral synthesis | |
| EA201001329A1 (ru) | Соединения и композиции в качестве модуляторов активности gpr119 | |
| TN2010000122A1 (en) | Compounds and compositions as modulators of gpr119 activity | |
| PL2134704T3 (pl) | Związki i kompozycje pełniące rolę modulatorów aktywności GPR119 | |
| EA201001332A1 (ru) | Соединения и композиции в качестве модуляторов активности gpr119 | |
| MY157192A (en) | Pharmaceutical compositions containing dopamine receptor ligands and methods of treatment using dopamine receptor ligands | |
| EP2498609A4 (en) | SELECTIVE HETEROCYCLIC SPHINGOSINE-1-PHOSPHATE RECEPTOR MODULATORS | |
| EA200901032A1 (ru) | Соединения и композиции в качестве модуляторов активности gpr119 | |
| MY160907A (en) | Sphingosine 1 phosphate receptor modulators and methods of chiral synthesis | |
| MX2012004548A (es) | Nuevas composiciones para prevenir y/o tratar transtornos degenerativos del sistema nervioso central. | |
| EA201001330A1 (ru) | Соединения и композиции в качестве модуляторов активности gpr119 | |
| EA201200570A1 (ru) | Соединения и композиции в качестве модуляторов активности gpr119 | |
| CL2011000137A1 (es) | Uso de compuestos derivados de 4,5-dihidro-oxazol-2-ilamina para tratar trastornos de ansiedad, trastornos bipolar, esquizofrenia, enfermedades neurológicas, epilepsias, migraña, trastornos metabólicos, trastornos cardiovasculares, entre otros; compuestos derivados de 4,5-dihidroxazol-2-ilamino; proceso de síntesis | |
| EA201171063A1 (ru) | Фармацевтические составы олмесартана | |
| MX2011013437A (es) | Antagonista y agonistas inversos de histamina h3 y metodos para el uso de los mismos. | |
| MX2011010782A (es) | Compuestos agonistas del receptor 5-ht4 para el tratamiento de trastornos cognitivos. | |
| UY31760A (es) | Tiazolopiridin-2-iloxi-fenil y tiazolopirazin-2-iloxi-fenil aminas como moduladores de leucotrieno a4 hidrolasa | |
| CL2012001031A1 (es) | Compuestos derivados de 2-oxo-1-pirrolidinil-imidazotiadiazol; composición farmacéutica que los comprende; útiles para el tratamiento de la epilepsia, transtornos neurológicos, entre otros. | |
| UA104152C2 (ru) | Производные 3-фенил-3-метоксипирролидина, как модуляторы кортикальной катехоламинергической нейротрансмиссии | |
| MX2009012716A (es) | Nuevas fenilpirrolidinas disustituidas como moduladores de la neurotransmision catecolaminergica cortical. | |
| NZ737451A (en) | Novel azetidine derivatives useful as modulators of cortical catecholaminergic neurotransmission |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |