MX166479B - Composicion farmaceutica que contiene carbinolimidazoles - Google Patents

Composicion farmaceutica que contiene carbinolimidazoles

Info

Publication number
MX166479B
MX166479B MX017145A MX1714589A MX166479B MX 166479 B MX166479 B MX 166479B MX 017145 A MX017145 A MX 017145A MX 1714589 A MX1714589 A MX 1714589A MX 166479 B MX166479 B MX 166479B
Authority
MX
Mexico
Prior art keywords
carbinolimidazoles
pharmaceutical composition
composition containing
carbinoloimidazoles
alkyl
Prior art date
Application number
MX017145A
Other languages
English (en)
Inventor
Douglas Guy Batt
Richard Scot Greenberg
Richard Russell Harris
Original Assignee
Du Pont Merck Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont Merck Pharma filed Critical Du Pont Merck Pharma
Publication of MX166479B publication Critical patent/MX166479B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

a presente invención se refiere a una composición farmacéutica que consiste esencialmente de un portador farmacéutico apropiado y una cantidad antiinflamatoria de un compuesto de la fórmula; o una sal farmacéuticamente aceptable del mismo en donde R1 y R 1 independientemente son H, F, C1, BR, CH3, CF3, O S (0)n R3 en donde n es 0, 1 ó 2 y R3 es alquilo de 1 a 4 átomos de carbono, R4 es H o alquilo de 1 a 4 átomos de carbono, con la condición de queR4 es H cuando m es 2 ó 3 y m es de 1 a 3.
MX017145A 1988-08-10 1989-08-10 Composicion farmaceutica que contiene carbinolimidazoles MX166479B (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/230,448 US4859693A (en) 1988-08-10 1988-08-10 Antiinflammatory carbinoloimidazoles

Publications (1)

Publication Number Publication Date
MX166479B true MX166479B (es) 1993-01-12

Family

ID=22865262

Family Applications (1)

Application Number Title Priority Date Filing Date
MX017145A MX166479B (es) 1988-08-10 1989-08-10 Composicion farmaceutica que contiene carbinolimidazoles

Country Status (18)

Country Link
US (1) US4859693A (es)
EP (1) EP0354539B1 (es)
JP (1) JPH0692301B2 (es)
KR (1) KR900002773A (es)
AT (1) ATE120643T1 (es)
AU (1) AU633261B2 (es)
CA (1) CA1336964C (es)
DE (1) DE68922038T2 (es)
DK (1) DK390589A (es)
ES (1) ES2070873T3 (es)
HU (1) HU207794B (es)
IL (1) IL91261A (es)
MX (1) MX166479B (es)
MY (1) MY104099A (es)
NO (1) NO893213L (es)
NZ (1) NZ230247A (es)
PT (1) PT91427B (es)
ZA (1) ZA896121B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5049570A (en) * 1990-01-23 1991-09-17 Du Pont Merck Pharmaceutical Company Pyridylphenyl nitrogen heterocycle-substituted carbinols and derivatives thereof with anti-inflammatory activity

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE44186B1 (en) * 1975-12-03 1981-09-09 Ici Ltd 1,2,4-triazolyl alkanols and their use as pesticides
JPS6048486B2 (ja) * 1976-01-01 1985-10-28 木場 常義 抗リウマチ剤
DE2623129C3 (de) * 1976-05-22 1980-04-10 Nordmark-Werke Gmbh, 2000 Hamburg U-Diphenyl-3-(imidazol-l-yl) -propan-2-ole, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE2732750A1 (de) * 1977-07-20 1979-02-08 Merck Patent Gmbh Basische thioaether und verfahren zu ihrer herstellung
US4413003A (en) * 1977-07-29 1983-11-01 Rohm And Haas Company β-Hydroxyarylethylimidazoles
DE2851143A1 (de) * 1978-11-25 1980-06-04 Bayer Ag Fluorenyl-azolylmethyl-carbinole, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2851116A1 (de) * 1978-11-25 1980-06-12 Bayer Ag Hydroxyethyl-azole, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2912288A1 (de) * 1979-03-28 1980-10-09 Bayer Ag Verfahren zur herstellung von hydroxyethyl-azolen
DE2920375A1 (de) * 1979-05-19 1980-11-20 Bayer Ag Fungizide mittel, verfahren zu ihrer herstellung sowie ihre verwendung als fungizide
US4414210A (en) * 1979-10-02 1983-11-08 Rohm And Haas Company 2-Hydroxyarylethyltriazole fungicides
GB2068228B (en) * 1980-01-24 1984-02-29 Janssen Pharmaceutica Nv Anti-microbial compositions for the topical treatment of acne vulgaris
DE3280075D1 (de) * 1981-11-27 1990-02-08 Ciba Geigy Ag Mikrobizide triazolyl-ethyl-aether.
US4569935A (en) * 1983-03-17 1986-02-11 University Of Tennessee Research Corp. Topical treatment of psoriasis with imidazole antibiotics
DE3579347D1 (de) * 1984-04-05 1990-10-04 Ici Plc Azolylpropanole.
US4766140A (en) * 1984-06-18 1988-08-23 Eli Lilly And Company Method of inhibiting aromatase
DE102007058724B3 (de) * 2007-12-06 2009-05-14 Fujitsu Siemens Computers Gmbh Datenverarbeitungssystem

Also Published As

Publication number Publication date
DE68922038T2 (de) 1995-08-03
ATE120643T1 (de) 1995-04-15
AU3943989A (en) 1990-02-15
DK390589A (da) 1990-02-11
ES2070873T3 (es) 1995-06-16
NO893213D0 (no) 1989-08-09
HU207794B (en) 1993-06-28
ZA896121B (en) 1991-04-24
NO893213L (no) 1990-02-12
US4859693A (en) 1989-08-22
EP0354539A3 (en) 1991-11-13
PT91427A (pt) 1990-03-08
PT91427B (pt) 1995-05-31
IL91261A (en) 1994-01-25
IL91261A0 (en) 1990-03-19
HUT51895A (en) 1990-06-28
EP0354539B1 (en) 1995-04-05
DE68922038D1 (de) 1995-05-11
EP0354539A2 (en) 1990-02-14
NZ230247A (en) 1991-12-23
JPH0692301B2 (ja) 1994-11-16
KR900002773A (ko) 1990-03-23
CA1336964C (en) 1995-09-12
AU633261B2 (en) 1993-01-28
DK390589D0 (da) 1989-08-09
JPH0291021A (ja) 1990-03-30
MY104099A (en) 1993-11-30

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