MX2007009985A - Diastereoisomeros de 4-hidroxiisoleucina y usos de los mismos. - Google Patents

Diastereoisomeros de 4-hidroxiisoleucina y usos de los mismos.

Info

Publication number
MX2007009985A
MX2007009985A MX2007009985A MX2007009985A MX2007009985A MX 2007009985 A MX2007009985 A MX 2007009985A MX 2007009985 A MX2007009985 A MX 2007009985A MX 2007009985 A MX2007009985 A MX 2007009985A MX 2007009985 A MX2007009985 A MX 2007009985A
Authority
MX
Mexico
Prior art keywords
hydroxyisoleucine
diabetes
type
isomers
diastereoisomers
Prior art date
Application number
MX2007009985A
Other languages
English (en)
Spanish (es)
Inventor
Charles Mioskowski
Alain Wagner
Claude Coquelet
Original Assignee
Innodia Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Innodia Inc filed Critical Innodia Inc
Publication of MX2007009985A publication Critical patent/MX2007009985A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32Oxygen atoms
    • C07D307/33Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
MX2007009985A 2005-02-18 2006-02-17 Diastereoisomeros de 4-hidroxiisoleucina y usos de los mismos. MX2007009985A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65441305P 2005-02-18 2005-02-18
PCT/IB2006/001758 WO2006117696A2 (en) 2005-02-18 2006-02-17 Diastereoisomers of 4-hydroxyisoleucine and uses thereof

Publications (1)

Publication Number Publication Date
MX2007009985A true MX2007009985A (es) 2008-03-11

Family

ID=37086084

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007009985A MX2007009985A (es) 2005-02-18 2006-02-17 Diastereoisomeros de 4-hidroxiisoleucina y usos de los mismos.

Country Status (8)

Country Link
EP (1) EP1853552A2 (ja)
JP (1) JP2008530198A (ja)
CN (1) CN101128418A (ja)
AU (1) AU2006242851A1 (ja)
BR (1) BRPI0607140A2 (ja)
CA (1) CA2598491A1 (ja)
MX (1) MX2007009985A (ja)
WO (1) WO2006117696A2 (ja)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006131836A2 (en) * 2005-03-22 2006-12-14 Innodia Inc. Compounds and compositions for use in the prevention and treatment of obesity and related syndromes
WO2008154743A1 (en) * 2007-06-19 2008-12-24 Innodia Inc. Methods for the synthesis of 4-hydroxyisoleucine, stereoisomers and analogs thereof
US20110136911A1 (en) * 2007-12-20 2011-06-09 The Feinstein Institute For Medical Research Treatment of sepsis and inhibition of mif by d-t4
JP6800968B2 (ja) 2015-10-23 2020-12-16 ナビター ファーマシューティカルズ, インコーポレイテッド セストリン−gator2相互作用のモジュレーターおよびその使用
JP7179015B2 (ja) 2017-04-26 2022-11-28 ナビター ファーマシューティカルズ, インコーポレイテッド Sestrin-GATOR2相互座用のモジュレーターおよびその使用
EP3870158A4 (en) 2018-10-24 2022-08-10 Navitor Pharmaceuticals, Inc. POLYMORPHIC COMPOUNDS AND USES THEREOF
AU2020376950A1 (en) 2019-11-01 2022-06-09 Navitor Pharmaceuticals, Inc. Methods of treatment using an mTORC1 modulator
CN112089710B (zh) * 2020-08-07 2022-04-01 郑州大学 4-羟基异亮氨酸在制备抗肿瘤药物中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2797767B1 (fr) * 1999-08-27 2002-06-14 Centre Nat Rech Scient Utilisation d'acides amines pour la fabrication de medicaments destines au traitement des insulino-resistances
BRPI0415781A (pt) * 2003-10-27 2006-12-26 Innodia Inc método para o tratamento de diabetes em um paciente e kit farmacêutico
EP1657236A1 (en) * 2004-11-10 2006-05-17 Centre National De La Recherche Scientifique (Cnrs) Method for preparing diastereoisomers of 4-hydroxy isoleucine

Also Published As

Publication number Publication date
BRPI0607140A2 (pt) 2009-08-11
JP2008530198A (ja) 2008-08-07
WO2006117696A2 (en) 2006-11-09
CA2598491A1 (en) 2006-11-09
EP1853552A2 (en) 2007-11-14
AU2006242851A1 (en) 2006-11-09
WO2006117696A3 (en) 2007-01-25
CN101128418A (zh) 2008-02-20

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal