LV12314A - Holecistokinina antagnoisti - Google Patents
Holecistokinina antagnoistiInfo
- Publication number
- LV12314A LV12314A LV990072A LV990072A LV12314A LV 12314 A LV12314 A LV 12314A LV 990072 A LV990072 A LV 990072A LV 990072 A LV990072 A LV 990072A LV 12314 A LV12314 A LV 12314A
- Authority
- LV
- Latvia
- Prior art keywords
- holecistokinina
- antagnoist
- cholecystokinin
- compounds
- relates
- Prior art date
Links
- 229940107137 cholecystokinin Drugs 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- IZTQOLKUZKXIRV-YRVFCXMDSA-N sincalide Chemical compound C([C@@H](C(=O)N[C@@H](CCSC)C(=O)NCC(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(N)=O)NC(=O)[C@@H](N)CC(O)=O)C1=CC=C(OS(O)(=O)=O)C=C1 IZTQOLKUZKXIRV-YRVFCXMDSA-N 0.000 abstract 2
- 102100025841 Cholecystokinin Human genes 0.000 abstract 1
- 101800001982 Cholecystokinin Proteins 0.000 abstract 1
- 108010089448 Cholecystokinin B Receptor Proteins 0.000 abstract 1
- 102000004859 Cholecystokinin Receptors Human genes 0.000 abstract 1
- 108090001085 Cholecystokinin Receptors Proteins 0.000 abstract 1
- 102100021022 Gastrin Human genes 0.000 abstract 1
- 102000052874 Gastrin receptors Human genes 0.000 abstract 1
- 108010052343 Gastrins Proteins 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 125000003310 benzodiazepinyl group Chemical class N1N=C(C=CC2=C1C=CC=C2)* 0.000 abstract 1
- AOXOCDRNSPFDPE-UKEONUMOSA-N chembl413654 Chemical compound C([C@H](C(=O)NCC(=O)N[C@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@H](CCSC)C(=O)N[C@H](CC(O)=O)C(=O)N[C@H](CC=1C=CC=CC=1)C(N)=O)NC(=O)[C@@H](C)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H]1N(CCC1)C(=O)CNC(=O)[C@@H](N)CCC(O)=O)C1=CC=C(O)C=C1 AOXOCDRNSPFDPE-UKEONUMOSA-N 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/04—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/14—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
- C07D243/16—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
- C07D243/18—1,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
- C07D243/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D419/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms
- C07D419/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D419/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Ophthalmology & Optometry (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Biochemistry (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Joining Of Building Structures In Genera (AREA)
- Materials For Medical Uses (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Prostheses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68300791A | 1991-04-10 | 1991-04-10 | |
| US76427791A | 1991-09-23 | 1991-09-23 | |
| US07/848,790 US5220018A (en) | 1991-04-10 | 1992-03-10 | Cholecystokinin antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| LV12314A true LV12314A (lv) | 1999-07-20 |
| LV12314B LV12314B (lv) | 1999-11-20 |
Family
ID=27418411
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LVP-99-72A LV12314B (lv) | 1991-04-10 | 1999-04-27 | Holecistokinīna antagonisti |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0508796B1 (lv) |
| JP (1) | JP3012086B2 (lv) |
| KR (1) | KR920019762A (lv) |
| AT (1) | ATE168103T1 (lv) |
| AU (1) | AU662322B2 (lv) |
| CA (1) | CA2066083C (lv) |
| CY (1) | CY2102B1 (lv) |
| DE (1) | DE69226119T2 (lv) |
| DK (1) | DK0508796T3 (lv) |
| ES (1) | ES2117654T3 (lv) |
| FI (1) | FI112220B (lv) |
| GR (1) | GR3027672T3 (lv) |
| HK (1) | HK1011016A1 (lv) |
| IE (1) | IE921138A1 (lv) |
| IL (1) | IL101514A (lv) |
| LV (1) | LV12314B (lv) |
| NO (1) | NO300971B1 (lv) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2682381B1 (fr) * | 1991-10-10 | 1995-04-07 | Rhone Poulenc Rorer Sa | Derives de benzodiazepine, leur preparation et les medicaments les contenant. |
| WO1993008175A1 (en) * | 1991-10-24 | 1993-04-29 | Glaxo Group Limited | Benzodiazepine derivatives as antagonists of gastrin and/or cholecystokinin |
| US5597915A (en) * | 1992-03-16 | 1997-01-28 | Merck Sharp & Dohme Ltd. | Benzodiazepine derivatives, compositions containing them and their use in therapy |
| AU670431B2 (en) * | 1992-03-24 | 1996-07-18 | Merck Sharp & Dohme Limited | 3-ureido substituted benzodiazepin-2-ones having cholecystokinin and/or gastrin antagonistic activity and their use in therapy |
| US5378838A (en) * | 1993-01-13 | 1995-01-03 | Merck & Co., Inc. | Benzodiazepine cholecystokinin antagonists |
| GB9308431D0 (en) * | 1993-04-23 | 1993-06-09 | Glaxo Spa | Chemical compounds |
| GB9514031D0 (en) * | 1995-07-10 | 1995-09-06 | Zeneca Ltd | Chemical process |
| US6107330A (en) * | 1995-08-07 | 2000-08-22 | Daiichi Pharmaceutical Co., Ltd. | Inhibitor for narcotic analgesic dependence/resistance acquisition |
| US5952506A (en) * | 1997-04-24 | 1999-09-14 | American Home Products Corporation | Process for the synthesis of 4- 6- (hexylcarbamoyloxy) hexylcarbamoyloxy!-piperidine-1-carboxylic acid 4-phenoxyphenyl ester |
| FR2782997A1 (fr) * | 1998-09-08 | 2000-03-10 | Hoechst Marion Roussel Inc | Nouveaux derives de la benzodiazepinone, procede de preparation et intermediaires de ce procede, application a titre de medicaments et compositions pharmaceutiques les renfermant |
| WO2004101533A1 (en) * | 2003-05-12 | 2004-11-25 | Janssen Pharmaceutica, N.V. | 1, 3, 4-benzotriazepin-2-one salts and their use as cck receptor ligands |
| CN101061116A (zh) * | 2004-09-24 | 2007-10-24 | 詹森药业有限公司 | 磺酰胺化合物 |
| EP2533775A1 (en) * | 2010-02-12 | 2012-12-19 | Universita' Degli Studi di Firenze | Carbonic anhydrase inhibitors |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4820834A (en) * | 1984-06-26 | 1989-04-11 | Merck & Co., Inc. | Benzodiazepine analogs |
| CA1332410C (en) * | 1984-06-26 | 1994-10-11 | Roger M. Freidinger | Benzodiazepine analogs |
| IL96613A0 (en) * | 1989-12-18 | 1991-09-16 | Merck & Co Inc | Pharmaceutical compositions containing benzodiazepine analogs |
| CA2032226A1 (en) * | 1989-12-18 | 1991-06-19 | Mark G. Bock | Benzodiazepine analogs |
-
1992
- 1992-04-07 IL IL10151492A patent/IL101514A/en not_active IP Right Cessation
- 1992-04-08 CA CA002066083A patent/CA2066083C/en not_active Expired - Fee Related
- 1992-04-09 EP EP92303191A patent/EP0508796B1/en not_active Expired - Lifetime
- 1992-04-09 AU AU14798/92A patent/AU662322B2/en not_active Ceased
- 1992-04-09 FI FI921576A patent/FI112220B/fi not_active IP Right Cessation
- 1992-04-09 DE DE69226119T patent/DE69226119T2/de not_active Expired - Fee Related
- 1992-04-09 ES ES92303191T patent/ES2117654T3/es not_active Expired - Lifetime
- 1992-04-09 NO NO921409A patent/NO300971B1/no not_active IP Right Cessation
- 1992-04-09 AT AT92303191T patent/ATE168103T1/de not_active IP Right Cessation
- 1992-04-09 IE IE113892A patent/IE921138A1/en not_active IP Right Cessation
- 1992-04-09 KR KR1019920005882A patent/KR920019762A/ko not_active Application Discontinuation
- 1992-04-09 DK DK92303191T patent/DK0508796T3/da active
- 1992-04-10 JP JP04135544A patent/JP3012086B2/ja not_active Expired - Fee Related
-
1998
- 1998-08-19 GR GR980401851T patent/GR3027672T3/el unknown
- 1998-10-27 CY CY9800045A patent/CY2102B1/xx unknown
- 1998-11-10 HK HK98111885A patent/HK1011016A1/xx not_active IP Right Cessation
-
1999
- 1999-04-27 LV LVP-99-72A patent/LV12314B/lv unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ATE168103T1 (de) | 1998-07-15 |
| DE69226119T2 (de) | 1999-02-11 |
| LV12314B (lv) | 1999-11-20 |
| JP3012086B2 (ja) | 2000-02-21 |
| AU1479892A (en) | 1992-11-19 |
| IL101514A0 (en) | 1992-12-30 |
| JPH0687838A (ja) | 1994-03-29 |
| CA2066083A1 (en) | 1992-10-11 |
| GR3027672T3 (en) | 1998-11-30 |
| EP0508796A1 (en) | 1992-10-14 |
| EP0508796B1 (en) | 1998-07-08 |
| CY2102B1 (en) | 2002-04-05 |
| CA2066083C (en) | 2002-10-08 |
| NO921409D0 (no) | 1992-04-09 |
| AU662322B2 (en) | 1995-08-31 |
| FI112220B (fi) | 2003-11-14 |
| FI921576A0 (fi) | 1992-04-09 |
| DE69226119D1 (de) | 1998-08-13 |
| IL101514A (en) | 1996-01-31 |
| DK0508796T3 (da) | 1998-10-26 |
| IE921138A1 (en) | 1992-10-21 |
| ES2117654T3 (es) | 1998-08-16 |
| FI921576A (fi) | 1992-10-11 |
| NO300971B1 (no) | 1997-08-25 |
| HK1011016A1 (en) | 1999-07-02 |
| KR920019762A (ko) | 1992-11-19 |
| NO921409L (no) | 1992-10-12 |
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