MX2009003772A - Formulaciones de oximorfona robustas, de liberacion sostenida. - Google Patents

Formulaciones de oximorfona robustas, de liberacion sostenida.

Info

Publication number
MX2009003772A
MX2009003772A MX2009003772A MX2009003772A MX2009003772A MX 2009003772 A MX2009003772 A MX 2009003772A MX 2009003772 A MX2009003772 A MX 2009003772A MX 2009003772 A MX2009003772 A MX 2009003772A MX 2009003772 A MX2009003772 A MX 2009003772A
Authority
MX
Mexico
Prior art keywords
sustained release
release formulations
oxymorphone
formulations
robust
Prior art date
Application number
MX2009003772A
Other languages
English (en)
Inventor
Anand R Baichwal
Steve Labudzinski
Kevin Fitzmaurice
Michelle Howard-Sparks
William Hein
Allen Rychtman
Original Assignee
Penwest Pharmaceuticals Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Penwest Pharmaceuticals Co filed Critical Penwest Pharmaceuticals Co
Publication of MX2009003772A publication Critical patent/MX2009003772A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Se proveen formulaciones robustas de liberación sostenida, formas de dosis sólidas que comprenden las formulaciones robustas de liberación sostenida, y métodos para preparar y usar esas formulaciones y esas formas de dosis sólidas. La robustez de la formulación de liberación sostenida está relacionada con el tamaño de partícula de la goma hidrófila. Las formulaciones de liberación sostenida resisten el vaciado de la dosis cuando se ingieren con alcohol. Las formulaciones son útiles para el tratamiento de un paciente de sufre de una condición, por ejemplo, de dolor. Las formulaciones comprenden por lo menos un fármaco. En una modalidad, el fármaco es un opioide, por ejemplo, oximorfona.
MX2009003772A 2006-10-10 2006-10-10 Formulaciones de oximorfona robustas, de liberacion sostenida. MX2009003772A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2006/039767 WO2008045046A1 (en) 2006-10-10 2006-10-10 Robust sustained release formulations of oxymorphone

Publications (1)

Publication Number Publication Date
MX2009003772A true MX2009003772A (es) 2009-07-22

Family

ID=38169509

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009003772A MX2009003772A (es) 2006-10-10 2006-10-10 Formulaciones de oximorfona robustas, de liberacion sostenida.

Country Status (10)

Country Link
EP (1) EP2097069A1 (es)
JP (1) JP2010505947A (es)
KR (1) KR20090076946A (es)
CN (1) CN101578095A (es)
AU (1) AU2006349471A1 (es)
BR (1) BRPI0621952A2 (es)
CA (1) CA2652980A1 (es)
IL (1) IL198169A0 (es)
MX (1) MX2009003772A (es)
WO (1) WO2008045046A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1551770A (zh) 2001-07-06 2004-12-01 ������ҩ�����޹�˾ 羟吗啡酮控释制剂
JP2010505948A (ja) * 2006-10-10 2010-02-25 ペンウェスト ファーマシューティカルズ カンパニー オキシモルフォンのロバスト性持続放出製剤およびその使用方法
EP3473246A1 (en) 2017-10-19 2019-04-24 Capsugel Belgium NV Immediate release abuse deterrent formulations

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1551770A (zh) * 2001-07-06 2004-12-01 ������ҩ�����޹�˾ 羟吗啡酮控释制剂
BR0205722A (pt) * 2001-07-06 2005-04-05 Penwest Pharmaceuticals Compan Formulação de liberação prolongada e método para o tratamento de um paciente que sofre de dor
CA2459976A1 (en) * 2001-09-26 2003-04-03 Penwest Pharmaceuticals Company Opioid formulations having reduced potential for abuse
JP2010505948A (ja) * 2006-10-10 2010-02-25 ペンウェスト ファーマシューティカルズ カンパニー オキシモルフォンのロバスト性持続放出製剤およびその使用方法

Also Published As

Publication number Publication date
KR20090076946A (ko) 2009-07-13
JP2010505947A (ja) 2010-02-25
CA2652980A1 (en) 2008-04-17
BRPI0621952A2 (pt) 2011-10-18
EP2097069A1 (en) 2009-09-09
AU2006349471A1 (en) 2008-04-17
CN101578095A (zh) 2009-11-11
WO2008045046A1 (en) 2008-04-17
IL198169A0 (en) 2009-12-24

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal