MA40065B1 - N, n-bis-2-mercaptoéthyle isophtalamide pour le traitement de la maladie de parkinson - Google Patents
N, n-bis-2-mercaptoéthyle isophtalamide pour le traitement de la maladie de parkinsonInfo
- Publication number
- MA40065B1 MA40065B1 MA40065A MA40065A MA40065B1 MA 40065 B1 MA40065 B1 MA 40065B1 MA 40065 A MA40065 A MA 40065A MA 40065 A MA40065 A MA 40065A MA 40065 B1 MA40065 B1 MA 40065B1
- Authority
- MA
- Morocco
- Prior art keywords
- disease
- parkinson
- bis
- treatment
- mercaptoethyl isophthalamide
- Prior art date
Links
- 208000018737 Parkinson disease Diseases 0.000 title abstract 2
- QZUPTXGVPYNUIT-UHFFFAOYSA-N isophthalamide Chemical compound NC(=O)C1=CC=CC(C(N)=O)=C1 QZUPTXGVPYNUIT-UHFFFAOYSA-N 0.000 title abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 208000023105 Huntington disease Diseases 0.000 abstract 1
- 206010002026 amyotrophic lateral sclerosis Diseases 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
L'invention concerne du n,n-bis-2-mercaptoéthyle isophthalamide, ou un sel pharmaceutiquement acceptable ou un dérivé de celui-ci, à utiliser dans le traitement thérapeutique d'un trouble neurodégénératif de type maladie d'alzheimer, maladie de parkinson, maladie de huntington et/ou sclérose latérale amyotrophique.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1409662.2A GB2526623A (en) | 2014-05-30 | 2014-05-30 | New pharmaceutical use |
PCT/GB2015/051572 WO2015181567A1 (fr) | 2014-05-30 | 2015-05-29 | N, n-bis-2-mercaptoéthyle isophtalamide pour le traitement de maladies neurodégénératives |
Publications (2)
Publication Number | Publication Date |
---|---|
MA40065A MA40065A (fr) | 2021-05-19 |
MA40065B1 true MA40065B1 (fr) | 2021-09-30 |
Family
ID=51214502
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA40065A MA40065B1 (fr) | 2014-05-30 | 2015-05-29 | N, n-bis-2-mercaptoéthyle isophtalamide pour le traitement de la maladie de parkinson |
MA54630A MA54630B1 (fr) | 2014-05-30 | 2020-02-06 | N,n-bis-2-mercaptoéthyle isophtalamide pour le traitement des maladies neurodégénératives |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA54630A MA54630B1 (fr) | 2014-05-30 | 2020-02-06 | N,n-bis-2-mercaptoéthyle isophtalamide pour le traitement des maladies neurodégénératives |
Country Status (16)
Country | Link |
---|---|
US (4) | US20170202791A1 (fr) |
EP (2) | EP3148588B1 (fr) |
CY (1) | CY1124509T1 (fr) |
DK (2) | DK3148588T3 (fr) |
ES (2) | ES2938080T3 (fr) |
FI (1) | FI3903774T3 (fr) |
GB (1) | GB2526623A (fr) |
HR (2) | HRP20230105T1 (fr) |
HU (2) | HUE055575T2 (fr) |
LT (2) | LT3903774T (fr) |
MA (2) | MA40065B1 (fr) |
PL (2) | PL3148588T3 (fr) |
PT (2) | PT3903774T (fr) |
RS (2) | RS63859B1 (fr) |
SI (2) | SI3148588T1 (fr) |
WO (1) | WO2015181567A1 (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB202005057D0 (en) | 2020-04-06 | 2020-05-20 | Emeramed Ltd | New Use |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6586600B2 (en) | 2000-12-06 | 2003-07-01 | University Of Kentucky Research Foundation | Multidentate sulfur-containing ligands |
US8349359B2 (en) * | 2004-11-07 | 2013-01-08 | Your Energy Systems, LLC | Liposomal formulation for oral administration of glutathione (reduced) |
US8950583B2 (en) * | 2008-12-06 | 2015-02-10 | Ermes Medical Company Limited | Method to remove heavy metals from a mammal |
US8575218B2 (en) | 2009-09-28 | 2013-11-05 | The University Of Kentucky Research Foundation | Thiol-containing compounds for the removal of elements from tissues and formulations therefor |
IN2012DN02586A (fr) | 2009-09-28 | 2015-08-28 | Univ Kentucky Res Found | |
US20110237776A1 (en) | 2010-03-25 | 2011-09-29 | Haley Boyd E | Aromatic compounds with sulfur containing ligands |
US8426368B2 (en) | 2010-03-25 | 2013-04-23 | The University Of Kentucky Research Foundation | Method of ameliorating oxidative stress and supplementing the diet |
-
2014
- 2014-05-30 GB GB1409662.2A patent/GB2526623A/en not_active Withdrawn
-
2015
- 2015-05-29 HR HRP20230105TT patent/HRP20230105T1/hr unknown
- 2015-05-29 PL PL15733860T patent/PL3148588T3/pl unknown
- 2015-05-29 SI SI201531710T patent/SI3148588T1/sl unknown
- 2015-05-29 WO PCT/GB2015/051572 patent/WO2015181567A1/fr active Application Filing
- 2015-05-29 RS RS20221189A patent/RS63859B1/sr unknown
- 2015-05-29 PL PL21180847.2T patent/PL3903774T3/pl unknown
- 2015-05-29 EP EP15733860.9A patent/EP3148588B1/fr active Active
- 2015-05-29 DK DK15733860.9T patent/DK3148588T3/da active
- 2015-05-29 RS RS20210852A patent/RS62095B1/sr unknown
- 2015-05-29 HU HUE15733860A patent/HUE055575T2/hu unknown
- 2015-05-29 HU HUE21180847A patent/HUE060927T2/hu unknown
- 2015-05-29 ES ES21180847T patent/ES2938080T3/es active Active
- 2015-05-29 US US15/313,877 patent/US20170202791A1/en not_active Abandoned
- 2015-05-29 PT PT211808472T patent/PT3903774T/pt unknown
- 2015-05-29 PT PT157338609T patent/PT3148588T/pt unknown
- 2015-05-29 LT LTEP21180847.2T patent/LT3903774T/lt unknown
- 2015-05-29 ES ES15733860T patent/ES2882977T3/es active Active
- 2015-05-29 SI SI201531911T patent/SI3903774T1/sl unknown
- 2015-05-29 LT LTEPPCT/GB2015/051572T patent/LT3148588T/lt unknown
- 2015-05-29 EP EP21180847.2A patent/EP3903774B1/fr active Active
- 2015-05-29 MA MA40065A patent/MA40065B1/fr unknown
- 2015-05-29 DK DK21180847.2T patent/DK3903774T3/da active
- 2015-05-29 FI FIEP21180847.2T patent/FI3903774T3/fi active
-
2017
- 2017-11-22 US US15/821,371 patent/US20180250247A1/en not_active Abandoned
-
2020
- 2020-02-06 MA MA54630A patent/MA54630B1/fr unknown
-
2021
- 2021-08-13 HR HRP20211309TT patent/HRP20211309T1/hr unknown
- 2021-09-07 CY CY20211100788T patent/CY1124509T1/el unknown
- 2021-12-22 US US17/558,975 patent/US20220287994A1/en active Pending
-
2022
- 2022-09-27 US US17/953,622 patent/US11628151B2/en active Active
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