MX2007001292A - Metodo para modular la expresion genica al alterar el contendido de cpg. - Google Patents

Metodo para modular la expresion genica al alterar el contendido de cpg.

Info

Publication number
MX2007001292A
MX2007001292A MX2007001292A MX2007001292A MX2007001292A MX 2007001292 A MX2007001292 A MX 2007001292A MX 2007001292 A MX2007001292 A MX 2007001292A MX 2007001292 A MX2007001292 A MX 2007001292A MX 2007001292 A MX2007001292 A MX 2007001292A
Authority
MX
Mexico
Prior art keywords
modifying
gene expression
modulating gene
cpg content
relates
Prior art date
Application number
MX2007001292A
Other languages
English (en)
Inventor
Frank Notka
Marcus Graf
Doris Leikam
Ralf Wagner
David Raab
Original Assignee
Geneart Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35839637&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2007001292(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE200410037652 external-priority patent/DE102004037652B4/de
Priority claimed from DE102004037611A external-priority patent/DE102004037611B4/de
Application filed by Geneart Ag filed Critical Geneart Ag
Publication of MX2007001292A publication Critical patent/MX2007001292A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43595—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from coelenteratae, e.g. medusae
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/46—Vector systems having a special element relevant for transcription elements influencing chromatin structure, e.g. scaffold/matrix attachment region, methylation free island
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Control Of Electric Motors In General (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Oscillators With Electromechanical Resonators (AREA)
  • Electrotherapy Devices (AREA)

Abstract

La invencion se refiere a modificaciones de acido nucleico para una modulacion de expresion dirigida por la insercion o remocion dirigida de dinucleotidos de CpG. La invencio tambien se refiere a acidos nucleidos modificados y vectores de expresion modificados.
MX2007001292A 2004-08-03 2005-08-03 Metodo para modular la expresion genica al alterar el contendido de cpg. MX2007001292A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE200410037652 DE102004037652B4 (de) 2004-08-03 2004-08-03 Verfahren zur Modulation der Genexpression durch Änderung des CpG Gehalts
DE102004037611A DE102004037611B4 (de) 2004-08-03 2004-08-03 Induzierbare Genexpression
PCT/EP2005/008423 WO2006015789A2 (de) 2004-08-03 2005-08-03 Verfahren zur modulation der genexpression durch änderung des cpg gehalts

Publications (1)

Publication Number Publication Date
MX2007001292A true MX2007001292A (es) 2007-07-04

Family

ID=35839637

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2007001292A MX2007001292A (es) 2004-08-03 2005-08-03 Metodo para modular la expresion genica al alterar el contendido de cpg.

Country Status (14)

Country Link
US (4) US8859275B2 (es)
EP (1) EP1776460B8 (es)
JP (1) JP4550115B2 (es)
KR (1) KR101222628B1 (es)
AT (1) ATE453716T1 (es)
AU (1) AU2005270430B2 (es)
BR (1) BRPI0513081A (es)
CA (1) CA2575490A1 (es)
DE (1) DE502005008794D1 (es)
DK (1) DK1776460T3 (es)
HK (1) HK1100089A1 (es)
IL (1) IL180786A (es)
MX (1) MX2007001292A (es)
WO (1) WO2006015789A2 (es)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE453716T1 (de) * 2004-08-03 2010-01-15 Geneart Ag Verfahren zur modulation der genexpression durch änderung des cpg gehalts
JP5709356B2 (ja) 2006-01-13 2015-04-30 アメリカ合衆国 哺乳動物細胞における発現のためのコドン最適化ＩＬ−１５およびＩＬ−１５Ｒ−α遺伝子
GB0606190D0 (en) 2006-03-28 2006-05-10 Isis Innovation Construct
EP2089513A1 (en) 2006-12-07 2009-08-19 Publiekrechtelijke rechtspersoon Academisch Ziekenhuis Leiden h.o.d.n. Leids Universitair Medisch Centrum Use of a varicellovirus tap-inhibitor for the induction of tumor- or virus-specific immunity against teipp
EP2703011A3 (en) 2007-05-07 2014-03-26 MedImmune, LLC Anti-icos antibodies and their use in treatment of oncology, transplantation and autoimmune disease
EP2019134A1 (en) * 2007-07-26 2009-01-28 Vision 7 GmbH Gene therapy of chronic granulomatous disease
ES2602585T3 (es) 2007-07-26 2017-02-21 Uniqure Ip B.V. Vectores de baculovirus que comprenden secuencias de codificación repetidas con sesgos de codones diferenciales
WO2010087709A1 (en) 2009-01-30 2010-08-05 Amsterdam Molecular Therapeutics (Amt) Ip B.V. Alanine-glyoxylate aminotransferase therapeutics
EP2534264A4 (en) * 2010-02-09 2014-02-26 Univ Columbia METHODS FOR MODIFYING EXPRESSION AND SOLUBILITY OF POLYPEPTIDES
EP2646795B1 (en) 2010-11-29 2019-02-20 Dako Denmark A/S Methods for analyzing images of specimens processed by a programmable quantitative assay
DE102010056289A1 (de) 2010-12-24 2012-06-28 Geneart Ag Verfahren zur Herstellung von Leseraster-korrekten Fragment-Bibliotheken
CN103907117B (zh) 2011-09-01 2019-03-29 基因组编译器公司 用于多核苷酸构建体设计的系统和方法
US20130109596A1 (en) 2011-09-26 2013-05-02 Life Technologies Corporation High efficiency, small volume nucleic acid synthesis
WO2014153188A2 (en) 2013-03-14 2014-09-25 Life Technologies Corporation High efficiency, small volume nucleic acid synthesis
US20130274129A1 (en) 2012-04-04 2013-10-17 Geneart Ag Tal-effector assembly platform, customized services, kits and assays
KR102351838B1 (ko) 2013-08-05 2022-01-18 트위스트 바이오사이언스 코포레이션 드 노보 합성된 유전자 라이브러리
EP3035960B1 (en) * 2013-08-21 2019-07-03 CureVac AG Respiratory syncytial virus (rsv) vaccine
AU2014310931B2 (en) 2013-08-21 2019-12-19 CureVac SE Rabies vaccine
KR20160042935A (ko) * 2013-08-21 2016-04-20 큐어백 아게 폐암 치료를 위한 조성물 및 백신
EP3035955B1 (en) * 2013-08-21 2019-09-11 CureVac AG Composition and vaccine for treating lung cancer
EP3035961A1 (en) * 2013-08-21 2016-06-29 CureVac AG Rabies vaccine
SG11201510746WA (en) 2013-08-21 2016-03-30 Curevac Ag Respiratory syncytial virus (rsv) vaccine
KR20160043103A (ko) * 2013-08-21 2016-04-20 큐어백 아게 전립선암 치료를 위한 조성물 및 백신
US20170362627A1 (en) * 2014-11-10 2017-12-21 Modernatx, Inc. Multiparametric nucleic acid optimization
GB201420139D0 (en) 2014-11-12 2014-12-24 Ucl Business Plc Factor IX gene therapy
WO2016094512A1 (en) 2014-12-09 2016-06-16 yLIFE TECHNOLOGIES CORPORATION High efficiency, small volume nucleic acid synthesis
US10669304B2 (en) 2015-02-04 2020-06-02 Twist Bioscience Corporation Methods and devices for de novo oligonucleic acid assembly
US9981239B2 (en) 2015-04-21 2018-05-29 Twist Bioscience Corporation Devices and methods for oligonucleic acid library synthesis
WO2016180430A1 (en) 2015-05-08 2016-11-17 Curevac Ag Method for producing rna
CN107873055B (zh) 2015-05-29 2021-09-17 库瑞瓦格房地产有限公司 包括至少一个切向流过滤步骤的产生和纯化rna的方法
EP3350314A4 (en) 2015-09-18 2019-02-06 Twist Bioscience Corporation BANKS OF OLIGONUCLEIC ACID VARIANTS AND SYNTHESIS THEREOF
CN108698012A (zh) 2015-09-22 2018-10-23 特韦斯特生物科学公司 用于核酸合成的柔性基底
EP3384077A4 (en) 2015-12-01 2019-05-08 Twist Bioscience Corporation FUNCTIONALIZED SURFACES AND THEIR PREPARATION
EP3500672A4 (en) 2016-08-22 2020-05-20 Twist Bioscience Corporation NOVO SYNTHESIZED NUCLEIC ACID BANKS
CN110248724B (zh) 2016-09-21 2022-11-18 特韦斯特生物科学公司 基于核酸的数据存储
EP3538549A1 (en) 2016-11-10 2019-09-18 iOmx Therapeutics AG Or10h1 antigen binding proteins and uses thereof
GB2573069A (en) 2016-12-16 2019-10-23 Twist Bioscience Corp Variant libraries of the immunological synapse and synthesis thereof
CA3054303A1 (en) 2017-02-22 2018-08-30 Twist Bioscience Corporation Nucleic acid based data storage
CN110913865A (zh) 2017-03-15 2020-03-24 特韦斯特生物科学公司 免疫突触的变体文库及其合成
KR20240059648A (ko) 2017-04-19 2024-05-07 더 보드 오브 리젠츠 오브 더 유니버시티 오브 텍사스 시스템 조작된 항원 수용체를 발현하는 면역 세포
CA3066744A1 (en) 2017-06-12 2018-12-20 Twist Bioscience Corporation Methods for seamless nucleic acid assembly
WO2018231864A1 (en) 2017-06-12 2018-12-20 Twist Bioscience Corporation Methods for seamless nucleic acid assembly
GB2581620A (en) 2017-09-11 2020-08-26 Twist Bioscience Corp GPCR binding proteins and synthesis thereof
CA3079613A1 (en) 2017-10-20 2019-04-25 Twist Bioscience Corporation Heated nanowells for polynucleotide synthesis
EP3735459A4 (en) 2018-01-04 2021-10-06 Twist Bioscience Corporation DNA-BASED DIGITAL INFORMATION STORAGE
EP3508499A1 (en) 2018-01-08 2019-07-10 iOmx Therapeutics AG Antibodies targeting, and other modulators of, an immunoglobulin gene associated with resistance against anti-tumour immune responses, and uses thereof
US20210163922A1 (en) 2018-03-19 2021-06-03 Modernatx, Inc. Assembly and error reduction of synthetic genes from oligonucleotides
WO2019222706A1 (en) 2018-05-18 2019-11-21 Twist Bioscience Corporation Polynucleotides, reagents, and methods for nucleic acid hybridization
US10842885B2 (en) 2018-08-20 2020-11-24 Ucl Business Ltd Factor IX encoding nucleotides
KR20210143766A (ko) 2019-02-26 2021-11-29 트위스트 바이오사이언스 코포레이션 Glp1 수용체에 대한 변이체 핵산 라이브러리
JP2022522668A (ja) 2019-02-26 2022-04-20 ツイスト バイオサイエンス コーポレーション 抗体を最適化するための変異体核酸ライブラリ
WO2020257612A1 (en) 2019-06-21 2020-12-24 Twist Bioscience Corporation Barcode-based nucleic acid sequence assembly
EP3989994A4 (en) * 2019-06-30 2023-08-09 John Fraser Wright RECOMBINANT AAV VECTORS WITH ALTERED IMMUNOGENICITY AND METHODS FOR THEIR PRODUCTION
KR20220051164A (ko) 2019-07-05 2022-04-26 아이오엠엑스 테라퓨틱스 아게 Igsf11 (vsig3)의 항체 결합 igc2 및 이의 용도
EP3822288A1 (en) 2019-11-18 2021-05-19 Deutsches Krebsforschungszentrum, Stiftung des öffentlichen Rechts Antibodies targeting, and other modulators of, the cd276 antigen, and uses thereof
US20240010720A1 (en) 2020-07-06 2024-01-11 Iomx Therapeutics Ag Antibodies binding igv of igsf11 (vsig3) and uses thereof
WO2022096536A1 (en) 2020-11-03 2022-05-12 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Target-cell restricted, costimulatory, bispecific and bivalent anti-cd28 antibodies
EP3992205A1 (en) 2020-11-03 2022-05-04 Rheinische Friedrich-Wilhelms-Universität Bonn Sars coronavirus-2 spike protein binding compounds
WO2022106205A1 (en) 2020-11-18 2022-05-27 Rheinische Friedrich-Wilhelms-Universität Bonn Corona virus spike protein binding compounds
WO2022184845A1 (en) 2021-03-03 2022-09-09 Chemotherapeutisches Forschungsinstitut Georg-Speyer-Haus Bispecific antibodies enhancing cell mediated immune responses
TW202328446A (zh) * 2021-08-11 2023-07-16 美商堅固生物科技公司 肌肉萎縮症之治療
WO2024067780A1 (zh) * 2022-09-30 2024-04-04 南京金斯瑞生物科技有限公司 一种降低外源核酸免疫原性的密码子优化

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050131267A1 (en) * 1995-06-07 2005-06-16 Talmadge Karen D. System and method for delivering a therapeutic agent for bone disease
EP1003531B1 (en) * 1997-05-20 2007-08-22 Ottawa Health Research Institute Processes for preparing nucleic acid constructs
CA2388055A1 (en) * 1999-09-25 2001-04-05 University Of Iowa Research Foundation Immunostimulatory nucleic acids
ATE319814T1 (de) 2000-03-15 2006-03-15 Prolume Ltd Luciferase, fluoreszenzproteine, für luciferase und fluoreszenzproteine kodierend nukleinsaüre und ihre verwendung in der diagnose, hoch- durchsatz screeningsverfahren
EP1156112B1 (en) 2000-05-18 2006-03-01 Geneart GmbH Synthetic gagpol genes and their uses
US6919204B2 (en) * 2000-09-29 2005-07-19 Sangamo Biosciences, Inc. Modulation of gene expression using localization domains
DE10053781B4 (de) 2000-10-30 2008-07-03 Geneart Ag Kernexportreportersystem
CA2443275C (en) 2001-04-05 2013-02-05 Ml Laboratories Plc Improved gene expression
AU2002317771A1 (en) 2001-06-05 2002-12-16 Cellectis Methods for modifying the cpg content of polynucleotides
US7605138B2 (en) * 2002-07-03 2009-10-20 Coley Pharmaceutical Group, Inc. Nucleic acid compositions for stimulating immune responses
US7576066B2 (en) * 2002-07-03 2009-08-18 Coley Pharmaceutical Group, Inc. Nucleic acid compositions for stimulating immune responses
US7569553B2 (en) * 2002-07-03 2009-08-04 Coley Pharmaceutical Group, Inc. Nucleic acid compositions for stimulating immune responses
US7316925B2 (en) * 2002-07-16 2008-01-08 Vgx Pharmaceuticals, Inc. Codon optimized synthetic plasmids
DE10260805A1 (de) * 2002-12-23 2004-07-22 Geneart Gmbh Verfahren und Vorrichtung zum Optimieren einer Nucleotidsequenz zur Expression eines Proteins
JP4819802B2 (ja) 2004-05-12 2011-11-24 ノースロップ グラマン システムズ コーポレーション 複数のナビゲーションコンポーネントの整合システム及び方法
ATE453716T1 (de) 2004-08-03 2010-01-15 Geneart Ag Verfahren zur modulation der genexpression durch änderung des cpg gehalts
DE102004037611B4 (de) * 2004-08-03 2013-10-02 Geneart Ag Induzierbare Genexpression
DE102007052344B3 (de) * 2007-11-02 2009-03-12 Geneart Ag Selektion kodierender Nukleinsäure-Konstrukte auf Abwesenheit von Frameshift-Mutationen
EP2970965A2 (en) * 2013-03-15 2016-01-20 Pronai Therapeutics, Inc. Dnai for the modulation of genes

Also Published As

Publication number Publication date
US8859275B2 (en) 2014-10-14
US20150104832A1 (en) 2015-04-16
US20090324546A1 (en) 2009-12-31
BRPI0513081A (pt) 2008-04-22
IL180786A0 (en) 2007-06-03
ATE453716T1 (de) 2010-01-15
CA2575490A1 (en) 2006-02-16
EP1776460B1 (de) 2009-12-30
US20210155940A1 (en) 2021-05-27
AU2005270430B2 (en) 2008-06-12
JP4550115B2 (ja) 2010-09-22
EP1776460B2 (de) 2013-12-25
WO2006015789A3 (de) 2006-06-01
KR101222628B1 (ko) 2013-01-16
AU2005270430A1 (en) 2006-02-16
KR20070041605A (ko) 2007-04-18
EP1776460B8 (de) 2014-02-26
EP1776460A2 (de) 2007-04-25
WO2006015789A2 (de) 2006-02-16
US10273486B2 (en) 2019-04-30
DE502005008794D1 (de) 2010-02-11
IL180786A (en) 2013-08-29
DK1776460T3 (da) 2010-04-12
JP2008507986A (ja) 2008-03-21
US20190270999A1 (en) 2019-09-05
HK1100089A1 (en) 2007-09-07

Similar Documents

Publication Publication Date Title
HK1100089A1 (en) Method for modulating gene expression by modifying the cpg content
WO2003014307A3 (en) Antisense modulation of apolipoprotein(a) expression
WO2004044181A3 (en) Antisense modulation of apolipoprotein b expression
WO2004005460A3 (en) Antisense modulation of hmg-coa reductase expression
WO2003011887A3 (en) Antisense modulation of apolipoprotein b expression
WO2002036743A3 (en) Antisense modulation of calreticulin expression
AU2001290706A1 (en) Antisense modulation of clusterin expression
WO2003097662A8 (en) Antisense modulation of apolipoprotein b expression
MX2007006610A (es) Metodo para simplificar acidos nucleicos microbianos por modificacion quimica de citosinas.
WO2003046132A3 (en) Antisense modulation of myd88 expression
WO2003014306A3 (en) Antisense modulation of cholesteryl ester transfer protein expression
WO2001083513A3 (en) Antisense modulation of inhibitor of dna binding-1 expression
WO2002095053A3 (en) Antisense modulation of src-c expression
WO2002050248A3 (en) Antisense modulation of hepsin expression
WO2004010956A3 (en) Antisense modulation of lar expression
WO2003052062A3 (en) Antisense modulation of cd36l1 expression
WO2003027229A3 (en) Antisense modulation of rip2 expression
EP1572713A4 (en) ANTISENSE MODULATION OF ACYL-COA SYNTHETASE 1 EXPRESSION
WO2004003201A3 (en) Antisense modulation of lrh1 expression
WO2003106645A3 (en) ANTISENSE MODULATION OF SMRT COREPRESSOR EXPRESSION
WO2002041836A3 (en) Antisense modulation of src-1 expression
WO2003050247A3 (en) Antisense modulation of mhc class ii transactivator expression
WO2004015126A3 (en) Antisense modulation of edg1 expression
WO2003099204A3 (en) Antisense modulation of inhibitor-kappa b kinase-beta expression
WO2002042425A3 (en) Antisense modulation of mp-1 expression

Legal Events

Date Code Title Description
FA Abandonment or withdrawal