MX2007004427A - Intermedio de rosuvastatina cristalina. - Google Patents

Intermedio de rosuvastatina cristalina.

Info

Publication number
MX2007004427A
MX2007004427A MX2007004427A MX2007004427A MX2007004427A MX 2007004427 A MX2007004427 A MX 2007004427A MX 2007004427 A MX2007004427 A MX 2007004427A MX 2007004427 A MX2007004427 A MX 2007004427A MX 2007004427 A MX2007004427 A MX 2007004427A
Authority
MX
Mexico
Prior art keywords
crystalline rosuvastatin
rosuvastatin intermediate
crystalline
processes
preparation
Prior art date
Application number
MX2007004427A
Other languages
English (en)
Inventor
Valerie Niddam-Hildesheim
Natalia Shenkar
Shlomit Wizel
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teva Pharma filed Critical Teva Pharma
Publication of MX2007004427A publication Critical patent/MX2007004427A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Abstract

Se proporciona un intermedio de rosuvastatina cristalina y procesos para la preparacion del mismo.
MX2007004427A 2005-08-16 2006-08-16 Intermedio de rosuvastatina cristalina. MX2007004427A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70892005P 2005-08-16 2005-08-16
US71093005P 2005-08-23 2005-08-23
PCT/US2006/032539 WO2007022488A2 (en) 2005-08-16 2006-08-16 Crystalline rosuvastatin intermediate

Publications (1)

Publication Number Publication Date
MX2007004427A true MX2007004427A (es) 2007-06-14

Family

ID=37671343

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007004427A MX2007004427A (es) 2005-08-16 2006-08-16 Intermedio de rosuvastatina cristalina.

Country Status (10)

Country Link
US (1) US7868169B2 (es)
EP (1) EP1805148A2 (es)
JP (1) JP2008515931A (es)
KR (1) KR20070062996A (es)
BR (1) BRPI0605917A2 (es)
CA (1) CA2619576C (es)
IL (1) IL186221A (es)
MX (1) MX2007004427A (es)
TW (1) TW200800917A (es)
WO (1) WO2007022488A2 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070167625A1 (en) * 2005-02-22 2007-07-19 Anna Balanov Preparation of rosuvastatin
WO2007022488A2 (en) 2005-08-16 2007-02-22 Teva Pharmaceutical Industries Ltd. Crystalline rosuvastatin intermediate
US8653265B2 (en) 2008-05-27 2014-02-18 Changzhou Pharmaceutical Factory Preparation method of rosuvastatin calcium and its intermediates
IT1397912B1 (it) * 2010-01-28 2013-02-04 Chemi Spa Nuovo polimorfo dell'estere 6-dietilamminometil-2-naftilico dell'acido 4-idrossicarbamoil-fenil-carbammico cloridrato.
CA2832343A1 (en) 2011-04-18 2012-10-26 Basf Se Multicomponent crystalline system of rosuvastatin calcium salt and vanillin

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KR100511533B1 (ko) * 2002-04-09 2005-08-31 임광민 키랄 중간체, 그의 제조방법 및 그를 이용한 HMG-CoA환원저해제의 제조방법
BR0311195A (pt) 2002-05-21 2005-02-22 Ranbaxy Lab Ltd Processo de preparação de rosuvastatina
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GB0312896D0 (en) 2003-06-05 2003-07-09 Astrazeneca Ab Chemical process
WO2005021511A1 (en) 2003-08-27 2005-03-10 Hetero Drugs Limited A novel process for amorphous rosuvastatin calcium
EP1562912A2 (en) 2003-08-28 2005-08-17 Teva Pharmaceutical Industries Limited Process for preparation of rosuvastatin calcium
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WO2005054207A1 (en) 2003-12-04 2005-06-16 Glenmark Pharmaceuticals Limited Process for the preparation of pyrimidine derivatives
US20050159615A1 (en) 2003-12-24 2005-07-21 Entire Interest. Process for preparation of statins with high syn to anti ratio
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CN1807417A (zh) 2005-01-18 2006-07-26 何如钧 新型无水无结晶型态的罗伐他汀钙盐
WO2006079611A1 (en) 2005-01-31 2006-08-03 Ciba Specialty Chemicals Holding Inc. Crystalline forms of rosuvastatin calcium salt
US20070037979A1 (en) * 2005-02-22 2007-02-15 Valerie Niddam-Hildesheim Preparation of rosuvastatin
US20070167625A1 (en) 2005-02-22 2007-07-19 Anna Balanov Preparation of rosuvastatin
US20090124803A1 (en) 2005-03-22 2009-05-14 Pandurang Balwant Deshpande Process for preparation of rosuvastatin
WO2006106526A1 (en) 2005-04-04 2006-10-12 Unichem Laboratories Limited Process for preparation of calcium salt of rosuvastatin
CN1872841A (zh) 2005-06-01 2006-12-06 信谊药厂 瑞舒伐他汀钙及其关键中间体的制备方法
US9150518B2 (en) 2005-06-24 2015-10-06 Lek Pharmaceuticals, D.D. Process for preparing amorphous rosuvastatin calcium of impurities
ES2564807T5 (es) 2005-06-24 2019-02-26 Lek Pharmaceuticals Proceso para preparación de rosuvastatina de calcio amorfa pura
GB0514078D0 (en) 2005-07-08 2005-08-17 Astrazeneca Uk Ltd Chemical process
WO2007022488A2 (en) 2005-08-16 2007-02-22 Teva Pharmaceutical Industries Ltd. Crystalline rosuvastatin intermediate
CN100352821C (zh) 2005-08-22 2007-12-05 鲁南制药集团股份有限公司 一种瑞舒伐他汀钙中间体的制备方法

Also Published As

Publication number Publication date
TW200800917A (en) 2008-01-01
WO2007022488A3 (en) 2007-05-03
EP1805148A2 (en) 2007-07-11
IL186221A0 (en) 2008-01-20
IL186221A (en) 2011-11-30
WO2007022488A2 (en) 2007-02-22
US20070123550A1 (en) 2007-05-31
CA2619576A1 (en) 2007-02-22
CA2619576C (en) 2011-12-06
JP2008515931A (ja) 2008-05-15
US7868169B2 (en) 2011-01-11
BRPI0605917A2 (pt) 2009-05-26
KR20070062996A (ko) 2007-06-18

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Legal Events

Date Code Title Description
FA Abandonment or withdrawal