LT2806028T - Junginiai ir būdai, skirti polimorfobranduolinių ląstelių susitelkimo ir (arba) migracijos sumažinimui - Google Patents
Junginiai ir būdai, skirti polimorfobranduolinių ląstelių susitelkimo ir (arba) migracijos sumažinimuiInfo
- Publication number
- LT2806028T LT2806028T LTEP14154643.2T LT14154643T LT2806028T LT 2806028 T LT2806028 T LT 2806028T LT 14154643 T LT14154643 T LT 14154643T LT 2806028 T LT2806028 T LT 2806028T
- Authority
- LT
- Lithuania
- Prior art keywords
- recruitment
- migration
- compounds
- reducing
- methods
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 238000013508 migration Methods 0.000 title 1
- 230000005012 migration Effects 0.000 title 1
- 230000007115 recruitment Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7125—Nucleic acids or oligonucleotides having modified internucleoside linkage, i.e. other than 3'-5' phosphodiesters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1138—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against receptors or cell surface proteins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/117—Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/17—Immunomodulatory nucleic acids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11128408P | 2008-11-04 | 2008-11-04 | |
| SE0802338 | 2008-11-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| LT2806028T true LT2806028T (lt) | 2017-12-11 |
Family
ID=42153087
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| LTEP14154643.2T LT2806028T (lt) | 2008-11-04 | 2009-10-28 | Junginiai ir būdai, skirti polimorfobranduolinių ląstelių susitelkimo ir (arba) migracijos sumažinimui |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US8877724B2 (enExample) |
| EP (2) | EP2806028B1 (enExample) |
| JP (1) | JP5749651B2 (enExample) |
| AU (1) | AU2009311748B2 (enExample) |
| CA (1) | CA2778938C (enExample) |
| DK (2) | DK2806028T3 (enExample) |
| ES (2) | ES2464731T3 (enExample) |
| HR (1) | HRP20171360T1 (enExample) |
| LT (1) | LT2806028T (enExample) |
| PL (1) | PL2806028T3 (enExample) |
| WO (1) | WO2010053430A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2560782T3 (es) * | 2008-11-04 | 2016-02-22 | Index Pharmaceuticals Ab | Compuestos y métodos para el tratamiento de enfermedades inflamatorias del SNC |
| EP2468866A1 (en) | 2010-12-21 | 2012-06-27 | Index Pharmaceuticals AB | Biologically active oligonucleotides capable of modulating the immune system |
| CA2859698C (en) | 2010-12-21 | 2021-03-02 | Index Pharmaceuticals Ab | Methods for identifying biologically active oligonucleotides capable of modulating the immune system |
| EP2468867A1 (en) | 2010-12-21 | 2012-06-27 | Index Pharmaceuticals AB | Methods for identifying biologically active oligonucleotides capable of modulating the immune system |
| WO2012084991A1 (en) | 2010-12-21 | 2012-06-28 | Index Pharmaceuticals Ab | Biologically active oligonucleotides capable of modulating the immune system ii |
| US9873878B2 (en) * | 2015-03-30 | 2018-01-23 | University Of Louisville Research Foundation, Inc. | Compositions and methods for use in treating silicosis and lung cancer |
| US20180193270A1 (en) | 2016-11-29 | 2018-07-12 | PureTech Health LLC | Exosomes for delivery of therapeutic agents |
| JP2021131228A (ja) * | 2018-04-27 | 2021-09-09 | 国立大学法人 東京大学 | 難治性喘息の予防又は治療剤をスクリーニングする方法、及び難治性喘息の予防又は治療剤 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6172208B1 (en) * | 1992-07-06 | 2001-01-09 | Genzyme Corporation | Oligonucleotides modified with conjugate groups |
| SE9602300D0 (sv) * | 1996-06-11 | 1996-06-11 | Karolinska Innovations Ab | New composition and methods |
| ES2246230T3 (es) | 1999-03-18 | 2006-02-16 | The Brigham And Women's Hospital, Inc. | Compuestos de lipoxina y su utilizacion. |
| US6489311B1 (en) * | 2000-05-02 | 2002-12-03 | Charlotte-Mecklenburg Hospital Authoirty | Method for the prevention of apoptosis |
| JP2006527741A (ja) * | 2003-06-19 | 2006-12-07 | シーティーティー キャンサー ターゲッティング テクノロジーズ オイ | 細胞遊走の阻害剤 |
| SE0400399D0 (sv) | 2004-02-20 | 2004-02-20 | Index Pharmaceuticals Ab | Methods and compositions for the treatment or prevention of secondary ischemic injury |
| WO2007030580A2 (en) * | 2005-09-09 | 2007-03-15 | Oregon Health & Science University | Neuroprotectants |
| WO2007030581A2 (en) | 2005-09-09 | 2007-03-15 | Oregon Health & Science University | Neuroprotectants |
| US8309529B2 (en) | 2007-05-04 | 2012-11-13 | Index Pharmaceuticals Ab | Tumour growth inhibitory compounds and methods of their use |
| ES2560782T3 (es) | 2008-11-04 | 2016-02-22 | Index Pharmaceuticals Ab | Compuestos y métodos para el tratamiento de enfermedades inflamatorias del SNC |
| US20110280934A1 (en) | 2008-11-04 | 2011-11-17 | Asa Karlsson | Increased Expression of Specific Antigens |
-
2009
- 2009-10-28 ES ES09825058.2T patent/ES2464731T3/es active Active
- 2009-10-28 WO PCT/SE2009/051227 patent/WO2010053430A1/en not_active Ceased
- 2009-10-28 ES ES14154643.2T patent/ES2641751T3/es active Active
- 2009-10-28 EP EP14154643.2A patent/EP2806028B1/en active Active
- 2009-10-28 DK DK14154643.2T patent/DK2806028T3/en active
- 2009-10-28 DK DK09825058.2T patent/DK2342341T3/da active
- 2009-10-28 AU AU2009311748A patent/AU2009311748B2/en not_active Ceased
- 2009-10-28 LT LTEP14154643.2T patent/LT2806028T/lt unknown
- 2009-10-28 CA CA2778938A patent/CA2778938C/en active Active
- 2009-10-28 US US13/127,217 patent/US8877724B2/en active Active
- 2009-10-28 JP JP2011535537A patent/JP5749651B2/ja not_active Expired - Fee Related
- 2009-10-28 PL PL14154643T patent/PL2806028T3/pl unknown
- 2009-10-28 EP EP09825058.2A patent/EP2342341B1/en active Active
-
2014
- 2014-10-10 US US14/512,036 patent/US10046006B2/en active Active
-
2017
- 2017-09-11 HR HRP20171360TT patent/HRP20171360T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010053430A1 (en) | 2010-05-14 |
| AU2009311748A1 (en) | 2010-05-14 |
| EP2342341A1 (en) | 2011-07-13 |
| AU2009311748B2 (en) | 2014-08-21 |
| EP2342341A4 (en) | 2013-01-09 |
| US10046006B2 (en) | 2018-08-14 |
| JP5749651B2 (ja) | 2015-07-15 |
| US20110301225A1 (en) | 2011-12-08 |
| US20150099799A1 (en) | 2015-04-09 |
| CA2778938C (en) | 2019-07-02 |
| EP2806028A2 (en) | 2014-11-26 |
| DK2342341T3 (da) | 2014-05-12 |
| US8877724B2 (en) | 2014-11-04 |
| EP2806028A3 (en) | 2015-03-11 |
| EP2342341B1 (en) | 2014-03-05 |
| HRP20171360T1 (hr) | 2017-11-03 |
| DK2806028T3 (en) | 2017-10-09 |
| ES2464731T3 (es) | 2014-06-03 |
| PL2806028T3 (pl) | 2017-11-30 |
| JP2012507307A (ja) | 2012-03-29 |
| EP2806028B1 (en) | 2017-07-12 |
| ES2641751T3 (es) | 2017-11-13 |
| CA2778938A1 (en) | 2010-05-14 |
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