MC1695A1 - Procedes de preparation de nouveaux composes et de formes pharmaceutiques les contenant - Google Patents

Procedes de preparation de nouveaux composes et de formes pharmaceutiques les contenant

Info

Publication number
MC1695A1
MC1695A1 MC851792A MC1792A MC1695A1 MC 1695 A1 MC1695 A1 MC 1695A1 MC 851792 A MC851792 A MC 851792A MC 1792 A MC1792 A MC 1792A MC 1695 A1 MC1695 A1 MC 1695A1
Authority
MC
Monaco
Prior art keywords
processes
preparation
new compounds
pharmaceutical forms
forms containing
Prior art date
Application number
MC851792A
Other languages
English (en)
French (fr)
Inventor
Geoffrey Allan
Donald Bull
George-William Hardy
Grahame-Roy Lee
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of MC1695A1 publication Critical patent/MC1695A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
MC851792A 1984-09-01 1985-08-22 Procedes de preparation de nouveaux composes et de formes pharmaceutiques les contenant MC1695A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848422165A GB8422165D0 (en) 1984-09-01 1984-09-01 Compounds

Publications (1)

Publication Number Publication Date
MC1695A1 true MC1695A1 (fr) 1986-07-18

Family

ID=10566163

Family Applications (1)

Application Number Title Priority Date Filing Date
MC851792A MC1695A1 (fr) 1984-09-01 1985-08-22 Procedes de preparation de nouveaux composes et de formes pharmaceutiques les contenant

Country Status (16)

Country Link
EP (1) EP0174162A3 (xx)
JP (1) JPS6183198A (xx)
KR (1) KR860002501A (xx)
AU (1) AU581455B2 (xx)
CS (1) CS621585A2 (xx)
DD (1) DD236522A5 (xx)
DK (1) DK396885A (xx)
ES (6) ES8703418A1 (xx)
FI (1) FI853336L (xx)
GB (1) GB8422165D0 (xx)
GR (1) GR852113B (xx)
HU (1) HUT39190A (xx)
MC (1) MC1695A1 (xx)
PL (3) PL255192A1 (xx)
PT (1) PT81055B (xx)
ZA (1) ZA856672B (xx)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL81704A0 (en) * 1986-02-28 1987-09-16 Wellcome Found Naphthyl and indolyl derivatives,their preparation and pharmaceutical compositions containing them
HUT44579A (en) * 1986-02-28 1988-03-28 Wellcome Found Process for preparing novel compounds and pharmaceuticals comprising them
US4927807A (en) * 1987-10-06 1990-05-22 Abbott Laboratories Glaucoma treatment
US5346887A (en) * 1987-10-06 1994-09-13 Abbott Laboratories Glaucoma treatment
US5036051A (en) * 1987-10-06 1991-07-30 Abbott Laboratories Glaucoma treatment
US5187183A (en) * 1988-06-15 1993-02-16 Brigham & Women's Hospital S-nitroso derivatives of ACE inhibitors and the use thereof
US5025001A (en) * 1988-06-15 1991-06-18 Brigham And Women's Hospital S-nitroso derivatives of ACE inhibitors and the use thereof
US5356890A (en) * 1988-06-15 1994-10-18 Brigham And Women's Hospital S-nitroso derivatives of ace inhibitors and the use thereof
US5059589A (en) * 1988-09-08 1991-10-22 Abbott Laboratories Glaucoma treatment
US4916129A (en) * 1989-01-19 1990-04-10 E. I. Du Pont De Nemours And Company Combination β-blocking/angiotensin II blocking antihypertensives
US11229746B2 (en) 2006-06-22 2022-01-25 Excelsior Medical Corporation Antiseptic cap
US9259535B2 (en) 2006-06-22 2016-02-16 Excelsior Medical Corporation Antiseptic cap equipped syringe
US9078992B2 (en) 2008-10-27 2015-07-14 Pursuit Vascular, Inc. Medical device for applying antimicrobial to proximal end of catheter
US10166381B2 (en) 2011-05-23 2019-01-01 Excelsior Medical Corporation Antiseptic cap
WO2013009998A2 (en) 2011-07-12 2013-01-17 Pursuit Vascular, Inc. Device for delivery of antimicrobial agent into trans-dermal catheter
EP3137122B1 (en) 2014-05-02 2019-09-04 Excelsior Medical Corporation Strip package for antiseptic cap
JP6822978B2 (ja) 2015-05-08 2021-01-27 アイシーユー・メディカル・インコーポレーテッド 治療薬のエミッタを受け入れるように構成された医療用コネクタ
CA3040277A1 (en) 2016-10-14 2018-04-19 Icu Medical, Inc. Sanitizing caps for medical connectors
WO2018204206A2 (en) 2017-05-01 2018-11-08 Icu Medical, Inc. Medical fluid connectors and methods for providing additives in medical fluid lines
US11534595B2 (en) 2018-11-07 2022-12-27 Icu Medical, Inc. Device for delivering an antimicrobial composition into an infusion device
US11400195B2 (en) 2018-11-07 2022-08-02 Icu Medical, Inc. Peritoneal dialysis transfer set with antimicrobial properties
US11541220B2 (en) 2018-11-07 2023-01-03 Icu Medical, Inc. Needleless connector with antimicrobial properties
US11541221B2 (en) 2018-11-07 2023-01-03 Icu Medical, Inc. Tubing set with antimicrobial properties
US11517732B2 (en) 2018-11-07 2022-12-06 Icu Medical, Inc. Syringe with antimicrobial properties
AU2019384564B2 (en) 2018-11-21 2023-11-23 Icu Medical, Inc. Antimicrobial device comprising a cap with ring and insert
CA3204371A1 (en) 2020-12-07 2022-06-16 Icu Medical, Inc. Peritoneal dialysis caps, systems and methods

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3705907A (en) * 1970-02-19 1972-12-12 Sandoz Ltd 4-(2-hydroxy)-3-aminopropoxy)-indole derivatives
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
FR2503155A2 (fr) * 1980-10-02 1982-10-08 Science Union & Cie Nouveaux imino diacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
EP0046953B1 (de) * 1980-08-30 1989-12-06 Hoechst Aktiengesellschaft Aminosäurederivate, Verfahren zu ihrer Herstellung, diese enthaltende Mittel und deren Verwendung
EP0048159A3 (en) * 1980-09-17 1982-05-12 University Of Miami Novel carboxyalkyl peptides and thioethers and ethers of peptides as antihypertensive agents
US4344949A (en) * 1980-10-03 1982-08-17 Warner-Lambert Company Substituted acyl derivatives of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids
US4462943A (en) * 1980-11-24 1984-07-31 E. R. Squibb & Sons, Inc. Carboxyalkyl amino acid derivatives of various substituted prolines
EP0080822A1 (en) * 1981-11-27 1983-06-08 Beecham Group Plc Anti-hypertensive prolinol-based peptides
IE55867B1 (en) * 1981-12-29 1991-02-14 Hoechst Ag New derivatives of bicyclic aminoacids,processes for their preparation,agents containing these compounds and their use,and new bicyclic aminoacids as intermediates and processes for their preparation
EP0088350B1 (en) * 1982-03-08 1985-02-20 Schering Corporation Carboxyalkyl dipeptides, processes for their production and pharmaceutical compositions containing them
AU560285B2 (en) * 1982-07-19 1987-04-02 Imperial Chemical Industries Plc Heterocyclyl carbonyl sulphonamides

Also Published As

Publication number Publication date
ES8801311A1 (es) 1987-12-16
DD236522A5 (de) 1986-06-11
ES553610A0 (es) 1988-01-01
ES553612A0 (es) 1987-12-16
HUT39190A (en) 1986-08-28
PL265522A1 (en) 1988-05-12
PT81055B (en) 1987-07-02
ES8801310A1 (es) 1988-01-01
CS621585A2 (en) 1989-08-14
FI853336L (fi) 1986-03-02
AU581455B2 (en) 1989-02-23
EP0174162A3 (en) 1988-07-27
ES8703418A1 (es) 1987-02-16
EP0174162A2 (en) 1986-03-12
ZA856672B (en) 1987-05-27
DK396885D0 (da) 1985-08-30
GB8422165D0 (en) 1984-10-03
KR860002501A (ko) 1986-04-26
ES553614A0 (es) 1988-02-16
FI853336A0 (fi) 1985-08-30
ES553613A0 (es) 1988-01-01
ES8801672A1 (es) 1988-02-16
ES546595A0 (es) 1987-02-16
ES8801312A1 (es) 1987-12-16
ES8801313A1 (es) 1988-01-01
AU4693285A (en) 1986-03-06
PL255192A1 (en) 1987-09-21
PT81055A (en) 1985-09-01
DK396885A (da) 1986-03-02
GR852113B (xx) 1985-12-24
ES553611A0 (es) 1987-12-16
JPS6183198A (ja) 1986-04-26
PL265523A1 (en) 1988-02-04

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