LTIP1718A - New heterocyclic compounds as antagonists of exitatory amino acids receptors, process for their preparation and their use - Google Patents

New heterocyclic compounds as antagonists of exitatory amino acids receptors, process for their preparation and their use

Info

Publication number
LTIP1718A
LTIP1718A LTIP1718A LTIP1718A LTIP1718A LT IP1718 A LTIP1718 A LT IP1718A LT IP1718 A LTIP1718 A LT IP1718A LT IP1718 A LTIP1718 A LT IP1718A LT IP1718 A LTIP1718 A LT IP1718A
Authority
LT
Lithuania
Prior art keywords
antagonists
preparation
amino acids
heterocyclic compounds
new heterocyclic
Prior art date
Application number
LTIP1718A
Other languages
English (en)
Inventor
Britt-Marie Eva Swahn
Alf Erling Albert Claesson
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of LTIP1718A publication Critical patent/LTIP1718A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509Six-membered rings
    • C07F9/650952Six-membered rings having the nitrogen atoms in the positions 1 and 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576Six-membered rings
    • C07F9/59Hydrogenated pyridine rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
LTIP1718A 1990-11-15 1993-12-30 New heterocyclic compounds as antagonists of exitatory amino acids receptors, process for their preparation and their use LTIP1718A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9003652A SE9003652D0 (sv) 1990-11-15 1990-11-15 New heterocyclic compounds

Publications (1)

Publication Number Publication Date
LTIP1718A true LTIP1718A (en) 1995-07-25

Family

ID=20380925

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP1718A LTIP1718A (en) 1990-11-15 1993-12-30 New heterocyclic compounds as antagonists of exitatory amino acids receptors, process for their preparation and their use

Country Status (17)

Country Link
EP (1) EP0557375A1 (sv)
JP (1) JPH06502421A (sv)
CN (1) CN1061595A (sv)
AU (1) AU652399B2 (sv)
CA (1) CA2095224A1 (sv)
CZ (1) CZ80993A3 (sv)
FI (1) FI932206A0 (sv)
HU (1) HU9301417D0 (sv)
IE (1) IE913922A1 (sv)
IS (1) IS3782A7 (sv)
LT (1) LTIP1718A (sv)
MX (1) MX9101979A (sv)
NO (1) NO931679D0 (sv)
PT (1) PT99515A (sv)
SE (1) SE9003652D0 (sv)
SK (1) SK46993A3 (sv)
WO (1) WO1992008724A1 (sv)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5194430A (en) * 1990-05-17 1993-03-16 Merrell Dow Pharmaceuticals Inc. Heterocyclic-nmda antagonists
TW281670B (sv) * 1993-09-02 1996-07-21 Hoffmann La Roche
US5491241A (en) * 1993-10-18 1996-02-13 Eli Lilly And Company Bicyclic intermediates for excitatory amino acid receptor antagonists
LT3411358T (lt) 2016-02-04 2022-04-25 Takeda Pharmaceutical Company Limited Pakeistas piperidino junginys ir jo naudojimas

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1248531A (en) * 1984-04-17 1989-01-10 Jeffrey C. Watkins 4-substituted piperazine-2-carboxylic acids
JPS612519A (ja) * 1984-04-24 1986-01-08 Aron Kasei Co Ltd 射出成形法
US4906621A (en) * 1985-05-24 1990-03-06 Ciba-Geigy Corporation Certain 2-carboxypiperidyl-alkylene phosphonic acids and esters thereof useful for the treatment of disorders responsive to N-methyl-D-aspartate receptor blockade
US4740346A (en) * 1986-02-26 1988-04-26 The Budd Company Perimeter resin feeding of composite structures
JPS63112129A (ja) * 1986-10-30 1988-05-17 Toyoda Gosei Co Ltd 多色樹脂成形用金型
IL84492A0 (en) * 1986-11-21 1988-04-29 Ciba Geigy Ag Unsaturated phosphonic acids and derivatives

Also Published As

Publication number Publication date
CZ80993A3 (en) 1994-02-16
NO931679L (no) 1993-05-07
HU9301417D0 (en) 1993-09-28
AU652399B2 (en) 1994-08-25
CA2095224A1 (en) 1992-05-16
JPH06502421A (ja) 1994-03-17
FI932206A (fi) 1993-05-14
EP0557375A1 (en) 1993-09-01
SK46993A3 (en) 1993-10-06
MX9101979A (es) 1992-07-08
AU8939191A (en) 1992-06-11
SE9003652D0 (sv) 1990-11-15
IE913922A1 (en) 1992-05-20
IS3782A7 (is) 1992-05-16
FI932206A0 (fi) 1993-05-14
NO931679D0 (no) 1993-05-07
PT99515A (pt) 1992-09-30
CN1061595A (zh) 1992-06-03
WO1992008724A1 (en) 1992-05-29

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Legal Events

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