FI20075159A - Fuusiopolypeptidi konservoitujen yhdistelmä- tai komposiittiepitooppien havannointiin ei-konservoituneista proteiineista - Google Patents

Fuusiopolypeptidi konservoitujen yhdistelmä- tai komposiittiepitooppien havannointiin ei-konservoituneista proteiineista Download PDF

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Publication number
FI20075159A
FI20075159A FI20075159A FI20075159A FI20075159A FI 20075159 A FI20075159 A FI 20075159A FI 20075159 A FI20075159 A FI 20075159A FI 20075159 A FI20075159 A FI 20075159A FI 20075159 A FI20075159 A FI 20075159A
Authority
FI
Finland
Prior art keywords
conserved
fusion polypeptide
combination
detecting
proteins
Prior art date
Application number
FI20075159A
Other languages
English (en)
Swedish (sv)
Other versions
FI120349B (fi
FI20075159A0 (fi
Inventor
Kalle Saksela
Original Assignee
Next Biomed Technologies Nbt O
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Next Biomed Technologies Nbt O filed Critical Next Biomed Technologies Nbt O
Publication of FI20075159A0 publication Critical patent/FI20075159A0/fi
Priority to FI20075159A priority Critical patent/FI120349B/fi
Priority to US12/530,019 priority patent/US8735328B2/en
Priority to CA002680123A priority patent/CA2680123A1/en
Priority to EP08718564A priority patent/EP2129689A4/en
Priority to JP2009552239A priority patent/JP2010520266A/ja
Priority to PCT/FI2008/050111 priority patent/WO2008107523A2/en
Priority to CN200880015324A priority patent/CN101679514A/zh
Priority to MX2009009503A priority patent/MX2009009503A/es
Priority to AU2008223755A priority patent/AU2008223755A1/en
Publication of FI20075159A publication Critical patent/FI20075159A/fi
Application granted granted Critical
Publication of FI120349B publication Critical patent/FI120349B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036Retroviridae, e.g. leukemia viruses
    • C07K16/1045Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1054Lentiviridae, e.g. HIV, FIV, SIV gag-pol, e.g. p17, p24
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1037Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1058Directional evolution of libraries, e.g. evolution of libraries is achieved by mutagenesis and screening or selection of mixed population of organisms
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • G01N33/56988HIV or HTLV
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/60Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08RNA viruses
    • G01N2333/15Retroviridae, e.g. bovine leukaemia virus, feline leukaemia virus, feline leukaemia virus, human T-cell leukaemia-lymphoma virus
    • G01N2333/155Lentiviridae, e.g. visna-maedi virus, equine infectious virus, FIV, SIV
    • G01N2333/16HIV-1, HIV-2
    • G01N2333/161HIV-1, HIV-2 gag-pol, e.g. p55, p24/25, p17/18, p.7, p6, p66/68, p51/52, p31/34, p32, p40
FI20075159A 2007-03-07 2007-03-07 Menetelmä fuusiopolypeptidin valmistamiseksi FI120349B (fi)

Priority Applications (9)

Application Number Priority Date Filing Date Title
FI20075159A FI120349B (fi) 2007-03-07 2007-03-07 Menetelmä fuusiopolypeptidin valmistamiseksi
JP2009552239A JP2010520266A (ja) 2007-03-07 2008-03-07 非保存性タンパク質内の、保存性のコンビナトリアルエピトープまたは複合エピトープを検出するための融合ポリペプチド
CA002680123A CA2680123A1 (en) 2007-03-07 2008-03-07 A fusion polypeptide for detection of conserved combinatorial or composite epitopes in non-conserved proteins
EP08718564A EP2129689A4 (en) 2007-03-07 2008-03-07 FUSION POLYPEPTIDE FOR DETECTING COMBINATION OR COMPOSITE EPITOPES PRESERVED IN NON-PRESERVED PROTEINS
US12/530,019 US8735328B2 (en) 2007-03-07 2008-03-07 Fusion polypeptide for detection of conserved combinatorial or composite epitopes in non-conserved proteins
PCT/FI2008/050111 WO2008107523A2 (en) 2007-03-07 2008-03-07 A fusion polypeptide for detection of conserved combinatorial or composite epitopes in non-conserved proteins
CN200880015324A CN101679514A (zh) 2007-03-07 2008-03-07 用于检测非保守蛋白质中保守的组合或复合表位的融合多肽
MX2009009503A MX2009009503A (es) 2007-03-07 2008-03-07 Un polipeptido de fusion para deteccion de epitopos combinatorios conservados o compuestos en proteinas no conservadas.
AU2008223755A AU2008223755A1 (en) 2007-03-07 2008-03-07 A fusion polypeptide for detection of conserved combinatorial or composite epitopes in non-conserved proteins

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI20075159A FI120349B (fi) 2007-03-07 2007-03-07 Menetelmä fuusiopolypeptidin valmistamiseksi
FI20075159 2007-03-07

Publications (3)

Publication Number Publication Date
FI20075159A0 FI20075159A0 (fi) 2007-03-07
FI20075159A true FI20075159A (fi) 2008-09-08
FI120349B FI120349B (fi) 2009-09-30

Family

ID=37930071

Family Applications (1)

Application Number Title Priority Date Filing Date
FI20075159A FI120349B (fi) 2007-03-07 2007-03-07 Menetelmä fuusiopolypeptidin valmistamiseksi

Country Status (9)

Country Link
US (1) US8735328B2 (fi)
EP (1) EP2129689A4 (fi)
JP (1) JP2010520266A (fi)
CN (1) CN101679514A (fi)
AU (1) AU2008223755A1 (fi)
CA (1) CA2680123A1 (fi)
FI (1) FI120349B (fi)
MX (1) MX2009009503A (fi)
WO (1) WO2008107523A2 (fi)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7176724B2 (ja) 2018-07-20 2022-11-22 国立大学法人滋賀医科大学 ヒト末梢性コリン作動性神経検出用抗体

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO314588B1 (no) 2000-09-04 2003-04-14 Bionor Immuno As HIV-peptider, antigener, vaksinesammensetning, immunoassay- testsett og en fremgangsmåte for å påvise antistoffer indusert av HIV
US6610472B1 (en) 2000-10-31 2003-08-26 Genetastix Corporation Assembly and screening of highly complex and fully human antibody repertoire in yeast
US6833441B2 (en) 2001-08-01 2004-12-21 Abmaxis, Inc. Compositions and methods for generating chimeric heteromultimers
GB0305702D0 (en) * 2003-03-12 2003-04-16 Univ Birmingham Bispecific antibodies

Also Published As

Publication number Publication date
AU2008223755A1 (en) 2008-09-12
FI120349B (fi) 2009-09-30
CA2680123A1 (en) 2008-09-12
US20100190655A1 (en) 2010-07-29
MX2009009503A (es) 2010-02-17
JP2010520266A (ja) 2010-06-10
EP2129689A1 (en) 2009-12-09
CN101679514A (zh) 2010-03-24
FI20075159A0 (fi) 2007-03-07
WO2008107523A8 (en) 2009-07-30
EP2129689A4 (en) 2011-11-02
US8735328B2 (en) 2014-05-27
WO2008107523A2 (en) 2008-09-12

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