MX2007003167A - Asministracion de polinucleotidos. - Google Patents
Asministracion de polinucleotidos.Info
- Publication number
- MX2007003167A MX2007003167A MX2007003167A MX2007003167A MX2007003167A MX 2007003167 A MX2007003167 A MX 2007003167A MX 2007003167 A MX2007003167 A MX 2007003167A MX 2007003167 A MX2007003167 A MX 2007003167A MX 2007003167 A MX2007003167 A MX 2007003167A
- Authority
- MX
- Mexico
- Prior art keywords
- polynucleotides
- delivery
- formulations
- present
- methods
- Prior art date
Links
- 102000040430 polynucleotide Human genes 0.000 title 1
- 108091033319 polynucleotide Proteins 0.000 title 1
- 239000002157 polynucleotide Substances 0.000 title 1
- 238000009472 formulation Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000012528 membrane Substances 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/111—General methods applicable to biologically active non-coding nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/13—Decoys
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/31—Chemical structure of the backbone
- C12N2310/315—Phosphorothioates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/35—Nature of the modification
- C12N2310/351—Conjugate
- C12N2310/3513—Protein; Peptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
- C12N2320/32—Special delivery means, e.g. tissue-specific
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61204604P | 2004-09-21 | 2004-09-21 | |
| US66349705P | 2005-03-18 | 2005-03-18 | |
| PCT/US2005/034110 WO2006034433A2 (en) | 2004-09-21 | 2005-09-21 | Delivery of polynucleotides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2007003167A true MX2007003167A (es) | 2007-05-16 |
Family
ID=36090693
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2007003167A MX2007003167A (es) | 2004-09-21 | 2005-09-21 | Asministracion de polinucleotidos. |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20060069055A1 (enExample) |
| EP (1) | EP1799271A4 (enExample) |
| JP (1) | JP2008513513A (enExample) |
| AU (1) | AU2005286640A1 (enExample) |
| CA (1) | CA2583413A1 (enExample) |
| MX (1) | MX2007003167A (enExample) |
| WO (1) | WO2006034433A2 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005056795A2 (en) * | 2003-12-03 | 2005-06-23 | Corgentech, Inc. | Hif oligonucleotide decoy molecules |
| KR20070044805A (ko) * | 2004-04-15 | 2007-04-30 | 키아스마, 인코포레이티드 | 생물학적 장벽 투과를 촉진시킬 수 있는 조성물 |
| US20070219131A1 (en) * | 2004-04-15 | 2007-09-20 | Ben-Sasson Shmuel A | Compositions capable of facilitating penetration across a biological barrier |
| US9486408B2 (en) | 2005-12-01 | 2016-11-08 | University Of Massachusetts Lowell | Botulinum nanoemulsions |
| US8530436B2 (en) * | 2007-01-29 | 2013-09-10 | Transderm, Inc. | Methods and compositions for transdermal delivery of nucleotides |
| WO2008113017A2 (en) * | 2007-03-14 | 2008-09-18 | Sierra Molecular Corporation | Compositions, systems, and methods for preservation and/or stabilization of a cell and/or macromolecule |
| DK2158316T3 (en) * | 2007-05-11 | 2015-07-20 | Adynxx Inc | Gene expression and pain |
| JP5294302B2 (ja) * | 2008-03-28 | 2013-09-18 | マルホ株式会社 | 胸腺間質リンパ球増殖因子産生を評価するスクリーニング方法 |
| JP5623406B2 (ja) | 2008-09-17 | 2014-11-12 | キアズマ インコーポレイテッド | 医薬組成物および関連する送達方法 |
| IL293156A (en) * | 2011-01-24 | 2022-07-01 | Anterios Inc | Nanoparticle compounds, their formulations, and their use |
| AU2013243949A1 (en) * | 2012-04-02 | 2014-10-30 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of biologics and proteins associated with human disease |
| US10501513B2 (en) | 2012-04-02 | 2019-12-10 | Modernatx, Inc. | Modified polynucleotides for the production of oncology-related proteins and peptides |
| US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
| AU2013243954A1 (en) | 2012-04-02 | 2014-10-30 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of cosmetic proteins and peptides |
| US9254311B2 (en) | 2012-04-02 | 2016-02-09 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of proteins |
| RU2668136C2 (ru) | 2012-05-10 | 2018-09-26 | Эйдинкс, Инк. | Композиции для доставки активных ингредиентов |
| JP6705807B2 (ja) | 2014-08-15 | 2020-06-03 | エーダイニクス インコーポレイテッド | 疼痛を治療するためのオリゴヌクレオチドデコイ |
| EP3253401B1 (en) | 2015-02-03 | 2025-04-02 | Amryt Endo, Inc. | Treating acromegaly with oral octreotide |
| KR102487144B1 (ko) | 2016-11-21 | 2023-01-12 | 에이리온 테라퓨틱스, 인코포레이티드 | 큰 물질의 경피 전달 |
| ES2975176T3 (es) * | 2017-03-23 | 2024-07-03 | Lipid Systems Sp Z O O | Encapsulación de alta eficiencia de compuestos hidrófilos en liposomas unilamelares |
| WO2018227129A1 (en) * | 2017-06-09 | 2018-12-13 | Regents Of The University Of Minnesota | Skin care formulations and skin cancer treatment |
| US11141457B1 (en) | 2020-12-28 | 2021-10-12 | Amryt Endo, Inc. | Oral octreotide therapy and contraceptive methods |
| CN114469897B (zh) * | 2022-01-12 | 2023-02-28 | 上海市胸科医院 | 靶向治疗心肌梗死的锂皂石复合递送材料及其制备与应用 |
| US20230406888A1 (en) * | 2022-04-27 | 2023-12-21 | Sachi Bioworks Inc. | Methods and systems for targeting autoimmune and inflammatory pathways using nanoligomers |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6410516B1 (en) * | 1986-01-09 | 2002-06-25 | President & Fellows Of Harvard College | Nuclear factors associated with transcriptional regulation |
| US6262022B1 (en) * | 1992-06-25 | 2001-07-17 | Novartis Ag | Pharmaceutical compositions containing cyclosporin as the active agent |
| US6699985B2 (en) * | 1991-08-21 | 2004-03-02 | Arsinur Burcoglu | Method of treating HIV infection and related secondary infections thereof |
| US6399376B1 (en) * | 1993-11-05 | 2002-06-04 | Isis Pharmaceuticals, Inc. | Modulation of vascular cell adhesive molecule expression through oligonucleotide interactions |
| ATE357922T1 (de) * | 1995-05-12 | 2007-04-15 | Anges Mg Inc | Heilung und vorbeugung von durch nf-kappab verursachten erkrankungen |
| AU731909B2 (en) * | 1997-07-01 | 2001-04-05 | Isis Pharmaceuticals, Inc. | Compositions and methods for the delivery of oligonucleotides via the alimentary canal |
| JP4215219B2 (ja) * | 1997-07-04 | 2009-01-28 | アンジェスＭｇ株式会社 | 脳保護剤 |
| JP2002515514A (ja) * | 1998-05-21 | 2002-05-28 | アイシス・ファーマシューティカルス・インコーポレーテッド | オリゴヌクレオチドの局所送逹のための組成物及び方法 |
| AU745880B2 (en) * | 1998-05-21 | 2002-04-11 | Isis Pharmaceuticals, Inc. | Compositions and methods for non-parenteral delivery of oligonucleotides |
| US20030206958A1 (en) * | 2000-12-22 | 2003-11-06 | Cattaneo Maurizio V. | Chitosan biopolymer for the topical delivery of active agents |
| US6187587B1 (en) * | 2000-03-02 | 2001-02-13 | Isis Pharmaceuticals, Inc. | Antisense inhibition of e2f transcription factor 1 expression |
| US20050203612A1 (en) * | 2000-12-22 | 2005-09-15 | Avantec Vascular Corporation | Devices delivering therapeutic agents and methods regarding the same |
| JP4346233B2 (ja) * | 2000-12-27 | 2009-10-21 | アンジェスＭｇ株式会社 | デコイを含む薬学的組成物およびその使用方法 |
| PT1362600E (pt) * | 2001-02-20 | 2008-07-09 | Anges Mg Inc | Utilização tópica de iscos de nf-kb para o tratamento da dermatite atópica |
| CN1615157A (zh) * | 2001-11-22 | 2005-05-11 | 安琪士多摩奇株式会社 | 抑制器官移植排异反应的组合物及其使用方法 |
| JPWO2003063911A1 (ja) * | 2002-02-01 | 2006-01-19 | アンジェスＭｇ株式会社 | デコイを含む薬学的組成物およびその使用方法 |
| US20060135449A1 (en) * | 2002-03-29 | 2006-06-22 | Yoshiki Sawa | Decoy compositions for treating and preventing brain diseases and disorders |
| HUE037352T2 (hu) * | 2002-04-05 | 2018-08-28 | Roche Innovation Ct Copenhagen As | A HIF-1alfa expresszálódását módosító oligomer vegyületek |
| CA2493902A1 (en) * | 2002-05-29 | 2003-12-04 | Anges Mg, Inc. | Decoy composition for treating and preventing inflammatory disease |
| WO2004060317A2 (en) * | 2002-12-31 | 2004-07-22 | Genta Incorporated | Combination of gallium compounds with nonchemotherapeutic anticancer agents in the treatment of neoplasia |
| US20040191779A1 (en) * | 2003-03-28 | 2004-09-30 | Jie Zhang | Statistical analysis of regulatory factor binding sites of differentially expressed genes |
| EP1462111A1 (en) * | 2003-03-28 | 2004-09-29 | Universiteit Utrecht Holding B.V. | Composition for inducing immunotolerance |
| WO2005051229A2 (en) * | 2003-11-24 | 2005-06-09 | Avantec Vascular Corporation | Devices delivering therapeutic agents and methods regarding the same |
| US7378509B2 (en) * | 2003-12-02 | 2008-05-27 | Anesiva, Inc. | NF-kappaB oligonucleotide decoy molecules |
| WO2005056795A2 (en) * | 2003-12-03 | 2005-06-23 | Corgentech, Inc. | Hif oligonucleotide decoy molecules |
| US7585848B2 (en) * | 2005-01-11 | 2009-09-08 | Rush University Medical Center | Methods and compositions for treating, inhibiting and reversing disorders of the intervertebral disc |
| US20060258604A1 (en) * | 2005-05-10 | 2006-11-16 | Warren Strober | Compositions and methods for the treatment of inflammatory bowel disease utilizing NF-kappaB decoy polynucleotides |
-
2005
- 2005-09-21 EP EP05800264A patent/EP1799271A4/en not_active Withdrawn
- 2005-09-21 AU AU2005286640A patent/AU2005286640A1/en not_active Abandoned
- 2005-09-21 MX MX2007003167A patent/MX2007003167A/es not_active Application Discontinuation
- 2005-09-21 US US11/233,511 patent/US20060069055A1/en not_active Abandoned
- 2005-09-21 CA CA002583413A patent/CA2583413A1/en not_active Abandoned
- 2005-09-21 JP JP2007532679A patent/JP2008513513A/ja active Pending
- 2005-09-21 WO PCT/US2005/034110 patent/WO2006034433A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| CA2583413A1 (en) | 2006-03-30 |
| AU2005286640A1 (en) | 2006-03-30 |
| US20060069055A1 (en) | 2006-03-30 |
| EP1799271A4 (en) | 2010-05-05 |
| WO2006034433A2 (en) | 2006-03-30 |
| JP2008513513A (ja) | 2008-05-01 |
| EP1799271A2 (en) | 2007-06-27 |
| WO2006034433A3 (en) | 2007-03-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2007003167A (es) | Asministracion de polinucleotidos. | |
| WO2007039319A3 (en) | Dna microarray for rapid identification of candida albicans in blood cultures | |
| WO2006029258A3 (en) | Aptamer medicinal chemistry | |
| WO2005079363A3 (en) | Aptamer therapeutics useful in the treatment of complement-related disorders | |
| WO2005059097A3 (en) | Methods for high fidelity production of long nucleic acid molecules | |
| WO2004024757A3 (en) | Modified pna molecules | |
| WO2008069906A3 (en) | Digital expression of gene analysis | |
| WO2006088888A3 (en) | Aptamer therapeutics useful in the treatment of complement-related disorders | |
| WO2006066048A3 (en) | Compositions for bacterial mediated gene silencing and methods of using same | |
| WO2010042891A3 (en) | Method for inducing pluripotency in cells | |
| EP2508614A3 (en) | Glycosylation of molecules | |
| WO2006048777A3 (en) | Modified growth hormones | |
| IL190796A (en) | Composition containing nucleic acid encoded by anti-osteoclastogenic protein | |
| EP4397760A3 (en) | Composition for cleaving a target dna comprising a guide rna specific for the target dna and cas protein-encoding nucleic acid or cas protein, and use thereof | |
| IN2015DN00255A (enExample) | ||
| WO2006135684A3 (en) | Methods and kits for sense rna synthesis | |
| ATE502122T1 (de) | Chemisch modifizierte oligonukleotidprimer zur nukleinsäureamplifikation | |
| WO2006099164A3 (en) | Methods for multiplex amplification | |
| CL2007001553A1 (es) | Proceso para una mejor asimilacion, acumulacion y/o utilizacion de nitrogeno y/o para un aumento del contenido total de nitrogeno en un organismo activo fotosintetico; moleculas de acidos nucleicos aisladas; construccion, vector y celula huesped que | |
| WO2010039802A3 (en) | Methods and compositions for isolating nucleic acid | |
| WO2009108217A3 (en) | Compositions comprising k-ras sirna and methods of use | |
| WO2009013461A8 (en) | Growth hormone fusion proteins | |
| ZA200700456B (en) | Nucleic acid molecules and their use in plant male sterility | |
| EP2520658A3 (en) | Enhancing spinosyn production with oxygen binding proteins | |
| WO2009143371A3 (en) | COMPOSITIONS COMPRISING mTOR SIRNA AND METHODS OF USE THEREOF |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA | Abandonment or withdrawal |