MX2009009503A - Un polipeptido de fusion para deteccion de epitopos combinatorios conservados o compuestos en proteinas no conservadas. - Google Patents
Un polipeptido de fusion para deteccion de epitopos combinatorios conservados o compuestos en proteinas no conservadas.Info
- Publication number
- MX2009009503A MX2009009503A MX2009009503A MX2009009503A MX2009009503A MX 2009009503 A MX2009009503 A MX 2009009503A MX 2009009503 A MX2009009503 A MX 2009009503A MX 2009009503 A MX2009009503 A MX 2009009503A MX 2009009503 A MX2009009503 A MX 2009009503A
- Authority
- MX
- Mexico
- Prior art keywords
- conserved
- combinatorial
- detection
- fusion polypeptide
- proteins
- Prior art date
Links
- 230000004927 fusion Effects 0.000 title abstract 3
- 229920001184 polypeptide Polymers 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 239000002131 composite material Substances 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 239000012472 biological sample Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1036—Retroviridae, e.g. leukemia viruses
- C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
- C07K16/1054—Lentiviridae, e.g. HIV, FIV, SIV gag-pol, e.g. p17, p24
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1058—Directional evolution of libraries, e.g. evolution of libraries is achieved by mutagenesis and screening or selection of mixed population of organisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
- G01N33/56988—HIV or HTLV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/15—Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
- G01N2333/155—Lentiviridae, e.g. visna-maedi virus, equine infectious virus, FIV, SIV
- G01N2333/16—HIV-1, HIV-2
- G01N2333/161—HIV-1, HIV-2 gag-pol, e.g. p55, p24/25, p17/18, p.7, p6, p66/68, p51/52, p31/34, p32, p40
Abstract
La presente invención proporciona polipéptidos de fusión de unión a epítopos múltiples para uso en un método para la detección de la presencia de virus de inmunodeficiencia humana, VIH, en una muestra biológica. La presente invención también proporciona un método para producir polipéptidos de fusión que se unen a epítopos múltiples.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US89342007P | 2007-03-07 | 2007-03-07 | |
FI20075159A FI120349B (fi) | 2007-03-07 | 2007-03-07 | Menetelmä fuusiopolypeptidin valmistamiseksi |
PCT/FI2008/050111 WO2008107523A2 (en) | 2007-03-07 | 2008-03-07 | A fusion polypeptide for detection of conserved combinatorial or composite epitopes in non-conserved proteins |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2009009503A true MX2009009503A (es) | 2010-02-17 |
Family
ID=37930071
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2009009503A MX2009009503A (es) | 2007-03-07 | 2008-03-07 | Un polipeptido de fusion para deteccion de epitopos combinatorios conservados o compuestos en proteinas no conservadas. |
Country Status (9)
Country | Link |
---|---|
US (1) | US8735328B2 (es) |
EP (1) | EP2129689A4 (es) |
JP (1) | JP2010520266A (es) |
CN (1) | CN101679514A (es) |
AU (1) | AU2008223755A1 (es) |
CA (1) | CA2680123A1 (es) |
FI (1) | FI120349B (es) |
MX (1) | MX2009009503A (es) |
WO (1) | WO2008107523A2 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP7176724B2 (ja) | 2018-07-20 | 2022-11-22 | 国立大学法人滋賀医科大学 | ヒト末梢性コリン作動性神経検出用抗体 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NO314588B1 (no) | 2000-09-04 | 2003-04-14 | Bionor Immuno As | HIV-peptider, antigener, vaksinesammensetning, immunoassay- testsett og en fremgangsmåte for å påvise antistoffer indusert av HIV |
US6610472B1 (en) | 2000-10-31 | 2003-08-26 | Genetastix Corporation | Assembly and screening of highly complex and fully human antibody repertoire in yeast |
US6833441B2 (en) | 2001-08-01 | 2004-12-21 | Abmaxis, Inc. | Compositions and methods for generating chimeric heteromultimers |
GB0305702D0 (en) * | 2003-03-12 | 2003-04-16 | Univ Birmingham | Bispecific antibodies |
-
2007
- 2007-03-07 FI FI20075159A patent/FI120349B/fi not_active IP Right Cessation
-
2008
- 2008-03-07 CA CA002680123A patent/CA2680123A1/en not_active Abandoned
- 2008-03-07 EP EP08718564A patent/EP2129689A4/en not_active Withdrawn
- 2008-03-07 US US12/530,019 patent/US8735328B2/en not_active Expired - Fee Related
- 2008-03-07 JP JP2009552239A patent/JP2010520266A/ja not_active Withdrawn
- 2008-03-07 MX MX2009009503A patent/MX2009009503A/es not_active Application Discontinuation
- 2008-03-07 WO PCT/FI2008/050111 patent/WO2008107523A2/en active Application Filing
- 2008-03-07 AU AU2008223755A patent/AU2008223755A1/en not_active Abandoned
- 2008-03-07 CN CN200880015324A patent/CN101679514A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
AU2008223755A1 (en) | 2008-09-12 |
FI120349B (fi) | 2009-09-30 |
CA2680123A1 (en) | 2008-09-12 |
US20100190655A1 (en) | 2010-07-29 |
JP2010520266A (ja) | 2010-06-10 |
FI20075159A (fi) | 2008-09-08 |
EP2129689A1 (en) | 2009-12-09 |
CN101679514A (zh) | 2010-03-24 |
FI20075159A0 (fi) | 2007-03-07 |
WO2008107523A8 (en) | 2009-07-30 |
EP2129689A4 (en) | 2011-11-02 |
US8735328B2 (en) | 2014-05-27 |
WO2008107523A2 (en) | 2008-09-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |