LU503077B1 - A Small Compound Prescription Of Traditional Chinese Medicine For Treating Gastric Ulcer And Duodenal Ulcer - Google Patents

A Small Compound Prescription Of Traditional Chinese Medicine For Treating Gastric Ulcer And Duodenal Ulcer Download PDF

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Publication number
LU503077B1
LU503077B1 LU503077A LU503077A LU503077B1 LU 503077 B1 LU503077 B1 LU 503077B1 LU 503077 A LU503077 A LU 503077A LU 503077 A LU503077 A LU 503077A LU 503077 B1 LU503077 B1 LU 503077B1
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Prior art keywords
traditional chinese
ulcer
chinese medicine
compound prescription
small compound
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LU503077A
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German (de)
Inventor
Baofu Zhang
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Baofu Zhang
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Priority to LU503077A priority Critical patent/LU503077B1/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/57Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/148Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with compounds of unknown constitution, e.g. material from plants or animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4875Compounds of unknown constitution, e.g. material from plants or animals

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Botany (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a small compound prescription of traditional Chinese medicine for treating gastric ulcer and duodenal ulcer, which is made of Membrane of Chicken Gizzard, clove bud and eggshell, its preparation steps: first, sprinkling 95% alcohol on the eggshell to ignite, so that the eggshell is burned and carbonized, and then cooled; then, it is mixed with Membrane of Chicken Gizzard and clove bud, and ground into powder to make capsules. The invention adopts a small compound prescription of traditional Chinese medicine, which is composed of Membrane of Chicken Gizzard, clove bud and eggshell, and only uses three traditional Chinese medicinal materials to form the medicine, the medicine types are few, and the medicinal materials are all broad-source medicinal materials, and the cost is low; and in the small compound prescription of traditional Chinese medicine of the invention, the synergistic effect of each medicine can promote blood circulation, relieve pain and acid, protect gastric mucosa, quickly kill Helicobacter pylori, and make the ulcer surface heal quickly, and after application verification, its therapeutic effect is remarkable.

Description

BL-5588
LU503077
A Small Compound Prescription Of Traditional Chinese Medicine For
Treating Gastric Ulcer And Duodenal Ulcer
Technical Field
[0001] The invention relates to the technical field of medicines, in particular to a small compound prescription of traditional Chinese medicine for treating gastric ulcer and duodenal ulcer.
Background
[0002] Peptic ulcer mainly refers to chronic ulcers that occur in the stomach and duodenum, and can also occur in the lower part of esophagus, around the Gastrojejunal Anastomosis, and
Meckel's diverticulum containing ectopic gastric mucosa. The formation of these ulcers is related to the digestion of gastric acid and pepsin, so they are called peptic ulcers. In recent years, studies have found that the formation of ulcers is related to the presence of
Helicobacter pylori. Most of the disease (more than 95%) is located in the stomach and duodenum, so it is also called gastroduodenal ulcer. In-depth studies have shown that gastric ulcer disease and duodenal ulcer disease have obvious differences in etiology and pathogenesis, and they are not the same disease, but due to their similar epidemiology, clinical manifestations and drug treatment response, it is customary to lump them together. Duodenal ulcer is more common than gastric ulcer. It occurs more frequently in young adults, more men than women, children can also suffer from it, the proportion of elderly patients has also increased year by year.
[0003] At present, most of the medicines used to treat gastric ulcer and duodenal ulcer are western medicines, which have serious side effects, damage the liver, and are prone to recurrence.
[0004] Although the traditional Chinese medicine compound has been effective in the treatment of gastric ulcer and duodenal ulcer, its side effects are low, but its general compound has many kinds of drugs, and the treatment cost is high.
Summary of the invention
[0005] Therefore, based on the above background, the invention provides a small compound 1
BL-5588 prescription of traditional Chinese medicine for treating gastric ulcer and duodenal ulcer, 17508077 which has remarkable therapeutic effect and low cost.
[0006] The technical scheme provided by the invention is as follows:
[0007] a small compound prescription of traditional Chinese medicine for treating gastric ulcer and duodenal ulcer, it is made of Membrane of Chicken Gizzard, clove bud and eggshell.
[0008] Further, the raw materials are as follows in parts by weight:
[0009] 2-15 parts of Membrane of Chicken Gizzard, 2-15 parts of clove buds, 8-25 parts of eggshells.
[0010] Further, the raw materials are as follows in parts by weight:
[0011] 4 parts of Membrane of Chicken Gizzard, 4 parts of clove buds, 12 parts of eggshells.
[0012] Further, Membrane of Chicken Gizzard is Membrane of Raw Chicken Gizzard.
[0013] Further, it is an oral preparation.
[0014] Further, the preparation steps are as follows:
[0015] first, sprinkling 95% alcohol on the eggshell to ignite, so that the eggshell is burned and carbonized, and then cooled; then, it is mixed with Membrane of Chicken Gizzard and clove bud, and ground into powder to make capsules, each capsule 1s filled with 2g of drug.
[0016] Medication pharmacology of the invention 1s as follows:
[0017] Membrane of Chicken Gizzard is neutral in nature, the medicinal effect acts on the spleen, stomach, small intestine and bladder, strengthens the stomach and digestion, arrests seminal emission, relieves stranguria and discharges calculus;
[0018] Clove bud is warm in nature, the medicinal effect acts on the spleen, stomach and kidney, warms the spleen and stomach and relieves flatulence, warms the kidney, promotes qi circulation to relieve pain, restores consciousness and induces resuscitation, expels toxins from the body and disperses parasites, roundworms, etc. from the body;
[0019] Eggshell: astringent, inhibiting gastric acid secretion, calcium supplement.
[0020] Compared with the prior art, the advantageous effects of the invention are as follows:
[0021] the invention adopts a small compound prescription of traditional Chinese medicine, which is composed of Membrane of Chicken Gizzard, clove bud and eggshell, and only uses three traditional Chinese medicinal materials to form the medicine, the medicine types are few, 2
BL-5588 and the medicinal materials are all broad-source medicinal materials, and the cost is low; 0503077
[0022] in the small compound prescription of traditional Chinese medicine of the invention, the synergistic effect of each medicine can promote blood circulation, relieve pain and acid, protect gastric mucosa, quickly kill Helicobacter pylori, and make the ulcer surface heal quickly, and after application verification, its therapeutic effect is remarkable.
Description of Embodiments
[0023] It should be noted that the following detailed description is exemplary and intended to provide further explanation of the invention. Unless otherwise specified, all technical and scientific terms used herein have the same meaning as commonly understood by the person of ordinary skill in the art to which this invention belongs.
[0024] It should be noted that the terms used herein are for the object of describing specific embodiments only, and is not intended to limit the exemplary embodiments of invention. As used herein, the singular forms are also intended to include the plural forms unless the context clearly dictates otherwise, in addition, it should also be understood that when the terms “comprising” and/or “including” are used in this specification, they indicate the presence of features, steps, operations, and/or combinations thereof.
[0025] Embodiment 1: a small compound prescription of traditional Chinese medicine for treating gastric ulcer and duodenal ulcer, it is made of 4 parts of Membrane of Chicken
Gizzard, 4 parts of clove buds, 12 parts of eggshells.
[0026] The preparation steps are as follows:
[0027] first, sprinkling 95% alcohol on the eggshell to ignite, so that the eggshell is burned and carbonized, and then cooled; then, it is mixed with Membrane of Chicken Gizzard and clove bud, and ground into powder to make capsules, each capsule is filled with 2g of drug.
[0028] Comparative Example 1: a small compound prescription of traditional Chinese medicine for treating gastric ulcer and duodenal ulcer, it is made of 4 parts of Membrane of
Chicken Gizzard, 4 parts of clove buds, 12 parts of eggshells.
[0029] The preparation steps are as follows:
[0030] mixing Membrane of Chicken Gizzard, clove bud and eggshell, and grounding them into powder to make capsules, each capsule is filled with 2g of drug. 3
BL-5588
[0031] Embodiment 2: recruiting 39 volunteers diagnosed with gastric ulcer and duodenal 10503077 ulcer, aged between 25 and 51 years old, 21 males and 18 females, wherein 12 volunteers only suffered from gastric ulcer, 18 volunteers only suffered from duodenal ulcer, 9 volunteers suffered from both gastric ulcer and duodenal ulcer. These patients were randomly divided into three groups, 13 in each group, namely the experimental group, the comparative experimental group 1, and the comparative experimental group 2, wherein the experimental group was treated with Embodiment 1, three times a day, one capsule at a time; the comparison experimental group 1 was treated with Comparative Example 1, three times a day, one capsule at a time, and the comparative experimental group 2 was given 40 mg omeprazole, once a day, after continuous treatment for one month, the therapeutic effects are shown in
Table 1.
[0032] During the treatment, patients should avoid alcohol, spicy, cold, acid and gastrointestinal irritating foods, such as shrimp, crab, fish, etc.
[0033] Therapeutic effect criteria:
[0034] Cure: signs and symptoms are completely improved, diet and digestion are normal, and spirit is refreshed;
[0035] Significantly effective: signs and symptoms are completely improved, diet and digestion are basically normal, and the spirit is refreshed;
[0036] Effective: there are changes in signs and symptoms, occasional discomfort, but it is acceptable;
[0037] Ineffective: no change in signs, symptoms are as before.
[0038] Table 1: The Results Of Therapeutic Effects effective rate (%
I | 1 I I I experimental group 1 commen | 1 | OV TT UT experimental group 2
[0039] Embodiment 3: Typical Cases
[0040] Case 1: Mr. Li, male, farmer, 56 years old, complained of frequent gastric distension and pain, which became more severe within two hours after meals. He underwent gastroscopy 4
BL-5588 in Gongyi City People's Hospital and the result showed gastric ulcer, he was treated with 17508077
Embodiment 1, his pain was relieved soon after taking the medicine, after taking it continuously for 10 days, his discomfort disappeared, and then he was retested by gastroscope, the ulcer surface disappeared and he recovered.
[0041] Case 2: Mr. Zhang, male, worker, 38 years old, complained of stomach pain with stomach acid for more than a month, according to the characteristics of “hunger pain”, he was treated with Embodiment 1 for 20 consecutive days, after taking the medicine, his pain gradually eased, after the medication ended, his pain disappeared, after the treatment, he controls his diet and lives regularly, and there is no recurrence.
[0042] Case 3: Ms. Liu, female, 42 years old, complained of frequent abdominal distension, obvious stomach pain after meals and during fasting, gastroscope showed duodenal ulcer, she was treated with Embodiment 1 continuously for 1 month, her abdominal distension and abdominal pain symptoms disappeared, and then continued medication for 10 days to consolidate the curative effect.
[0043] The above-mentioned embodiments are preferred embodiments of the invention, but the embodiments of the invention are not limited by the above-mentioned embodiments, and any other changes, modifications, substitutions, combinations and the simplification that do not deviate from the spirit and principle of the invention should be equivalent substitutions, which are all included in the protection scope of the invention.

Claims (5)

BL-5588 Claims LU503077
1. A small compound prescription of traditional Chinese medicine for treating gastric ulcer and duodenal ulcer, wherein it is made of Membrane of Chicken Gizzard, clove bud and eggshell.
2. A small compound prescription of traditional Chinese medicine for treating gastric ulcer and duodenal ulcer according to claim 1, wherein the raw materials are as follows in parts by weight: 2-15 parts of Membrane of Chicken Gizzard, 2-15 parts of clove buds, 8-25 parts of eggshells.
3. A small compound prescription of traditional Chinese medicine for treating gastric ulcer and duodenal ulcer according to claim 1, wherein the raw materials are as follows in parts by weight: 4 parts of Membrane of Chicken Gizzard, 4 parts of clove buds, 12 parts of eggshells.
4. A small compound prescription of traditional Chinese medicine for treating gastric ulcer and duodenal ulcer according to any one of claims 1 to 3, wherein it is an oral preparation.
5. A small compound prescription of traditional Chinese medicine for treating gastric ulcer and duodenal ulcer according to claim 4, wherein the preparation steps are as follows: first, sprinkling 95% alcohol on the eggshell to ignite, so that the eggshell is burned and carbonized, and then cooled; then, it is mixed with Membrane of Chicken Gizzard and clove bud, and ground into powder to make capsules. 6
LU503077A 2022-11-17 2022-11-17 A Small Compound Prescription Of Traditional Chinese Medicine For Treating Gastric Ulcer And Duodenal Ulcer LU503077B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
LU503077A LU503077B1 (en) 2022-11-17 2022-11-17 A Small Compound Prescription Of Traditional Chinese Medicine For Treating Gastric Ulcer And Duodenal Ulcer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU503077A LU503077B1 (en) 2022-11-17 2022-11-17 A Small Compound Prescription Of Traditional Chinese Medicine For Treating Gastric Ulcer And Duodenal Ulcer

Publications (1)

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LU503077B1 true LU503077B1 (en) 2023-05-23

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LU503077A LU503077B1 (en) 2022-11-17 2022-11-17 A Small Compound Prescription Of Traditional Chinese Medicine For Treating Gastric Ulcer And Duodenal Ulcer

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