MX2007015958A - Composiciones de peptido lkktet y/o lkktnt, y metodos. - Google Patents

Composiciones de peptido lkktet y/o lkktnt, y metodos.

Info

Publication number
MX2007015958A
MX2007015958A MX2007015958A MX2007015958A MX2007015958A MX 2007015958 A MX2007015958 A MX 2007015958A MX 2007015958 A MX2007015958 A MX 2007015958A MX 2007015958 A MX2007015958 A MX 2007015958A MX 2007015958 A MX2007015958 A MX 2007015958A
Authority
MX
Mexico
Prior art keywords
agent
lkktet
lkktnt
composition
methods
Prior art date
Application number
MX2007015958A
Other languages
English (en)
Spanish (es)
Inventor
Allan L Goldstein
David Crockford
Gabriel Sosne
Ewald Hanna Ppel
Original Assignee
Regenerx Biopharmaceuticals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Regenerx Biopharmaceuticals filed Critical Regenerx Biopharmaceuticals
Publication of MX2007015958A publication Critical patent/MX2007015958A/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/2292Thymosin; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/04Artificial tears; Irrigation solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/14Decongestants or antiallergics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Cosmetics (AREA)
MX2007015958A 2005-06-17 2006-06-19 Composiciones de peptido lkktet y/o lkktnt, y metodos. MX2007015958A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US69126105P 2005-06-17 2005-06-17
US77694706P 2006-02-28 2006-02-28
PCT/US2006/023760 WO2006138709A2 (en) 2005-06-17 2006-06-19 Lkktet and/or lkktnt peptide compositions and methods

Publications (1)

Publication Number Publication Date
MX2007015958A true MX2007015958A (es) 2008-04-17

Family

ID=37570786

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2007015958A MX2007015958A (es) 2005-06-17 2006-06-19 Composiciones de peptido lkktet y/o lkktnt, y metodos.
MX2007015956A MX2007015956A (es) 2005-06-17 2006-06-19 Composiciones de lkktet y/o lkktnt para tratar o prevenir el deterioro, lesion o dano a tejido.
MX2007015957A MX2007015957A (es) 2005-06-17 2006-06-19 Composiciones de peptido lkktet y/o lkktnt que estan liofilizadas o en una forma capaz de ser liofilizada.

Family Applications After (2)

Application Number Title Priority Date Filing Date
MX2007015956A MX2007015956A (es) 2005-06-17 2006-06-19 Composiciones de lkktet y/o lkktnt para tratar o prevenir el deterioro, lesion o dano a tejido.
MX2007015957A MX2007015957A (es) 2005-06-17 2006-06-19 Composiciones de peptido lkktet y/o lkktnt que estan liofilizadas o en una forma capaz de ser liofilizada.

Country Status (11)

Country Link
US (8) US20090131313A1 (https=)
EP (4) EP1896050A4 (https=)
JP (3) JP2008543878A (https=)
KR (3) KR20080033939A (https=)
CN (1) CN105106931A (https=)
AU (3) AU2006261157A1 (https=)
CA (3) CA2612522A1 (https=)
HK (1) HK1218248A1 (https=)
IL (4) IL187522A0 (https=)
MX (3) MX2007015958A (https=)
WO (3) WO2006138709A2 (https=)

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CA2718774A1 (en) * 2008-03-17 2009-12-17 Regenerx Biopharmaceuticals, Inc. Improved beta thymosin fragments
CN101297965B (zh) * 2008-06-16 2011-01-05 浙江省中医药研究院 胸腺肽β4在制备防治支气管哮喘药物中的应用
WO2011044589A2 (en) * 2009-10-09 2011-04-14 Board Of Regents, The University Of Texas System Photokinetic ocular drug delivery methods and apparatus
WO2012126047A1 (en) * 2011-03-18 2012-09-27 Adistem Ltd Agent and method for treating pain and reducing inflammation
DK2819682T3 (en) 2012-03-01 2017-08-21 Firststring Res Inc TOPICAL GELLS CONTAINING ALPHA-CONNEXIN C-TERMINAL (ACT) PEPTIDES
EP2698162A1 (en) 2012-08-15 2014-02-19 Credentis AG Method for producing a composition for treating a tooth lesion
AU2014345802B2 (en) * 2013-11-07 2018-01-25 Dr. August Wolff Gmbh & Co. Kg Arzneimittel Storage stable lyophilized tripeptide formulations
CA2942035A1 (en) 2014-03-12 2015-09-17 University Of Virginia Patent Foundation Compositions and methods for treating eye infections and disease
WO2016064078A1 (ko) 2014-10-22 2016-04-28 주식회사 지트리비앤티 티모신 베타 4를 함유하는 조성물 및 이를 포함하는 약학적 제형
MA41299A (fr) * 2014-12-30 2017-11-07 Axim Biotechnologies Inc Solutions ophtalmiques pour le traitement du glaucome et de la conjonctivite
US9867868B2 (en) 2015-08-18 2018-01-16 G-Treebnt Co., Ltd. Pharmaceutical composition for treating or preventing corneal wound comprising thymosin β4 and citric acid
KR20170021667A (ko) 2015-08-18 2017-02-28 주식회사 지트리비앤티 티모신 β4를 유효성분으로 포함하는 신경영양성각막염 치료용 조성물
JP6996713B2 (ja) * 2015-10-06 2022-02-04 エイチエルビー・セラピューティクス・カンパニー・リミテッド チモシンベータ4を含む眼科用製剤の製造方法
CA3031069A1 (en) * 2016-07-18 2018-01-25 Regentree, Llc Methods of treating dry eye syndrome
KR102115158B1 (ko) 2016-11-29 2020-05-26 주식회사 지트리파마슈티컬 티모신 베타 4 를 함유하는 제형
KR20250023579A (ko) * 2017-02-21 2025-02-18 티얼솔루션즈, 인크. 안정한 펩타이드 조성물
KR102340750B1 (ko) * 2017-03-03 2021-12-21 에이치엘비테라퓨틱스 주식회사 티모신 베타 4를 유효성분으로 포함하는 안정화된 외용 제제
KR101910908B1 (ko) * 2017-06-14 2018-10-24 (주)휴온스 Gly-Tβ4 (Gly-티모신β4)을 함유하는 안구건조증 치료용 약학적 조성물
US10342824B2 (en) 2017-07-17 2019-07-09 Dr. Marlowe's Weight Loss Institute, P.L.L.C. Supplement for treating side effects of medications which cause metabolic acidosis
CN111386337A (zh) * 2017-11-24 2020-07-07 Gtreebnt科技有限公司 包含胸腺素β4或其衍生物作为活性成分的用于促进杯状细胞增殖或粘蛋白分泌的组合物
MX2023004631A (es) 2020-10-22 2023-07-20 Xequel Bio Inc Formulaciones peptidicas y usos oftalmicos de las mismas.
WO2024006653A2 (en) * 2022-07-01 2024-01-04 Tearsolutions, Inc. Stable peptide compositions and methods of use thereof for treatment of moderate/severe dry eye-related ocular symptoms

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US4444757A (en) * 1981-11-16 1984-04-24 Research Corporation Use of thymosin as an anti-diabetes and anti-hypertensive disease agent
US4906613A (en) 1985-11-05 1990-03-06 Schering Corporation Antiglaucoma compositions and methods
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JP2005502672A (ja) * 2001-08-29 2005-01-27 リジェナークス・バイオファーマスーティカルズ・インコーポレイテッド サイモシンβ4、類似体、アイソフォームおよびその他の誘導体を用いて心筋障害の発生前、発生中または発生後に発生する炎症、損傷およびその他の変化を治癒または予防する方法
US20040005644A1 (en) * 2002-02-28 2004-01-08 Su Yan A. Method and composition for detection and treatment of breast cancer
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EP1613369A4 (en) * 2003-03-31 2008-10-01 Regenerx Biopharmaceuticals COMPOSITIONS AND METHODS OF DELIVERING THYMOSINE BETA 4, ANALOGUE, ISOFORMS AND OTHER DERIVATIVES
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Also Published As

Publication number Publication date
US20090131313A1 (en) 2009-05-21
AU2006261157A1 (en) 2006-12-28
CA2612410A1 (en) 2006-12-28
WO2006138708A1 (en) 2006-12-28
WO2006138709A2 (en) 2006-12-28
IL218504A (en) 2013-10-31
US20170128540A1 (en) 2017-05-11
JP2008543878A (ja) 2008-12-04
JP2008543879A (ja) 2008-12-04
US20120071411A1 (en) 2012-03-22
US20090118196A1 (en) 2009-05-07
IL218504A0 (en) 2012-04-30
IL187781A0 (en) 2008-08-07
IL187522A0 (en) 2008-03-20
US20160193301A1 (en) 2016-07-07
AU2006261155A1 (en) 2006-12-28
US9821030B2 (en) 2017-11-21
CA2612405A1 (en) 2006-12-28
KR20080021782A (ko) 2008-03-07
MX2007015956A (es) 2008-03-06
US20180028619A1 (en) 2018-02-01
IL187617A0 (en) 2008-03-20
EP1896050A2 (en) 2008-03-12
EP1906986A1 (en) 2008-04-09
KR20080033939A (ko) 2008-04-17
US9585941B2 (en) 2017-03-07
EP1904080A1 (en) 2008-04-02
US8383576B2 (en) 2013-02-26
US20160287673A1 (en) 2016-10-06
CN105106931A (zh) 2015-12-02
JP2008543877A (ja) 2008-12-04
WO2006138708B1 (en) 2007-04-05
EP1896050A4 (en) 2010-01-27
US10004785B2 (en) 2018-06-26
WO2006138709A3 (en) 2007-07-05
IL187781A (en) 2012-04-30
WO2006138707A1 (en) 2006-12-28
AU2006261156A1 (en) 2006-12-28
EP1906986A4 (en) 2011-02-23
EP3326647A1 (en) 2018-05-30
AU2006261156B2 (en) 2012-05-31
CA2612522A1 (en) 2006-12-28
US20080214456A1 (en) 2008-09-04
HK1218248A1 (zh) 2017-02-10
KR20080018268A (ko) 2008-02-27
MX2007015957A (es) 2008-03-06
EP1904080A4 (en) 2011-02-16

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