LT2162129T - Hdac inhibitorių panaudojimas kaulų destrukcijos gydymui - Google Patents

Hdac inhibitorių panaudojimas kaulų destrukcijos gydymui

Info

Publication number
LT2162129T
LT2162129T LTEP08756347.4T LT08756347T LT2162129T LT 2162129 T LT2162129 T LT 2162129T LT 08756347 T LT08756347 T LT 08756347T LT 2162129 T LT2162129 T LT 2162129T
Authority
LT
Lithuania
Prior art keywords
treatment
hdac inhibitors
bone destruction
destruction
bone
Prior art date
Application number
LTEP08756347.4T
Other languages
English (en)
Inventor
Peter Atadja
Joseph GROWNEY
Wenlin Shao
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39643800&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LT2162129(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of LT2162129T publication Critical patent/LT2162129T/lt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
LTEP08756347.4T 2007-05-30 2008-05-28 Hdac inhibitorių panaudojimas kaulų destrukcijos gydymui LT2162129T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94073507P 2007-05-30 2007-05-30
PCT/US2008/064944 WO2008150782A1 (en) 2007-05-30 2008-05-28 Use of hdac inhibitors for the treatment of bone destruction

Publications (1)

Publication Number Publication Date
LT2162129T true LT2162129T (lt) 2019-06-25

Family

ID=39643800

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP08756347.4T LT2162129T (lt) 2007-05-30 2008-05-28 Hdac inhibitorių panaudojimas kaulų destrukcijos gydymui

Country Status (20)

Country Link
US (2) US20100179208A1 (lt)
EP (1) EP2162129B1 (lt)
JP (1) JP2010529028A (lt)
KR (1) KR101516446B1 (lt)
CN (1) CN101715344A (lt)
AU (1) AU2008260236A1 (lt)
BR (1) BRPI0812788A2 (lt)
CA (1) CA2687274A1 (lt)
CL (1) CL2008001553A1 (lt)
DK (1) DK2162129T3 (lt)
ES (1) ES2726401T3 (lt)
IL (1) IL201466A0 (lt)
LT (1) LT2162129T (lt)
MA (1) MA31385B1 (lt)
MX (1) MX2009012624A (lt)
RU (1) RU2009148601A (lt)
SI (1) SI2162129T1 (lt)
TN (1) TN2009000448A1 (lt)
TW (1) TW200904412A (lt)
WO (1) WO2008150782A1 (lt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102036955B (zh) 2008-03-26 2013-03-27 诺瓦提斯公司 脱乙酰酶b的异羟肟酸盐为基础的抑制剂
US20110053925A1 (en) * 2009-08-28 2011-03-03 Novartis Ag Hydroxamate-Based Inhibitors of Deacetylases
CN115778950B (zh) * 2022-11-23 2024-01-26 山西医科大学第二医院 组蛋白去乙酰化酶抑制剂tmp195在制备促进成骨形成药物中的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20020354A1 (es) * 2000-09-01 2002-06-12 Novartis Ag Compuestos de hidroxamato como inhibidores de histona-desacetilasa (hda)
HUE028025T2 (en) * 2005-08-03 2016-11-28 Novartis Ag Use of Panobinostat HDAC inhibitor to treat myeloma

Also Published As

Publication number Publication date
SI2162129T1 (sl) 2019-08-30
TW200904412A (en) 2009-02-01
KR101516446B1 (ko) 2015-04-30
MA31385B1 (fr) 2010-05-03
IL201466A0 (en) 2010-05-31
TN2009000448A1 (en) 2011-03-31
BRPI0812788A2 (pt) 2014-12-02
CL2008001553A1 (es) 2009-06-05
CA2687274A1 (en) 2008-12-11
ES2726401T3 (es) 2019-10-04
AU2008260236A1 (en) 2008-12-11
US20120029047A1 (en) 2012-02-02
RU2009148601A (ru) 2011-07-10
EP2162129B1 (en) 2019-03-06
JP2010529028A (ja) 2010-08-26
DK2162129T3 (da) 2019-06-11
KR20100017434A (ko) 2010-02-16
MX2009012624A (es) 2009-12-07
CN101715344A (zh) 2010-05-26
WO2008150782A1 (en) 2008-12-11
EP2162129A1 (en) 2010-03-17
US20100179208A1 (en) 2010-07-15

Similar Documents

Publication Publication Date Title
IL185485A0 (en) Use of pde7 inhibitors for the treatment of neuropathic pain
ZA200807234B (en) GSK-3 inhibitors for the treatment of osteoporosis
IL201309A0 (en) Novel n - (8 - heteroaryltetrahydronaphtalene - 2yl) or n - (5 - heteroarylchromane - 3 - yl) carboxamide derivatives for the treatment of pain
EP2456757A4 (en) HDAC INHIBITORS AND THERAPEUTIC METHODS USING THE SAME
EP2129313A4 (en) SURGICAL INSTRUMENTS AND APPLICATION METHOD THEREFOR
GB0610867D0 (en) Treatment of pain
IL210810A0 (en) Compositions for the treatment of pain and/or inflamtion
EP2139475A4 (en) USE OF PDE7 INHIBITORS IN THE TREATMENT OF
IL193748A0 (en) Treatment of pain
SI1912640T1 (sl) Uporaba inhibitorja hdac panobinostata za zdravljenje mieloma
EP1968505A4 (en) DEVICES AND METHOD FOR THE TREATMENT OF BONE FRACTURES
IL187715A0 (en) Use of phenylsemicarbazones for seed treatment
GB0815632D0 (en) Compositions and methods for promoting the healing of tissue of multicellular organisms
IL210489A0 (en) Use of hdac inhibitors for the treatment of hodgkin's disease
GB0715790D0 (en) Drug combination for the treatment of sialorrhoea
IL192933A0 (en) Benzoisoindole derivatives for the treatment of pain
EP2015741A4 (en) HISTONE DESACETYLASE INHIBITORS FOR THE TREATMENT OF NEURODEGENERATION
EP2007790A4 (en) COMPOUNDS AND METHODS FOR THE TREATMENT OF PAIN
GB0610868D0 (en) Treatment of pain
IL201466A0 (en) Use of hdac inhibitors for the treatment of bone destruction
EP2211771A4 (en) Apparatus for the treatment of gallstones
GB0723100D0 (en) Treatment of HFnEF
ZA200707147B (en) Use of PDE7 inhibitors for the treatment of neuropathic pain
GB0616450D0 (en) Treatment of pain
GB0602857D0 (en) The treatment of sialorrhoea