LT3684786T - Mutavęs vezikulinio stomatito viruso glikoproteinas - Google Patents
Mutavęs vezikulinio stomatito viruso glikoproteinasInfo
- Publication number
- LT3684786T LT3684786T LTEPPCT/EP2018/075824T LTEP2018075824T LT3684786T LT 3684786 T LT3684786 T LT 3684786T LT EP2018075824 T LTEP2018075824 T LT EP2018075824T LT 3684786 T LT3684786 T LT 3684786T
- Authority
- LT
- Lithuania
- Prior art keywords
- vesicular stomatitis
- stomatitis virus
- mutated glycoprotein
- glycoprotein
- mutated
- Prior art date
Links
- 102000003886 Glycoproteins Human genes 0.000 title 1
- 108090000288 Glycoproteins Proteins 0.000 title 1
- 241000711975 Vesicular stomatitis virus Species 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
- C12N2760/20222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
- C12N2760/20232—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
- C12N2760/20241—Use of virus, viral particle or viral elements as a vector
- C12N2760/20245—Special targeting system for viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
- C12N2760/20261—Methods of inactivation or attenuation
- C12N2760/20262—Methods of inactivation or attenuation by genetic engineering
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17306255 | 2017-09-22 | ||
| PCT/EP2018/075824 WO2019057974A1 (en) | 2017-09-22 | 2018-09-24 | GLYCOPROTEIN MUTATED FROM VESICULAR STOMATITIS VIRUS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT3684786T true LT3684786T (lt) | 2024-11-11 |
Family
ID=60153233
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEPPCT/EP2018/075824T LT3684786T (lt) | 2017-09-22 | 2018-09-24 | Mutavęs vezikulinio stomatito viruso glikoproteinas |
Country Status (14)
| Country | Link |
|---|---|
| US (8) | US12091434B2 (enExample) |
| EP (3) | EP4446337A3 (enExample) |
| JP (2) | JP2020534007A (enExample) |
| CA (1) | CA3076094A1 (enExample) |
| DK (1) | DK3684786T3 (enExample) |
| ES (1) | ES2991089T3 (enExample) |
| FI (1) | FI3684786T3 (enExample) |
| HR (1) | HRP20241466T1 (enExample) |
| HU (1) | HUE069207T2 (enExample) |
| LT (1) | LT3684786T (enExample) |
| PL (1) | PL3684786T3 (enExample) |
| PT (1) | PT3684786T (enExample) |
| SI (1) | SI3684786T1 (enExample) |
| WO (1) | WO2019057974A1 (enExample) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4446337A3 (en) * | 2017-09-22 | 2025-01-08 | Centre National de la Recherche Scientifique | Mutated glycoprotein of vesicular stomatitis virus |
| EP3708176A1 (en) * | 2019-03-15 | 2020-09-16 | Centre National De La Recherche Scientifique -Cnrs- | Mutant vsv ectodomain polypeptide and uses thereof |
| CA3140115A1 (en) | 2019-05-23 | 2020-11-26 | Massachusetts Institute Of Technology | Ligand discovery and gene delivery via retroviral surface display |
| EP4013459B1 (en) * | 2019-08-16 | 2025-07-23 | Mayo Foundation for Medical Education and Research | Chimeric vesiculoviruses and methods of use |
| JP2023509966A (ja) * | 2020-01-10 | 2023-03-10 | カロジェン コーポレイション | 腫瘍溶解性ウイルス様小胞の組成物および使用方法 |
| EP4100420A1 (en) * | 2020-02-06 | 2022-12-14 | Boehringer Ingelheim Vetmedica GmbH | Polypeptides useful for detecting anti-rhabdovirus antibodies |
| WO2022013872A1 (en) * | 2020-07-14 | 2022-01-20 | Ichilov Tech Ltd. | Pseudotyped viruses configured to express car in t-cells |
| EP4284821A1 (en) | 2021-01-27 | 2023-12-06 | Umoja Biopharma, Inc. | Lentivirus for generating cells expressing anti-cd19 chimeric antigen receptor |
| CN112852757A (zh) * | 2021-02-01 | 2021-05-28 | 南京大学 | 一种制备新型溶瘤病毒EM/VSV-G Ad5sPVRCD137L的方法 |
| US20240218390A1 (en) | 2021-02-26 | 2024-07-04 | Kelonia Therapeutics, Inc. | Lymphocyte targeted lentiviral vectors |
| BR112023021075A2 (pt) * | 2021-04-16 | 2023-12-12 | Massachusetts Inst Technology | Método para liberar um ou mais ácidos nucleicos a uma célula-tronco hematopoiética, e, método para edição de gene em uma célula-tronco hematopoiética |
| KR20240112950A (ko) * | 2021-12-06 | 2024-07-19 | 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 | 조작된 세포 진입에 의한 수용체-리간드 특이성의 발견을 위한 방법 및 조성물 |
| IL313473A (en) | 2021-12-15 | 2024-08-01 | Interius Biotherapeutics Inc | Pseudotyped viral particles, compositions comprising the same, and uses thereof |
| IL291148A (en) * | 2022-03-06 | 2023-10-01 | Noga Therapeutics Ltd | Lentiviral vectors for in vivo targeting of hematopoietic cells |
| AU2023272490A1 (en) | 2022-05-17 | 2024-12-12 | Umoja Biopharma, Inc. | Manufacturing viral particles |
| TW202409288A (zh) | 2022-07-25 | 2024-03-01 | 美商英特瑞斯生物療法公司 | 突變多肽、包含該等突變多肽之組合物及其用途 |
| WO2024050450A1 (en) | 2022-08-31 | 2024-03-07 | Gigamune, Inc. | Engineered enveloped vectors and methods of use thereof |
| WO2024098038A2 (en) | 2022-11-04 | 2024-05-10 | Umoja Biopharma, Inc. | Polynucleotide construct and related viral vectors and methods |
| WO2024098028A2 (en) | 2022-11-04 | 2024-05-10 | Umoja Biopharma, Inc. | Lentiviral particles displaying fusion molecules and uses thereof |
| WO2024097992A2 (en) | 2022-11-04 | 2024-05-10 | Umoja Biopharma, Inc. | Particles displaying adhesion-molecule fusions |
| KR20250160369A (ko) | 2023-01-27 | 2025-11-12 | 리제너론 파마슈티칼스 인코포레이티드 | 변형된 랩도바이러스 당단백질 및 이의 용도 |
| WO2024196738A2 (en) * | 2023-03-17 | 2024-09-26 | Kelonia Therapeutics, Inc. | In vivo daric |
| KR20250167052A (ko) * | 2023-04-10 | 2025-11-28 | 선전 제노큐리 바이오테크 컴퍼니 리미티드 | 돌연변이형 vsvg 및 표적화 벡터 |
| WO2024216227A1 (en) | 2023-04-12 | 2024-10-17 | Vyriad | Cd3-redirected vectors, components thereof, and uses of the vectors and components thereof |
| WO2024238153A1 (en) | 2023-05-15 | 2024-11-21 | Umoja Biopharma, Inc. | Lentiviral delivery of anti-cd20 chimeric antigen receptors |
| WO2025006882A1 (en) * | 2023-06-30 | 2025-01-02 | The Children's Hospital Of Philadelphia | Click chemistry assisted cell surface engineering for restoring lentivirus entry |
| WO2025017052A1 (en) * | 2023-07-18 | 2025-01-23 | Vivebiotech S.L. | Purification resin and methods for using the same |
| TW202521554A (zh) * | 2023-08-11 | 2025-06-01 | 美商克隆尼亞治療股份有限公司 | 用於修飾細胞的組成物 |
| WO2025036498A1 (zh) * | 2023-08-16 | 2025-02-20 | 深圳市济因生物科技有限公司 | 一种病毒载体及其在感染b细胞中的应用 |
| WO2025072257A1 (en) * | 2023-09-25 | 2025-04-03 | Kelonia Therapeutics, Inc. | Compositions for treating cancer |
| US12403194B2 (en) | 2023-09-25 | 2025-09-02 | Kelonia Therapeutics, Inc. | Compositions for treating cancer |
| US20250101122A1 (en) | 2023-09-25 | 2025-03-27 | Kelonia Therapeutics, Inc. | Antigen binding polypeptides |
| WO2025072615A1 (en) | 2023-09-29 | 2025-04-03 | Orbital Therapeutics, Inc. | Improved methods of making rna by splinted ligation and compositions thereof |
| WO2025102013A1 (en) | 2023-11-10 | 2025-05-15 | Vyriad | Rhabdovirus g proteins having one or more cysteine-rich regions and uses thereof |
| WO2025162379A1 (zh) * | 2024-02-01 | 2025-08-07 | 深圳市济因生物科技有限公司 | 一种多肽及包含所述多肽基因的病毒载体 |
| WO2025189142A1 (en) | 2024-03-08 | 2025-09-12 | Vyriad | Membraned vesicles and purification methods thereof |
| WO2025212851A2 (en) | 2024-04-03 | 2025-10-09 | Orbital Therapeutics, Inc. | mRNA COMPOSITIONS AND USES THEREOF IN VARICELLA ZOSTER VIRUS VACCINES |
| WO2025231174A1 (en) | 2024-04-30 | 2025-11-06 | Umoja Biopharma, Inc. | Manufacturing viral particles |
| WO2025231185A1 (en) | 2024-05-01 | 2025-11-06 | Legend Biotech Ireland Limited | Viral glycoprotein variants and uses thereof |
| WO2025235604A1 (en) | 2024-05-08 | 2025-11-13 | Umoja Biopharma, Inc. | Fusion protein for use as immune cell engager |
| WO2025259931A1 (en) | 2024-06-14 | 2025-12-18 | Orbital Therapeutics, Inc. | Compositions and methods for rna circularization |
| WO2025260074A1 (en) | 2024-06-14 | 2025-12-18 | Vyriad | Multiplexing functional polypeptides and recombinant rhabdoviral g glycoproteins on enveloped delivery vehicles |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1716858B9 (en) * | 1999-09-17 | 2009-08-12 | Wellstat Biologics Corporation | Oncolytic virus |
| NZ534492A (en) * | 2002-02-07 | 2009-10-30 | Novozymes Delta Ltd | Albumin-fused kunitz domain peptides |
| JP4411523B2 (ja) * | 2004-03-04 | 2010-02-10 | 株式会社日健総本社 | 抗ウイルス剤 |
| US8008268B2 (en) * | 2006-07-25 | 2011-08-30 | Merial Limited | Vaccines against vesicular stomatitis |
| AU2008285224B2 (en) * | 2007-08-03 | 2015-01-22 | Centre National De La Recherche Scientifique (Cnrs) | Lentiviral gene transfer vectors and their medicinal applications |
| EP2020444B1 (en) * | 2007-08-03 | 2017-05-31 | Institut Pasteur | Defective non-integrative lentiviral transfer vectors for vaccines |
| US9296790B2 (en) | 2008-10-03 | 2016-03-29 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods and compositions for protein delivery |
| BR112015013669A2 (pt) * | 2012-12-12 | 2017-11-14 | Childrens Hospital Of Eastern Ontario Res Institute Inc | composições e métodos para o tratamento de cânceres cerebrais |
| EP4446337A3 (en) | 2017-09-22 | 2025-01-08 | Centre National de la Recherche Scientifique | Mutated glycoprotein of vesicular stomatitis virus |
-
2018
- 2018-09-24 EP EP24192417.4A patent/EP4446337A3/en active Pending
- 2018-09-24 HR HRP20241466TT patent/HRP20241466T1/hr unknown
- 2018-09-24 DK DK18773448.8T patent/DK3684786T3/da active
- 2018-09-24 JP JP2020516534A patent/JP2020534007A/ja active Pending
- 2018-09-24 US US16/649,271 patent/US12091434B2/en active Active
- 2018-09-24 FI FIEP18773448.8T patent/FI3684786T3/fi active
- 2018-09-24 EP EP24192413.3A patent/EP4442816A3/en active Pending
- 2018-09-24 LT LTEPPCT/EP2018/075824T patent/LT3684786T/lt unknown
- 2018-09-24 CA CA3076094A patent/CA3076094A1/en active Pending
- 2018-09-24 EP EP18773448.8A patent/EP3684786B1/en active Active
- 2018-09-24 HU HUE18773448A patent/HUE069207T2/hu unknown
- 2018-09-24 PT PT187734488T patent/PT3684786T/pt unknown
- 2018-09-24 PL PL18773448.8T patent/PL3684786T3/pl unknown
- 2018-09-24 SI SI201831168T patent/SI3684786T1/sl unknown
- 2018-09-24 ES ES18773448T patent/ES2991089T3/es active Active
- 2018-09-24 WO PCT/EP2018/075824 patent/WO2019057974A1/en not_active Ceased
-
2023
- 2023-08-28 JP JP2023138247A patent/JP2023179436A/ja active Pending
- 2023-09-25 US US18/473,720 patent/US12030915B2/en active Active
-
2024
- 2024-04-08 US US18/629,097 patent/US12269848B2/en active Active
- 2024-04-08 US US18/629,579 patent/US12291551B2/en active Active
- 2024-04-08 US US18/629,504 patent/US12264180B2/en active Active
- 2024-04-08 US US18/629,466 patent/US12297237B2/en active Active
-
2025
- 2025-02-14 US US19/053,784 patent/US12410215B2/en active Active
- 2025-02-14 US US19/053,808 patent/US12410216B2/en active Active
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