MC2072A1 - Procede pour la preparation d'une proteine hybride - Google Patents

Procede pour la preparation d'une proteine hybride

Info

Publication number
MC2072A1
MC2072A1 MC892075A MC2075A MC2072A1 MC 2072 A1 MC2072 A1 MC 2072A1 MC 892075 A MC892075 A MC 892075A MC 2075 A MC2075 A MC 2075A MC 2072 A1 MC2072 A1 MC 2072A1
Authority
MC
Monaco
Prior art keywords
preparation
hybrid protein
hybrid
protein
Prior art date
Application number
MC892075A
Other languages
English (en)
Inventor
W Ju Grace
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MC2072A1 publication Critical patent/MC2072A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/55—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
MC892075A 1988-11-17 1989-11-15 Procede pour la preparation d'une proteine hybride MC2072A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27235688A 1988-11-17 1988-11-17

Publications (1)

Publication Number Publication Date
MC2072A1 true MC2072A1 (fr) 1990-10-03

Family

ID=23039446

Family Applications (1)

Application Number Title Priority Date Filing Date
MC892075A MC2072A1 (fr) 1988-11-17 1989-11-15 Procede pour la preparation d'une proteine hybride

Country Status (13)

Country Link
EP (1) EP0369316A3 (fr)
JP (1) JPH02273193A (fr)
AU (1) AU4474589A (fr)
CA (1) CA2002854A1 (fr)
DK (1) DK570589A (fr)
FI (1) FI895456A0 (fr)
HU (1) HUT52154A (fr)
IL (1) IL92316A0 (fr)
MC (1) MC2072A1 (fr)
NO (1) NO894573L (fr)
PT (1) PT92335A (fr)
YU (1) YU219289A (fr)
ZA (1) ZA898139B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69019609T2 (de) * 1989-07-07 1995-11-30 Takeda Chemical Industries Ltd Proteine und deren Herstellung.
FR2653020B1 (fr) * 1989-10-17 1993-03-26 Roussel Uclaf Utilisation d'un polypeptide ayant l'activite de l'interleukine 2 humaine pour la preparation de compositions pharmaceutiques destinees au traitement des leucemies.
US5594107A (en) * 1990-08-22 1997-01-14 University Of Saskatchewan Chimeric protein comprising an RTX-family cytotoxin and interferon-2 or interferon
US5273889A (en) * 1990-08-22 1993-12-28 University Of Saskatchewan Gamma-iterferon-leukotoxin gene fusions and uses thereof
US5238823A (en) * 1990-08-22 1993-08-24 Veterinary Infectious Disease Organization Interleukin-2-leukotoxin gene fusions and uses thereof
DE69132925T2 (de) * 1990-08-29 2002-10-10 Ct Hospitalier Regional De Nan An stabile proteinkernstruktur gebundene proteinpolyliganden
US5571507A (en) * 1992-02-25 1996-11-05 Seragen, Inc. Methods of treating diabetes

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ210634A (en) * 1983-12-23 1989-05-29 Hoffmann La Roche Purification of recombinant human interleukin - 2; pharmaceutical compositions
DE3537461A1 (de) * 1985-10-22 1987-04-23 Hoechst Ag Derivat des interleukin-2, seine herstellung und verwendung
US4892827A (en) * 1986-09-24 1990-01-09 The United States Of America As Represented By The Department Of Health And Human Services Recombinant pseudomonas exotoxins: construction of an active immunotoxin with low side effects

Also Published As

Publication number Publication date
IL92316A0 (en) 1990-07-26
YU219289A (en) 1991-10-31
DK570589A (da) 1990-05-18
AU4474589A (en) 1990-05-24
EP0369316A2 (fr) 1990-05-23
CA2002854A1 (fr) 1990-05-17
DK570589D0 (da) 1989-11-14
HU895908D0 (en) 1990-02-28
FI895456A0 (fi) 1989-11-16
NO894573L (no) 1990-05-18
HUT52154A (en) 1990-06-28
JPH02273193A (ja) 1990-11-07
EP0369316A3 (fr) 1990-11-22
NO894573D0 (no) 1989-11-16
ZA898139B (en) 1990-08-29
PT92335A (pt) 1990-05-31

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