MA55388A - Procédé d'obtention d'héparines de faible poids moléculaire par filtration à flux tangentiel - Google Patents

Procédé d'obtention d'héparines de faible poids moléculaire par filtration à flux tangentiel

Info

Publication number
MA55388A
MA55388A MA055388A MA55388A MA55388A MA 55388 A MA55388 A MA 55388A MA 055388 A MA055388 A MA 055388A MA 55388 A MA55388 A MA 55388A MA 55388 A MA55388 A MA 55388A
Authority
MA
Morocco
Prior art keywords
molecular weight
low molecular
flow filtration
tangential flow
weight heparin
Prior art date
Application number
MA055388A
Other languages
English (en)
Inventor
Rodríguez Guillermo Franco
Aduriz Ibon Gutierro
Original Assignee
Farm Rovi Lab Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farm Rovi Lab Sa filed Critical Farm Rovi Lab Sa
Publication of MA55388A publication Critical patent/MA55388A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/10—Heparin; Derivatives thereof
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/145—Ultrafiltration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/16—Feed pretreatment
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D69/00—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor
    • B01D69/02—Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or properties; Manufacturing processes specially adapted therefor characterised by their properties
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • C08B37/0078—Degradation products
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2311/00—Details relating to membrane separation process operations and control
    • B01D2311/04—Specific process operations in the feed stream; Feed pretreatment
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2311/00—Details relating to membrane separation process operations and control
    • B01D2311/26—Further operations combined with membrane separation processes
    • B01D2311/2649—Filtration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2315/00—Details relating to the membrane module operation
    • B01D2315/10—Cross-flow filtration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2315/00—Details relating to the membrane module operation
    • B01D2315/16—Diafiltration
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2325/00—Details relating to properties of membranes
    • B01D2325/20—Specific permeability or cut-off range

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Water Supply & Treatment (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MA055388A 2019-04-26 2020-04-24 Procédé d'obtention d'héparines de faible poids moléculaire par filtration à flux tangentiel MA55388A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES201930373 2019-04-26
CN202010078241 2020-01-23

Publications (1)

Publication Number Publication Date
MA55388A true MA55388A (fr) 2022-01-26

Family

ID=72941056

Family Applications (1)

Application Number Title Priority Date Filing Date
MA055388A MA55388A (fr) 2019-04-26 2020-04-24 Procédé d'obtention d'héparines de faible poids moléculaire par filtration à flux tangentiel

Country Status (18)

Country Link
US (1) US20220112315A1 (fr)
EP (1) EP3943513A4 (fr)
JP (1) JP7550787B2 (fr)
KR (1) KR20220005441A (fr)
AU (1) AU2020263142A1 (fr)
BR (1) BR112021020048A2 (fr)
CA (1) CA3134458C (fr)
CL (1) CL2021002647A1 (fr)
CO (1) CO2021013320A2 (fr)
ES (1) ES2888148B2 (fr)
GE (1) GEP20247598B (fr)
IL (1) IL286931A (fr)
MA (1) MA55388A (fr)
MX (1) MX2021011671A (fr)
PE (1) PE20212330A1 (fr)
SG (1) SG11202111009WA (fr)
WO (1) WO2020216981A1 (fr)
ZA (1) ZA202109022B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2022273722A1 (en) * 2021-05-12 2023-11-02 NexEos Diagnostics, Inc. Methods of manufacturing a high molecular weight heparin compound
CN116284499B (zh) * 2022-07-28 2024-07-23 河北常山生化药业股份有限公司 一种羊源低分子肝素钠的制备方法
CN117946294A (zh) * 2023-11-13 2024-04-30 河北常山凯库得生物技术有限公司 一种节能环保依诺肝素钠的制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3787996T2 (de) 1986-05-16 1994-03-03 Italfarmaco Spa Heparine, frei von E.D.T.A., Fraktionen und Fragmente von Heparin, Verfahren zu deren Herstellung und pharmazeutische Zusammensetzungen, welche diese enthalten.
US5767269A (en) 1996-10-01 1998-06-16 Hamilton Civic Hospitals Research Development Inc. Processes for the preparation of low-affinity, low molecular weight heparins useful as antithrombotics
JP4897991B2 (ja) 1999-07-23 2012-03-14 ラボラトリオス ファルマセウティコス ロビ ソシエダッド アノニマ 超低分子量ヘパリン組成物
ES2161615B1 (es) 1999-07-23 2003-03-16 Rovi Lab Farmaceut Sa Composiciones de heparinas de muy bajo peso molecular.
GB0509433D0 (en) 2005-05-09 2005-06-15 Uni For Milj Og Biovitenskap Method
WO2007084856A2 (fr) 2006-01-13 2007-07-26 Baxter International Inc. Procede de purification de polysaccharides
WO2010111710A1 (fr) 2009-03-27 2010-09-30 Solazyme, Inc. Compositions de polysaccharides microalgaux
CN102050888B (zh) 2010-12-13 2011-12-07 河北常山生化药业股份有限公司 一种依诺肝素钠的制备方法
CN102731683A (zh) * 2012-07-17 2012-10-17 湖北亿诺瑞生物制药有限公司 一种从肝素废液中分离天然低分子肝素的方法
CN103214597B (zh) 2013-05-14 2015-11-11 枣庄赛诺康生化股份有限公司 依诺肝素钠中间体脱色方法
CN103342761B (zh) 2013-07-15 2016-01-06 河北常山生化药业股份有限公司 一种膜分离制备依诺肝素钠工艺
CN103936889A (zh) * 2014-03-19 2014-07-23 苏州英诺凯生物医药科技有限公司 一种使用切向流过滤纯化依诺肝素的方法
CN105985454A (zh) 2015-02-06 2016-10-05 苏州英诺凯生物医药科技有限公司 一种依诺肝素的纯化方法

Also Published As

Publication number Publication date
WO2020216981A1 (fr) 2020-10-29
IL286931A (en) 2021-10-31
ZA202109022B (en) 2023-10-25
AU2020263142A1 (en) 2021-10-28
ES2888148A1 (es) 2021-12-30
JP7550787B2 (ja) 2024-09-13
GEP20247598B (en) 2024-02-26
KR20220005441A (ko) 2022-01-13
US20220112315A1 (en) 2022-04-14
PE20212330A1 (es) 2021-12-14
ES2888148B2 (es) 2022-11-14
MX2021011671A (es) 2021-10-22
CA3134458C (fr) 2023-11-21
JP2022530321A (ja) 2022-06-29
CL2021002647A1 (es) 2022-05-13
EP3943513A4 (fr) 2022-12-21
EP3943513A1 (fr) 2022-01-26
CA3134458A1 (fr) 2020-10-29
SG11202111009WA (en) 2021-11-29
CO2021013320A2 (es) 2022-03-18
BR112021020048A2 (pt) 2021-12-07

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