MX2007014830A - Metodos y formulaciones para aumentar la absorcion y disminuir la variabilidad de absorcion de farmacos, vitaminas y nutrientes oralmente administrados. - Google Patents
Metodos y formulaciones para aumentar la absorcion y disminuir la variabilidad de absorcion de farmacos, vitaminas y nutrientes oralmente administrados.Info
- Publication number
- MX2007014830A MX2007014830A MX2007014830A MX2007014830A MX2007014830A MX 2007014830 A MX2007014830 A MX 2007014830A MX 2007014830 A MX2007014830 A MX 2007014830A MX 2007014830 A MX2007014830 A MX 2007014830A MX 2007014830 A MX2007014830 A MX 2007014830A
- Authority
- MX
- Mexico
- Prior art keywords
- absorption
- nutrients
- vitamins
- formulations
- enhancing
- Prior art date
Links
- 229940079593 drug Drugs 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 238000010521 absorption reaction Methods 0.000 title 2
- 230000003247 decreasing effect Effects 0.000 title 1
- 230000002708 enhancing effect Effects 0.000 title 1
- 238000009472 formulation Methods 0.000 title 1
- 235000015097 nutrients Nutrition 0.000 title 1
- 235000013343 vitamin Nutrition 0.000 title 1
- 229940088594 vitamin Drugs 0.000 title 1
- 229930003231 vitamin Natural products 0.000 title 1
- 239000011782 vitamin Substances 0.000 title 1
- 239000002904 solvent Substances 0.000 abstract 2
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 abstract 1
- 229930182558 Sterol Natural products 0.000 abstract 1
- 230000002209 hydrophobic effect Effects 0.000 abstract 1
- 229940067606 lecithin Drugs 0.000 abstract 1
- 235000010445 lecithin Nutrition 0.000 abstract 1
- 239000000787 lecithin Substances 0.000 abstract 1
- 235000003702 sterols Nutrition 0.000 abstract 1
- 150000003432 sterols Chemical class 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/10—Foods or foodstuffs containing additives; Preparation or treatment thereof containing emulsifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Dispersion Chemistry (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se describe un método y la composición para preparar fármacos pobremente solubles en agua, hidrofóbicos, biodisponibles. Este utiliza por ejemplo, lecitina, esterol y solvente; se mezclan y luego el solvente se elimina, las proporciones utilizadas difieren unas de otras, y se eleva al máximo el funcionamiento.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/563,356 US20080124387A1 (en) | 2006-11-27 | 2006-11-27 | Methods and formulations for enhancing the absorption and decreasing the absorption variability of orally administered drugs, vitamins and nutrients |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2007014830A true MX2007014830A (es) | 2009-02-19 |
Family
ID=39148632
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2007014830A MX2007014830A (es) | 2006-11-27 | 2007-11-26 | Metodos y formulaciones para aumentar la absorcion y disminuir la variabilidad de absorcion de farmacos, vitaminas y nutrientes oralmente administrados. |
Country Status (8)
Country | Link |
---|---|
US (3) | US20080124387A1 (es) |
EP (1) | EP1925294B1 (es) |
JP (1) | JP5225663B2 (es) |
AU (1) | AU2008203553B2 (es) |
BR (1) | BRPI0704205A2 (es) |
CA (1) | CA2612128C (es) |
ES (1) | ES2535076T3 (es) |
MX (1) | MX2007014830A (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2200613B1 (en) | 2007-09-21 | 2018-09-05 | The Johns Hopkins University | Phenazine derivatives and uses thereof |
US20090088393A1 (en) * | 2007-09-28 | 2009-04-02 | Zomanex, Llc | Methods and formulations for converting intravenous and injectable drugs into oral dosage forms |
CN101888787A (zh) * | 2007-12-05 | 2010-11-17 | 帝斯曼知识产权资产管理有限公司 | 脂溶性活性成分的粉状制剂 |
CA2822435C (en) * | 2009-12-31 | 2018-09-11 | Differential Drug Development Associates, Llc | Modulation of solubility, stability, absorption, metabolism, and pharmacokinetic profile of lipophilic drugs by sterols |
US20130303495A1 (en) * | 2009-12-31 | 2013-11-14 | Sov Therapeutics | Emulsion formulations |
ES2875458T3 (es) | 2010-12-29 | 2021-11-10 | Abbott Lab | Producto nutricional para uso en la reducción de la incidencia de enterocolitis necrosante en un lactante, niño pequeño o niño |
WO2014132134A1 (en) * | 2013-02-28 | 2014-09-04 | Pronova Biopharma Norge As | A composition comprising a lipid compound, a triglyceride, and a surfactant, and methods of using the same |
CN105188670B (zh) | 2013-03-15 | 2018-11-02 | 马留斯医药有限责任公司 | 乳液制剂 |
WO2015153449A1 (en) | 2014-03-31 | 2015-10-08 | Redshift Systems Corporation | Fluid analyzer with modulation for liquids and gases |
CA2963881C (en) * | 2014-10-17 | 2022-05-03 | Raisio Nutrition Ltd | Cholesterol lowering capsules |
JP6211220B1 (ja) * | 2017-01-26 | 2017-10-11 | アピ株式会社 | カプセル用アントシアニン含有組成物及びカプセル剤 |
Family Cites Families (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH621479A5 (es) | 1977-08-05 | 1981-02-13 | Battelle Memorial Institute | |
FR2416008A1 (fr) | 1978-02-02 | 1979-08-31 | Oreal | Lyophilisats de liposomes |
FR2521565B1 (fr) | 1982-02-17 | 1985-07-05 | Dior Sa Parfums Christian | Melange pulverulent de constituants lipidiques et de constituants hydrophobes, procede pour le preparer, phases lamellaires lipidiques hydratees et procede de fabrication, compositions pharmaceutiques ou cosmetiques comportant des phases lamellaires lipidiques hydratees |
FR2534487B1 (fr) | 1982-10-15 | 1988-06-10 | Dior Christian Parfums | Procede d'homogeneisation de dispersions de phases lamellaires lipidiques hydratees, et suspensions obtenues par ce procede |
US4542019A (en) * | 1983-03-11 | 1985-09-17 | John Lezdey | Antacid compositions |
US4744989A (en) * | 1984-02-08 | 1988-05-17 | E. R. Squibb & Sons, Inc. | Method of preparing liposomes and products produced thereby |
US4830858A (en) | 1985-02-11 | 1989-05-16 | E. R. Squibb & Sons, Inc. | Spray-drying method for preparing liposomes and products produced thereby |
IT1203515B (it) * | 1987-02-26 | 1989-02-15 | Indena Spa | Complessi di saponine con fosfolipidi e composizioni farmaceutiche e cosmetiche che li contengono |
GB8714652D0 (en) * | 1987-06-23 | 1987-07-29 | Davis S S | Drug emulsion |
US4963362A (en) | 1987-08-07 | 1990-10-16 | Regents Of The University Of Minnesota | Freeze-dried liposome mixture containing cyclosporin |
FR2619505B1 (fr) * | 1987-08-20 | 1990-08-31 | Dior Christian Parfums | Composition a base de phases lamellaires lipidiques hydratees ou de liposomes contenant de la pregnenolone ou un ester de pregnenolone, et composition cosmetique ou pharmaceutique, notamment dermatologique, a activite regeneratrice ou revitalisante, l'incorporant |
US5202126A (en) | 1987-08-20 | 1993-04-13 | Parfums Christian Dior | Composition containing pregnenolone or a pregnenolone ester incorporated in liposomes, and a method for regenerating, or revitalizing the skin therewith |
FR2623716B1 (fr) * | 1987-11-27 | 1991-04-05 | Lvmh Rech | Composition a base de phases lamellaires lipidiques hydratees ou de liposomes contenant de la tyrosine ou un derive de tyrosine et composition cosmetique ou pharmaceutique, notamment dermatologique, a activite pigmentante, l'incorporant |
US5290562A (en) | 1987-11-27 | 1994-03-01 | L V M H Recherche | Compositions and methods employing liposomes including tyrosine or a tyrosine derivative |
US5139803A (en) | 1989-02-09 | 1992-08-18 | Nabisco, Inc. | Method and liposome composition for the stabilization of oxidizable substances |
CA2150463A1 (en) * | 1992-12-02 | 1994-06-09 | Donald F. H. Wallach | Extended duration antacid product |
US5415869A (en) * | 1993-11-12 | 1995-05-16 | The Research Foundation Of State University Of New York | Taxol formulation |
FI107015B (fi) | 1996-08-09 | 2001-05-31 | Raisio Benecol Oy | Kasvistanolirasvahappoestereiden seos ja sen käyttö sekä elintarvike |
EP0927025A4 (en) * | 1996-09-18 | 2001-07-25 | Dragoco Inc | DRY POWDER COMPOSITION WITH ACTIVE INGREDIENT ENCLOSED IN LIPOSOMES |
KR19980030438A (ko) * | 1996-10-29 | 1998-07-25 | 김영환 | 반도체 버어니어 구조 및 그것을 이용한 오버레이 정확도 측정방법 |
US6312703B1 (en) | 1998-02-06 | 2001-11-06 | Lecigel, Llc | Compressed lecithin preparations |
US6110502A (en) | 1998-02-19 | 2000-08-29 | Mcneil-Ppc, Inc. | Method for producing water dispersible sterol formulations |
US6087353A (en) * | 1998-05-15 | 2000-07-11 | Forbes Medi-Tech Inc. | Phytosterol compositions and use thereof in foods, beverages, pharmaceuticals, nutraceuticals and the like |
US6063776A (en) * | 1998-05-26 | 2000-05-16 | Washington University | Sitostanol formulation with emulsifier to reduce cholesterol absorption and method for preparing and use of same |
US5932562A (en) | 1998-05-26 | 1999-08-03 | Washington University | Sitostanol formulation to reduce cholesterol absorption and method for preparing and use of same |
US6242001B1 (en) | 1998-11-30 | 2001-06-05 | Mcneil-Ppc, Inc. | Method for producing dispersible sterol and stanol compounds |
TWI290473B (en) * | 2000-05-10 | 2007-12-01 | Alliance Pharma | Phospholipid-based powders for drug delivery |
US20030129253A1 (en) * | 2002-01-03 | 2003-07-10 | Milley Christopher J. | Stable aqueous suspension |
US20030212046A1 (en) * | 2002-05-07 | 2003-11-13 | Kapac, Llc | Methods and formulations for enhancing the absorption and gastro-intestinal bioavailability of hydrophobic drugs |
US20060093661A1 (en) | 2002-05-07 | 2006-05-04 | Kapac, Llc | Methods and formulations for enhancing the absorption and gastro-intestinal bioavailability of hydrophobic drugs |
DK1830814T3 (da) * | 2005-01-06 | 2009-08-03 | Cima Labs Inc | Smagsmaskeret formulering til ikke-plastificerende lægemidler |
KR101430767B1 (ko) * | 2005-07-18 | 2014-08-19 | 유니버시티 오브 메사츄세츠 로웰 | 나노에멀젼 조성물 및 이의 제조 및 사용 방법 |
-
2006
- 2006-11-27 US US11/563,356 patent/US20080124387A1/en not_active Abandoned
-
2007
- 2007-11-23 CA CA2612128A patent/CA2612128C/en not_active Expired - Fee Related
- 2007-11-26 MX MX2007014830A patent/MX2007014830A/es not_active Application Discontinuation
- 2007-11-26 EP EP07254580.9A patent/EP1925294B1/en active Active
- 2007-11-26 ES ES07254580.9T patent/ES2535076T3/es active Active
- 2007-11-27 JP JP2007305756A patent/JP5225663B2/ja not_active Expired - Fee Related
- 2007-11-27 BR BRPI0704205-1A patent/BRPI0704205A2/pt not_active Application Discontinuation
-
2008
- 2008-08-06 AU AU2008203553A patent/AU2008203553B2/en not_active Ceased
-
2011
- 2011-01-20 US US13/010,612 patent/US20110111009A1/en not_active Abandoned
-
2014
- 2014-08-06 US US14/452,958 patent/US20150030671A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
BRPI0704205A2 (pt) | 2010-09-08 |
AU2008203553A1 (en) | 2008-10-23 |
AU2008203553B2 (en) | 2010-10-28 |
CA2612128C (en) | 2012-01-31 |
CA2612128A1 (en) | 2008-05-27 |
EP1925294B1 (en) | 2015-04-08 |
JP5225663B2 (ja) | 2013-07-03 |
US20110111009A1 (en) | 2011-05-12 |
EP1925294A1 (en) | 2008-05-28 |
JP2008133281A (ja) | 2008-06-12 |
US20080124387A1 (en) | 2008-05-29 |
US20150030671A1 (en) | 2015-01-29 |
ES2535076T3 (es) | 2015-05-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC | Refusal |