CA3039819A1 - Biphenyl sulfonamide compounds for the treatment of kidney diseases or disorders - Google Patents
Biphenyl sulfonamide compounds for the treatment of kidney diseases or disorders Download PDFInfo
- Publication number
- CA3039819A1 CA3039819A1 CA3039819A CA3039819A CA3039819A1 CA 3039819 A1 CA3039819 A1 CA 3039819A1 CA 3039819 A CA3039819 A CA 3039819A CA 3039819 A CA3039819 A CA 3039819A CA 3039819 A1 CA3039819 A1 CA 3039819A1
- Authority
- CA
- Canada
- Prior art keywords
- pharmaceutical composition
- subject
- use according
- day
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662407860P | 2016-10-13 | 2016-10-13 | |
| US62/407,860 | 2016-10-13 | ||
| US201662423079P | 2016-11-16 | 2016-11-16 | |
| US62/423,079 | 2016-11-16 | ||
| PCT/US2017/056538 WO2018071784A1 (en) | 2016-10-13 | 2017-10-13 | Biphenyl sulfonamide compounds for the treatment of kidney diseases or disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3039819A1 true CA3039819A1 (en) | 2018-04-19 |
Family
ID=60191503
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3039819A Pending CA3039819A1 (en) | 2016-10-13 | 2017-10-13 | Biphenyl sulfonamide compounds for the treatment of kidney diseases or disorders |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US20190262317A1 (enExample) |
| EP (1) | EP3525784A1 (enExample) |
| JP (4) | JP2019530713A (enExample) |
| KR (4) | KR20190077348A (enExample) |
| CN (5) | CN114788823A (enExample) |
| AU (3) | AU2017341825B2 (enExample) |
| BR (1) | BR112019007576A2 (enExample) |
| CA (1) | CA3039819A1 (enExample) |
| MA (1) | MA46524A (enExample) |
| WO (1) | WO2018071784A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7524167B2 (ja) * | 2018-10-04 | 2024-07-29 | トラビア セラピューティクス， インコーポレイテッド | Ｉｖ型コラーゲン疾患の処置のためのビフェニルスルホンアミド化合物 |
| CN114126712A (zh) * | 2018-12-21 | 2022-03-01 | 特拉维尔治疗公司 | 无定形司巴森坦（sparsentan）组合物 |
| US20220304979A1 (en) * | 2019-12-17 | 2022-09-29 | Chinook Therapeutics, Inc. | Methods of reducing disease flares |
| IL293921A (en) | 2019-12-17 | 2022-08-01 | Chinook Therapeutics Inc | Methods for treating iga kidney disease with atresantan |
| JP2023521169A (ja) * | 2020-04-10 | 2023-05-23 | チヌーク セラピューティクス，インコーポレイテッド | 糖尿病性腎疾患の処置方法 |
| WO2022246200A1 (en) | 2021-05-21 | 2022-11-24 | Travere Therapeutics, Inc. | Methods of treating kidney diseases or disorders |
| KR20240051999A (ko) | 2021-08-26 | 2024-04-22 | 상하이 한서 바이오메디컬 컴퍼니 리미티드 | 방향족 고리 함유 생물학적 길항제, 이의 제조 방법 및 용도 |
| AR128112A1 (es) * | 2021-12-28 | 2024-03-27 | Alchemedicine Inc | Compuesto, antagonista del receptor de angiotensina ii tipo 1 y composición farmacéutica |
| WO2024073672A1 (en) | 2022-09-30 | 2024-04-04 | Travere Therapeutics, Inc. | Combination therapy with sparsentan and a sglt2 inhibitor for treating kidney diseases or disorders |
| JP2025183466A (ja) * | 2022-11-11 | 2025-12-17 | 株式会社アークメディスン | 化合物、エンドセリンａ受容体拮抗剤、アンジオテンシンｉｉタイプ１受容体拮抗剤及び医薬組成物 |
| WO2024249509A1 (en) | 2023-05-31 | 2024-12-05 | Travere Therapeutics, Inc. | Sparsentan for use in a method of treating iga-mediated diseases |
| WO2025064688A1 (en) | 2023-09-20 | 2025-03-27 | Travere Therapeutics, Inc. | Sparsentan for treating immunoglobulin a nephropathy (igan) |
| CN118666826A (zh) * | 2024-08-23 | 2024-09-20 | 成都臻拓医药科技有限公司 | 一种司帕生坦原料药的重结晶纯化方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6638937B2 (en) | 1998-07-06 | 2003-10-28 | Bristol-Myers Squibb Co. | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists |
| KR20010083092A (ko) | 1998-07-06 | 2001-08-31 | 스티븐 비. 데이비스 | 이중 안지오텐신 엔도텔린 수용체 길항제로서의 비페닐술폰아미드 |
| EP1237888B1 (en) | 1999-12-15 | 2006-09-13 | Bristol-Myers Squibb Company | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists |
| GB0513553D0 (en) * | 2005-07-01 | 2005-08-10 | Fond D Amico Per La Ricerca Su | Rab3a |
| EP2413930A4 (en) * | 2009-03-31 | 2012-09-26 | Ligand Pharm Inc | ORAL FORMULATION OF ENDOTHELIN AND ANGIOTENSIN II RECEPTOR AGONISTS BASED ON DIPHENYLSULFONAMIDE TO TREAT HIGH BLOOD PRESSURE AND DIABETIC NEPHROPATHY |
| WO2010135350A2 (en) | 2009-05-20 | 2010-11-25 | Pharmacopeia, Llc | Biphenyl intermediate compounds and methods for the preparation of a dual angiotensin ii and endothelin a receptor antagonist |
| US9719981B2 (en) * | 2012-08-17 | 2017-08-01 | Father Flanagan's Boys' Home | RAC1 inhibitors for the treatment of alport glomerular disease |
| LT3126330T (lt) * | 2014-04-04 | 2019-04-25 | Pfizer Inc. | Bicikliniai kondensuoti heteroarilo arba arilo junginiai, ir jų panaudojimas kaip irak4 inhibitorių |
| JP7524167B2 (ja) | 2018-10-04 | 2024-07-29 | トラビア セラピューティクス， インコーポレイテッド | Ｉｖ型コラーゲン疾患の処置のためのビフェニルスルホンアミド化合物 |
-
2017
- 2017-10-13 CN CN202210441043.8A patent/CN114788823A/zh active Pending
- 2017-10-13 BR BR112019007576A patent/BR112019007576A2/pt not_active Application Discontinuation
- 2017-10-13 EP EP17791821.6A patent/EP3525784A1/en active Pending
- 2017-10-13 CA CA3039819A patent/CA3039819A1/en active Pending
- 2017-10-13 KR KR1020197011413A patent/KR20190077348A/ko not_active Ceased
- 2017-10-13 AU AU2017341825A patent/AU2017341825B2/en active Active
- 2017-10-13 KR KR1020227032048A patent/KR102528435B1/ko active Active
- 2017-10-13 CN CN201780076280.6A patent/CN110049764A/zh active Pending
- 2017-10-13 JP JP2019519669A patent/JP2019530713A/ja not_active Withdrawn
- 2017-10-13 KR KR1020237014470A patent/KR20230066644A/ko not_active Ceased
- 2017-10-13 KR KR1020247036666A patent/KR20240162167A/ko active Pending
- 2017-10-13 CN CN202311093985.2A patent/CN117085013A/zh active Pending
- 2017-10-13 CN CN202311094233.8A patent/CN117017985A/zh active Pending
- 2017-10-13 MA MA046524A patent/MA46524A/fr unknown
- 2017-10-13 WO PCT/US2017/056538 patent/WO2018071784A1/en not_active Ceased
- 2017-10-13 CN CN202311092711.1A patent/CN116983302A/zh active Pending
- 2017-10-13 US US16/340,848 patent/US20190262317A1/en not_active Abandoned
-
2020
- 2020-05-22 US US16/882,206 patent/US10864197B2/en active Active
- 2020-11-12 US US17/096,637 patent/US20210196688A1/en not_active Abandoned
-
2022
- 2022-07-15 JP JP2022113881A patent/JP2022137245A/ja active Pending
- 2022-07-15 JP JP2022113880A patent/JP2022141802A/ja active Pending
-
2023
- 2023-08-22 AU AU2023219839A patent/AU2023219839B2/en active Active
-
2024
- 2024-12-20 JP JP2024225044A patent/JP2025060754A/ja active Pending
-
2025
- 2025-06-27 US US19/253,088 patent/US20250325522A1/en active Pending
- 2025-06-27 US US19/253,120 patent/US20250325523A1/en active Pending
- 2025-11-21 AU AU2025271121A patent/AU2025271121A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR20190077348A (ko) | 2019-07-03 |
| US20210196688A1 (en) | 2021-07-01 |
| US20200281901A1 (en) | 2020-09-10 |
| US20250325523A1 (en) | 2025-10-23 |
| AU2017341825B2 (en) | 2023-06-01 |
| CN116983302A (zh) | 2023-11-03 |
| AU2023219839A1 (en) | 2023-09-07 |
| JP2022141802A (ja) | 2022-09-29 |
| KR20220132030A (ko) | 2022-09-29 |
| EP3525784A1 (en) | 2019-08-21 |
| JP2025060754A (ja) | 2025-04-10 |
| JP2022137245A (ja) | 2022-09-21 |
| AU2023219839B2 (en) | 2025-08-21 |
| CN117017985A (zh) | 2023-11-10 |
| US20250325522A1 (en) | 2025-10-23 |
| JP2019530713A (ja) | 2019-10-24 |
| AU2017341825A1 (en) | 2019-04-11 |
| KR20230066644A (ko) | 2023-05-16 |
| US20190262317A1 (en) | 2019-08-29 |
| BR112019007576A2 (pt) | 2019-07-02 |
| KR102528435B1 (ko) | 2023-05-03 |
| CN117085013A (zh) | 2023-11-21 |
| WO2018071784A1 (en) | 2018-04-19 |
| AU2025271121A1 (en) | 2025-12-18 |
| KR20240162167A (ko) | 2024-11-14 |
| CN114788823A (zh) | 2022-07-26 |
| US10864197B2 (en) | 2020-12-15 |
| MA46524A (fr) | 2019-08-21 |
| CN110049764A (zh) | 2019-07-23 |
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| WO2025064688A1 (en) | Sparsentan for treating immunoglobulin a nephropathy (igan) | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request |
Effective date: 20220914 |
|
| EEER | Examination request |
Effective date: 20220914 |
|
| EEER | Examination request |
Effective date: 20220914 |
|
| EEER | Examination request |
Effective date: 20220914 |
|
| EEER | Examination request |
Effective date: 20220914 |