MXPA01010521A - Ketolide antibacterials. - Google Patents

Ketolide antibacterials.

Info

Publication number
MXPA01010521A
MXPA01010521A MXPA01010521A MXPA01010521A MXPA01010521A MX PA01010521 A MXPA01010521 A MX PA01010521A MX PA01010521 A MXPA01010521 A MX PA01010521A MX PA01010521 A MXPA01010521 A MX PA01010521A MX PA01010521 A MXPA01010521 A MX PA01010521A
Authority
MX
Mexico
Prior art keywords
ketolide
antibacterials
ketolide antibacterials
Prior art date
Application number
MXPA01010521A
Other languages
Spanish (es)
Inventor
Daniel Chu
Original Assignee
Johnson & Johnson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Johnson & Johnson filed Critical Johnson & Johnson
Publication of MXPA01010521A publication Critical patent/MXPA01010521A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
MXPA01010521A 1999-04-16 2000-04-13 Ketolide antibacterials. MXPA01010521A (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US12972999P 1999-04-16 1999-04-16
US13138399P 1999-04-28 1999-04-28
US14017599P 1999-06-18 1999-06-18
US17215499P 1999-12-17 1999-12-17
US17215999P 1999-12-17 1999-12-17
PCT/US2000/010276 WO2000062783A2 (en) 1999-04-16 2000-04-13 Ketolide antibacterials

Publications (1)

Publication Number Publication Date
MXPA01010521A true MXPA01010521A (en) 2003-08-19

Family

ID=27537847

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA01010521A MXPA01010521A (en) 1999-04-16 2000-04-13 Ketolide antibacterials.

Country Status (10)

Country Link
US (2) US6458771B1 (en)
EP (1) EP1171447A2 (en)
JP (1) JP2002542197A (en)
CN (1) CN1373767A (en)
AU (1) AU4354900A (en)
CA (1) CA2370743A1 (en)
IL (1) IL145976A0 (en)
MX (1) MXPA01010521A (en)
NZ (1) NZ514917A (en)
WO (1) WO2000062783A2 (en)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AP1060A (en) * 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
FR2781484B1 (en) * 1998-07-21 2001-08-10 Hoechst Marion Roussel Inc NOVEL 6-DEOXY ERYTHROMYCIN DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS
ID30233A (en) 1999-01-27 2001-11-15 Pfizer Prod Inc ANTIBIOTICS OF TETOLIDA
DE60030847T2 (en) 1999-04-16 2007-04-19 Kosan Biosciences, Inc., Hayward ANTI-INFECTIOUS MAKROLIDE DERIVATIVES
US6590083B1 (en) * 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
US6451768B1 (en) 1999-04-16 2002-09-17 Kosan Biosciences, Inc. Macrolide antiinfective agents
BR0010938A (en) 1999-05-24 2002-03-19 Pfizer Prod Inc 13-Methyl erythromycin derivatives
CA2399198A1 (en) 2000-02-18 2001-08-23 Christopher Carreras Motilide compounds
CA2429709A1 (en) * 2000-12-01 2002-07-04 Gary Ashley Motilide compounds
US6472372B1 (en) 2000-12-06 2002-10-29 Ortho-Mcneil Pharmaceuticals, Inc. 6-O-Carbamoyl ketolide antibacterials
CN1589277A (en) 2001-09-17 2005-03-02 奥索-麦克尼尔药品公司 6-O-carbamate-11,12-lacto-ketolide antimicrobials
RU2004117082A (en) 2001-12-05 2005-04-10 Орто-Макнейл Фармасьютикал, Инк. (Us) KETOLIDE 6-0-ACYL DERIVATIVES OF ERYTHROMYCIN AS ANTIBACTERIAL MEANS
US8063021B2 (en) * 2002-01-17 2011-11-22 Kosan Biosciences Incorporated Ketolide anti-infective compounds
US20040033970A1 (en) * 2002-04-30 2004-02-19 Clark Richard F. Antibacterial compounds with improved pharmacokinetic profiles
US20050267054A1 (en) * 2002-04-30 2005-12-01 Clark Richard F Antibacterial compounds with improved pharmacokinetic profiles
US6841664B2 (en) 2002-07-25 2005-01-11 Enanra Pharmaceuticals, Inc. 6,11-4-carbon bridged ketolides
US7064110B2 (en) * 2002-05-13 2006-06-20 Enanta Pharmaceuticals, Inc. 6-11 bicycle ketolide derivatives
US6753318B1 (en) 2002-07-25 2004-06-22 Enanta Pharmaceuticals, Inc. 6,11-4-carbon bridged erythromycin derivatives
US7135573B2 (en) * 2002-05-13 2006-11-14 Enanta Pharmaceuticals, Inc. Processes for the preparation of O-(6-Pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine
US7273853B2 (en) * 2002-05-13 2007-09-25 Enanta Pharmaceuticals, Inc. 6-11 bicyclic ketolide derivatives
US7910558B2 (en) * 2002-05-13 2011-03-22 Enanta Pharmaceuticals, Inc. Bridged macrocyclic compounds and processes for the preparation thereof
NZ536402A (en) * 2002-05-13 2006-08-31 Enanta Pharm Inc 6,11 bicyclic erythromycin derivatives
US6764998B1 (en) 2003-06-18 2004-07-20 Enanta Pharmaceuticals, Inc. 6,11-4C-bicyclic 9a-azalide derivatives
US6878691B2 (en) * 2002-05-13 2005-04-12 Enanta Pharmaceuticals, Inc. 6-11 bicyclic ketolide derivatives
WO2005070918A1 (en) * 2002-05-13 2005-08-04 Enanta Pharmaceuticals, Inc. Process for the preparation of t-11 bicyclic erythromycin derivatives
AU2003234650A1 (en) 2002-05-31 2003-12-19 Janssen Pharmaceutica N.V. 3-descladinosyl-6-o-carbamoyl and 6-o-carbonoyl macrolide antibacterial agents
US6727229B2 (en) * 2002-08-19 2004-04-27 Enanta Pharmaceuticals, Inc. 11,12-substituted lactone ketolide derivatives having antibacterial activity
EP3738591A3 (en) 2003-03-10 2021-03-24 Merck Sharp & Dohme Corp. Novel antibacterial agents
US6645941B1 (en) 2003-03-26 2003-11-11 Enanta Pharmaceuticals, Inc. 6,11-3C-bicyclic 9a-azalide derivatives
US20040254126A1 (en) * 2003-06-05 2004-12-16 Yao-Ling Qiu 11-12 Bicyclic erythromycin derivatives
US6790835B1 (en) 2003-06-05 2004-09-14 Enanta Pharmaceuticals, Inc. Bicyclic macrolide derivatives
US6716820B1 (en) 2003-06-05 2004-04-06 Enanta Pharmaceuticals, Inc. 6-O-substituted bicyclic macrolides
US6765016B1 (en) 2003-06-05 2004-07-20 Enanta Pharmaceuticals, Inc. Bicyclic ketolide derivatives
US6774115B1 (en) 2003-06-05 2004-08-10 Enanta Pharmaceuticals, Inc. 6-O-substituted bicyclic ketolides
US20050113319A1 (en) * 2003-08-26 2005-05-26 Christopher Carreras 11-Deoxy-6,9-ether erythromycin compounds
US7407941B2 (en) * 2003-08-26 2008-08-05 Pfizer, Inc. N-desmethyl-N-substituted-11-deoxyerythromycin compounds
WO2005030227A1 (en) * 2003-09-23 2005-04-07 Enanta Pharmaceuticals, Inc. 9a, 11-3C-BICYCLIC 9a-AZALIDE DERIVATIVES
WO2005067564A2 (en) * 2004-01-07 2005-07-28 Enanta Pharmaceuticals, Inc. 6-11 bicyclic erythromycin derivatives
US7265094B2 (en) * 2004-01-09 2007-09-04 Enanta Pharmaceuticals, Inc. 9N-substituted 6-11 bicyclic erythromycin derivatives
BRPI0513903A (en) * 2004-07-28 2008-05-20 Ranbaxy Lab Ltd ketolide derivatives useful as antimicrobial agents, their preparation processes and pharmaceutical compositions comprising the same
EP1771456A2 (en) * 2004-07-30 2007-04-11 Palumed SA Hybrid qa molecules wherein q is an aminoquinoline and a is an antibiotic residue, their synthesis and their uses as antibacterial agent
FR2874922A1 (en) * 2004-07-30 2006-03-10 Palumed Sa New aminoquinoline-antibiotic hybrids, useful as antibacterials in human and veterinary medicine, disinfectants and in agriculture
WO2006046112A2 (en) * 2004-10-25 2006-05-04 Ranbaxy Laboratories Limited Ketolide derivatives as antibacterial agents
AP2007004026A0 (en) * 2004-12-21 2007-06-30 Pfizer Prod Inc Macrolides
CA2589019A1 (en) * 2005-01-12 2006-07-20 Alpharma Aps Erythromycin derivatives as antibacterial agents
US7384922B2 (en) * 2005-05-04 2008-06-10 Enanta Pharmaceuticals, Inc. 6-11 bridged oxime erythromycin derivatives
EP1960413A2 (en) * 2005-11-23 2008-08-27 Ranbaxy Laboratories Limited Macrolides derivatives as antibacterial agents
US20090005325A1 (en) * 2005-11-23 2009-01-01 Biswajit Bas Ketolide Derivatives as Antibacterial Agents
US7595300B2 (en) 2005-12-13 2009-09-29 Kosan Biosciences Incorporated 7-quinolyl ketolide antibacterial agents
CN100577678C (en) * 2006-06-19 2010-01-06 中国医学科学院药物研究所 Macrolide analogue drug double sidechain illotycin A derivative, synthesis method and uses
US8354383B2 (en) * 2007-09-17 2013-01-15 Enanta Pharmaceuticals, Inc. 6,11-bridged biaryl macrolides
US8273720B2 (en) * 2007-09-17 2012-09-25 Enanta Pharmaceuticals, Inc. 6,11-bicyclolides: bridged biaryl macrolide derivatives
AU2008335668C1 (en) * 2007-09-17 2013-05-30 Enanta Pharmaceuticals, Inc. 6, 11-bridged biaryl macrolides
JP5698979B2 (en) 2007-10-25 2015-04-08 センプラ ファーマシューティカルズ，インコーポレイテッド Process for preparing macrolide antibacterial agents
EP3031460A1 (en) 2008-10-24 2016-06-15 Cempra Pharmaceuticals Inc. Biodefenses using triazole-containing macrolides
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
AU2010292010B2 (en) 2009-09-10 2016-01-07 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and MAC diseases
US8975386B2 (en) 2010-03-22 2015-03-10 Cempra Pharmaceuticals, Inc. Crystalline forms of a macrolide, and uses therefor
US9051346B2 (en) 2010-05-20 2015-06-09 Cempra Pharmaceuticals, Inc. Process for preparing triazole-containing ketolide antibiotics
KR20180110181A (en) 2010-09-10 2018-10-08 셈프라 파마슈티컬스, 인크. Hydrogen bond forming fluoro ketolides for treating diseases
WO2013148891A1 (en) 2012-03-27 2013-10-03 Cempra Pharmaceuticals, Inc. Parenteral formulations for administering macrolide antibiotics
WO2014152326A1 (en) 2013-03-14 2014-09-25 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
AU2014233240B2 (en) 2013-03-15 2018-08-09 Cempra Pharmaceuticals, Inc. Convergent processes for preparing macrolide antibacterial agents
MX2015014026A (en) 2013-04-04 2016-08-03 Harvard College Macrolides and methods of their preparation and use.
WO2016057798A1 (en) * 2014-10-08 2016-04-14 President And Fellows Of Harvard College 14-membered ketolides and methods of their preparation and use
CN107530365A (en) 2015-03-25 2018-01-02 哈佛大学的校长及成员们 Macrolide of desosamine sugar with modification and application thereof
CN106554381A (en) * 2015-09-25 2017-04-05 苏州鹏旭医药科技有限公司 Ketolide antibiotics intermediate and its preparation method and application
US20240076293A1 (en) * 2020-12-28 2024-03-07 Georgia Tech Research Corporation Compositions and Methods for Inhibiting Fibrosis, Inflammation and Cancer

Family Cites Families (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4935340A (en) 1985-06-07 1990-06-19 Eli Lilly And Company Method of isolating antibiotic biosynthetic genes
GB8521402D0 (en) 1985-08-28 1985-10-02 Beecham Group Plc Chemical compounds
US4874748A (en) 1986-03-24 1989-10-17 Abbott Laboratories Cloning vectors for streptomyces and use thereof in macrolide antibiotic production
US4742049A (en) 1986-06-04 1988-05-03 Abbott Laboratories Semisynthetic erythromycin antibiotics
US5110728A (en) 1986-07-31 1992-05-05 Calgene, Inc. Acyl carrier protein - DNA sequence and synthesis
JP2787458B2 (en) 1989-01-20 1998-08-20 旭化成工業株式会社 Antibiotic L53-18A and production method thereof
US5087563A (en) 1990-03-09 1992-02-11 The United States Of America, As Represented By The Secretary Of Agriculture Acyl carrier protein-I/protein-A gene fusion, products and methods
US5141926A (en) 1990-04-18 1992-08-25 Abbott Laboratories Erythromycin derivatives
IL99995A (en) 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
US5824513A (en) 1991-01-17 1998-10-20 Abbott Laboratories Recombinant DNA method for producing erythromycin analogs
US6060234A (en) 1991-01-17 2000-05-09 Abbott Laboratories Polyketide derivatives and recombinant methods for making same
US6066721A (en) 1995-07-06 2000-05-23 Stanford University Method to produce novel polyketides
US5712146A (en) 1993-09-20 1998-01-27 The Leland Stanford Junior University Recombinant combinatorial genetic library for the production of novel polyketides
US5672491A (en) 1993-09-20 1997-09-30 The Leland Stanford Junior University Recombinant production of novel polyketides
FR2718450B1 (en) 1994-04-08 1997-01-10 Roussel Uclaf New erythromycin derivatives, their preparation process and their use as drugs.
FR2719587B1 (en) * 1994-05-03 1996-07-12 Roussel Uclaf New erythromycin derivatives, their preparation process and their use as drugs.
FR2732023B1 (en) 1995-03-22 1997-04-30 Roussel Uclaf NOVEL ERYTHROMYCIN DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS
AU706445B2 (en) 1995-07-06 1999-06-17 Brown University Research Foundation Cell-free synthesis of polyketides
FR2739620B1 (en) 1995-10-09 1997-12-19 Roussel Uclaf NOVEL DERIVATIVES OF 5-0-DESOSAMINYL 6-O-METHYL ERYTHRONOLIDE A, THEIR PREPARATION PROCESS AND THEIR APPLICATION TO THE PREPARATION OF BIOLOGICALLY ACTIVE PRODUCTS
FR2742757B1 (en) 1995-12-22 1998-01-30 Roussel Uclaf NOVEL ERYTHROMYCIN DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS
US6271255B1 (en) 1996-07-05 2001-08-07 Biotica Technology Limited Erythromycins and process for their preparation
PL331285A1 (en) 1996-07-05 1999-07-05 Biotica Tech Ltd Erythromycins and method of preparing them
UA51730C2 (en) 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-0-substituted ketolides having antibacterial activity
FR2754821B1 (en) * 1996-10-23 2003-04-04 Hoechst Marion Roussel Inc NOVEL ERYTHROMYCIN DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS
CA2288030A1 (en) 1997-04-30 1998-11-05 Kosan Biosciences, Inc. Combinatorial polyketide libraries produced using a modular pks gene cluster as scaffold
ATE244245T1 (en) 1997-09-02 2003-07-15 Mitsubishi Pharma Corp CONDENSED THIOPHENE DERIVATIVES AND THEIR MEDICAL APPLICATIONS
US6124269A (en) 1997-10-29 2000-09-26 Abbott Laboratories 2-Halo-6-O-substituted ketolide derivatives
AP1060A (en) * 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.
AP9801420A0 (en) 1998-01-02 1998-12-31 Pfizer Prod Inc Novel macrolides.
FR2777282B1 (en) 1998-04-08 2001-04-20 Hoechst Marion Roussel Inc NEW DERIVATIVES OF 2-FLUORO 3-DE ((2,6-DIDEOXY 3-C-METHYL 3-0-METHYL-ALPHA-L-RIBOHEXOPYRANOSYL) OXYL) 6-O-METHYL 3-OXO ERYTHROMYCIN, THEIR PREPARATION PROCESS AND THEIR APPLICATION TO THE SYNTHESIS OF ACTIVE INGREDIENTS OF MEDICINES
GB9814006D0 (en) 1998-06-29 1998-08-26 Biotica Tech Ltd Polyketides and their synthesis
OA11670A (en) 1998-11-03 2005-01-12 Pfizer Prod Inc Novel macrolide antibiotics.
DE69933897T2 (en) 1998-12-10 2007-03-15 Pfizer Products Inc., Groton Carbamate and carbazate ketolide antibiotics
ID30233A (en) 1999-01-27 2001-11-15 Pfizer Prod Inc ANTIBIOTICS OF TETOLIDA
BR0010938A (en) 1999-05-24 2002-03-19 Pfizer Prod Inc 13-Methyl erythromycin derivatives
CA2378671C (en) 1999-06-07 2007-04-24 Abbott Laboratories 6-o-carbamate ketolide derivatives

Also Published As

Publication number Publication date
CN1373767A (en) 2002-10-09
NZ514917A (en) 2004-02-27
CA2370743A1 (en) 2000-10-26
IL145976A0 (en) 2002-07-25
EP1171447A2 (en) 2002-01-16
WO2000062783A3 (en) 2001-02-15
JP2002542197A (en) 2002-12-10
US6399582B1 (en) 2002-06-04
AU4354900A (en) 2000-11-02
WO2000062783A2 (en) 2000-10-26
US6458771B1 (en) 2002-10-01

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