LT3903774T - N,n-bis-2-merkaptoetilizoftalamidas, skirtas neurodegeneracinių ligų gydymui - Google Patents
N,n-bis-2-merkaptoetilizoftalamidas, skirtas neurodegeneracinių ligų gydymuiInfo
- Publication number
- LT3903774T LT3903774T LTEP21180847.2T LT21180847T LT3903774T LT 3903774 T LT3903774 T LT 3903774T LT 21180847 T LT21180847 T LT 21180847T LT 3903774 T LT3903774 T LT 3903774T
- Authority
- LT
- Lithuania
- Prior art keywords
- bis
- treatment
- neurodegenerative diseases
- mercaptoethyl isophthalamide
- isophthalamide
- Prior art date
Links
- QZUPTXGVPYNUIT-UHFFFAOYSA-N isophthalamide Chemical compound NC(=O)C1=CC=CC(C(N)=O)=C1 QZUPTXGVPYNUIT-UHFFFAOYSA-N 0.000 title 1
- 230000004770 neurodegeneration Effects 0.000 title 1
- 208000015122 neurodegenerative disease Diseases 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/166—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the carbon of a carboxamide group directly attached to the aromatic ring, e.g. procainamide, procarbazine, metoclopramide, labetalol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/428—Thiazoles condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB1409662.2A GB2526623A (en) | 2014-05-30 | 2014-05-30 | New pharmaceutical use |
Publications (1)
Publication Number | Publication Date |
---|---|
LT3903774T true LT3903774T (lt) | 2023-01-10 |
Family
ID=51214502
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LTEP21180847.2T LT3903774T (lt) | 2014-05-30 | 2015-05-29 | N,n-bis-2-merkaptoetilizoftalamidas, skirtas neurodegeneracinių ligų gydymui |
LTEPPCT/GB2015/051572T LT3148588T (lt) | 2014-05-30 | 2015-05-29 | N,n-bis-2-merkaptoetilizoftalamidas, skirtas parkinsono ligos gydymui |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
LTEPPCT/GB2015/051572T LT3148588T (lt) | 2014-05-30 | 2015-05-29 | N,n-bis-2-merkaptoetilizoftalamidas, skirtas parkinsono ligos gydymui |
Country Status (16)
Country | Link |
---|---|
US (4) | US20170202791A1 (lt) |
EP (2) | EP3148588B1 (lt) |
CY (1) | CY1124509T1 (lt) |
DK (2) | DK3148588T3 (lt) |
ES (2) | ES2938080T3 (lt) |
FI (1) | FI3903774T3 (lt) |
GB (1) | GB2526623A (lt) |
HR (2) | HRP20230105T1 (lt) |
HU (2) | HUE060927T2 (lt) |
LT (2) | LT3903774T (lt) |
MA (2) | MA40065B1 (lt) |
PL (2) | PL3148588T3 (lt) |
PT (2) | PT3903774T (lt) |
RS (2) | RS63859B1 (lt) |
SI (2) | SI3903774T1 (lt) |
WO (1) | WO2015181567A1 (lt) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB202005057D0 (en) | 2020-04-06 | 2020-05-20 | Emeramed Ltd | New Use |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6586600B2 (en) | 2000-12-06 | 2003-07-01 | University Of Kentucky Research Foundation | Multidentate sulfur-containing ligands |
US8349359B2 (en) * | 2004-11-07 | 2013-01-08 | Your Energy Systems, LLC | Liposomal formulation for oral administration of glutathione (reduced) |
US8950583B2 (en) | 2008-12-06 | 2015-02-10 | Ermes Medical Company Limited | Method to remove heavy metals from a mammal |
US8575218B2 (en) | 2009-09-28 | 2013-11-05 | The University Of Kentucky Research Foundation | Thiol-containing compounds for the removal of elements from tissues and formulations therefor |
IN2012DN02586A (lt) | 2009-09-28 | 2015-08-28 | Univ Kentucky Res Found | |
US8426368B2 (en) | 2010-03-25 | 2013-04-23 | The University Of Kentucky Research Foundation | Method of ameliorating oxidative stress and supplementing the diet |
US20110237776A1 (en) | 2010-03-25 | 2011-09-29 | Haley Boyd E | Aromatic compounds with sulfur containing ligands |
-
2014
- 2014-05-30 GB GB1409662.2A patent/GB2526623A/en not_active Withdrawn
-
2015
- 2015-05-29 HU HUE21180847A patent/HUE060927T2/hu unknown
- 2015-05-29 LT LTEP21180847.2T patent/LT3903774T/lt unknown
- 2015-05-29 ES ES21180847T patent/ES2938080T3/es active Active
- 2015-05-29 WO PCT/GB2015/051572 patent/WO2015181567A1/en active Application Filing
- 2015-05-29 DK DK15733860.9T patent/DK3148588T3/da active
- 2015-05-29 PT PT211808472T patent/PT3903774T/pt unknown
- 2015-05-29 SI SI201531911T patent/SI3903774T1/sl unknown
- 2015-05-29 PL PL15733860T patent/PL3148588T3/pl unknown
- 2015-05-29 MA MA40065A patent/MA40065B1/fr unknown
- 2015-05-29 PL PL21180847.2T patent/PL3903774T3/pl unknown
- 2015-05-29 HU HUE15733860A patent/HUE055575T2/hu unknown
- 2015-05-29 US US15/313,877 patent/US20170202791A1/en not_active Abandoned
- 2015-05-29 HR HRP20230105TT patent/HRP20230105T1/hr unknown
- 2015-05-29 LT LTEPPCT/GB2015/051572T patent/LT3148588T/lt unknown
- 2015-05-29 FI FIEP21180847.2T patent/FI3903774T3/fi active
- 2015-05-29 RS RS20221189A patent/RS63859B1/sr unknown
- 2015-05-29 SI SI201531710T patent/SI3148588T1/sl unknown
- 2015-05-29 EP EP15733860.9A patent/EP3148588B1/en active Active
- 2015-05-29 EP EP21180847.2A patent/EP3903774B1/en active Active
- 2015-05-29 PT PT157338609T patent/PT3148588T/pt unknown
- 2015-05-29 ES ES15733860T patent/ES2882977T3/es active Active
- 2015-05-29 DK DK21180847.2T patent/DK3903774T3/da active
- 2015-05-29 RS RS20210852A patent/RS62095B1/sr unknown
-
2017
- 2017-11-22 US US15/821,371 patent/US20180250247A1/en not_active Abandoned
-
2020
- 2020-02-06 MA MA54630A patent/MA54630B1/fr unknown
-
2021
- 2021-08-13 HR HRP20211309TT patent/HRP20211309T1/hr unknown
- 2021-09-07 CY CY20211100788T patent/CY1124509T1/el unknown
- 2021-12-22 US US17/558,975 patent/US12128017B2/en active Active
-
2022
- 2022-09-27 US US17/953,622 patent/US11628151B2/en active Active
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