MD1018Z - Метод лечения приступа мигрени у пациентов с эпизодической мигренью - Google Patents
Метод лечения приступа мигрени у пациентов с эпизодической мигренью Download PDFInfo
- Publication number
- MD1018Z MD1018Z MDS20150138A MDS20150138A MD1018Z MD 1018 Z MD1018 Z MD 1018Z MD S20150138 A MDS20150138 A MD S20150138A MD S20150138 A MDS20150138 A MD S20150138A MD 1018 Z MD1018 Z MD 1018Z
- Authority
- MD
- Moldova
- Prior art keywords
- migraine
- patients
- attack
- episodic
- timolol
- Prior art date
Links
- 208000019695 Migraine disease Diseases 0.000 title claims abstract description 22
- 206010027599 migraine Diseases 0.000 title claims abstract description 22
- 230000001667 episodic effect Effects 0.000 title claims abstract description 7
- 238000000034 method Methods 0.000 title claims description 9
- TWBNMYSKRDRHAT-RCWTXCDDSA-N (S)-timolol hemihydrate Chemical compound O.CC(C)(C)NC[C@H](O)COC1=NSN=C1N1CCOCC1.CC(C)(C)NC[C@H](O)COC1=NSN=C1N1CCOCC1 TWBNMYSKRDRHAT-RCWTXCDDSA-N 0.000 claims abstract description 10
- 229960004605 timolol Drugs 0.000 claims abstract description 10
- 239000006196 drop Substances 0.000 claims abstract description 7
- 239000003889 eye drop Substances 0.000 claims abstract description 7
- 229940012356 eye drops Drugs 0.000 claims abstract description 7
- 229960004324 betaxolol Drugs 0.000 claims abstract description 4
- NWIUTZDMDHAVTP-UHFFFAOYSA-N betaxolol Chemical compound C1=CC(OCC(O)CNC(C)C)=CC=C1CCOCC1CC1 NWIUTZDMDHAVTP-UHFFFAOYSA-N 0.000 claims abstract description 4
- 239000003814 drug Substances 0.000 abstract description 5
- 206010019233 Headaches Diseases 0.000 description 6
- 231100000869 headache Toxicity 0.000 description 6
- KRQUFUKTQHISJB-YYADALCUSA-N 2-[(E)-N-[2-(4-chlorophenoxy)propoxy]-C-propylcarbonimidoyl]-3-hydroxy-5-(thian-3-yl)cyclohex-2-en-1-one Chemical compound CCC\C(=N/OCC(C)OC1=CC=C(Cl)C=C1)C1=C(O)CC(CC1=O)C1CCCSC1 KRQUFUKTQHISJB-YYADALCUSA-N 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 230000000007 visual effect Effects 0.000 description 3
- 208000000060 Migraine with aura Diseases 0.000 description 2
- 206010039729 Scotoma Diseases 0.000 description 2
- 230000003247 decreasing effect Effects 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 206010067484 Adverse reaction Diseases 0.000 description 1
- 206010003840 Autonomic nervous system imbalance Diseases 0.000 description 1
- 208000030453 Drug-Related Side Effects and Adverse reaction Diseases 0.000 description 1
- 208000010412 Glaucoma Diseases 0.000 description 1
- 206010027603 Migraine headaches Diseases 0.000 description 1
- 206010028813 Nausea Diseases 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 206010054956 Phonophobia Diseases 0.000 description 1
- 206010034960 Photophobia Diseases 0.000 description 1
- 206010034962 Photopsia Diseases 0.000 description 1
- 208000037048 Prodromal Symptoms Diseases 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000006838 adverse reaction Effects 0.000 description 1
- 210000001742 aqueous humor Anatomy 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 102000012740 beta Adrenergic Receptors Human genes 0.000 description 1
- 108010079452 beta Adrenergic Receptors Proteins 0.000 description 1
- 239000002876 beta blocker Substances 0.000 description 1
- 229940097320 beta blocking agent Drugs 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 210000004240 ciliary body Anatomy 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 230000003447 ipsilateral effect Effects 0.000 description 1
- 230000002045 lasting effect Effects 0.000 description 1
- 230000008693 nausea Effects 0.000 description 1
- 230000000926 neurological effect Effects 0.000 description 1
- 229910000065 phosphene Inorganic materials 0.000 description 1
- 230000003449 preventive effect Effects 0.000 description 1
- 230000000306 recurrent effect Effects 0.000 description 1
- 230000009897 systematic effect Effects 0.000 description 1
- 229940084765 timolol ophthalmic solution Drugs 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Изобретение относится к медицине, в частности к неврологии и может быть использовано для лечения приступа мигрени у пациентов с эпизодической мигренью.Сущность изобретения состоит в том, что при появлении первых признаков приступа мигрени закапывают в оба глаза глазные капли тимолол 0,5% или бетаксолол 0,25%, по одной капле 1…3 раза, через каждые 15 мин.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDS20150138A MD1018Z (ru) | 2015-10-01 | 2015-10-01 | Метод лечения приступа мигрени у пациентов с эпизодической мигренью |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MDS20150138A MD1018Z (ru) | 2015-10-01 | 2015-10-01 | Метод лечения приступа мигрени у пациентов с эпизодической мигренью |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MD1018Y MD1018Y (ru) | 2016-03-31 |
| MD1018Z true MD1018Z (ru) | 2016-10-31 |
Family
ID=55646057
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MDS20150138A MD1018Z (ru) | 2015-10-01 | 2015-10-01 | Метод лечения приступа мигрени у пациентов с эпизодической мигренью |
Country Status (1)
| Country | Link |
|---|---|
| MD (1) | MD1018Z (ru) |
-
2015
- 2015-10-01 MD MDS20150138A patent/MD1018Z/ru not_active IP Right Cessation
Non-Patent Citations (1)
| Title |
|---|
| Etemadifar M., Abedi M. The preventive Role of Topical Timolol in Treatment of Migraine Headaches. Journal of Research in Medical Sciences. 2005, 10, p. 288-291 * |
Also Published As
| Publication number | Publication date |
|---|---|
| MD1018Y (ru) | 2016-03-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG9Y | Short term patent issued | ||
| KA4Y | Short-term patent lapsed due to non-payment of fees (with right of restoration) |