MD1394Y - Metodă de hemostază endoscopică a hemoragiilor variceale în ciroza hepatică - Google Patents
Metodă de hemostază endoscopică a hemoragiilor variceale în ciroza hepatică Download PDFInfo
- Publication number
- MD1394Y MD1394Y MDS20190069A MD1394Y MD 1394 Y MD1394 Y MD 1394Y MD S20190069 A MDS20190069 A MD S20190069A MD 1394 Y MD1394 Y MD 1394Y
- Authority
- MD
- Moldova
- Prior art keywords
- solution
- liver cirrhosis
- endoscopic hemostasis
- aprotinin
- thrombin
- Prior art date
Links
- 230000000740 bleeding effect Effects 0.000 title abstract 2
- 208000019425 cirrhosis of liver Diseases 0.000 title abstract 2
- 230000023597 hemostasis Effects 0.000 title abstract 2
- 108010039627 Aprotinin Proteins 0.000 abstract 2
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 abstract 2
- 108010049003 Fibrinogen Proteins 0.000 abstract 2
- 102000008946 Fibrinogen Human genes 0.000 abstract 2
- 108090000190 Thrombin Proteins 0.000 abstract 2
- 206010046996 Varicose vein Diseases 0.000 abstract 2
- 229960004405 aprotinin Drugs 0.000 abstract 2
- 229910001628 calcium chloride Inorganic materials 0.000 abstract 2
- 239000001110 calcium chloride Substances 0.000 abstract 2
- 229940012952 fibrinogen Drugs 0.000 abstract 2
- ZPNFWUPYTFPOJU-LPYSRVMUSA-N iniprol Chemical compound C([C@H]1C(=O)NCC(=O)NCC(=O)N[C@H]2CSSC[C@H]3C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@H](C(N[C@H](C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=4C=CC(O)=CC=4)C(=O)N[C@@H](CC=4C=CC=CC=4)C(=O)N[C@@H](CC=4C=CC(O)=CC=4)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC=4C=CC=CC=4)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC2=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CSSC[C@H](NC(=O)[C@H](CC=2C=CC=CC=2)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]2N(CCC2)C(=O)[C@@H](N)CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N2[C@@H](CCC2)C(=O)N2[C@@H](CCC2)C(=O)N[C@@H](CC=2C=CC(O)=CC=2)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N2[C@@H](CCC2)C(=O)N3)C(=O)NCC(=O)NCC(=O)N[C@@H](C)C(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@H](C(=O)N1)C(C)C)[C@@H](C)O)[C@@H](C)CC)=O)[C@@H](C)CC)C1=CC=C(O)C=C1 ZPNFWUPYTFPOJU-LPYSRVMUSA-N 0.000 abstract 2
- 229960004072 thrombin Drugs 0.000 abstract 2
- 108010080379 Fibrin Tissue Adhesive Proteins 0.000 abstract 1
- 206010016654 Fibrosis Diseases 0.000 abstract 1
- NNJVILVZKWQKPM-UHFFFAOYSA-N Lidocaine Chemical compound CCN(CC)CC(=O)NC1=C(C)C=CC=C1C NNJVILVZKWQKPM-UHFFFAOYSA-N 0.000 abstract 1
- 229960002713 calcium chloride Drugs 0.000 abstract 1
- VAAUVRVFOQPIGI-SPQHTLEESA-N ceftriaxone Chemical compound S([C@@H]1[C@@H](C(N1C=1C(O)=O)=O)NC(=O)\C(=N/OC)C=2N=C(N)SC=2)CC=1CSC1=NC(=O)C(=O)NN1C VAAUVRVFOQPIGI-SPQHTLEESA-N 0.000 abstract 1
- 229960004755 ceftriaxone Drugs 0.000 abstract 1
- 230000007882 cirrhosis Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229960004194 lidocaine Drugs 0.000 abstract 1
- 210000004185 liver Anatomy 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 208000027185 varicose disease Diseases 0.000 abstract 1
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Invenţia se referă la medicină, în special la hemostaza endoscopică a hemoragiilor din variceesofago-gastrice în caz de ciroză hepatică.Esenţa invenţiei constă în aceea că endoscopic se injectează în lumenul varicelui o soluţie de ceftriaxon 0,5...1,0 g, dizolvat în 5,0...10,0 ml solutie de lidocaină de 2%, apoi se introduc concomitent componentele unui adeziv fibrinic şi anume, primul component include o soluţie de fibrinogen, iar al doilea component include un amestec de soluţii de aprotinină, trombină si clorură de Ca+2, în următorul raport al componentelor la 1 ml:
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDS20190069A MD1394Z (ro) | 2019-07-10 | 2019-07-10 | Metodă de hemostază endoscopică a hemoragiilor variceale în ciroza hepatică |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDS20190069A MD1394Z (ro) | 2019-07-10 | 2019-07-10 | Metodă de hemostază endoscopică a hemoragiilor variceale în ciroza hepatică |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD1394Y true MD1394Y (ro) | 2019-11-30 |
| MD1394Z MD1394Z (ro) | 2020-06-30 |
Family
ID=68732612
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDS20190069A MD1394Z (ro) | 2019-07-10 | 2019-07-10 | Metodă de hemostază endoscopică a hemoragiilor variceale în ciroza hepatică |
Country Status (1)
| Country | Link |
|---|---|
| MD (1) | MD1394Z (ro) |
-
2019
- 2019-07-10 MD MDS20190069A patent/MD1394Z/ro not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| MD1394Z (ro) | 2020-06-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG9Y | Short term patent issued | ||
| KA4Y | Short-term patent lapsed due to non-payment of fees (with right of restoration) |