MX2009011713A - Las composiciones de fosfolipidos para cuidado y conservacion de composiciones farmaceuticas para lentes de contacto. - Google Patents

Las composiciones de fosfolipidos para cuidado y conservacion de composiciones farmaceuticas para lentes de contacto.

Info

Publication number
MX2009011713A
MX2009011713A MX2009011713A MX2009011713A MX2009011713A MX 2009011713 A MX2009011713 A MX 2009011713A MX 2009011713 A MX2009011713 A MX 2009011713A MX 2009011713 A MX2009011713 A MX 2009011713A MX 2009011713 A MX2009011713 A MX 2009011713A
Authority
MX
Mexico
Prior art keywords
compositions
synthetic phospholipids
compounds
pharmaceutical compositions
phospholipids
Prior art date
Application number
MX2009011713A
Other languages
English (en)
Inventor
Masood A Chowhan
Malay Ghosh
Wayne L Schneider
Original Assignee
Alcon Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Res Ltd filed Critical Alcon Res Ltd
Publication of MX2009011713A publication Critical patent/MX2009011713A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A61K31/6615—Compounds having two or more esterified phosphorus acid groups, e.g. inositol triphosphate, phytic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
    • A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
    • A61L12/143—Quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
    • A01N57/10—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds
    • A01N57/12—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-oxygen bonds or phosphorus-to-sulfur bonds containing acyclic or cycloaliphatic radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Wood Science & Technology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Eyeglasses (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

Se describe el uso de ciertos fosfolípidos sintéticos para conservar las composiciones farmacéuticas de contaminación microbiano. Los fosfolípidos sintéticos tienen disposiciones moleculares únicas en donde un grupo fosfato se liga a una funcionalidad de amonio cuaternario vía un grupo propenilo sustituido y la funcionalidad de amonio cuaternario vía un grupo propenilo sustituido y la funcionalidad de amonio cuaternario además se liga a por lo menos una cadena de hidrocarburo larga. Dichas disposiciones moleculares son lo que hacen que los fosfolípidos de la fórmula (I) altamente soluble en agua, v.gr., la longitud de la cadena de hidrocarburos ayuda para mantener solubilidad y eficacia de moléculas para los usos descritos en la presente. Los fosfolípidos sintéticas descritas en la presente se ha encontrado que son particularmente útiles como conservadores antimicrobianos para composiciones farmacéuticas oftálmicas, áticas y nasales, especialmente composiciones oftálmicas. Estos compuestos también se pueden utilizar para desinfectar lentes de contacto. La invención se basa en parte en encontrar que la actividad antimicrobiana de los fosfolípidos sintéticos se afecta por la fuerza jónica de las composiciones en las cuales los compuestos están contenidos.
MX2009011713A 2007-05-18 2008-05-16 Las composiciones de fosfolipidos para cuidado y conservacion de composiciones farmaceuticas para lentes de contacto. MX2009011713A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93893907P 2007-05-18 2007-05-18
PCT/US2008/063877 WO2008144494A1 (en) 2007-05-18 2008-05-16 Phospholipid compositions for contact lens care and preservation of pharmaceutical compositions

Publications (1)

Publication Number Publication Date
MX2009011713A true MX2009011713A (es) 2009-11-10

Family

ID=39627450

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009011713A MX2009011713A (es) 2007-05-18 2008-05-16 Las composiciones de fosfolipidos para cuidado y conservacion de composiciones farmaceuticas para lentes de contacto.

Country Status (15)

Country Link
US (2) US20080287395A1 (es)
EP (1) EP2155271B1 (es)
JP (1) JP5620264B2 (es)
KR (1) KR20100016091A (es)
CN (1) CN101678140A (es)
AR (1) AR066901A1 (es)
AU (1) AU2008254858B2 (es)
BR (1) BRPI0811188A2 (es)
CA (1) CA2683283A1 (es)
CL (1) CL2008001462A1 (es)
ES (1) ES2627437T3 (es)
MX (1) MX2009011713A (es)
TW (1) TW200904485A (es)
UY (1) UY31094A1 (es)
WO (1) WO2008144494A1 (es)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011521957A (ja) * 2008-05-28 2011-07-28 アルコン リサーチ， リミテッド 自己防腐エマルジョン
TW201010727A (en) * 2008-09-03 2010-03-16 Alcon Res Ltd Pharmaceutical composition having relatively low ionic strength
BRPI0923502A2 (pt) * 2008-12-22 2019-09-24 Alcon Res Ltd composições de soluções oculares tópicas para fornecer concentrações eficiêntes de agente ativo no segmento posterior do olho
CN101473832B (zh) * 2009-02-17 2012-05-09 上海斯贝生物科技有限公司 一种新型环保型消毒液
JP2011021002A (ja) * 2009-06-16 2011-02-03 Lion Corp 眼科用組成物
TWI547522B (zh) * 2009-07-07 2016-09-01 愛爾康研究有限公司 環氧乙烷環氧丁烷嵌段共聚物組成物
CA2798069C (en) * 2010-05-05 2016-07-05 Howard Allen Ketelson Stabilized ophthalmic galactomannan formulations
TW201336527A (zh) * 2012-02-10 2013-09-16 Alcon Res Ltd 具增強的穩定性之水性藥學組成物
US10130576B2 (en) * 2012-11-13 2018-11-20 Johnson & Johnson Consumer Inc. Oral care compositions
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WO2021156623A1 (en) 2020-02-07 2021-08-12 Ocutec Limited Optimised contact lens package
CN113729039A (zh) * 2021-08-27 2021-12-03 上海罗克环控节能科技股份有限公司 一种绿色环保消毒液及其制造方法

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Also Published As

Publication number Publication date
AR066901A1 (es) 2009-09-23
US20150209466A1 (en) 2015-07-30
JP5620264B2 (ja) 2014-11-05
TW200904485A (en) 2009-02-01
AU2008254858A1 (en) 2008-11-27
ES2627437T3 (es) 2017-07-28
CN101678140A (zh) 2010-03-24
CL2008001462A1 (es) 2009-01-02
EP2155271A1 (en) 2010-02-24
AU2008254858B2 (en) 2013-06-20
JP2010527933A (ja) 2010-08-19
KR20100016091A (ko) 2010-02-12
US20080287395A1 (en) 2008-11-20
EP2155271B1 (en) 2017-03-08
UY31094A1 (es) 2008-07-03
WO2008144494A1 (en) 2008-11-27
CA2683283A1 (en) 2008-11-27
WO2008144494A8 (en) 2009-12-10
BRPI0811188A2 (pt) 2014-10-07

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