MA43415A - Arnm modifié codant pour une uridine diphosphate glucuronosyltransférase et utilisations associées - Google Patents
Arnm modifié codant pour une uridine diphosphate glucuronosyltransférase et utilisations associéesInfo
- Publication number
- MA43415A MA43415A MA043415A MA43415A MA43415A MA 43415 A MA43415 A MA 43415A MA 043415 A MA043415 A MA 043415A MA 43415 A MA43415 A MA 43415A MA 43415 A MA43415 A MA 43415A
- Authority
- MA
- Morocco
- Prior art keywords
- modified rna
- uridine diphosphate
- rna coding
- associated uses
- diphosphate glucuronosyltransferase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/01—Hexosyltransferases (2.4.1)
- C12Y204/01017—Glucuronosyltransferase (2.4.1.17)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7115—Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/45—Transferases (2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562265174P | 2015-12-09 | 2015-12-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA43415A true MA43415A (fr) | 2018-10-17 |
Family
ID=57758709
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA043415A MA43415A (fr) | 2015-12-09 | 2016-12-09 | Arnm modifié codant pour une uridine diphosphate glucuronosyltransférase et utilisations associées |
Country Status (4)
Country | Link |
---|---|
US (1) | US20190307857A1 (fr) |
EP (1) | EP3386533A1 (fr) |
MA (1) | MA43415A (fr) |
WO (1) | WO2017100562A1 (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2022500444A (ja) * | 2018-09-14 | 2022-01-04 | モダーナティエックス・インコーポレイテッドModernaTX, Inc. | クリグラー−ナジャー症候群の治療のためのウリジン二リン酸グリコシルトランスフェラーゼ1ファミリー、ポリペプチドa1をコードするポリヌクレオチド |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4485045A (en) | 1981-07-06 | 1984-11-27 | Research Corporation | Synthetic phosphatidyl cholines useful in forming liposomes |
US4544545A (en) | 1983-06-20 | 1985-10-01 | Trustees University Of Massachusetts | Liposomes containing modified cholesterol for organ targeting |
US5013556A (en) | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
RS63964B1 (sr) | 2005-08-23 | 2023-03-31 | Univ Pennsylvania | Rnk koja sadrži modifikovane nukleozide i postupci za njenu upotrebu |
EP1962907A2 (fr) | 2005-12-21 | 2008-09-03 | Wyeth a Corporation of the State of Delaware | Formulations de proteines a viscosite reduite et leurs utilisations |
DK3338765T3 (en) | 2009-12-01 | 2019-03-04 | Translate Bio Inc | STEROID DERIVATIVE FOR THE SUPPLY OF MRNA IN HUMANGENETIC DISEASES |
WO2012075040A2 (fr) | 2010-11-30 | 2012-06-07 | Shire Human Genetic Therapies, Inc. | Arnm pour l'utilisation dans le traitement de maladies génétiques humaines |
WO2012129648A1 (fr) | 2011-03-25 | 2012-10-04 | University Of Guelph | Activation d'expression de protéines de vecteurs de virus adéno-associés |
RS63244B1 (sr) | 2011-12-16 | 2022-06-30 | Modernatx Inc | Kompozicije modifikovane mrna |
CA2868391A1 (fr) * | 2012-04-02 | 2013-10-10 | Stephane Bancel | Polynucleotides comprenant du n1-methyl-pseudouracils et methodes pour les preparer |
US20140010861A1 (en) | 2012-04-02 | 2014-01-09 | modeRNA Therapeutics | Modified polynucleotides for the production of proteins associated with human disease |
WO2013185069A1 (fr) | 2012-06-08 | 2013-12-12 | Shire Human Genetic Therapies, Inc. | Administration pulmonaire d'arnm à des cellules cibles autres que pulmonaires |
LT2922554T (lt) | 2012-11-26 | 2022-06-27 | Modernatx, Inc. | Terminaliai modifikuota rnr |
JP6730193B2 (ja) * | 2014-04-25 | 2020-07-29 | ジェネトン | 高ビリルビン血症の処置 |
-
2016
- 2016-12-09 MA MA043415A patent/MA43415A/fr unknown
- 2016-12-09 US US15/781,881 patent/US20190307857A1/en not_active Abandoned
- 2016-12-09 WO PCT/US2016/065814 patent/WO2017100562A1/fr active Application Filing
- 2016-12-09 EP EP16823387.2A patent/EP3386533A1/fr not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
WO2017100562A9 (fr) | 2017-08-03 |
US20190307857A1 (en) | 2019-10-10 |
EP3386533A1 (fr) | 2018-10-17 |
WO2017100562A1 (fr) | 2017-06-15 |
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