MA46524A - Composés de biphényl-sulfonamide destinés au traitement de néphropathies - Google Patents

Composés de biphényl-sulfonamide destinés au traitement de néphropathies

Info

Publication number
MA46524A
MA46524A MA046524A MA46524A MA46524A MA 46524 A MA46524 A MA 46524A MA 046524 A MA046524 A MA 046524A MA 46524 A MA46524 A MA 46524A MA 46524 A MA46524 A MA 46524A
Authority
MA
Morocco
Prior art keywords
nephropathies
biphenyl
treatment
sulfonamide compounds
sulfonamide
Prior art date
Application number
MA046524A
Other languages
English (en)
French (fr)
Inventor
Radko Komers
Alvin Shih
Original Assignee
Retrophin Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Retrophin Inc filed Critical Retrophin Inc
Publication of MA46524A publication Critical patent/MA46524A/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/422Oxazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
MA046524A 2016-10-13 2017-10-13 Composés de biphényl-sulfonamide destinés au traitement de néphropathies MA46524A (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662407860P 2016-10-13 2016-10-13
US201662423079P 2016-11-16 2016-11-16

Publications (1)

Publication Number Publication Date
MA46524A true MA46524A (fr) 2019-08-21

Family

ID=60191503

Family Applications (1)

Application Number Title Priority Date Filing Date
MA046524A MA46524A (fr) 2016-10-13 2017-10-13 Composés de biphényl-sulfonamide destinés au traitement de néphropathies

Country Status (10)

Country Link
US (5) US20190262317A1 (enExample)
EP (1) EP3525784A1 (enExample)
JP (4) JP2019530713A (enExample)
KR (4) KR20230066644A (enExample)
CN (5) CN117017985A (enExample)
AU (3) AU2017341825B2 (enExample)
BR (1) BR112019007576A2 (enExample)
CA (1) CA3039819A1 (enExample)
MA (1) MA46524A (enExample)
WO (1) WO2018071784A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7524167B2 (ja) * 2018-10-04 2024-07-29 トラビア セラピューティクス, インコーポレイテッド Iv型コラーゲン疾患の処置のためのビフェニルスルホンアミド化合物
AU2019404552A1 (en) 2018-12-21 2021-07-15 Travere Therapeutics, Inc. Amorphous sparsentan compositions
CN116173014A (zh) 2019-12-17 2023-05-30 奇努克医疗公司 用阿曲生坦治疗IgA肾病的方法
US20220304979A1 (en) * 2019-12-17 2022-09-29 Chinook Therapeutics, Inc. Methods of reducing disease flares
IL297208A (en) * 2020-04-10 2022-12-01 Chinook Therapeutics Inc Treatment methods for diabetic kidney disease
WO2022246200A1 (en) 2021-05-21 2022-11-24 Travere Therapeutics, Inc. Methods of treating kidney diseases or disorders
KR20240051999A (ko) 2021-08-26 2024-04-22 상하이 한서 바이오메디컬 컴퍼니 리미티드 방향족 고리 함유 생물학적 길항제, 이의 제조 방법 및 용도
JPWO2023127853A1 (enExample) * 2021-12-28 2023-07-06
WO2024073672A1 (en) 2022-09-30 2024-04-04 Travere Therapeutics, Inc. Combination therapy with sparsentan and a sglt2 inhibitor for treating kidney diseases or disorders
JP2025183466A (ja) * 2022-11-11 2025-12-17 株式会社アークメディスン 化合物、エンドセリンa受容体拮抗剤、アンジオテンシンiiタイプ1受容体拮抗剤及び医薬組成物
WO2024249509A1 (en) 2023-05-31 2024-12-05 Travere Therapeutics, Inc. Sparsentan for use in a method of treating iga-mediated diseases
WO2025064688A1 (en) 2023-09-20 2025-03-27 Travere Therapeutics, Inc. Sparsentan for treating immunoglobulin a nephropathy (igan)
CN118666826A (zh) * 2024-08-23 2024-09-20 成都臻拓医药科技有限公司 一种司帕生坦原料药的重结晶纯化方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6638937B2 (en) 1998-07-06 2003-10-28 Bristol-Myers Squibb Co. Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists
IL140622A0 (en) 1998-07-06 2002-02-10 Bristol Myers Squibb Co Biphenyl sufonamide derivatives, pharmaceutical compositions containing the same and methods for the preparation thereof
ATE339417T1 (de) 1999-12-15 2006-10-15 Bristol Myers Squibb Co Biphenyl - sulfonamide als duale angiotensin - endothelin - rezeptor - antagonisten
GB0513553D0 (en) * 2005-07-01 2005-08-10 Fond D Amico Per La Ricerca Su Rab3a
LT3222277T (lt) 2009-03-31 2020-05-11 Ligand Pharmaceuticals Inc. Bifenilsulfonamido endotelino ir angiotenzino ii receptoriaus antagonistas, skirtas glomerulosklerozės ir iga indukuotos nefropatijos gydymui
WO2010135350A2 (en) 2009-05-20 2010-11-25 Pharmacopeia, Llc Biphenyl intermediate compounds and methods for the preparation of a dual angiotensin ii and endothelin a receptor antagonist
US9719981B2 (en) * 2012-08-17 2017-08-01 Father Flanagan's Boys' Home RAC1 inhibitors for the treatment of alport glomerular disease
MA52856B1 (fr) * 2014-04-04 2022-03-31 Pfizer Composés bicycliques hétéroaryle ou aryle fusionnés et leur utilisation en tant qu'inhibiteurs irak4
JP7524167B2 (ja) 2018-10-04 2024-07-29 トラビア セラピューティクス, インコーポレイテッド Iv型コラーゲン疾患の処置のためのビフェニルスルホンアミド化合物

Also Published As

Publication number Publication date
BR112019007576A2 (pt) 2019-07-02
US10864197B2 (en) 2020-12-15
CA3039819A1 (en) 2018-04-19
AU2023219839A1 (en) 2023-09-07
JP2019530713A (ja) 2019-10-24
JP2022137245A (ja) 2022-09-21
KR20190077348A (ko) 2019-07-03
US20200281901A1 (en) 2020-09-10
WO2018071784A1 (en) 2018-04-19
US20190262317A1 (en) 2019-08-29
CN110049764A (zh) 2019-07-23
KR20240162167A (ko) 2024-11-14
AU2025271121A1 (en) 2025-12-18
US20250325522A1 (en) 2025-10-23
CN117085013A (zh) 2023-11-21
CN117017985A (zh) 2023-11-10
US20250325523A1 (en) 2025-10-23
AU2017341825B2 (en) 2023-06-01
US20210196688A1 (en) 2021-07-01
KR20220132030A (ko) 2022-09-29
CN116983302A (zh) 2023-11-03
CN114788823A (zh) 2022-07-26
KR102528435B1 (ko) 2023-05-03
JP2025060754A (ja) 2025-04-10
KR20230066644A (ko) 2023-05-16
EP3525784A1 (en) 2019-08-21
AU2023219839B2 (en) 2025-08-21
JP2022141802A (ja) 2022-09-29
AU2017341825A1 (en) 2019-04-11

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