MX2009012624A - Uso de inhibidores de desacetilasa de histona para el tratamiento de la destruccion osea. - Google Patents

Uso de inhibidores de desacetilasa de histona para el tratamiento de la destruccion osea.

Info

Publication number
MX2009012624A
MX2009012624A MX2009012624A MX2009012624A MX2009012624A MX 2009012624 A MX2009012624 A MX 2009012624A MX 2009012624 A MX2009012624 A MX 2009012624A MX 2009012624 A MX2009012624 A MX 2009012624A MX 2009012624 A MX2009012624 A MX 2009012624A
Authority
MX
Mexico
Prior art keywords
treatment
hdac inhibitors
bone destruction
bone
destruction
Prior art date
Application number
MX2009012624A
Other languages
English (en)
Inventor
Peter Wisdom Atadja
Wenlin Shao
Joseph Daniel Growney
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39643800&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2009012624(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of MX2009012624A publication Critical patent/MX2009012624A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Abstract

La presente invención se refiere al uso de inhibidores de la desacetilasa de histona para el tratamiento de la destrucción ósea causada por cáncer, enfermedades inflamatorias, y osteoporosis.
MX2009012624A 2007-05-30 2008-05-28 Uso de inhibidores de desacetilasa de histona para el tratamiento de la destruccion osea. MX2009012624A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94073507P 2007-05-30 2007-05-30
PCT/US2008/064944 WO2008150782A1 (en) 2007-05-30 2008-05-28 Use of hdac inhibitors for the treatment of bone destruction

Publications (1)

Publication Number Publication Date
MX2009012624A true MX2009012624A (es) 2009-12-07

Family

ID=39643800

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009012624A MX2009012624A (es) 2007-05-30 2008-05-28 Uso de inhibidores de desacetilasa de histona para el tratamiento de la destruccion osea.

Country Status (20)

Country Link
US (2) US20100179208A1 (es)
EP (1) EP2162129B1 (es)
JP (1) JP2010529028A (es)
KR (1) KR101516446B1 (es)
CN (1) CN101715344A (es)
AU (1) AU2008260236A1 (es)
BR (1) BRPI0812788A2 (es)
CA (1) CA2687274A1 (es)
CL (1) CL2008001553A1 (es)
DK (1) DK2162129T3 (es)
ES (1) ES2726401T3 (es)
IL (1) IL201466A0 (es)
LT (1) LT2162129T (es)
MA (1) MA31385B1 (es)
MX (1) MX2009012624A (es)
RU (1) RU2009148601A (es)
SI (1) SI2162129T1 (es)
TN (1) TN2009000448A1 (es)
TW (1) TW200904412A (es)
WO (1) WO2008150782A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009118305A1 (en) 2008-03-26 2009-10-01 Novartis Ag Hydroxamate-based inhibitors of deacetylases b
US20110053925A1 (en) * 2009-08-28 2011-03-03 Novartis Ag Hydroxamate-Based Inhibitors of Deacetylases
CN115778950B (zh) * 2022-11-23 2024-01-26 山西医科大学第二医院 组蛋白去乙酰化酶抑制剂tmp195在制备促进成骨形成药物中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20020354A1 (es) * 2000-09-01 2002-06-12 Novartis Ag Compuestos de hidroxamato como inhibidores de histona-desacetilasa (hda)
PT1912640E (pt) * 2005-08-03 2015-09-22 Novartis Ag Uso do inibidor da hdac panobinostat para o tratamento do mieloma

Also Published As

Publication number Publication date
US20100179208A1 (en) 2010-07-15
IL201466A0 (en) 2010-05-31
US20120029047A1 (en) 2012-02-02
AU2008260236A1 (en) 2008-12-11
KR20100017434A (ko) 2010-02-16
DK2162129T3 (da) 2019-06-11
KR101516446B1 (ko) 2015-04-30
SI2162129T1 (sl) 2019-08-30
BRPI0812788A2 (pt) 2014-12-02
TW200904412A (en) 2009-02-01
LT2162129T (lt) 2019-06-25
CL2008001553A1 (es) 2009-06-05
RU2009148601A (ru) 2011-07-10
EP2162129A1 (en) 2010-03-17
MA31385B1 (fr) 2010-05-03
CA2687274A1 (en) 2008-12-11
TN2009000448A1 (en) 2011-03-31
WO2008150782A1 (en) 2008-12-11
EP2162129B1 (en) 2019-03-06
ES2726401T3 (es) 2019-10-04
CN101715344A (zh) 2010-05-26
JP2010529028A (ja) 2010-08-26

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Legal Events

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HH Correction or change in general