HRP20161317T1 - Terapijsko sredstvo za bolest koja se bazira na inhibitornom učinku čimbenika inhibitora migracije makrofaga - Google Patents
Terapijsko sredstvo za bolest koja se bazira na inhibitornom učinku čimbenika inhibitora migracije makrofaga Download PDFInfo
- Publication number
- HRP20161317T1 HRP20161317T1 HRP20161317TT HRP20161317T HRP20161317T1 HR P20161317 T1 HRP20161317 T1 HR P20161317T1 HR P20161317T T HRP20161317T T HR P20161317TT HR P20161317 T HRP20161317 T HR P20161317T HR P20161317 T1 HRP20161317 T1 HR P20161317T1
- Authority
- HR
- Croatia
- Prior art keywords
- therapeutic agent
- disease based
- macrophage migration
- inhibitory effect
- inhibitory
- Prior art date
Links
- 239000003814 drug Substances 0.000 title claims 2
- 229940124597 therapeutic agent Drugs 0.000 title claims 2
- 102000009073 Macrophage Migration-Inhibitory Factors Human genes 0.000 title 1
- 108010048043 Macrophage Migration-Inhibitory Factors Proteins 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- ANMATWQYLIFGOK-UHFFFAOYSA-N Iguratimod Chemical compound CS(=O)(=O)NC1=CC=2OC=C(NC=O)C(=O)C=2C=C1OC1=CC=CC=C1 ANMATWQYLIFGOK-UHFFFAOYSA-N 0.000 claims 1
- 208000007400 Relapsing-Remitting Multiple Sclerosis Diseases 0.000 claims 1
- 208000007118 chronic progressive multiple sclerosis Diseases 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 201000008628 secondary progressive multiple sclerosis Diseases 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/24—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Claims (1)
1. Terapijsko sredstvo za uporabu u liječenju povratno-odložene ili sekundarno progresivne multipla skleroze, u vrijeme povraćaja, naznačeno time, da sadrži N-[7-[(metilsulfonil)amino]-4-okso-6-fenoksi-4H-1-benzopiran-3-il] formamid ili sol istog.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013149690 | 2013-07-18 | ||
| PCT/JP2014/069026 WO2015008827A1 (ja) | 2013-07-18 | 2014-07-17 | マクロファージ遊走阻止因子の阻害作用に基づく疾患の治療剤 |
| EP14826811.3A EP2929880B1 (en) | 2013-07-18 | 2014-07-17 | Therapeutic agent for disease based on inhibitory effect of macrophage migration inhibitory factor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20161317T1 true HRP20161317T1 (hr) | 2016-12-16 |
Family
ID=52346269
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20161317TT HRP20161317T1 (hr) | 2013-07-18 | 2016-10-11 | Terapijsko sredstvo za bolest koja se bazira na inhibitornom učinku čimbenika inhibitora migracije makrofaga |
| HRP20171497TT HRP20171497T1 (hr) | 2013-07-18 | 2017-10-05 | Terapeutsko sredstvo za bolesti uzrokovane inhibitornim učinkom faktora inhibicije migracije makrofaga |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20171497TT HRP20171497T1 (hr) | 2013-07-18 | 2017-10-05 | Terapeutsko sredstvo za bolesti uzrokovane inhibitornim učinkom faktora inhibicije migracije makrofaga |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US20150353519A1 (hr) |
| EP (2) | EP3078372B1 (hr) |
| JP (2) | JP5802868B2 (hr) |
| CN (1) | CN105407887B (hr) |
| AU (1) | AU2014291149B2 (hr) |
| CA (1) | CA2918325C (hr) |
| CY (2) | CY1118140T1 (hr) |
| DK (2) | DK2929880T3 (hr) |
| ES (2) | ES2642440T3 (hr) |
| HK (1) | HK1222556A1 (hr) |
| HR (2) | HRP20161317T1 (hr) |
| HU (2) | HUE034661T2 (hr) |
| IL (1) | IL243550B (hr) |
| LT (2) | LT3078372T (hr) |
| NO (1) | NO3078372T3 (hr) |
| PL (2) | PL3078372T3 (hr) |
| PT (2) | PT3078372T (hr) |
| RS (2) | RS56489B1 (hr) |
| RU (2) | RU2750540C2 (hr) |
| SI (2) | SI3078372T1 (hr) |
| SM (1) | SMT201700080B (hr) |
| TW (1) | TWI603965B (hr) |
| WO (1) | WO2015008827A1 (hr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018137708A1 (zh) * | 2017-01-26 | 2018-08-02 | 重庆莱美药业股份有限公司 | 一种纳米炭-铁复合体系及其组合物、制备方法和用途 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0753725B2 (ja) * | 1987-10-08 | 1995-06-07 | 富山化学工業株式会社 | ４ｈ―１―ベンゾピラン―４―オン誘導体およびその塩、それらの製造法並びにそれらを含有する抗炎症剤 |
| KR960701633A (ko) * | 1993-04-09 | 1996-03-28 | 가쯔히꼬 나까노 | 면역조절제, 세포 접착 억제제, 및 자기면역 질병의 치료 및 예방제(immunomo-dulator, cell adhesion inhibitor, and agent for treating and preventing autoimmune diseases) |
| DE59603512D1 (de) * | 1995-12-21 | 1999-12-02 | Siemens Ag | Luftansaugvorrichtung mit variabler saugrohrlänge für eine brennkraftmaschine |
| DE10044091A1 (de) * | 2000-09-07 | 2002-04-04 | Merck Patent Gmbh | Chromanonderivate |
| GB0507695D0 (en) | 2005-04-15 | 2005-05-25 | Novartis Ag | Organic compounds |
| GB0507696D0 (en) * | 2005-04-15 | 2005-05-25 | Novartis Ag | Organic compounds |
| WO2007042035A2 (en) * | 2005-10-07 | 2007-04-19 | Aditech Pharma Ab | Combination therapy with fumaric acid esters for the treatment of autoimmune and/or inflammatory disorders |
| CN103826624A (zh) | 2011-08-30 | 2014-05-28 | 富山化学工业株式会社 | 类风湿性关节炎等自身免疫疾病的处置的改善方法 |
-
2014
- 2014-07-17 JP JP2015527333A patent/JP5802868B2/ja active Active
- 2014-07-17 EP EP16169414.6A patent/EP3078372B1/en active Active
- 2014-07-17 ES ES16169414.6T patent/ES2642440T3/es active Active
- 2014-07-17 NO NO16169414A patent/NO3078372T3/no unknown
- 2014-07-17 EP EP14826811.3A patent/EP2929880B1/en active Active
- 2014-07-17 PL PL16169414T patent/PL3078372T3/pl unknown
- 2014-07-17 LT LTEP16169414.6T patent/LT3078372T/lt unknown
- 2014-07-17 SI SI201430469T patent/SI3078372T1/en unknown
- 2014-07-17 RS RS20171061A patent/RS56489B1/sr unknown
- 2014-07-17 PT PT161694146T patent/PT3078372T/pt unknown
- 2014-07-17 DK DK14826811.3T patent/DK2929880T3/da active
- 2014-07-17 ES ES14826811.3T patent/ES2593527T3/es active Active
- 2014-07-17 PL PL14826811T patent/PL2929880T3/pl unknown
- 2014-07-17 AU AU2014291149A patent/AU2014291149B2/en active Active
- 2014-07-17 RU RU2017131951A patent/RU2750540C2/ru active
- 2014-07-17 CN CN201480040609.XA patent/CN105407887B/zh active Active
- 2014-07-17 RS RS20161048A patent/RS55394B1/sr unknown
- 2014-07-17 SI SI201430088A patent/SI2929880T1/sl unknown
- 2014-07-17 US US14/647,931 patent/US20150353519A1/en not_active Abandoned
- 2014-07-17 CA CA2918325A patent/CA2918325C/en active Active
- 2014-07-17 LT LTEP14826811.3T patent/LT2929880T/lt unknown
- 2014-07-17 WO PCT/JP2014/069026 patent/WO2015008827A1/ja active Application Filing
- 2014-07-17 DK DK16169414.6T patent/DK3078372T3/en active
- 2014-07-17 RU RU2016105141A patent/RU2641301C2/ru active
- 2014-07-17 PT PT148268113T patent/PT2929880T/pt unknown
- 2014-07-17 HU HUE16169414A patent/HUE034661T2/en unknown
- 2014-07-17 HU HUE14826811A patent/HUE029800T2/en unknown
- 2014-07-18 TW TW103124716A patent/TWI603965B/zh active
-
2015
- 2015-08-27 JP JP2015167851A patent/JP6060231B2/ja active Active
-
2016
- 2016-01-11 IL IL243550A patent/IL243550B/en active IP Right Grant
- 2016-04-19 US US15/132,981 patent/US20160228406A1/en not_active Abandoned
- 2016-04-19 US US15/132,892 patent/US9918963B2/en active Active
- 2016-09-09 HK HK16110748.6A patent/HK1222556A1/zh unknown
- 2016-10-11 HR HRP20161317TT patent/HRP20161317T1/hr unknown
- 2016-10-25 CY CY20161101077T patent/CY1118140T1/el unknown
-
2017
- 2017-02-03 SM SM201700080T patent/SMT201700080B/it unknown
- 2017-09-26 CY CY20171101008T patent/CY1119496T1/el unknown
- 2017-10-05 HR HRP20171497TT patent/HRP20171497T1/hr unknown
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