MD663F1 - Erythromycin derivatives, their process for obtaining them and their use as medicines Erythromycin derivatives, method for their preparation and use them as drugs - Google Patents

Erythromycin derivatives, their process for obtaining them and their use as medicines Erythromycin derivatives, method for their preparation and use them as drugs

Info

Publication number
MD663F1
MD663F1 MD95-0431A MD950431A MD663F1 MD 663 F1 MD663 F1 MD 663F1 MD 950431 A MD950431 A MD 950431A MD 663 F1 MD663 F1 MD 663F1
Authority
MD
Moldova
Prior art keywords
erythromycin derivatives
medicines
drugs
obtaining
preparation
Prior art date
Application number
MD95-0431A
Other languages
Romanian (ro)
Other versions
MD663G2 (en
Inventor
Constantin Agouridas
Yannick Benedetti
Jean-Fran Ois Chantot
Alexis Denis
Martret Odile Le
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of MD663F1 publication Critical patent/MD663F1/en
Publication of MD663G2 publication Critical patent/MD663G2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
MD95-0431A 1994-04-08 1995-04-06 Erythromycin derivatives,method for their preparation and use thereof as drugs MD663G2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9404154A FR2718450B1 (en) 1994-04-08 1994-04-08 New erythromycin derivatives, their preparation process and their use as drugs.
PCT/FR1995/000441 WO1995027720A1 (en) 1994-04-08 1995-04-06 Novel erythromycin derivatives, method for preparing same and use thereof as drugs

Publications (2)

Publication Number Publication Date
MD663F1 true MD663F1 (en) 1997-01-31
MD663G2 MD663G2 (en) 1997-07-31

Family

ID=9461886

Family Applications (1)

Application Number Title Priority Date Filing Date
MD95-0431A MD663G2 (en) 1994-04-08 1995-04-06 Erythromycin derivatives,method for their preparation and use thereof as drugs

Country Status (49)

Country Link
US (2) US5656607A (en)
EP (1) EP0676409B1 (en)
JP (1) JP3000023B2 (en)
KR (1) KR100317148B1 (en)
CN (1) CN1059445C (en)
AP (1) AP587A (en)
AT (1) ATE234853T1 (en)
AU (1) AU684939B2 (en)
BG (1) BG61916B1 (en)
BR (1) BR9506147A (en)
CA (1) CA2164638C (en)
CO (1) CO4370097A1 (en)
CZ (1) CZ296005B6 (en)
DE (1) DE69529934T2 (en)
DK (1) DK0676409T3 (en)
DZ (1) DZ1869A1 (en)
EE (1) EE04498B1 (en)
ES (1) ES2189820T3 (en)
FI (1) FI111264B (en)
FR (1) FR2718450B1 (en)
GB (1) GB2288174A (en)
GE (1) GEP19991836B (en)
HR (1) HRP950217B1 (en)
HU (1) HU215396B (en)
IL (1) IL112954A (en)
IS (1) IS1865B (en)
JO (1) JO1850B1 (en)
LV (1) LV11182B (en)
MA (1) MA23501A1 (en)
MD (1) MD663G2 (en)
MY (1) MY114672A (en)
NO (1) NO308361B1 (en)
NZ (1) NZ284498A (en)
OA (1) OA10200A (en)
PE (1) PE2896A1 (en)
PL (1) PL180837B1 (en)
PT (1) PT676409E (en)
RO (1) RO115634B1 (en)
RU (1) RU2141965C1 (en)
SA (1) SA97170757A (en)
SI (1) SI0676409T1 (en)
SK (1) SK284079B6 (en)
SV (1) SV1995000018A (en)
TN (1) TNSN95026A1 (en)
TW (1) TW316908B (en)
UA (1) UA44705C2 (en)
WO (1) WO1995027720A1 (en)
YU (1) YU49221B (en)
ZA (1) ZA952059B (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD1222Y (en) * 2017-05-31 2018-01-31 ИНСТИТУТ ЭЛЕКТРОННОЙ ИНЖЕНЕРИИ И НАНОТЕХНОЛОГИЙ "D. Ghitu" АНМ Process for treating planting material of flowers before planting

Families Citing this family (48)

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FR2732023B1 (en) * 1995-03-22 1997-04-30 Roussel Uclaf NOVEL ERYTHROMYCIN DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS
FR2742757B1 (en) * 1995-12-22 1998-01-30 Roussel Uclaf NOVEL ERYTHROMYCIN DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS
FR2745289B1 (en) * 1996-02-28 1998-05-29 Roussel Uclaf NOVEL DERIVATIVES OF CARBOXYLIC ACID 1 (2H) QUINOLEIN, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATION TO THE SYNTHESIS OF PRODUCTS WITH ANTIBIOTIC PROPERTIES
US5750510A (en) * 1997-04-04 1998-05-12 Abbott Laboratories 3-descladinose-2,3-anhydroerythromycin derivatives
DE69723848T2 (en) * 1996-05-07 2004-07-01 Abbott Laboratories, Abbott Park 3-descladinose-2,3-anhydroerythromycin DERIVATIVES
FR2748746B1 (en) * 1996-05-14 1998-08-14 Hoechst Marion Roussel Inc NEW PROCESS FOR ISOMERIZATION OF RADICAL METHYL IN 10 FROM ERYTHROMYCIN DERIVATIVES
FR2751656B1 (en) * 1996-07-24 1998-10-16 Hoechst Marion Roussel Inc NOVEL ERYTHROMYCIN DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS
UA51730C2 (en) * 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-0-substituted ketolides having antibacterial activity
EP1291352B1 (en) * 1996-09-04 2005-05-25 Abbott Laboratories 6-O-substituted ketolides having antibacterial activity
FR2757168B1 (en) * 1996-12-12 1999-06-11 Hoechst Marion Roussel Inc NOVEL ERYTHROMYCIN DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS
FR2760017B1 (en) * 1997-02-27 1999-04-30 Hoechst Marion Roussel Inc NOVEL ERYTROMYCIN DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS
AU4472897A (en) * 1997-03-10 1998-09-29 Taisho Pharmaceutical Co., Ltd. Erythromycin a derivatives
US6140479A (en) * 1997-03-24 2000-10-31 Taisho Pharmaceuticals Co., Ltd. Erythromycin a derivatives
US6162794A (en) * 1997-05-09 2000-12-19 Pfizer Inc. Erythromycin derivatives
US5922683A (en) * 1997-05-29 1999-07-13 Abbott Laboratories Multicyclic erythromycin derivatives
ID24529A (en) * 1997-06-11 2000-07-20 Pfizer Prod Inc 9-OKSIMA ERITROMICIN DESIGNS
FR2771008B1 (en) * 1997-11-17 2000-04-28 Hoechst Marion Roussel Inc USE OF KETOLIDES FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS FOR PREVENTING ARTERIAL THROMBOTIC COMPLICATIONS LINKED TO ATHEROSCLEROSIS
AP1060A (en) * 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
WO2000017218A1 (en) 1998-09-22 2000-03-30 Pfizer Products Inc. Carbamate and carbazate ketolide antibiotics
FR2786188B1 (en) * 1998-11-24 2002-10-31 Hoechst Marion Roussel Inc NOVEL ERYTHROMYCIN DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS
DE69933897T2 (en) 1998-12-10 2007-03-15 Pfizer Products Inc., Groton Carbamate and carbazate ketolide antibiotics
EP1749832A3 (en) * 1998-12-10 2008-03-26 Pfizer Products Incorporated Carbamate and carbazate ketolide antibiotics
EP1298138B1 (en) * 1998-12-10 2006-11-02 Pfizer Products Inc. Carbamate and Carbazate Ketolide Antibiotics
FR2789392B1 (en) * 1999-02-04 2001-10-05 Hoechst Marion Roussel Inc NOVEL ERYTHROMYCIN DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS
US6054435A (en) * 1999-03-19 2000-04-25 Abbott Laboratories 6-O-substituted macrolides having antibacterial activity
CN1241931C (en) * 1999-04-16 2006-02-15 高山生物科学股份有限公司 Macrolide antinfective agents
MXPA01010521A (en) 1999-04-16 2003-08-19 Johnson & Johnson Ketolide antibacterials.
US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
IL145739A0 (en) * 1999-05-24 2002-07-25 Pfizer Prod Inc 13-methyl-erythromycin derivatives
CA2451391A1 (en) * 2001-07-03 2003-01-16 Chiron Corporation C12 modified erythromycin macrolides and ketolides having antibacterial activity
JP2006508643A (en) 2002-07-01 2006-03-16 アーキオン ライフ サイエンシーズ エルエルシー ディー／ビー／エー バイオ−テクニカル リソーセズ ディビジョン Processes and materials for the production of glucosamine and N-acetylglucosamine
ES2552682T3 (en) * 2003-03-10 2015-12-01 Merck Sharp & Dohme Corp. Novel antibacterial agents
US7332476B2 (en) * 2003-04-25 2008-02-19 Novartis Ag Pyridyl substituted ketolide antibiotics
CA2523541A1 (en) * 2003-04-25 2004-11-11 Chiron Corporation Novel ketolide derivatives
EP2214484A4 (en) * 2007-10-25 2013-01-02 Cempra Pharmaceuticals Inc Process for the preparation of macrolide antibacterial agents
CN105616437A (en) * 2008-10-24 2016-06-01 森普拉制药公司 Biodefenses using triazole-containing macrolides
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
EP2475253B1 (en) 2009-09-10 2016-10-26 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and mac diseases
CA2793884C (en) 2010-03-22 2019-09-10 Cempra Pharmaceuticals, Inc. Crystalline forms of a macrolide, and uses therefor
DK2571506T3 (en) 2010-05-20 2017-08-28 Cempra Pharmaceuticals Inc PROCEDURES FOR THE MANUFACTURE OF MACROLIDES AND KETOLIDES AND INTERMEDIATES
JP6042334B2 (en) 2010-09-10 2016-12-14 センプラ ファーマシューティカルズ，インコーポレイテッド Hydrogen bond forming fluoroketolides for disease treatment
AU2013239696C1 (en) 2012-03-27 2018-11-29 Cempra Pharmaceuticals, Inc. Parenteral formulations for administering macrolide antibiotics
EP2968801B1 (en) 2013-03-14 2018-09-26 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
US9751908B2 (en) 2013-03-15 2017-09-05 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents
CA2908575C (en) 2013-04-04 2021-11-16 President And Fellows Of Harvard College Macrolides and methods of their preparation and use
EP3211997A4 (en) * 2014-10-08 2018-10-24 President and Fellows of Harvard College 14-membered ketolides and methods of their preparation and use
US10640528B2 (en) 2015-03-25 2020-05-05 President And Fellows Of Havard College Macrolides with modified desosamine sugars and uses thereof
JP7199722B2 (en) 2019-12-25 2023-01-06 旭精工株式会社 Coin transport sorting mechanism and coin identification transport device provided with the same

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US3868414A (en) * 1973-01-22 1975-02-25 Merck & Co Inc Tetrahydrofluorene carboxylic acids and related compounds
DE2842759A1 (en) * 1978-09-30 1980-04-10 Merck Patent Gmbh BASIC AETHER, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND METHOD FOR THE PRODUCTION THEREOF
IL99995A (en) * 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
FR2692579B1 (en) * 1992-06-19 1995-06-02 Roussel Uclaf New picromycin derivatives, their preparation process and their use as medicines.
FR2697524B1 (en) * 1992-11-05 1994-12-23 Roussel Uclaf New erythromycin derivatives, their preparation process and their use as drugs.
US5527780A (en) * 1992-11-05 1996-06-18 Roussel Uclaf Erythromycin derivatives
HRP930014A2 (en) * 1993-01-08 1994-08-31 Pliva Pharm & Chem Works 9-deoxo-9a-aza-11-deoxy-9a-homoeritromycin a 9a, 11-cyclic carbamates
FR2702480B1 (en) * 1993-03-09 1995-04-28 Roussel Uclaf New erythromycin derivatives, their preparation process and their use as drugs.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD1222Y (en) * 2017-05-31 2018-01-31 ИНСТИТУТ ЭЛЕКТРОННОЙ ИНЖЕНЕРИИ И НАНОТЕХНОЛОГИЙ "D. Ghitu" АНМ Process for treating planting material of flowers before planting

Also Published As

Publication number Publication date
HU9503505D0 (en) 1996-02-28
YU49221B (en) 2004-11-25
RU2141965C1 (en) 1999-11-27
DE69529934T2 (en) 2003-09-04
DZ1869A1 (en) 2002-02-17
AP9500743A0 (en) 1995-07-31
JO1850B1 (en) 1995-12-27
PL311871A1 (en) 1996-03-18
HRP950217B1 (en) 2004-06-30
MD663G2 (en) 1997-07-31
UA44705C2 (en) 2002-03-15
JPH07278177A (en) 1995-10-24
CA2164638C (en) 2003-12-30
MA23501A1 (en) 1995-12-31
CZ322395A3 (en) 1996-08-14
FI955913A (en) 1995-12-08
IS1865B (en) 2003-05-02
BG100150A (en) 1996-06-28
LV11182B (en) 1997-04-20
SK284079B6 (en) 2004-09-08
EP0676409B1 (en) 2003-03-19
LV11182A (en) 1996-04-20
MY114672A (en) 2002-12-31
WO1995027720A1 (en) 1995-10-19
BR9506147A (en) 1996-04-16
DE69529934D1 (en) 2003-04-24
ATE234853T1 (en) 2003-04-15
FR2718450B1 (en) 1997-01-10
HUT73772A (en) 1996-09-30
CN1126997A (en) 1996-07-17
ZA952059B (en) 1996-03-13
SK154695A3 (en) 1996-10-02
PT676409E (en) 2003-08-29
TNSN95026A1 (en) 1996-02-06
US5760233A (en) 1998-06-02
EE04498B1 (en) 2005-06-15
NO308361B1 (en) 2000-09-04
SI0676409T1 (en) 2003-06-30
CN1059445C (en) 2000-12-13
SV1995000018A (en) 1997-10-24
PL180837B1 (en) 2001-04-30
CA2164638A1 (en) 1995-10-19
FI111264B (en) 2003-06-30
EE9500080A (en) 1996-12-16
DK0676409T3 (en) 2003-06-23
CZ296005B6 (en) 2005-12-14
AU684939B2 (en) 1998-01-08
OA10200A (en) 1996-12-18
FI955913A0 (en) 1995-12-08
PE2896A1 (en) 1996-02-12
AP587A (en) 1997-04-29
AU2310795A (en) 1995-10-30
SA97170757A (en) 2005-12-03
RO115634B1 (en) 2000-04-28
US5656607A (en) 1997-08-12
CO4370097A1 (en) 1996-10-07
GEP19991836B (en) 1999-11-05
IL112954A (en) 2000-07-16
IS4309A (en) 1995-11-17
HRP950217A2 (en) 1997-08-31
KR100317148B1 (en) 2002-06-22
NZ284498A (en) 1997-07-27
FR2718450A1 (en) 1995-10-13
GB2288174A (en) 1995-10-11
NO954942L (en) 1996-02-07
TW316908B (en) 1997-10-01
HU215396B (en) 1998-12-28
ES2189820T3 (en) 2003-07-16
GB9506856D0 (en) 1995-05-24
EP0676409A1 (en) 1995-10-11
BG61916B1 (en) 1998-09-30
JP3000023B2 (en) 2000-01-17
YU21695A (en) 1997-12-05
IL112954A0 (en) 1995-06-29
NO954942D0 (en) 1995-12-06

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Legal Events

Date Code Title Description
FG3A Granted patent for invention
IF99 Valid patent on 19990615

Free format text: EXPIRES: 20150406

MM4A Patent for invention definitely lapsed due to non-payment of fees