MA55200A - Composés utiles dans la thérapie du vih - Google Patents

Composés utiles dans la thérapie du vih

Info

Publication number
MA55200A
MA55200A MA055200A MA55200A MA55200A MA 55200 A MA55200 A MA 55200A MA 055200 A MA055200 A MA 055200A MA 55200 A MA55200 A MA 55200A MA 55200 A MA55200 A MA 55200A
Authority
MA
Morocco
Prior art keywords
useful compounds
hiv therapy
hiv
therapy
compounds
Prior art date
Application number
MA055200A
Other languages
English (en)
Inventor
La Rosa Martha Alicia De
John F Miller
B Narasimhulu Naidu
Vicente Samano
David Temelkoff
Emile Johann Velthuisen
Original Assignee
Glaxosmithkline Ip No 2 Ltd
Viiv Healthcare Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Ip No 2 Ltd, Viiv Healthcare Co filed Critical Glaxosmithkline Ip No 2 Ltd
Publication of MA55200A publication Critical patent/MA55200A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/173—Purine radicals with 2-deoxyribosyl as the saccharide radical

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • AIDS & HIV (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MA055200A 2019-03-06 2020-03-04 Composés utiles dans la thérapie du vih MA55200A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201962814316P 2019-03-06 2019-03-06

Publications (1)

Publication Number Publication Date
MA55200A true MA55200A (fr) 2022-01-12

Family

ID=69845479

Family Applications (1)

Application Number Title Priority Date Filing Date
MA055200A MA55200A (fr) 2019-03-06 2020-03-04 Composés utiles dans la thérapie du vih

Country Status (21)

Country Link
US (3) US20230174534A1 (fr)
EP (1) EP3934760A1 (fr)
JP (1) JP2022525013A (fr)
KR (1) KR20210136052A (fr)
CN (1) CN113811360A (fr)
AR (1) AR118240A1 (fr)
AU (1) AU2020231934B2 (fr)
BR (1) BR112021017604A2 (fr)
CA (1) CA3132112A1 (fr)
CL (1) CL2021002309A1 (fr)
CO (1) CO2021012579A2 (fr)
CR (1) CR20210460A (fr)
EA (1) EA202192433A1 (fr)
IL (1) IL285894A (fr)
MA (1) MA55200A (fr)
MX (1) MX2021010700A (fr)
PE (1) PE20212089A1 (fr)
SG (1) SG11202109253SA (fr)
TW (1) TW202102233A (fr)
WO (1) WO2020178767A1 (fr)
ZA (1) ZA202106096B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021116872A1 (fr) 2019-12-09 2021-06-17 Viiv Healthcare Company Compositions pharmaceutiques contenant du cabotégravir
AU2021237718B2 (en) * 2020-03-20 2023-09-21 Gilead Sciences, Inc. Prodrugs of 4'-C-substituted-2-halo-2'-deoxyadenosine nucleosides and methods of making and using the same
US20240317754A1 (en) * 2020-12-30 2024-09-26 Southern University Of Science And Technology Methods and modified nucleosides for treating coronavirus infections
AU2022211056A1 (en) 2021-01-25 2023-07-20 Brii Biosciences, Inc. Combination therapy for hiv with adenosine derivative and capsid inhibitors
WO2022182604A1 (fr) * 2021-02-23 2022-09-01 Viiv Healthcare Company Composés utiles dans le traitement du vih
US20240287124A1 (en) * 2023-01-30 2024-08-29 Merck Sharp & Dohme Llc Prodrugs of 4'-substituted nucleoside reverse transcriptase inhibitors

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB427857A (en) 1934-08-02 1935-05-01 Newsum Sons & Company Ltd H A new or improved system of construction for skeleton structures, particularly vehicle body frames and door frames
US4107288A (en) 1974-09-18 1978-08-15 Pharmaceutical Society Of Victoria Injectable compositions, nanoparticles useful therein, and process of manufacturing same
US5145684A (en) 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
CN1533390A (zh) 2001-03-19 2004-09-29 СҰҩƷ��ҵ��ʽ���� 包含三氮杂螺[5.5]十一烷衍生物作为活性成分的药物组合物
CA2502109C (fr) * 2004-03-24 2010-02-23 Yamasa Corporation Derive de 2-haloadenosine avec substitution sur le carbone en position 4'
WO2015143712A1 (fr) * 2014-03-28 2015-10-01 Merck Sharp & Dohme Corp. Inhibiteurs nucléosidiques substitués en 4' de la transcriptase inverse
EP3203995A4 (fr) * 2014-10-09 2019-05-15 Board of Regents of the University of Nebraska Compositions et méthodes d'administration d'agents thérapeutiques
WO2016066283A1 (fr) * 2014-10-31 2016-05-06 Sandoz Ag Procédé de fluoration amélioré
MX2018003212A (es) * 2015-09-23 2018-07-06 Merck Sharp & Dohme Inhibidores de transcriptasa inversa de nucleosido 4'-substituido y preparaciones de los mismos.
JOP20170038B1 (ar) * 2016-02-12 2021-08-17 Merck Sharp & Dohme مركبات للاستخدام لعلاج عدوى بفيروس hiv والوقاية منه
CN110325542A (zh) * 2016-11-03 2019-10-11 劳伦斯·I·吴 克罗拉滨的前体药物
WO2019171285A1 (fr) * 2018-03-07 2019-09-12 Glaxosmithkline Intellectual Property (No.2) Limited Composés utiles dans la thérapie du vih

Also Published As

Publication number Publication date
CA3132112A1 (fr) 2020-09-10
AU2020231934A1 (en) 2021-09-23
CR20210460A (es) 2022-02-03
ZA202106096B (en) 2023-03-29
US20240182473A1 (en) 2024-06-06
US20220411425A1 (en) 2022-12-29
CL2021002309A1 (es) 2022-09-20
PE20212089A1 (es) 2021-11-04
IL285894A (en) 2021-10-31
EA202192433A1 (ru) 2021-12-28
JP2022525013A (ja) 2022-05-11
US20230174534A1 (en) 2023-06-08
MX2021010700A (es) 2021-10-01
CO2021012579A2 (es) 2021-10-20
CN113811360A (zh) 2021-12-17
EP3934760A1 (fr) 2022-01-12
TW202102233A (zh) 2021-01-16
KR20210136052A (ko) 2021-11-16
SG11202109253SA (en) 2021-09-29
BR112021017604A2 (pt) 2021-11-16
AU2020231934A8 (en) 2022-03-24
AU2020231934B2 (en) 2023-04-20
WO2020178767A1 (fr) 2020-09-10
AR118240A1 (es) 2021-09-22

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