LT2929880T - Terapinis agentas ligai, pagrįstas makrofagų inhibuojančio faktoriaus inhibuojančiu poveikiu - Google Patents

Terapinis agentas ligai, pagrįstas makrofagų inhibuojančio faktoriaus inhibuojančiu poveikiu

Info

Publication number
LT2929880T
LT2929880T LTEP14826811.3T LT14826811T LT2929880T LT 2929880 T LT2929880 T LT 2929880T LT 14826811 T LT14826811 T LT 14826811T LT 2929880 T LT2929880 T LT 2929880T
Authority
LT
Lithuania
Prior art keywords
therapeutic agent
disease based
macrophage migration
inhibitory effect
inhibitory
Prior art date
Application number
LTEP14826811.3T
Other languages
English (en)
Lithuanian (lt)
Inventor
Keiichi Tanaka
Kimiko Morimoto
Original Assignee
Toyama Chemical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co., Ltd. filed Critical Toyama Chemical Co., Ltd.
Publication of LT2929880T publication Critical patent/LT2929880T/lt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/24—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrane Compounds (AREA)
LTEP14826811.3T 2013-07-18 2014-07-17 Terapinis agentas ligai, pagrįstas makrofagų inhibuojančio faktoriaus inhibuojančiu poveikiu LT2929880T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2013149690 2013-07-18
PCT/JP2014/069026 WO2015008827A1 (ja) 2013-07-18 2014-07-17 マクロファージ遊走阻止因子の阻害作用に基づく疾患の治療剤

Publications (1)

Publication Number Publication Date
LT2929880T true LT2929880T (lt) 2016-11-25

Family

ID=52346269

Family Applications (2)

Application Number Title Priority Date Filing Date
LTEP14826811.3T LT2929880T (lt) 2013-07-18 2014-07-17 Terapinis agentas ligai, pagrįstas makrofagų inhibuojančio faktoriaus inhibuojančiu poveikiu
LTEP16169414.6T LT3078372T (lt) 2013-07-18 2014-07-17 Terapinis agentas ligai, makrofagų migraciją inhibuojančio faktoriaus inhibicinio poveikio pagrindu

Family Applications After (1)

Application Number Title Priority Date Filing Date
LTEP16169414.6T LT3078372T (lt) 2013-07-18 2014-07-17 Terapinis agentas ligai, makrofagų migraciją inhibuojančio faktoriaus inhibicinio poveikio pagrindu

Country Status (22)

Country Link
US (3) US20150353519A1 (enExample)
EP (2) EP3078372B1 (enExample)
JP (2) JP5802868B2 (enExample)
CN (1) CN105407887B (enExample)
AU (1) AU2014291149B2 (enExample)
CA (1) CA2918325C (enExample)
CY (2) CY1118140T1 (enExample)
DK (2) DK3078372T3 (enExample)
ES (2) ES2642440T3 (enExample)
HR (2) HRP20161317T1 (enExample)
HU (2) HUE034661T2 (enExample)
IL (1) IL243550B (enExample)
LT (2) LT2929880T (enExample)
NO (1) NO3078372T3 (enExample)
PL (2) PL2929880T3 (enExample)
PT (2) PT2929880T (enExample)
RS (2) RS55394B1 (enExample)
RU (2) RU2750540C2 (enExample)
SI (2) SI2929880T1 (enExample)
SM (3) SMT201700080T1 (enExample)
TW (1) TWI603965B (enExample)
WO (1) WO2015008827A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018137708A1 (zh) * 2017-01-26 2018-08-02 重庆莱美药业股份有限公司 一种纳米炭-铁复合体系及其组合物、制备方法和用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0753725B2 (ja) * 1987-10-08 1995-06-07 富山化学工業株式会社 4h―1―ベンゾピラン―4―オン誘導体およびその塩、それらの製造法並びにそれらを含有する抗炎症剤
US5922755A (en) * 1993-04-09 1999-07-13 Toyama Chemical Co., Ltd. Immunomodulator, cell adhesion inhibtor, and agent for treating, and preventing autoimmune diseases
WO1997023714A1 (de) * 1995-12-21 1997-07-03 Siemens Aktiengesellschaft Luftansaugvorrichtung mit variabler saugrohrlänge für eine brennkraftmaschine
DE10044091A1 (de) * 2000-09-07 2002-04-04 Merck Patent Gmbh Chromanonderivate
GB0507696D0 (en) * 2005-04-15 2005-05-25 Novartis Ag Organic compounds
GB0507695D0 (en) 2005-04-15 2005-05-25 Novartis Ag Organic compounds
EP1940382A2 (en) * 2005-10-07 2008-07-09 Aditech Pharma AB Combination therapy with fumaric acid esters for the treatment of autoimmune and/or inflammatory disorders
BR112014002407A2 (pt) 2011-08-30 2017-02-21 Toyama Chemical Co Ltd método para melhorar a terapia contra doenças autoimunes tais como artrite reumatóide

Also Published As

Publication number Publication date
CA2918325C (en) 2018-06-26
RS55394B1 (sr) 2017-04-28
SMT201700080B (it) 2017-03-08
WO2015008827A1 (ja) 2015-01-22
SMT201700080T1 (it) 2017-03-08
EP3078372B1 (en) 2017-09-13
PL3078372T3 (pl) 2018-02-28
SI2929880T1 (sl) 2016-12-30
US9918963B2 (en) 2018-03-20
CY1118140T1 (el) 2017-06-28
AU2014291149A1 (en) 2016-02-11
EP2929880A1 (en) 2015-10-14
RU2750540C2 (ru) 2021-06-29
EP2929880A4 (en) 2015-10-14
US20160228404A1 (en) 2016-08-11
ES2642440T3 (es) 2017-11-16
AU2014291149B2 (en) 2017-05-04
DK3078372T3 (en) 2017-10-16
DK2929880T3 (da) 2017-01-02
HRP20161317T1 (hr) 2016-12-16
HUE029800T2 (en) 2017-04-28
TW201536764A (zh) 2015-10-01
JP5802868B2 (ja) 2015-11-04
PT2929880T (pt) 2016-11-08
HUE034661T2 (en) 2018-02-28
EP2929880B1 (en) 2016-09-14
US20150353519A1 (en) 2015-12-10
EP3078372A1 (en) 2016-10-12
PT3078372T (pt) 2017-10-18
IL243550B (en) 2019-06-30
CN105407887A (zh) 2016-03-16
CA2918325A1 (en) 2015-01-22
HK1222556A1 (zh) 2017-07-07
JP6060231B2 (ja) 2017-01-11
CN105407887B (zh) 2018-09-04
SI3078372T1 (en) 2018-01-31
US20160228406A1 (en) 2016-08-11
ES2593527T3 (es) 2016-12-09
RU2641301C2 (ru) 2018-01-17
SMT201700606T1 (it) 2018-01-11
NO3078372T3 (enExample) 2018-02-10
RU2017131951A (ru) 2019-02-06
TWI603965B (zh) 2017-11-01
HRP20171497T1 (hr) 2017-11-17
IL243550A0 (en) 2016-02-29
LT3078372T (lt) 2017-11-27
RU2017131951A3 (enExample) 2020-12-18
RU2016105141A (ru) 2017-08-23
CY1119496T1 (el) 2018-03-07
JP2016034953A (ja) 2016-03-17
PL2929880T3 (pl) 2017-03-31
RS56489B1 (sr) 2018-01-31
JPWO2015008827A1 (ja) 2017-03-02

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