MX2007015511A - Sales novedosas de farmacos sicotropicos conjugados y procesos para prepararlas. - Google Patents
Sales novedosas de farmacos sicotropicos conjugados y procesos para prepararlas.Info
- Publication number
- MX2007015511A MX2007015511A MX2007015511A MX2007015511A MX2007015511A MX 2007015511 A MX2007015511 A MX 2007015511A MX 2007015511 A MX2007015511 A MX 2007015511A MX 2007015511 A MX2007015511 A MX 2007015511A MX 2007015511 A MX2007015511 A MX 2007015511A
- Authority
- MX
- Mexico
- Prior art keywords
- acid
- residue
- chemical
- addition salt
- conjugate
- Prior art date
Links
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
- C07D279/18—[b, e]-condensed with two six-membered rings
- C07D279/22—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom
- C07D279/24—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom
- C07D279/28—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom with hydrocarbon radicals, substituted by amino radicals, attached to the ring nitrogen atom with other substituents attached to the ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (3)
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|---|---|---|---|
| US68785105P | 2005-06-07 | 2005-06-07 | |
| US79450106P | 2006-04-25 | 2006-04-25 | |
| PCT/IL2006/000666 WO2006131923A2 (en) | 2005-06-07 | 2006-06-07 | Novel salts of conjugated psychotropic drugs and processes of preparing same |
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| MX2007015511A true MX2007015511A (es) | 2008-03-06 |
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| MX2007015511A MX2007015511A (es) | 2005-06-07 | 2006-06-07 | Sales novedosas de farmacos sicotropicos conjugados y procesos para prepararlas. |
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|---|---|
| US (1) | US20090298814A1 (https=) |
| EP (1) | EP1888120B1 (https=) |
| JP (1) | JP5284779B2 (https=) |
| AU (1) | AU2006256369B2 (https=) |
| CA (1) | CA2610838A1 (https=) |
| ES (1) | ES2400772T3 (https=) |
| MX (1) | MX2007015511A (https=) |
| WO (1) | WO2006131923A2 (https=) |
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| US7544681B2 (en) | 2001-09-27 | 2009-06-09 | Ramot At Tel Aviv University Ltd. | Conjugated psychotropic drugs and uses thereof |
| CN101506188B (zh) * | 2006-06-22 | 2014-01-15 | 雷蒙特亚特特拉维夫大学有限公司 | 作为具外周系统限制活性药物的五羟色胺再摄取抑制剂 |
| US9278947B2 (en) | 2006-06-22 | 2016-03-08 | Ramot At Tel-Aviv University Ltd. | Serotonin reuptake inhibitors as drugs having peripheral-system-restricted activity |
| EP2051735B1 (en) | 2006-07-17 | 2012-08-29 | Ramot, at Tel Aviv University Ltd. | Conjugates comprising a psychotropic drug or a gaba agonist and an organic acid and their use treating pain and other cns disorders |
| WO2009101616A1 (en) | 2008-02-11 | 2009-08-20 | Ramot At Tel Aviv University Ltd. | Novel conjugates for treating neurodegenerative diseases and disorders |
| WO2011070579A1 (en) * | 2009-12-09 | 2011-06-16 | Biolinerx Ltd. | Methods of improving cognitive functions |
| US8377929B2 (en) * | 2010-02-24 | 2013-02-19 | Ramot At Tel-Aviv University Ltd. | Crystalline forms of the tri-mesylate salt of perphenazine-GABA and process of producing the same |
| WO2012038963A1 (en) | 2010-09-22 | 2012-03-29 | Ramot At Tel-Aviv University Ltd. | An acid addition salt of a nortriptyline-gaba conjugate and a process of preparing same |
| US11407721B2 (en) | 2013-02-19 | 2022-08-09 | Amgen Inc. | CIS-morpholinone and other compounds as MDM2 inhibitors for the treatment of cancer |
| CN105358530A (zh) * | 2013-06-10 | 2016-02-24 | 美国安进公司 | 制备mdm2抑制剂的方法及其结晶形式 |
| US12459965B2 (en) | 2017-10-09 | 2025-11-04 | Compass Pathfinder Limited | Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use |
| GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
| KR20220009954A (ko) | 2019-04-17 | 2022-01-25 | 컴퍼스 패쓰파인더 리미티드 | 신경인지 장애, 만성 통증을 치료하고 염증을 감소시키는 방법 |
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| US2944053A (en) * | 1960-07-05 | Uiiilcu | ||
| US2914528A (en) * | 1958-04-16 | 1959-11-24 | Smith Kline French Lab | Substituted phenothiazinyl trifluoro-methyl sulfones |
| NL227699A (https=) * | 1957-09-11 | 1900-01-01 | ||
| US2969358A (en) * | 1958-12-08 | 1961-01-24 | Searle & Co | 2-chloro-10-phenothiazinecarbonylpiperazines |
| US3956492A (en) * | 1972-07-12 | 1976-05-11 | Boehringer Ingelheim Gmbh | Pharmaceutical compositions containing a 3-(amino-methylene)-5-phenyl-1,4-benzodiazepin-2-one and method of use |
| GB1460713A (en) * | 1973-06-08 | 1977-01-06 | Kefalas As | 7-fluoro substituted phenothiazines method for preparation thereof and compositions bladed rotor for a gas turbine engine |
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2006
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- 2006-06-07 ES ES06756205T patent/ES2400772T3/es active Active
- 2006-06-07 MX MX2007015511A patent/MX2007015511A/es active IP Right Grant
- 2006-06-07 CA CA002610838A patent/CA2610838A1/en not_active Abandoned
- 2006-06-07 WO PCT/IL2006/000666 patent/WO2006131923A2/en not_active Ceased
- 2006-06-07 US US11/921,578 patent/US20090298814A1/en not_active Abandoned
- 2006-06-07 EP EP06756205A patent/EP1888120B1/en not_active Not-in-force
- 2006-06-07 AU AU2006256369A patent/AU2006256369B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU2006256369B2 (en) | 2012-08-02 |
| JP2008545777A (ja) | 2008-12-18 |
| JP5284779B2 (ja) | 2013-09-11 |
| WO2006131923A3 (en) | 2007-08-02 |
| EP1888120A2 (en) | 2008-02-20 |
| EP1888120B1 (en) | 2012-12-05 |
| WO2006131923A2 (en) | 2006-12-14 |
| ES2400772T3 (es) | 2013-04-12 |
| AU2006256369A1 (en) | 2006-12-14 |
| US20090298814A1 (en) | 2009-12-03 |
| CA2610838A1 (en) | 2006-12-14 |
| AU2006256369A8 (en) | 2006-12-14 |
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