MX2009006018A - Derivados de quinuclidinol como antagonistas de receptores muscarinicos. - Google Patents
Derivados de quinuclidinol como antagonistas de receptores muscarinicos.Info
- Publication number
- MX2009006018A MX2009006018A MX2009006018A MX2009006018A MX2009006018A MX 2009006018 A MX2009006018 A MX 2009006018A MX 2009006018 A MX2009006018 A MX 2009006018A MX 2009006018 A MX2009006018 A MX 2009006018A MX 2009006018 A MX2009006018 A MX 2009006018A
- Authority
- MX
- Mexico
- Prior art keywords
- sup
- receptor antagonists
- muscarinic receptor
- quinuclidinol derivatives
- quinuclidinol
- Prior art date
Links
- FSNYTEYOTCTPSO-UHFFFAOYSA-N 1-azabicyclo[2.2.2]octan-2-ol Chemical class C1CN2C(O)CC1CC2 FSNYTEYOTCTPSO-UHFFFAOYSA-N 0.000 title 1
- 229940121948 Muscarinic receptor antagonist Drugs 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87063806P | 2006-12-19 | 2006-12-19 | |
| PCT/GB2007/004817 WO2008075005A1 (en) | 2006-12-19 | 2007-12-17 | Quinuclidinol derivatives as muscarinic receptor antagonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009006018A true MX2009006018A (es) | 2009-06-16 |
Family
ID=39166793
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009006018A MX2009006018A (es) | 2006-12-19 | 2007-12-17 | Derivados de quinuclidinol como antagonistas de receptores muscarinicos. |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US20100113510A1 (OSRAM) |
| EP (1) | EP2121137B1 (OSRAM) |
| JP (1) | JP4604129B2 (OSRAM) |
| KR (1) | KR20090094460A (OSRAM) |
| CN (1) | CN101610813A (OSRAM) |
| AR (1) | AR064414A1 (OSRAM) |
| AT (1) | ATE555111T1 (OSRAM) |
| AU (1) | AU2007336054A1 (OSRAM) |
| BR (1) | BRPI0721039A2 (OSRAM) |
| CA (1) | CA2672446A1 (OSRAM) |
| CL (1) | CL2007003690A1 (OSRAM) |
| CO (1) | CO6180439A2 (OSRAM) |
| EC (1) | ECSP099394A (OSRAM) |
| ES (1) | ES2385681T3 (OSRAM) |
| IL (1) | IL199015A0 (OSRAM) |
| MX (1) | MX2009006018A (OSRAM) |
| NO (1) | NO20092689L (OSRAM) |
| PE (1) | PE20081837A1 (OSRAM) |
| RU (1) | RU2009120229A (OSRAM) |
| TW (1) | TW200831507A (OSRAM) |
| UY (1) | UY30803A1 (OSRAM) |
| WO (1) | WO2008075005A1 (OSRAM) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200825084A (en) | 2006-11-14 | 2008-06-16 | Astrazeneca Ab | New compounds 521 |
| GB0808707D0 (en) * | 2008-05-13 | 2008-06-18 | Argenta Discovery Ltd | New compounds 275 |
| JP4837800B2 (ja) | 2008-05-13 | 2011-12-14 | アストラゼネカ・アクチエボラーグ | ムスカリンm3受容体アンタゴニストとしてのキヌクリジン誘導体 |
| WO2009153536A1 (en) * | 2008-06-17 | 2009-12-23 | Argenta Discovery Limited | 1-aza-bicyclo [2.2.2] octane derivatives useful as muscarinic receptor antagonists |
| GB0811100D0 (en) * | 2008-06-17 | 2008-07-23 | Astrazeneca Ab | New combination |
| GB0811099D0 (en) * | 2008-06-17 | 2008-07-23 | Astrazeneca Ab | New combination 376 |
| WO2010008341A1 (en) * | 2008-07-16 | 2010-01-21 | Astrazeneca Ab | A combination of (a) glucocorticoid receptor modulator and (b) a muscarinic antagonist |
| EP2206712A1 (en) * | 2008-12-23 | 2010-07-14 | CHIESI FARMACEUTICI S.p.A. | "Alkaloid aminoester derivatives and medicinal composition thereof" |
| TW201036957A (en) | 2009-02-20 | 2010-10-16 | Astrazeneca Ab | Novel salt 628 |
| WO2010144043A1 (en) * | 2009-06-12 | 2010-12-16 | Astrazeneca Ab | A novel 4-methylbenzenesulphonate salt and a process for preparing a pharmaceutical composition comprising the salt |
| EP2459524A2 (en) | 2009-07-31 | 2012-06-06 | Cadila Healthcare Limited | Novel compounds as modulators of glucocorticoid receptors |
| WO2011073662A1 (en) | 2009-12-17 | 2011-06-23 | Astrazeneca Ab | Combination of a benzoxazinone and a further agent for treating respiratory diseases |
| CA2803433A1 (en) * | 2010-06-22 | 2011-12-29 | Chiesi Farmaceutici S.P.A. | Alkaloid aminoester derivatives and medicinal composition thereof |
| ES2545812T3 (es) * | 2010-06-22 | 2015-09-16 | Chiesi Farmaceutici S.P.A. | Derivados aminoéster de alcaloides y composición medicinal de estos |
| RU2628082C2 (ru) * | 2011-12-30 | 2017-08-14 | КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. | Хинуклидиновые эфиры 1-азагетероциклилуксусной кислоты в качестве антимускариновых средств, способ их получения и их лекарственные композиции |
| EP3023424B1 (en) * | 2013-07-13 | 2019-02-27 | Beijing Shuobai Pharmaceutical Co., Ltd. | Quinine compounds, and optical isomers, preparation method and medical use thereof |
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| GB8334494D0 (en) | 1983-12-24 | 1984-02-01 | Tanabe Seiyaku Co | Carbostyril derivatives |
| GB8923590D0 (en) * | 1989-10-19 | 1989-12-06 | Pfizer Ltd | Antimuscarinic bronchodilators |
| GR1001529B (el) | 1990-09-07 | 1994-03-31 | Elmuquimica Farm Sl | Μέ?οδος για την λήψη νέων 21-εστέρων της 16-17-ακετάλης της πρ να-1,4-διενο-3,20-διόνης. |
| GB9624482D0 (en) | 1995-12-18 | 1997-01-15 | Zeneca Phaema S A | Chemical compounds |
| WO1997030035A1 (en) | 1996-02-13 | 1997-08-21 | Zeneca Limited | Quinazoline derivatives as vegf inhibitors |
| PT885198E (pt) | 1996-03-05 | 2002-06-28 | Astrazeneca Ab | Derivados de 4-anilinoquinazolina |
| GB9718972D0 (en) | 1996-09-25 | 1997-11-12 | Zeneca Ltd | Chemical compounds |
| GB9714249D0 (en) | 1997-07-08 | 1997-09-10 | Angiogene Pharm Ltd | Vascular damaging agents |
| GB9900334D0 (en) | 1999-01-07 | 1999-02-24 | Angiogene Pharm Ltd | Tricylic vascular damaging agents |
| GB9900752D0 (en) | 1999-01-15 | 1999-03-03 | Angiogene Pharm Ltd | Benzimidazole vascular damaging agents |
| AU2001258628A1 (en) | 2000-05-31 | 2001-12-11 | Astrazeneca Ab | Indole derivatives with vascular damaging activity |
| GB0015876D0 (en) | 2000-06-28 | 2000-08-23 | Novartis Ag | Organic compounds |
| BR0112225A (pt) | 2000-07-07 | 2003-05-06 | Angiogene Pharm Ltd | Composto, composição farmacêutica, uso de um composto, e, processo papa preparar um composto |
| MXPA02012905A (es) | 2000-07-07 | 2004-07-30 | Angiogene Pharm Ltd | Derivados de colquinol como agentes de dano vascular.. |
| US7045658B2 (en) | 2001-03-22 | 2006-05-16 | Glaxo Group Limited | Formailide derivatives as beta2-adrenoreceptor agonists |
| CA2445839A1 (en) | 2001-04-30 | 2002-11-07 | Glaxo Group Limited | Anti-inflammatory 17.beta.-carbothioate ester derivatives of androstane with a cyclic ester group in position 17.alpha |
| TWI249515B (en) | 2001-11-13 | 2006-02-21 | Theravance Inc | Aryl aniline beta2 adrenergic receptor agonists |
| US20030229058A1 (en) | 2001-11-13 | 2003-12-11 | Moran Edmund J. | Aryl aniline beta2 adrenergic receptor agonists |
| DE60320439T2 (de) | 2002-10-11 | 2009-05-20 | Pfizer Inc. | INDOLDERIVATE ALS ß2-AGONISTEN |
| US7056916B2 (en) | 2002-11-15 | 2006-06-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Medicaments for the treatment of chronic obstructive pulmonary disease |
| AR044134A1 (es) * | 2003-05-02 | 2005-08-24 | Novartis Ag | Derivados de quinuclidina, metodo de preparacion y composiciones farmaceuticas. |
| CN100445281C (zh) * | 2003-05-02 | 2008-12-24 | 诺瓦提斯公司 | 与毒蕈碱性m3受体结合的奎宁环衍生物 |
| EP1684767A1 (en) | 2003-11-03 | 2006-08-02 | Norton Healthcare Limited | Soft steroid compositions for use in dry powder inhalers |
| MX2007004862A (es) | 2004-10-29 | 2007-05-09 | Astrazeneca Ab | Nuevos derivados de sulfonamida como moduladores del receptor de glucocorticoides para el tratamiento de enfermedades inflamatorias. |
| GB0424284D0 (en) * | 2004-11-02 | 2004-12-01 | Novartis Ag | Organic compounds |
| TW200722418A (en) * | 2005-04-20 | 2007-06-16 | Astrazeneca Ab | Novel compounds |
-
2007
- 2007-12-17 CA CA002672446A patent/CA2672446A1/en not_active Abandoned
- 2007-12-17 BR BRPI0721039-6A patent/BRPI0721039A2/pt not_active IP Right Cessation
- 2007-12-17 CN CNA2007800514963A patent/CN101610813A/zh active Pending
- 2007-12-17 US US12/518,185 patent/US20100113510A1/en not_active Abandoned
- 2007-12-17 ES ES07848557T patent/ES2385681T3/es active Active
- 2007-12-17 RU RU2009120229/15A patent/RU2009120229A/ru not_active Application Discontinuation
- 2007-12-17 WO PCT/GB2007/004817 patent/WO2008075005A1/en not_active Ceased
- 2007-12-17 MX MX2009006018A patent/MX2009006018A/es not_active Application Discontinuation
- 2007-12-17 JP JP2009542194A patent/JP4604129B2/ja not_active Expired - Fee Related
- 2007-12-17 EP EP07848557A patent/EP2121137B1/en active Active
- 2007-12-17 KR KR1020097014992A patent/KR20090094460A/ko not_active Withdrawn
- 2007-12-17 AU AU2007336054A patent/AU2007336054A1/en not_active Abandoned
- 2007-12-17 AT AT07848557T patent/ATE555111T1/de active
- 2007-12-18 AR ARP070105689A patent/AR064414A1/es unknown
- 2007-12-18 UY UY30803A patent/UY30803A1/es unknown
- 2007-12-18 TW TW096148391A patent/TW200831507A/zh unknown
- 2007-12-18 CL CL200703690A patent/CL2007003690A1/es unknown
-
2008
- 2008-01-02 PE PE2008000007A patent/PE20081837A1/es not_active Application Discontinuation
-
2009
- 2009-05-27 IL IL199015A patent/IL199015A0/en unknown
- 2009-05-28 CO CO09054972A patent/CO6180439A2/es not_active Application Discontinuation
- 2009-06-08 EC EC2009009394A patent/ECSP099394A/es unknown
- 2009-07-15 NO NO20092689A patent/NO20092689L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| IL199015A0 (en) | 2010-02-17 |
| ES2385681T3 (es) | 2012-07-30 |
| NO20092689L (no) | 2009-09-14 |
| US20100113510A1 (en) | 2010-05-06 |
| CO6180439A2 (es) | 2010-07-19 |
| EP2121137A1 (en) | 2009-11-25 |
| AR064414A1 (es) | 2009-04-01 |
| KR20090094460A (ko) | 2009-09-07 |
| BRPI0721039A2 (pt) | 2014-07-29 |
| WO2008075005A1 (en) | 2008-06-26 |
| CA2672446A1 (en) | 2008-06-26 |
| CL2007003690A1 (es) | 2008-08-22 |
| RU2009120229A (ru) | 2011-01-27 |
| ECSP099394A (es) | 2009-07-31 |
| JP4604129B2 (ja) | 2010-12-22 |
| AU2007336054A1 (en) | 2008-06-26 |
| JP2010513434A (ja) | 2010-04-30 |
| PE20081837A1 (es) | 2009-02-07 |
| ATE555111T1 (de) | 2012-05-15 |
| UY30803A1 (es) | 2008-07-31 |
| TW200831507A (en) | 2008-08-01 |
| CN101610813A (zh) | 2009-12-23 |
| EP2121137B1 (en) | 2012-04-25 |
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