MD4739C1 - Procedeu de sinteză a 3,3-dialilindolin-2-onei - Google Patents

Procedeu de sinteză a 3,3-dialilindolin-2-onei

Info

Publication number
MD4739C1
MD4739C1 MDA20190067A MD20190067A MD4739C1 MD 4739 C1 MD4739 C1 MD 4739C1 MD A20190067 A MDA20190067 A MD A20190067A MD 20190067 A MD20190067 A MD 20190067A MD 4739 C1 MD4739 C1 MD 4739C1
Authority
MD
Moldova
Prior art keywords
diallylindolin
synthesis
dialkylation
compound
reaction
Prior art date
Application number
MDA20190067A
Other languages
English (en)
Russian (ru)
Other versions
MD4739B1 (ro
Inventor
Флюр МАКАЕВ
Еужения СТЫНГАЧ
Сергей ПОГРЕБНОЙ
Вячеслав БОЛДЕСКУ
Original Assignee
Институт Химии Моки
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Институт Химии Моки filed Critical Институт Химии Моки
Priority to MDA20190067A priority Critical patent/MD4739C1/ro
Publication of MD4739B1 publication Critical patent/MD4739B1/ro
Publication of MD4739C1 publication Critical patent/MD4739C1/ro

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Abstract

Invenţia se referă la chimia farmaceutică, şi anume, la un procedeu de sinteză a compusului heterociclic 3,3-dialilindolin-2-ona, care posedă proprietăţi psihotrope: anticonvulsive şi tranchilizante.Esenţa invenţiei revendicate constă în sinteza 3,3-dialilindolin-2-onei (1) prin dialchilarea oxindolului (2) cu bromură de alil conform schemei de reacţie: .Reacţia de dialchilare decurge la temperatura de 60…65°C timp de 3...4 ore. După tratarea cu apă a amestecului de reacţie, produsul obţinut se supune extracţiei cu un solvent potrivit, din care compusul (1) se izolează şi se purifică prin procedee cunoscute.
MDA20190067A 2019-07-31 2019-07-31 Procedeu de sinteză a 3,3-dialilindolin-2-onei MD4739C1 (ro)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MDA20190067A MD4739C1 (ro) 2019-07-31 2019-07-31 Procedeu de sinteză a 3,3-dialilindolin-2-onei

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MDA20190067A MD4739C1 (ro) 2019-07-31 2019-07-31 Procedeu de sinteză a 3,3-dialilindolin-2-onei

Publications (2)

Publication Number Publication Date
MD4739B1 MD4739B1 (ro) 2021-01-31
MD4739C1 true MD4739C1 (ro) 2021-08-31

Family

ID=74479085

Family Applications (1)

Application Number Title Priority Date Filing Date
MDA20190067A MD4739C1 (ro) 2019-07-31 2019-07-31 Procedeu de sinteză a 3,3-dialilindolin-2-onei

Country Status (1)

Country Link
MD (1) MD4739C1 (ro)

Also Published As

Publication number Publication date
MD4739B1 (ro) 2021-01-31

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Legal Events

Date Code Title Description
FG4A Patent for invention issued
TC4A Change of name of proprietor (patent for invention)

Owner name: INSTITUTIA PUBLICA UNIVERSITATEA DE STAT DIN MOLDOVA, MD STR. A. MATEEVICI NR. 60, MD-2009, CHISINAU, REPUBLICA MOLDOVA

Free format text: PREVIOUS NAME OF PROPRIETOR: INSTITUTUL DE CHIMIE AL MEC, MD STR. ACADEMIEI NR. 3, MD-2028, REPUBLICA MOLDOVA