MX2008001328A - Metodos para preparar esteres de carbonato de poli (etilenglicol). - Google Patents

Metodos para preparar esteres de carbonato de poli (etilenglicol).

Info

Publication number
MX2008001328A
MX2008001328A MX2008001328A MX2008001328A MX2008001328A MX 2008001328 A MX2008001328 A MX 2008001328A MX 2008001328 A MX2008001328 A MX 2008001328A MX 2008001328 A MX2008001328 A MX 2008001328A MX 2008001328 A MX2008001328 A MX 2008001328A
Authority
MX
Mexico
Prior art keywords
methods
carbonate esters
poly
preparing carbonate
etylene glycol
Prior art date
Application number
MX2008001328A
Other languages
English (en)
Inventor
Antoni Kozlowski
Jon Mckannan
Samuel P Mcmanus
Original Assignee
Nektar Therapeutics Al Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37600795&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2008001328(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Nektar Therapeutics Al Corp filed Critical Nektar Therapeutics Al Corp
Publication of MX2008001328A publication Critical patent/MX2008001328A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/333—Polymers modified by chemical after-treatment with organic compounds containing nitrogen
    • C08G65/33396—Polymers modified by chemical after-treatment with organic compounds containing nitrogen having oxygen in addition to nitrogen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B47/00—Formation or introduction of functional groups not provided for in groups C07B39/00 - C07B45/00
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/331—Polymers modified by chemical after-treatment with organic compounds containing oxygen
    • C08G65/332—Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides, or esters thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/34—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from hydroxy compounds or their metallic derivatives
    • C08G65/48—Polymers modified by chemical after-treatment
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02—Polyalkylene oxides

Abstract

Se proveen metodos para preparar esteres de carbonato activos de polimeros solubles en agua; tambien se proveen otros metodos relacionados con los esteres de carbonato activos de polimeros solubles en agua, asi como las composiciones correspondientes.
MX2008001328A 2005-07-29 2006-07-31 Metodos para preparar esteres de carbonato de poli (etilenglicol). MX2008001328A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70370905P 2005-07-29 2005-07-29
PCT/US2006/029929 WO2007016560A2 (en) 2005-07-29 2006-07-31 Methods for preparing carbonate esters of poly(etylene glycol)

Publications (1)

Publication Number Publication Date
MX2008001328A true MX2008001328A (es) 2008-04-09

Family

ID=37600795

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2008001328A MX2008001328A (es) 2005-07-29 2006-07-31 Metodos para preparar esteres de carbonato de poli (etilenglicol).

Country Status (16)

Country Link
US (9) US7767784B2 (es)
EP (1) EP1922350B1 (es)
JP (1) JP5544085B2 (es)
KR (1) KR101354244B1 (es)
CN (1) CN101243120B (es)
AU (1) AU2006275473B2 (es)
CA (1) CA2615627C (es)
DK (1) DK1922350T3 (es)
ES (1) ES2529258T3 (es)
HR (1) HRP20150247T1 (es)
MX (1) MX2008001328A (es)
PL (1) PL1922350T3 (es)
PT (1) PT1922350E (es)
RS (1) RS53847B1 (es)
SI (1) SI1922350T1 (es)
WO (1) WO2007016560A2 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1922350E (pt) * 2005-07-29 2015-03-09 Nektar Therapeutics Métodos para preparação de reagentes poliméricos
CN101870767B (zh) * 2009-04-24 2012-09-12 石药集团中奇制药技术（石家庄）有限公司 一种聚乙二醇化的1,2-二脂肪酰磷脂酰乙醇胺的制备方法
EP3053977B1 (en) * 2013-09-30 2019-09-11 Fujimi Incorporated Polishing composition and method for producing same
CA3093645A1 (en) * 2018-03-13 2019-09-19 Nof Corporation Heterobifunctional compound having monodispersed polyethylene glycol in main chain and side chain
JP2022512627A (ja) 2018-10-11 2022-02-07 ネクター セラピューティクス 遊離可能な高分子試薬を作製するための方法
JP7270874B2 (ja) * 2020-04-24 2023-05-11 博唯弘展生技股▲フン▼有限公司 組織癒着防止用温度感受性組成物およびその用途
CN115403760B (zh) * 2021-05-26 2023-10-03 博唯弘展生技股份有限公司 用于预防沾粘的氨基酸改质的聚合物及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5281698A (en) * 1991-07-23 1994-01-25 Cetus Oncology Corporation Preparation of an activated polymer ester for protein conjugation
US5629384A (en) 1994-05-17 1997-05-13 Consiglio Nazionale Delle Ricerche Polymers of N-acryloylmorpholine activated at one end and conjugates with bioactive materials and surfaces
US5693609A (en) 1994-11-17 1997-12-02 Eli Lilly And Company Acylated insulin analogs
US5932462A (en) 1995-01-10 1999-08-03 Shearwater Polymers, Inc. Multiarmed, monofunctional, polymer for coupling to molecules and surfaces
ATE268609T1 (de) 1998-03-12 2004-06-15 Nektar Therapeutics Al Corp Polyethylenglycolderivate mit benachbarten reaktiven gruppen
US6348558B1 (en) * 1999-12-10 2002-02-19 Shearwater Corporation Hydrolytically degradable polymers and hydrogels made therefrom
WO2001045796A2 (en) * 1999-12-22 2001-06-28 Shearwater Corporation Method for the preparation of 1-benzotriazolyl carbonate esters of poly(ethylene glycol)
US6413507B1 (en) * 1999-12-23 2002-07-02 Shearwater Corporation Hydrolytically degradable carbamate derivatives of poly (ethylene glycol)
CN100558398C (zh) * 2002-11-26 2009-11-11 拜奥康有限公司 修饰的钠尿化合物、缀合物及其应用
PT1922350E (pt) 2005-07-29 2015-03-09 Nektar Therapeutics Métodos para preparação de reagentes poliméricos

Also Published As

Publication number Publication date
US20120214952A1 (en) 2012-08-23
US7767784B2 (en) 2010-08-03
US20190375892A1 (en) 2019-12-12
HRP20150247T1 (hr) 2015-04-10
US8193306B2 (en) 2012-06-05
CA2615627C (en) 2014-10-21
DK1922350T3 (en) 2015-03-09
JP2009503201A (ja) 2009-01-29
US8461295B2 (en) 2013-06-11
AU2006275473B2 (en) 2012-07-05
EP1922350A2 (en) 2008-05-21
US20170283552A1 (en) 2017-10-05
US8809489B2 (en) 2014-08-19
EP1922350B1 (en) 2015-01-07
PT1922350E (pt) 2015-03-09
WO2007016560A2 (en) 2007-02-08
ES2529258T3 (es) 2015-02-18
PL1922350T3 (pl) 2015-07-31
US20080064851A1 (en) 2008-03-13
CA2615627A1 (en) 2007-02-08
US20210130546A1 (en) 2021-05-06
SI1922350T1 (sl) 2015-04-30
JP5544085B2 (ja) 2014-07-09
WO2007016560A3 (en) 2007-04-12
AU2006275473A1 (en) 2007-02-08
CN101243120A (zh) 2008-08-13
KR20080034485A (ko) 2008-04-21
US9732189B2 (en) 2017-08-15
US10421838B2 (en) 2019-09-24
US20130253203A1 (en) 2013-09-26
RS53847B1 (en) 2015-08-31
CN101243120B (zh) 2012-04-18
US20100256310A1 (en) 2010-10-07
WO2007016560A9 (en) 2007-05-31
KR101354244B1 (ko) 2014-02-18
US20160289382A1 (en) 2016-10-06
US20140323742A1 (en) 2014-10-30
US9334364B2 (en) 2016-05-10

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