MD4740C1 - Применение (Z)-4,4-диметил-1-(4-нитрофенил)-2-(1H-1,2,4-триазол-1-ил)пент-1-ен-3-она в качестве активного соединения против фитопатогенных бактерий - Google Patents
Применение (Z)-4,4-диметил-1-(4-нитрофенил)-2-(1H-1,2,4-триазол-1-ил)пент-1-ен-3-она в качестве активного соединения против фитопатогенных бактерий Download PDFInfo
- Publication number
- MD4740C1 MD4740C1 MDA20200056A MD20200056A MD4740C1 MD 4740 C1 MD4740 C1 MD 4740C1 MD A20200056 A MDA20200056 A MD A20200056A MD 20200056 A MD20200056 A MD 20200056A MD 4740 C1 MD4740 C1 MD 4740C1
- Authority
- MD
- Moldova
- Prior art keywords
- dimethyl
- pent
- nitrophenyl
- triazole
- active compound
- Prior art date
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- HSYXNSUUVTWJTP-JYRVWZFOSA-N (z)-4,4-dimethyl-1-(4-nitrophenyl)-2-(1,2,4-triazol-1-yl)pent-1-en-3-one Chemical compound C1=NC=NN1/C(C(=O)C(C)(C)C)=C\C1=CC=C([N+]([O-])=O)C=C1 HSYXNSUUVTWJTP-JYRVWZFOSA-N 0.000 title claims abstract description 8
- 241000894006 Bacteria Species 0.000 title claims description 12
- 150000001875 compounds Chemical class 0.000 title claims description 10
- 230000003032 phytopathogenic effect Effects 0.000 title claims description 8
- 241000588698 Erwinia Species 0.000 claims description 4
- 241000589634 Xanthomonas Species 0.000 claims description 4
- 230000000844 anti-bacterial effect Effects 0.000 abstract description 16
- 150000002391 heterocyclic compounds Chemical class 0.000 abstract description 4
- NSPMIYGKQJPBQR-UHFFFAOYSA-N 4H-1,2,4-triazole Chemical class C=1N=CNN=1 NSPMIYGKQJPBQR-UHFFFAOYSA-N 0.000 abstract 1
- 239000003899 bactericide agent Substances 0.000 abstract 1
- 238000012360 testing method Methods 0.000 description 17
- 238000002360 preparation method Methods 0.000 description 9
- JWUCHKBSVLQQCO-UHFFFAOYSA-N 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol Chemical compound C=1C=C(F)C=CC=1C(C=1C(=CC=CC=1)F)(O)CN1C=NC=N1 JWUCHKBSVLQQCO-UHFFFAOYSA-N 0.000 description 7
- 239000005787 Flutriafol Substances 0.000 description 7
- 125000001376 1,2,4-triazolyl group Chemical class N1N=C(N=C1)* 0.000 description 6
- 230000001580 bacterial effect Effects 0.000 description 6
- STJLVHWMYQXCPB-UHFFFAOYSA-N propiconazole Chemical compound O1C(CCC)COC1(C=1C(=CC(Cl)=CC=1)Cl)CN1N=CN=C1 STJLVHWMYQXCPB-UHFFFAOYSA-N 0.000 description 6
- 241000588701 Pectobacterium carotovorum Species 0.000 description 5
- 150000003852 triazoles Chemical class 0.000 description 5
- 239000005822 Propiconazole Substances 0.000 description 4
- 240000003768 Solanum lycopersicum Species 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 3
- 241000588694 Erwinia amylovora Species 0.000 description 3
- 235000007688 Lycopersicon esculentum Nutrition 0.000 description 3
- 244000061456 Solanum tuberosum Species 0.000 description 3
- 235000002595 Solanum tuberosum Nutrition 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 235000013399 edible fruits Nutrition 0.000 description 3
- 230000000855 fungicidal effect Effects 0.000 description 3
- 230000005764 inhibitory process Effects 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 241000894007 species Species 0.000 description 3
- 239000000725 suspension Substances 0.000 description 3
- 238000003786 synthesis reaction Methods 0.000 description 3
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 description 2
- 241000815873 Xanthomonas euvesicatoria Species 0.000 description 2
- 230000000845 anti-microbial effect Effects 0.000 description 2
- 239000012153 distilled water Substances 0.000 description 2
- 239000000417 fungicide Substances 0.000 description 2
- 230000012010 growth Effects 0.000 description 2
- 238000000338 in vitro Methods 0.000 description 2
- 230000003993 interaction Effects 0.000 description 2
- 150000002576 ketones Chemical class 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 238000010899 nucleation Methods 0.000 description 2
- 239000000575 pesticide Substances 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- FHOIVKVRWCOMTB-UHFFFAOYSA-N 1-(2h-triazol-4-yl)prop-2-en-1-one Chemical class C=CC(=O)C=1C=NNN=1 FHOIVKVRWCOMTB-UHFFFAOYSA-N 0.000 description 1
- FMWWRALTYIWZEB-UHFFFAOYSA-N 3,3-dimethyl-1-(1,2,4-triazol-1-yl)butan-2-one Chemical compound CC(C)(C)C(=O)CN1C=NC=N1 FMWWRALTYIWZEB-UHFFFAOYSA-N 0.000 description 1
- BXRFQSNOROATLV-UHFFFAOYSA-N 4-nitrobenzaldehyde Chemical compound [O-][N+](=O)C1=CC=C(C=O)C=C1 BXRFQSNOROATLV-UHFFFAOYSA-N 0.000 description 1
- 229920001817 Agar Polymers 0.000 description 1
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 235000002566 Capsicum Nutrition 0.000 description 1
- 235000002567 Capsicum annuum Nutrition 0.000 description 1
- 240000004160 Capsicum annuum Species 0.000 description 1
- 240000008067 Cucumis sativus Species 0.000 description 1
- 235000009849 Cucumis sativus Nutrition 0.000 description 1
- 241000588921 Enterobacteriaceae Species 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 239000006002 Pepper Substances 0.000 description 1
- 239000001888 Peptone Substances 0.000 description 1
- 108010080698 Peptones Proteins 0.000 description 1
- 235000016761 Piper aduncum Nutrition 0.000 description 1
- 235000017804 Piper guineense Nutrition 0.000 description 1
- 244000203593 Piper nigrum Species 0.000 description 1
- 235000008184 Piper nigrum Nutrition 0.000 description 1
- 235000014443 Pyrus communis Nutrition 0.000 description 1
- 235000004789 Rosa xanthina Nutrition 0.000 description 1
- 241000220222 Rosaceae Species 0.000 description 1
- 235000002560 Solanum lycopersicum Nutrition 0.000 description 1
- 241000589636 Xanthomonas campestris Species 0.000 description 1
- 241000589652 Xanthomonas oryzae Species 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 230000000843 anti-fungal effect Effects 0.000 description 1
- 230000002365 anti-tubercular Effects 0.000 description 1
- 125000004429 atom Chemical group 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 230000000721 bacterilogical effect Effects 0.000 description 1
- 239000001511 capsicum annuum Substances 0.000 description 1
- 230000003197 catalytic effect Effects 0.000 description 1
- 125000004122 cyclic group Chemical group 0.000 description 1
- 230000035613 defoliation Effects 0.000 description 1
- 239000012895 dilution Substances 0.000 description 1
- 238000010790 dilution Methods 0.000 description 1
- 231100000676 disease causative agent Toxicity 0.000 description 1
- 235000021186 dishes Nutrition 0.000 description 1
- 238000003306 harvesting Methods 0.000 description 1
- 230000002363 herbicidal effect Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 239000000543 intermediate Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 208000013435 necrotic lesion Diseases 0.000 description 1
- 125000004433 nitrogen atom Chemical group N* 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 235000019319 peptone Nutrition 0.000 description 1
- 230000008635 plant growth Effects 0.000 description 1
- 235000012015 potatoes Nutrition 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 239000002689 soil Substances 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 230000000707 stereoselective effect Effects 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 125000000565 sulfonamide group Chemical group 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 229940042055 systemic antimycotics triazole derivative Drugs 0.000 description 1
- -1 vinyltriazole ketone Chemical class 0.000 description 1
- 230000001018 virulence Effects 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Изобретение относится к применению гетероциклических соединений, производных 1,2,4-триазола, в качестве антибактериального средства и может быть использовано в сельском хозяйстве.Сущность заявленного изобретения заключается в применении в качестве активного соединения против фитопатогенных бактерий рода Erwinia и Xanthomonas соединения (Z)-4,4-диметил-1-(4-нитрофенил)-2-(1H-1,2,4-триазол-1-ил)пент-1-ен-3-она с формулой: .Значения минимальной бактерицидной концентрации составляют 0,4...2,0 мкг/мл.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDA20200056A MD4740C1 (ru) | 2020-06-13 | 2020-06-13 | Применение (Z)-4,4-диметил-1-(4-нитрофенил)-2-(1H-1,2,4-триазол-1-ил)пент-1-ен-3-она в качестве активного соединения против фитопатогенных бактерий |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDA20200056A MD4740C1 (ru) | 2020-06-13 | 2020-06-13 | Применение (Z)-4,4-диметил-1-(4-нитрофенил)-2-(1H-1,2,4-триазол-1-ил)пент-1-ен-3-она в качестве активного соединения против фитопатогенных бактерий |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD4740B1 MD4740B1 (ru) | 2021-02-28 |
| MD4740C1 true MD4740C1 (ru) | 2021-09-30 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDA20200056A MD4740C1 (ru) | 2020-06-13 | 2020-06-13 | Применение (Z)-4,4-диметил-1-(4-нитрофенил)-2-(1H-1,2,4-триазол-1-ил)пент-1-ен-3-она в качестве активного соединения против фитопатогенных бактерий |
Country Status (1)
| Country | Link |
|---|---|
| MD (1) | MD4740C1 (ru) |
-
2020
- 2020-06-13 MD MDA20200056A patent/MD4740C1/ru active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| MD4740B1 (ru) | 2021-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG4A | Patent for invention issued | ||
| TC4A | Change of name of proprietor (patent for invention) |
Owner name: INSTITUTIA PUBLICA UNIVERSITATEA DE STAT DIN MOLDOVA, MD STR. A. MATEEVICI NR. 60, MD-2009, CHISINAU, REPUBLICA MOLDOVA Free format text: PREVIOUS NAME OF PROPRIETOR: INSTITUTUL DE CHIMIE AL MEC, MD |