MD4469B1 - Utilizarea di(µ-S)-bis{(4-aminobenzensulfamid)-cloro-[2-picoliden-4-feniltiosemicarbazidato-(1-)]cupru(II)} în calitate de antioxidant - Google Patents

Utilizarea di(µ-S)-bis{(4-aminobenzensulfamid)-cloro-[2-picoliden-4-feniltiosemicarbazidato-(1-)]cupru(II)} în calitate de antioxidant

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Publication number
MD4469B1
MD4469B1 MDA20160122A MD20160122A MD4469B1 MD 4469 B1 MD4469 B1 MD 4469B1 MD A20160122 A MDA20160122 A MD A20160122A MD 20160122 A MD20160122 A MD 20160122A MD 4469 B1 MD4469 B1 MD 4469B1
Authority
MD
Moldova
Prior art keywords
antioxidant
picolidene
phenylthiosemicarbazidato
aminobenzenesulphamide
chloro
Prior art date
Application number
MDA20160122A
Other languages
English (en)
Russian (ru)
Other versions
MD4469C1 (ro
Inventor
Аурелиан ГУЛЯ
Валентин ГУДУМАК
Ольга ГАРБУЗ
Виктор ЦАПКОВ
Елена-Михаела ПАХОНЦУ
Original Assignee
Государственный Университет Молд0
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Государственный Университет Молд0 filed Critical Государственный Университет Молд0
Priority to MDA20160122A priority Critical patent/MD4469C1/ro
Publication of MD4469B1 publication Critical patent/MD4469B1/ro
Publication of MD4469C1 publication Critical patent/MD4469C1/ro

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Invenţia se referă la chimie şi medicină, şi anume la utilizarea unui compus coordinativ din clasa tiosemicarbazonaţilor biometalelor în calitate de antioxidant şi poate găsi aplicare în medicină în calitate de substanţă, care inhibă sau încetineşte esenţial procesele de oxidare ale moleculelor organice în organismul uman.Esenţa invenţiei constă în utilizarea în calitate de antoxidant a di(µ-S)-bis{(4-aminobenzensulfamid)-cloro-[2-picoliden-4-feniltiosemicarbazidato-(1-)]-cupru(II)} cu formula:Rezultatul tehnic al invenţiei constă în stabilirea la compusul dat a activităţii antioxidative, care depăşeşte de 33,3 ori activitatea Troloxului şi de 1,6 ori caracteristicile analoage ale celui mai activ antioxidant sintetic care conţine un fragment tioamidic - derivatul cumariltiazolului.
MDA20160122A 2016-11-03 2016-11-03 Utilizarea di(µ-S)-bis{(4-aminobenzensulfamid)-cloro-[2-picoliden-4-feniltiosemicarbazidato-(1-)]cupru(II)} în calitate de antioxidant MD4469C1 (ro)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MDA20160122A MD4469C1 (ro) 2016-11-03 2016-11-03 Utilizarea di(µ-S)-bis{(4-aminobenzensulfamid)-cloro-[2-picoliden-4-feniltiosemicarbazidato-(1-)]cupru(II)} în calitate de antioxidant

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MDA20160122A MD4469C1 (ro) 2016-11-03 2016-11-03 Utilizarea di(µ-S)-bis{(4-aminobenzensulfamid)-cloro-[2-picoliden-4-feniltiosemicarbazidato-(1-)]cupru(II)} în calitate de antioxidant

Publications (2)

Publication Number Publication Date
MD4469B1 true MD4469B1 (ro) 2017-03-31
MD4469C1 MD4469C1 (ro) 2017-10-31

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MDA20160122A MD4469C1 (ro) 2016-11-03 2016-11-03 Utilizarea di(µ-S)-bis{(4-aminobenzensulfamid)-cloro-[2-picoliden-4-feniltiosemicarbazidato-(1-)]cupru(II)} în calitate de antioxidant

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4527B1 (ro) * 2017-06-02 2017-11-30 Государственный Университет Молд0 Utilizarea saliciliden-4-alil-S-metilizotiosemicarbazidaţilor de fier(III) şi cobalt(III) în calitate de antioxidanţi

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2309740C1 (ru) * 2006-08-03 2007-11-10 Исаак Григорьевич Гитлин Антиоксидант для профилактики заболеваний, связанных с окислительным стрессом, способ его получения, содержащий его гранулят и таблетированная или капсулированная форма на его основе
GB2456528B (en) * 2008-01-16 2012-08-22 Pangaea Lab Ltd Antioxidant for use in cosmetic, medicated and pharmaceutical compositions
RU2553428C2 (ru) * 2013-05-08 2015-06-10 Федеральное государственное бюджетное учреждение науки Иркутский институт химии им. А.Е. Фаворского Сибирского отделения Российской академии наук РАН (ИрИХ СО РАН) Способ получения моно- и билигандных комплексных соединений ионов двухвалентных металлов- цинка, меди (ii) и кальция, с дигидрокверцетином, обладающих усиленной антиоксидантной активностью
CN104341438B (zh) * 2014-04-15 2016-06-22 河南理工大学 可形成具有(4，4)-拓扑结构的铜配位化合物及其制备方法与应用
CN105017197B (zh) * 2015-05-29 2017-07-07 华中师范大学 一种缩氨脲类化合物的制备方法和在生物医学方面的应用

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4527B1 (ro) * 2017-06-02 2017-11-30 Государственный Университет Молд0 Utilizarea saliciliden-4-alil-S-metilizotiosemicarbazidaţilor de fier(III) şi cobalt(III) în calitate de antioxidanţi

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Publication number Publication date
MD4469C1 (ro) 2017-10-31

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FG4A Patent for invention issued
KA4A Patent for invention lapsed due to non-payment of fees (with right of restoration)
MM4A Patent for invention definitely lapsed due to non-payment of fees