LU500350B1 - Fluorescent probe for detecting methylglyoxal and preparation and use thereof - Google Patents

Fluorescent probe for detecting methylglyoxal and preparation and use thereof Download PDF

Info

Publication number
LU500350B1
LU500350B1 LU500350A LU500350A LU500350B1 LU 500350 B1 LU500350 B1 LU 500350B1 LU 500350 A LU500350 A LU 500350A LU 500350 A LU500350 A LU 500350A LU 500350 B1 LU500350 B1 LU 500350B1
Authority
LU
Luxembourg
Prior art keywords
reaction
soluble salt
formula
methylglyoxal
preparation
Prior art date
Application number
LU500350A
Other languages
German (de)
English (en)
Inventor
Zhiming Wang
Xianshun Zeng
Tianhui Wang
Mingzhe Li
Lingling Pu
Xinxing Wang
Chang Liu
Zhaoli Chen
Longfei Xu
Original Assignee
Inst Of Environmental And Operational Medicine Academy Of Military Medical Science Academy Of Milita
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Of Environmental And Operational Medicine Academy Of Military Medical Science Academy Of Milita filed Critical Inst Of Environmental And Operational Medicine Academy Of Military Medical Science Academy Of Milita
Application granted granted Critical
Publication of LU500350B1 publication Critical patent/LU500350B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
    • C09B23/14—Styryl dyes
    • C09B23/145—Styryl dyes the ethylene chain carrying an heterocyclic residue, e.g. heterocycle-CH=CH-C6H5
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K11/00—Luminescent, e.g. electroluminescent, chemiluminescent materials
    • C09K11/06—Luminescent, e.g. electroluminescent, chemiluminescent materials containing organic luminescent materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6456—Spatial resolved fluorescence measurements; Imaging
    • G01N21/6458—Fluorescence microscopy
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K2211/00—Chemical nature of organic luminescent or tenebrescent compounds
    • C09K2211/10—Non-macromolecular compounds
    • C09K2211/1003—Carbocyclic compounds
    • C09K2211/1007—Non-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K2211/00—Chemical nature of organic luminescent or tenebrescent compounds
    • C09K2211/10—Non-macromolecular compounds
    • C09K2211/1018—Heterocyclic compounds
    • C09K2211/1025—Heterocyclic compounds characterised by ligands
    • C09K2211/1029—Heterocyclic compounds characterised by ligands containing one nitrogen atom as the heteroatom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • General Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Optics & Photonics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
LU500350A 2021-06-15 2021-06-29 Fluorescent probe for detecting methylglyoxal and preparation and use thereof LU500350B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202110661608.9A CN113387865B (zh) 2021-06-15 2021-06-15 一种用于检测丙酮醛的荧光探针及其制备方法和应用

Publications (1)

Publication Number Publication Date
LU500350B1 true LU500350B1 (en) 2022-02-03

Family

ID=77621524

Family Applications (1)

Application Number Title Priority Date Filing Date
LU500350A LU500350B1 (en) 2021-06-15 2021-06-29 Fluorescent probe for detecting methylglyoxal and preparation and use thereof

Country Status (2)

Country Link
CN (1) CN113387865B (zh)
LU (1) LU500350B1 (zh)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109369569B (zh) * 2018-11-01 2022-09-30 华东师范大学 一类检测丙酮醛的荧光探针及其制备方法和应用
CN111196821B (zh) * 2018-11-16 2022-11-29 中国科学院上海药物研究所 一类化合物、其制备方法及其作为检测丙酮醛近红外二区荧光探针的应用
CN110357817B (zh) * 2019-08-02 2022-07-26 华东理工大学 一类可逆性检测丙酮醛和乙二醛荧光探针及其制备方法和应用

Also Published As

Publication number Publication date
CN113387865B (zh) 2022-06-07
CN113387865A (zh) 2021-09-14

Similar Documents

Publication Publication Date Title
EP2099807B1 (en) Oxidation resistant indicator molecules
EP1557422B1 (en) Detection of analytes in aqueous environments
US9051598B2 (en) Specific detection of D-glucose by a tetraphenylethene-base fluorescent sensor
CN106833625B (zh) 一种双光子溶酶体pH荧光探针及其制备方法和应用
Yang et al. A highly sensitive fluorescent probe for the detection of bisulfite ion and its application in living cells
CN111518071B (zh) 一种半胱氨酸近红外荧光探针的制备和应用
Zhong et al. A novel near-infrared fluorescent probe for highly selective recognition of hydrogen sulfide and imaging in living cells
Yang et al. BODIPY-based fluorescent probe for cysteine detection and its applications in food analysis, test strips and biological imaging
Chen et al. A nitroso-based fluorogenic probe for rapid detection of hydrogen sulfide in living cells
Jin et al. Novel near-infrared pH-sensitive cyanine-based fluorescent probes for intracellular pH monitoring
US6756231B1 (en) Diaminorhodamine derivative
Cao et al. A “turn-on” fluorescent probe for the detection of Cu 2+ in living cells based on a signaling mechanism of N [double bond, length as m-dash] N isomerization
CN111848633B (zh) 一类香豆素-Tröger’s base类Fe3+荧光探针及其制备方法
CN107286151B (zh) 一种基于咔唑的双光子荧光探针及其制备方法和用途
CN113121580B (zh) 一种过氧化氢荧光探针及其制备方法和应用
LU500350B1 (en) Fluorescent probe for detecting methylglyoxal and preparation and use thereof
CN110257055A (zh) 高选择性检测谷胱甘肽比率型荧光探针及合成方法与应用
CN110407835A (zh) 咪唑并[1,2-a]吡啶近红外比率型pH荧光探针及其制备和应用
CN114106024B (zh) 一种荧光探针及其制备方法和应用
CN104927836A (zh) 一种对环境极性敏感的近红外荧光探针及其合成方法和应用
CN110483573B (zh) 一种线粒体靶向次氯酸比率型双光子荧光探针及其制备方法和用途
Yang et al. Dual-lifetime luminescent probe for time-resolved ratiometric oxygen sensing and imaging
CN115197204B (zh) 基于噻吩-氧杂蒽染料的硫化氢荧光探针的制备和应用
CN110669350A (zh) 一种哌啶基bodipy类红光荧光染料及其制备方法和应用
CN109988561A (zh) 咪唑并[1,2-a]吡啶类比率型pH荧光探针及其制备方法和应用

Legal Events

Date Code Title Description
FG Patent granted

Effective date: 20220203