MA47127A - Modulateurs allostériques positifs du récepteur muscarinique de l'acétylcholine m4 - Google Patents
Modulateurs allostériques positifs du récepteur muscarinique de l'acétylcholine m4Info
- Publication number
- MA47127A MA47127A MA047127A MA47127A MA47127A MA 47127 A MA47127 A MA 47127A MA 047127 A MA047127 A MA 047127A MA 47127 A MA47127 A MA 47127A MA 47127 A MA47127 A MA 47127A
- Authority
- MA
- Morocco
- Prior art keywords
- acetylcholin
- muscarinic
- receptor
- positive allosteric
- allosteric modulators
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/28—Cinnolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662435426P | 2016-12-16 | 2016-12-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA47127A true MA47127A (fr) | 2019-10-30 |
Family
ID=62559292
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA047127A MA47127A (fr) | 2016-12-16 | 2017-12-15 | Modulateurs allostériques positifs du récepteur muscarinique de l'acétylcholine m4 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10934276B2 (fr) |
| EP (1) | EP3558946A4 (fr) |
| JP (1) | JP7016471B2 (fr) |
| CN (1) | CN110035995A (fr) |
| BR (1) | BR112018016629A2 (fr) |
| MA (1) | MA47127A (fr) |
| WO (1) | WO2018112312A1 (fr) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20220298141A1 (en) * | 2019-08-21 | 2022-09-22 | Kalvista Pharmaceuticals Limited | Enzyme inhibitors |
| BR112022019077A2 (pt) | 2020-03-26 | 2022-12-27 | Janssen Pharmaceutica Nv | Moduladores da monoacilglicerol lipase |
| EP4447953A1 (fr) | 2021-12-13 | 2024-10-23 | Sage Therapeutics, Inc. | Combinaison de modulateurs positifs du récepteur muscarinique et de modulateurs allostériques positifs de nmda |
| CN114805252B (zh) * | 2022-04-29 | 2024-01-30 | 上海交通大学医学院 | 一种用于精神分裂症认知功能障碍治疗的萘基酰胺类化合物及其制备方法和应用 |
| CN115246842B (zh) * | 2022-06-15 | 2024-05-24 | 深圳湾实验室 | 一类靶向去泛素化酶usp25和usp28的小分子抑制剂 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10156719A1 (de) * | 2001-11-19 | 2003-05-28 | Bayer Ag | Heteroarylcarbonsäureamide |
| WO2006050476A2 (fr) * | 2004-11-03 | 2006-05-11 | Vertex Pharmaceuticals Incorporated | Modulateurs de canaux ioniques et leurs methodes d'utilisation |
| TWI384949B (zh) * | 2006-12-01 | 2013-02-11 | 含有以喹啉化合物或其鹽為有效成分之土壤處理劑或種子處理劑、與使用彼等之植物病害之防治方法 | |
| US20100227884A1 (en) * | 2007-10-15 | 2010-09-09 | Sumitomo Chemical Company, Limited | Amide compounds and plant disease controlling method using same |
| US8901125B2 (en) * | 2012-06-20 | 2014-12-02 | Vanderbilt University | Substituted bicyclic alkoxy pyrazole analogs as allosteric modulators of mGluR5 receptors |
| JP6612874B2 (ja) * | 2014-12-16 | 2019-11-27 | アクソファント サイエンシーズ ゲーエムベーハー | α７−ニコチン性アセチルコリン受容体のアゴニストとしてのジェミナル置換キヌクリジンアミド化合物 |
-
2017
- 2017-12-15 CN CN201780073095.1A patent/CN110035995A/zh active Pending
- 2017-12-15 MA MA047127A patent/MA47127A/fr unknown
- 2017-12-15 JP JP2019532081A patent/JP7016471B2/ja active Active
- 2017-12-15 EP EP17880820.0A patent/EP3558946A4/fr not_active Withdrawn
- 2017-12-15 BR BR112018016629A patent/BR112018016629A2/pt not_active Application Discontinuation
- 2017-12-15 WO PCT/US2017/066608 patent/WO2018112312A1/fr unknown
- 2017-12-15 US US16/469,972 patent/US10934276B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP3558946A1 (fr) | 2019-10-30 |
| EP3558946A4 (fr) | 2020-05-27 |
| US10934276B2 (en) | 2021-03-02 |
| JP2020503302A (ja) | 2020-01-30 |
| US20200079756A1 (en) | 2020-03-12 |
| CN110035995A (zh) | 2019-07-19 |
| WO2018112312A1 (fr) | 2018-06-21 |
| BR112018016629A2 (pt) | 2018-12-26 |
| JP7016471B2 (ja) | 2022-02-07 |
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