MX2007009961A - Composicion adyuvante que comprende fosfato de aluminio y 3d-mpl. - Google Patents

Composicion adyuvante que comprende fosfato de aluminio y 3d-mpl.

Info

Publication number
MX2007009961A
MX2007009961A MX2007009961A MX2007009961A MX2007009961A MX 2007009961 A MX2007009961 A MX 2007009961A MX 2007009961 A MX2007009961 A MX 2007009961A MX 2007009961 A MX2007009961 A MX 2007009961A MX 2007009961 A MX2007009961 A MX 2007009961A
Authority
MX
Mexico
Prior art keywords
adjuvant
mpl
adjuvant composition
aluminium phosphate
iii
Prior art date
Application number
MX2007009961A
Other languages
English (en)
Inventor
Derek O'hagan
Original Assignee
Novartis Vaccines & Diagnostic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Vaccines & Diagnostic filed Critical Novartis Vaccines & Diagnostic
Publication of MX2007009961A publication Critical patent/MX2007009961A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

Se proporciona una composicion inmunogenica que comprende: (i) un antigeno; (ii) un adyuvante de fosfato de aluminio; y (iii) un adyuvante de monofosforilo lipido A 3-O-desacilado. Los componentes (ii) y (iii) tambien puede ser utilizado como un sistema adyuvante separado. Se presentan diversos rasgos de las composiciones que incluyen por lo menos 50% del adyuvante de monofosforilo lipido A 3-O-desacilado deber ser adsorbido en el adyuvante de fosfato de aluminio. La mezcla adyuvante es particularmente util con el antigeno de superficie del virus de hepatitis B.
MX2007009961A 2005-02-16 2006-02-16 Composicion adyuvante que comprende fosfato de aluminio y 3d-mpl. MX2007009961A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65374105P 2005-02-16 2005-02-16
PCT/GB2006/000557 WO2006087563A2 (en) 2005-02-16 2006-02-16 Adjuvant composition comprising aluminium phosphate and 3d-mpl

Publications (1)

Publication Number Publication Date
MX2007009961A true MX2007009961A (es) 2008-01-29

Family

ID=36916823

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007009961A MX2007009961A (es) 2005-02-16 2006-02-16 Composicion adyuvante que comprende fosfato de aluminio y 3d-mpl.

Country Status (18)

Country Link
US (1) US20090214592A1 (es)
EP (1) EP1850871A2 (es)
JP (1) JP2008530195A (es)
KR (1) KR20070110513A (es)
CN (1) CN101146551A (es)
AP (1) AP2007004151A0 (es)
AU (1) AU2006215419B2 (es)
BE (1) BE1016991A6 (es)
BR (1) BRPI0608430A2 (es)
CA (1) CA2598079A1 (es)
EA (1) EA012212B1 (es)
IL (1) IL185346A0 (es)
MX (1) MX2007009961A (es)
NO (1) NO20074679L (es)
NZ (1) NZ560930A (es)
SG (1) SG160328A1 (es)
WO (1) WO2006087563A2 (es)
ZA (1) ZA200707089B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ565512A (en) * 2005-08-02 2011-08-26 Novartis Vaccines & Diagnostic Reducing interference between oil-containing adjuvants and surfactant-containing antigens
EP1862176A1 (de) * 2006-05-31 2007-12-05 Rhein Biotech Gesellschaft für neue biotechnologische Prozesse und Produkte mbH Ein Verfahren zur Herstellung einer Impfzusammensetzung
EP1862177A1 (de) * 2006-06-01 2007-12-05 Rhein Biotech Gesellschaft für neue biotechnologische Prozesse und Produkte mbH Ein Verfahren zur Herstellung einer Impfzusammensetzung
CA2662051A1 (en) * 2006-09-07 2008-03-13 Glaxosmithkline Biologicals S.A. Vaccine
NO2403507T3 (es) 2009-03-05 2018-07-21
CN102526724B (zh) * 2011-01-14 2015-07-22 四川大学 氢氧化铝凝胶-多糖复合免疫佐剂及其制备方法和用途
JP6109165B2 (ja) * 2011-07-01 2017-04-05 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア ヘルペスウイルスワクチンおよび使用方法
CN103330936B (zh) * 2013-07-18 2016-01-27 北京民海生物科技有限公司 一种磷酸铝佐剂原位法制备乙肝疫苗的方法
AU2014388299A1 (en) * 2014-03-25 2016-10-20 The Government Of The United States Of America As Represented By The Secretary Of The Army Methods for enhancing the immunostimulation potency of aluminum salt-adsorbed vaccines

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4707542A (en) * 1983-08-22 1987-11-17 Merck & Co., Inc. Immunogenic HbsAg derived from transformed yeast
GB8508685D0 (en) * 1985-04-03 1985-05-09 Minor P D Peptides
US4912094B1 (en) * 1988-06-29 1994-02-15 Ribi Immunochem Research Inc. Modified lipopolysaccharides and process of preparation
US5084282A (en) * 1990-08-16 1992-01-28 J.C. Steele & Sons Apparatus for forming bricks having a textured edge
EP0515704B1 (de) * 1991-04-26 1993-01-20 Hans Lingl Anlagenbau und Verfahrenstechnik GmbH & Co. KG Verfahren und Vorrichtung zum Kerben eines Tonstrangstückes
US6620414B2 (en) * 1992-03-27 2003-09-16 Smithkline Beecham Biologicals (S.A.) Hepatitis vaccines containing 3-0-deacylated monophoshoryl lipid A
JP4028593B2 (ja) * 1993-03-23 2007-12-26 グラクソスミスクライン・バイオロジカルス・ソシエテ・アノニム ３−ｏ脱アシル化モノホスホリルリピドａ含有ワクチン組成物
GB9503863D0 (en) * 1995-02-25 1995-04-19 Smithkline Beecham Biolog Vaccine compositions
US6488934B1 (en) * 1995-02-25 2002-12-03 Smithkline Beecham Biologicals S.A. Hepatitis B vaccine
US20010053365A1 (en) * 1995-04-25 2001-12-20 Smithkline Beecham Biologicals S.A. Vaccines
GB9718901D0 (en) * 1997-09-05 1997-11-12 Smithkline Beecham Biolog Vaccine
HU228473B1 (en) * 1998-10-16 2013-03-28 Smithkline Beecham Biolog Adjuvant systems and vaccines
GB9822714D0 (en) * 1998-10-16 1998-12-09 Smithkline Beecham Sa Vaccines
GB9921146D0 (en) * 1999-09-07 1999-11-10 Smithkline Beecham Biolog Novel composition
US7030094B2 (en) * 2002-02-04 2006-04-18 Corixa Corporation Immunostimulant compositions comprising an aminoalkyl glucosaminide phosphate and QS-21

Also Published As

Publication number Publication date
ZA200707089B (en) 2008-11-26
AP2007004151A0 (en) 2007-10-31
WO2006087563A2 (en) 2006-08-24
IL185346A0 (en) 2008-02-09
AU2006215419B2 (en) 2012-03-08
WO2006087563A3 (en) 2007-03-15
KR20070110513A (ko) 2007-11-19
CA2598079A1 (en) 2006-08-24
AU2006215419A1 (en) 2006-08-24
EA200701743A1 (ru) 2008-02-28
JP2008530195A (ja) 2008-08-07
EP1850871A2 (en) 2007-11-07
NZ560930A (en) 2011-06-30
BRPI0608430A2 (pt) 2009-12-29
CN101146551A (zh) 2008-03-19
SG160328A1 (en) 2010-04-29
US20090214592A1 (en) 2009-08-27
NO20074679L (no) 2007-09-13
EA012212B1 (ru) 2009-08-28
BE1016991A6 (fr) 2007-11-06

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