MA45159A - Polypeptides d'hémagglutinine d'influenza modifiés - Google Patents

Polypeptides d'hémagglutinine d'influenza modifiés

Info

Publication number
MA45159A
MA45159A MA045159A MA45159A MA45159A MA 45159 A MA45159 A MA 45159A MA 045159 A MA045159 A MA 045159A MA 45159 A MA45159 A MA 45159A MA 45159 A MA45159 A MA 45159A
Authority
MA
Morocco
Prior art keywords
influenza hemagglutinin
hemagglutinin polypeptides
modified influenza
modified
polypeptides
Prior art date
Application number
MA045159A
Other languages
English (en)
Inventor
Eliud Oloo
Raymond Oomen
Tod Strugnell
Original Assignee
Sanofi Pasteur Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Pasteur Inc filed Critical Sanofi Pasteur Inc
Publication of MA45159A publication Critical patent/MA45159A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/145Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5258Virus-like particles
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16123Virus like particles [VLP]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
MA045159A 2016-06-03 2017-06-02 Polypeptides d'hémagglutinine d'influenza modifiés MA45159A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201662345502P 2016-06-03 2016-06-03

Publications (1)

Publication Number Publication Date
MA45159A true MA45159A (fr) 2019-04-10

Family

ID=59093612

Family Applications (1)

Application Number Title Priority Date Filing Date
MA045159A MA45159A (fr) 2016-06-03 2017-06-02 Polypeptides d'hémagglutinine d'influenza modifiés

Country Status (14)

Country Link
US (2) US11116832B2 (fr)
EP (1) EP3464327A1 (fr)
JP (3) JP7110119B2 (fr)
KR (2) KR102529010B1 (fr)
CN (2) CN115746107A (fr)
AU (2) AU2017275663B2 (fr)
BR (1) BR112018075078A2 (fr)
CA (1) CA3026094A1 (fr)
EA (1) EA201892385A1 (fr)
IL (1) IL263416A (fr)
MA (1) MA45159A (fr)
MX (1) MX2018014887A (fr)
SG (2) SG10201913650WA (fr)
WO (1) WO2017210592A1 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110106193B (zh) * 2019-05-23 2021-11-12 广州医科大学 一种具有低受体结合活性的高致病性h7n9禽流感病毒抗原及其制备方法
CN110106192B (zh) * 2019-05-23 2021-11-12 广州医科大学 一种具有低受体结合活性的高致病性h7n9禽流感病毒抗原及其制备方法

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4270537A (en) 1979-11-19 1981-06-02 Romaine Richard A Automatic hypodermic syringe
US4596556A (en) 1985-03-25 1986-06-24 Bioject, Inc. Hypodermic injection apparatus
CA1283827C (fr) 1986-12-18 1991-05-07 Giorgio Cirelli Dispositif pour l'injection de formules liquides
GB8704027D0 (en) 1987-02-20 1987-03-25 Owen Mumford Ltd Syringe needle combination
US4940460A (en) 1987-06-19 1990-07-10 Bioject, Inc. Patient-fillable and non-invasive hypodermic injection device assembly
US4790824A (en) 1987-06-19 1988-12-13 Bioject, Inc. Non-invasive hypodermic injection device
US4941880A (en) 1987-06-19 1990-07-17 Bioject, Inc. Pre-filled ampule and non-invasive hypodermic injection device assembly
US5339163A (en) 1988-03-16 1994-08-16 Canon Kabushiki Kaisha Automatic exposure control device using plural image plane detection areas
FR2638359A1 (fr) 1988-11-03 1990-05-04 Tino Dalto Guide de seringue avec reglage de la profondeur de penetration de l'aiguille dans la peau
US5064413A (en) 1989-11-09 1991-11-12 Bioject, Inc. Needleless hypodermic injection device
US5312335A (en) 1989-11-09 1994-05-17 Bioject Inc. Needleless hypodermic injection device
US5190521A (en) 1990-08-22 1993-03-02 Tecnol Medical Products, Inc. Apparatus and method for raising a skin wheal and anesthetizing skin
US5527288A (en) 1990-12-13 1996-06-18 Elan Medical Technologies Limited Intradermal drug delivery device and method for intradermal delivery of drugs
GB9118204D0 (en) 1991-08-23 1991-10-09 Weston Terence E Needle-less injector
SE9102652D0 (sv) 1991-09-13 1991-09-13 Kabi Pharmacia Ab Injection needle arrangement
US5328483A (en) 1992-02-27 1994-07-12 Jacoby Richard M Intradermal injection device with medication and needle guard
US5383851A (en) 1992-07-24 1995-01-24 Bioject Inc. Needleless hypodermic injection device
US5569189A (en) 1992-09-28 1996-10-29 Equidyne Systems, Inc. hypodermic jet injector
US5334144A (en) 1992-10-30 1994-08-02 Becton, Dickinson And Company Single use disposable needleless injector
WO1995024176A1 (fr) 1994-03-07 1995-09-14 Bioject, Inc. Dispositif de remplissage d'ampoule
US5466220A (en) 1994-03-08 1995-11-14 Bioject, Inc. Drug vial mixing and transfer device
US6429199B1 (en) 1994-07-15 2002-08-06 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules for activating dendritic cells
US6207646B1 (en) 1994-07-15 2001-03-27 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
US6194388B1 (en) 1994-07-15 2001-02-27 The University Of Iowa Research Foundation Immunomodulatory oligonucleotides
US6239116B1 (en) 1994-07-15 2001-05-29 University Of Iowa Research Foundation Immunostimulatory nucleic acid molecules
US5599302A (en) 1995-01-09 1997-02-04 Medi-Ject Corporation Medical injection system and method, gas spring thereof and launching device using gas spring
US5730723A (en) 1995-10-10 1998-03-24 Visionary Medical Products Corporation, Inc. Gas pressured needle-less injection device and method
US5893397A (en) 1996-01-12 1999-04-13 Bioject Inc. Medication vial/syringe liquid-transfer apparatus
GB9607549D0 (en) 1996-04-11 1996-06-12 Weston Medical Ltd Spring-powered dispensing device
WO1998037919A1 (fr) 1997-02-28 1998-09-03 University Of Iowa Research Foundation UTILISATION D'ACIDES NUCLEIQUES CONTENANT DES DINUCLEOTIDES CpG NON METHYLES DANS LE TRAITEMENT DES TROUBLES ASSOCIES AUX LIPOPOLYSACCHARIDES
US6406705B1 (en) 1997-03-10 2002-06-18 University Of Iowa Research Foundation Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
US5993412A (en) 1997-05-19 1999-11-30 Bioject, Inc. Injection apparatus
WO1998052581A1 (fr) 1997-05-20 1998-11-26 Ottawa Civic Hospital Loeb Research Institute Vecteurs et procedes destines a l'immunisation et a des protocoles therapeutiques
IT1298087B1 (it) 1998-01-08 1999-12-20 Fiderm S R L Dispositivo per il controllo della profondita' di penetrazione di un ago, in particolare applicabile ad una siringa per iniezioni
US6218371B1 (en) 1998-04-03 2001-04-17 University Of Iowa Research Foundation Methods and products for stimulating the immune system using immunotherapeutic oligonucleotides and cytokines
US7566458B2 (en) 2003-06-16 2009-07-28 Medimmune, Llc Influenza hemagglutinin and neuraminidase variants
EP1851238A4 (fr) 2005-02-24 2008-12-31 Univ Massachusetts Acides nucleiques d'influenza, polypeptides et leurs utilisations
US9439959B2 (en) 2006-07-27 2016-09-13 Takeda Vaccines, Inc. Chimeric influenza virus-like particles
US20120219584A1 (en) * 2009-10-05 2012-08-30 The United States Of America As Represented By The Secretary, Department Of Health Protection against pandemic and seasonal strains of influenza
KR101262300B1 (ko) * 2009-10-06 2013-05-20 헬릭스 주식회사 형질전환 식물 유래의 고병원성 조류독감 바이러스 단백질 백신 및 그 제조방법
EP3431100B1 (fr) 2010-09-14 2021-09-08 University of Pittsburgh- Of the Commonwealth System of Higher Education Antigènes contre la grippe à réactivité large optimisés par ordinateur
JP6169494B2 (ja) 2011-01-31 2017-07-26 ナノセラピューティクス・インコーポレイテッドNanotherapeutics, Inc. インフルエンザaウイルスに対するヘテロサブタイプ免疫応答を誘導するための組換えウイルスベクターおよび方法
RU2612900C2 (ru) 2011-06-20 2017-03-13 Юниверсити Оф Питтсбург - Оф Зе Коммонвэлс Систем Оф Хайе Эдьюкейшн Антигены вируса гриппа h1n1 с широким спектром активности, оптимизированные с применением вычислительных средств
IN2014CN02114A (fr) 2011-09-20 2015-05-29 Sinai School Medicine
CN103957891B (zh) 2011-09-23 2017-01-11 美利坚合众国由健康及人类服务部部长代表 基于流感血凝素蛋白的新颖疫苗
US9504741B2 (en) * 2011-11-23 2016-11-29 Vacdiagn Biotechnology Co., Ltd. Immune methods against influenza viruses and combinatorial vaccines thereof
RU2653756C2 (ru) * 2012-02-07 2018-05-14 Юниверсити Оф Питтсбург - Оф Зе Коммонвэлс Систем Оф Хайе Эдьюкейшн Оптимизированные с помощью компьютера антигены с широким спектром реактивности для вирусов гриппа h3n2
CA2863949C (fr) * 2012-02-13 2021-06-29 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Antigenes largement reactifs optimises par ordinateur pour la grippe h5n1 humaine et aviaire
BR112014023900A2 (pt) * 2012-03-30 2020-11-24 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Polipeptídeo de hemaglutimina de influenza recombinante, molécula de ácido nucleicoisolada, vetor, célula isolada, partícula semelhante ao vírus da influenza, proteína de fusão, composição, e uso
US9309290B2 (en) 2012-11-27 2016-04-12 University of Pittsburgh—of the Commonwealth System of Higher Education Computationally optimized broadly reactive antigens for H1N1 influenza
US20140286981A1 (en) 2013-03-14 2014-09-25 Wisconsin Alumni Research Foundation Broadly reactive mosaic peptide for influenza vaccine
US9975925B2 (en) 2013-08-28 2018-05-22 Glaxosmithkline Biologicals S.A. Influenza antigens and antibodies

Also Published As

Publication number Publication date
EP3464327A1 (fr) 2019-04-10
MX2018014887A (es) 2019-06-06
KR20230061583A (ko) 2023-05-08
AU2022201514B2 (en) 2024-02-15
WO2017210592A1 (fr) 2017-12-07
US11116832B2 (en) 2021-09-14
JP2022153591A (ja) 2022-10-12
US20200215182A1 (en) 2020-07-09
AU2017275663B2 (en) 2021-12-09
JP7110119B2 (ja) 2022-08-01
CN109563138A (zh) 2019-04-02
BR112018075078A2 (pt) 2019-03-06
JP2020141703A (ja) 2020-09-10
KR20190039065A (ko) 2019-04-10
JP2019525733A (ja) 2019-09-12
US11904012B2 (en) 2024-02-20
EA201892385A1 (ru) 2019-06-28
KR102529010B1 (ko) 2023-05-04
CN115746107A (zh) 2023-03-07
CN109563138B (zh) 2022-09-23
AU2017275663A1 (en) 2018-12-13
AU2022201514A1 (en) 2022-03-24
CA3026094A1 (fr) 2017-12-07
IL263416A (en) 2019-01-31
US20220054623A1 (en) 2022-02-24
SG10201913650WA (en) 2020-03-30
SG11201810758WA (en) 2018-12-28

Similar Documents

Publication Publication Date Title
MA46041A (fr) Anticorps anti-tim -3
DK3666771T3 (da) Lpa-antagonister
DK3529248T3 (da) Farmaceutiske sammensætninger
MA44236A (fr) Anticorps anti-tgfbêta 2
DK3407944T3 (da) Forstøver
MA43705A (fr) Formulation pharmaceutique
DK3463345T3 (da) Farmaceutiske kombinationer
DK3463365T3 (da) Farmaceutisk antifungal formulering
DK3263782T3 (da) Indløbselement
MA45159A (fr) Polypeptides d'hémagglutinine d'influenza modifiés
MA49445A (fr) Buse multiliquide
DK3257589T3 (da) Dyse
DK3343570T3 (da) 68GE/68GA-generator
ITUA20161486A1 (it) Capo d'abbigliamento
IT201700112534A1 (it) Capo d'abbigliamento
UA35447S (uk) Етикетка для фармацевтичного засобу
UA34620S (uk) Іграшка - конструктор «мост»
IT201700090331A1 (it) "lopemide"
ITUA20163709A1 (it) "presentosa3d"
CL2017000619S1 (es) Boquilla
IT201700071679A1 (it) Remembebe'
UA33589S (uk) Оприскувач
UA34486S (uk) Перстень «дая»
UA34207S (uk) Каблучка «кольчуга»
UA34205S (uk) Каблучка «драупнір»