MD4215B1 - Inhibitor of human myeloid leukemia based on N-(4-(5-(pyridin-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)-2-(pyridin-2-ylmethylen)-hydrazinecarbothioamide - Google Patents

Inhibitor of human myeloid leukemia based on N-(4-(5-(pyridin-2-yl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)-2-(pyridin-2-ylmethylen)-hydrazinecarbothioamide

Info

Publication number
MD4215B1
MD4215B1 MD20120059A MD20120059A MD4215B1 MD 4215 B1 MD4215 B1 MD 4215B1 MD 20120059 A MD20120059 A MD 20120059A MD 20120059 A MD20120059 A MD 20120059A MD 4215 B1 MD4215 B1 MD 4215B1
Authority
MD
Moldova
Prior art keywords
pyridin
myeloid leukemia
human myeloid
ylmethylen
hydrazinecarbothioamide
Prior art date
Application number
MD20120059A
Other languages
English (en)
Romanian (ro)
Other versions
MD4215C1 (ro
Inventor
Nicanor BARBA
Aurelian Gulea
Ana Popusoi
Angela Jalba
Original Assignee
Univ De Stat Din Moldova
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ De Stat Din Moldova filed Critical Univ De Stat Din Moldova
Priority to MDA20120059A priority Critical patent/MD4215C1/ro
Publication of MD4215B1 publication Critical patent/MD4215B1/mo
Publication of MD4215C1 publication Critical patent/MD4215C1/ro

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  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MDA20120059A 2012-07-09 2012-07-09 Inhibitor al leucemiei mieloide umane în bază de N-(4-(5-(piridin-2-il)-4,5-dihidro-1H-pirazol-3-il)fenil)-2-(piridin-2-ilmetilen)-hidrazincarbotioamidă MD4215C1 (ro)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MDA20120059A MD4215C1 (ro) 2012-07-09 2012-07-09 Inhibitor al leucemiei mieloide umane în bază de N-(4-(5-(piridin-2-il)-4,5-dihidro-1H-pirazol-3-il)fenil)-2-(piridin-2-ilmetilen)-hidrazincarbotioamidă

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MDA20120059A MD4215C1 (ro) 2012-07-09 2012-07-09 Inhibitor al leucemiei mieloide umane în bază de N-(4-(5-(piridin-2-il)-4,5-dihidro-1H-pirazol-3-il)fenil)-2-(piridin-2-ilmetilen)-hidrazincarbotioamidă

Publications (2)

Publication Number Publication Date
MD4215B1 true MD4215B1 (en) 2013-04-30
MD4215C1 MD4215C1 (ro) 2013-11-30

Family

ID=48227600

Family Applications (1)

Application Number Title Priority Date Filing Date
MDA20120059A MD4215C1 (ro) 2012-07-09 2012-07-09 Inhibitor al leucemiei mieloide umane în bază de N-(4-(5-(piridin-2-il)-4,5-dihidro-1H-pirazol-3-il)fenil)-2-(piridin-2-ilmetilen)-hidrazincarbotioamidă

Country Status (1)

Country Link
MD (1) MD4215C1 (mo)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4349C1 (ro) * 2014-06-23 2015-12-31 Государственный Университет Молд0 Compusul N-(3-metoxifenil)-2-(piridin-2-ilmetilen)-hidrazincarbotioamidă - inhibitor al proliferării celulelor MeW-164 ale melanomului uman
MD4520B1 (ro) * 2016-12-16 2017-10-31 Государственный Университет Молд0 N-(4-butoxifenil)-2-(piridin-2-ilmetiliden)hidrazincarbotioamida în calitate de inhibitor al proliferării celulelor T-47D ale cancerului mamar

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4407C1 (ro) * 2015-04-29 2016-10-31 Государственный Университет Молд0 Inhibitor al celulelor HL-60 ale leucemiei umane mieloide în baza hidratului clorurii de bis[N-(prop-2-en-1-il)-2-(piridin-2-ilmetiliden)-hidrazincarbotioamid]-nichel(II)
MD4393C1 (ro) * 2015-09-04 2016-08-31 Государственный Университет Молд0 Inhibitor al celulelor HL-60 ale leucemiei umane mieloide în baza nitrato-[N′-(1-piridin-2-ilmetiliden)morfolin-4-carbotiohidrazido(1-)]cupru
MD4434C1 (ro) * 2015-10-09 2017-04-30 Государственный Университет Молд0 Utilizarea N'-[1-(2-piridil)etiliden]morfolin-4-carbotiohidrazidei în calitate de inhibitor al proliferării celulelor HL-60 ale leucemiei mieloide umane

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5565491A (en) * 1994-01-31 1996-10-15 Bristol-Myers Squibb Company Use of phosphotyrosine phospatase inhibitors for controlling cellular proliferation
MD2786G2 (ro) * 2004-05-11 2006-02-28 Государственный Университет Молд0 Inhibitori ai leucemiei umane mieloide în bază de combinaţii coordinative heteronucleare ale cobaltului(III) si bismutului(III)
MD2851G2 (ro) * 2004-08-12 2006-04-30 Государственный Университет Молд0 Inhibitor al leucemiei umane mieloide în baza tricloracetatului dimeric asimetric de cobalt
MD3098G2 (ro) * 2006-01-03 2007-02-28 Государственный Университет Молд0 Dihidrat de di(?-Ofenoxi)-di[N-(2-oxi-1-benzal)-N1-?-oxifuralhidrazino(2-)cupru] cu proprietăţi de inhibitor al leucemiei mieloide umane
MD3655G2 (ro) * 2007-09-03 2009-02-28 Государственный Университет Молд0 Inhibitor al leucemiei mieloide umane în bază de bis(2-hidroxi-8-fenil-triciclo/7.3.1.0.2,7/tridecan-13-on-tiosemicarbazonato)cupru
CN101842362A (zh) * 2007-09-27 2010-09-22 沃尔特及伊莱萨霍尔医学研究院 苯并噻唑化合物
MD3890G2 (ro) * 2008-09-08 2009-12-31 Государственный Университет Молд0 Inhibitori ai leucemiei mieloide umane în baza compuşilor coordinativi ai cuprului(II) cu salicilidentiosemicarbazide
MD4126C1 (ro) * 2010-11-15 2012-04-30 Государственный Университет Молд0 N,N'-[4,4'-(perfluoro-1,4-fenilendioxi)-bis(4,1-fenilen)]-bis[2-(piridin-2-ilmetilen)hidrazincarbotioamidă] şi utilizarea ei în calitate de inhibitor al proliferării celulelor LNCaP ale cancerului prostatei

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD4349C1 (ro) * 2014-06-23 2015-12-31 Государственный Университет Молд0 Compusul N-(3-metoxifenil)-2-(piridin-2-ilmetilen)-hidrazincarbotioamidă - inhibitor al proliferării celulelor MeW-164 ale melanomului uman
MD4520B1 (ro) * 2016-12-16 2017-10-31 Государственный Университет Молд0 N-(4-butoxifenil)-2-(piridin-2-ilmetiliden)hidrazincarbotioamida în calitate de inhibitor al proliferării celulelor T-47D ale cancerului mamar

Also Published As

Publication number Publication date
MD4215C1 (ro) 2013-11-30

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Legal Events

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FG4A Patent for invention issued
KA4A Patent for invention lapsed due to non-payment of fees (with right of restoration)
MM4A Patent for invention definitely lapsed due to non-payment of fees