KR970707438A - 멀티-커필러리 전기 영동 장치(Multi-capillary electrophoretic apparatas) - Google Patents
멀티-커필러리 전기 영동 장치(Multi-capillary electrophoretic apparatas)Info
- Publication number
- KR970707438A KR970707438A KR1019970703279A KR19970703279A KR970707438A KR 970707438 A KR970707438 A KR 970707438A KR 1019970703279 A KR1019970703279 A KR 1019970703279A KR 19970703279 A KR19970703279 A KR 19970703279A KR 970707438 A KR970707438 A KR 970707438A
- Authority
- KR
- South Korea
- Prior art keywords
- light
- light emitting
- signal
- electrical
- capillary
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
- G01N27/44782—Apparatus specially adapted therefor of a plurality of samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/59—Transmissivity
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
- G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- General Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Electrochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
각기 다른 전기 신호 성분들에 의해 유도된 광선들이 다수 개의 광원으로부터 방출되어 다수 개의 전기 영동 커필러리(C)에 있는 윈도우를 통과하게 된다. 상기 윈도우를 통과한 광선은 광 섬유(9)를 통하여 수렴되고, 이렇게 수렴된 광선은 단일·광 검출기(10)로 입사된다. 각각의 광원으로부터 방출된 광선에 대응되는 전기 신호가 상기 광 검출기(10)에서 생성된다. 이러한 방식으로, 다수 개의 신호들은 다수 개의 커필러리들을 평행으로 배치함으로써, 동시적으로 전기 영동에 제공된다.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
Claims (5)
- 평행하게 배치된 광 투과 부분을 구비한 다수개의 커필러리와, 상기 커필러리에서 각각의 광 투과 부분에 빛을 조사시키기 위한 다수개의 발광 부분과, 각기 다른 전기 신호 성분에 의해 상기 발광 부분들을 구동시키기 위한 발광 구동 부분과, 상기 광 투과 부분을 통과한 빛을 어떤 점에 포커싱하기 위한 광 포커싱 부분과, 이와 같이 포커스된 빛을 검출하기 위한 광 검출 부분과, 상기 검출 부분에 의해 검출된 전기 신호에 포함된 각각의 전기 신호 성분들을 분리시키기 위한 신호 처리 부분과, 상기 커필러리에 전압을 인가시키기 위한 전압 인가 부분을 포함하는 것을 특징으로 하는 멀티-커필러리 전기 영동 장치.
- 제1항에 있어서, 상기 발광 구동 부분에서 생성된 전기 신호는 상호 직교 함수 시스템의 구성 신호로 되어, 상기 전기 신호들이 상기 신호 처리 부분에 의해 분리되는 것을 특징으로 하는 멀티-커필러리 전기 영동 장치.
- 제1항에 있어서, 상기 신호 처리 부분은 각각의 전기 회로를 분리시키기 위한 동기 정류 회로를 포함하는 것을 특징으로 하는 멀티-커필러리 전기 영동 장치.
- 제1항에 있어서, 발광 구동 부분에서 생성된 전기 신호는 각기 다른 주파수를 갖는 정현파 신호이며, 신호 처리 부분에는 각각의 주파수 성분들을 분리시키기 위한 주파수 필터 성분이 포함되는 것을 특징으로 하는 멀티-커필러리 전기 영동 장치.
- 제1항에 있어서, 각기 다른 전기 신호에 따른 각각의 발광 부분으로부터 빛을 변조하기 위한 광변조 부분이 발광 구동 부분 대신에 그 위치에 제공되는 것을 특징으로 하는 멀티-커필러리 전기 영동 장치.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP23883695A JP3515646B2 (ja) | 1995-09-18 | 1995-09-18 | マルチキャピラリ電気泳動装置 |
JP95-238836 | 1995-09-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
KR970707438A true KR970707438A (ko) | 1997-12-01 |
Family
ID=17036004
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019970703279A KR970707438A (ko) | 1995-09-18 | 1996-09-13 | 멀티-커필러리 전기 영동 장치(Multi-capillary electrophoretic apparatas) |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0793098A4 (ko) |
JP (1) | JP3515646B2 (ko) |
KR (1) | KR970707438A (ko) |
CN (1) | CN1165557A (ko) |
AU (1) | AU6945896A (ko) |
CA (1) | CA2205438A1 (ko) |
MX (1) | MX9703680A (ko) |
TW (1) | TW305935B (ko) |
WO (1) | WO1997011362A1 (ko) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6445448B1 (en) * | 1997-03-12 | 2002-09-03 | Corning Applied Technologies, Corp. | System and method for molecular sample measurement |
SE9802558D0 (sv) | 1998-07-16 | 1998-07-16 | Hanning Instr Ab | Device for detection of fluorescent |
US6353475B1 (en) * | 1999-07-12 | 2002-03-05 | Caliper Technologies Corp. | Light source power modulation for use with chemical and biochemical analysis |
RU2145078C1 (ru) * | 1999-07-13 | 2000-01-27 | Общество с ограниченной ответственностью Научно-производственная фирма "АТГ-Биотех" | Многоканальный капиллярный генетический анализатор |
US6406604B1 (en) | 1999-11-08 | 2002-06-18 | Norberto A. Guzman | Multi-dimensional electrophoresis apparatus |
US7329388B2 (en) | 1999-11-08 | 2008-02-12 | Princeton Biochemicals, Inc. | Electrophoresis apparatus having staggered passage configuration |
DK1354192T3 (da) * | 2001-01-26 | 2011-12-12 | Qiagen Sciences Llc | Flerkanalkasette til bioseparation |
JP3897277B2 (ja) | 2001-04-02 | 2007-03-22 | 株式会社日立製作所 | キャピラリアレイ及びキャピラリアレイ光検出装置 |
US9943847B2 (en) | 2002-04-17 | 2018-04-17 | Cytonome/St, Llc | Microfluidic system including a bubble valve for regulating fluid flow through a microchannel |
JP4061241B2 (ja) | 2003-05-13 | 2008-03-12 | ジーエルサイエンス株式会社 | キャピラリーチューブフローセル |
US7298478B2 (en) | 2003-08-14 | 2007-11-20 | Cytonome, Inc. | Optical detector for a particle sorting system |
JP2007510935A (ja) | 2003-11-07 | 2007-04-26 | プリンストン・バイオケミカルズ・インコーポレーテッド | 多次元電気泳動装置 |
US8007725B2 (en) | 2003-11-07 | 2011-08-30 | Princeton Biochemicals, Inc. | Electrophoresis apparatus having valve system |
US9260693B2 (en) | 2004-12-03 | 2016-02-16 | Cytonome/St, Llc | Actuation of parallel microfluidic arrays |
ZA200704952B (en) | 2004-12-03 | 2008-11-26 | Cytonome Inc | Unitary cartridge for particle processing |
US7635594B2 (en) | 2005-05-09 | 2009-12-22 | Theranos, Inc. | Point-of-care fluidic systems and uses thereof |
JP4616079B2 (ja) * | 2005-05-30 | 2011-01-19 | 株式会社日立ハイテクノロジーズ | 試料分析装置 |
US11287421B2 (en) | 2006-03-24 | 2022-03-29 | Labrador Diagnostics Llc | Systems and methods of sample processing and fluid control in a fluidic system |
US8007999B2 (en) | 2006-05-10 | 2011-08-30 | Theranos, Inc. | Real-time detection of influenza virus |
US8012744B2 (en) | 2006-10-13 | 2011-09-06 | Theranos, Inc. | Reducing optical interference in a fluidic device |
US20080113391A1 (en) | 2006-11-14 | 2008-05-15 | Ian Gibbons | Detection and quantification of analytes in bodily fluids |
JP2008249663A (ja) * | 2007-03-30 | 2008-10-16 | Kyushu Institute Of Technology | 蛍光測定装置 |
US8158430B1 (en) | 2007-08-06 | 2012-04-17 | Theranos, Inc. | Systems and methods of fluidic sample processing |
SG10201606120XA (en) | 2007-10-02 | 2016-09-29 | Theranos Inc | Modular Point-Of-Care Devices And Uses Thereof |
JP2010043983A (ja) * | 2008-08-14 | 2010-02-25 | Sony Corp | 光学測定装置 |
JP2010078559A (ja) * | 2008-09-29 | 2010-04-08 | Sumitomo Electric Ind Ltd | 蛍光分析装置および方法 |
FR2939887B1 (fr) * | 2008-12-11 | 2017-12-08 | Silios Tech | Dispositif de spectroscopie optique comportant une pluralite de sources d'emission |
CA2750531A1 (en) * | 2009-01-23 | 2010-07-29 | Drexel University | Apparatus and methods for detecting inflammation using quantum dots |
US8862448B2 (en) | 2009-10-19 | 2014-10-14 | Theranos, Inc. | Integrated health data capture and analysis system |
WO2011094648A2 (en) * | 2010-01-28 | 2011-08-04 | Amirkhanian Varouj D | Bio-analysis using ball-ended incident and output optical fiber |
SG192069A1 (en) | 2011-01-21 | 2013-08-30 | Theranos Inc | Systems and methods for sample use maximization |
WO2016006612A1 (ja) | 2014-07-08 | 2016-01-14 | 国立研究開発法人産業技術総合研究所 | 核酸増幅装置、核酸増幅方法及び核酸増幅用チップ |
CN111804504B (zh) * | 2020-05-29 | 2021-12-31 | 中国船舶重工集团公司第七0七研究所 | 一种基于毛细作用的光纤环圈制作用在线施胶装置 |
CN114354729B (zh) * | 2022-03-18 | 2022-06-21 | 南昌大学 | 毛细管电泳检测装置 |
Family Cites Families (8)
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JPS5351797A (en) * | 1976-10-21 | 1978-05-11 | Shimadzu Corp | Capillary type electrophoresis analytical instrument |
JPS55156840A (en) * | 1979-05-25 | 1980-12-06 | Olympus Optical Co Ltd | Specimen detector |
US5207880A (en) * | 1984-03-29 | 1993-05-04 | The Board Of Regents Of The University Of Nebraska | DNA sequencing |
US5571388A (en) * | 1984-03-29 | 1996-11-05 | Li-Cor, Inc. | Sequencing near infrared and infrared fluorescense labeled DNA for detecting using laser diodes and suitable labels thereof |
JPH04233840A (ja) * | 1990-07-05 | 1992-08-21 | American Teleph & Telegr Co <Att> | データ通信システム、データ信号処理方法及び移動体無線電話トランシーバ |
JP2910319B2 (ja) * | 1990-11-30 | 1999-06-23 | 株式会社日立製作所 | 細溝型電気泳動装置 |
JPH0720591Y2 (ja) * | 1992-03-30 | 1995-05-15 | 株式会社島津製作所 | 電気泳動装置 |
US5312535A (en) * | 1992-07-17 | 1994-05-17 | Beckman Instruments, Inc. | Capillary electrophoresis detection |
-
1995
- 1995-09-18 JP JP23883695A patent/JP3515646B2/ja not_active Expired - Fee Related
-
1996
- 1996-09-13 CA CA002205438A patent/CA2205438A1/en not_active Abandoned
- 1996-09-13 CN CN96191082A patent/CN1165557A/zh active Pending
- 1996-09-13 AU AU69458/96A patent/AU6945896A/en not_active Abandoned
- 1996-09-13 KR KR1019970703279A patent/KR970707438A/ko not_active Application Discontinuation
- 1996-09-13 WO PCT/JP1996/002650 patent/WO1997011362A1/ja not_active Application Discontinuation
- 1996-09-13 MX MX9703680A patent/MX9703680A/es unknown
- 1996-09-13 EP EP96930415A patent/EP0793098A4/en not_active Withdrawn
- 1996-09-19 TW TW085111458A patent/TW305935B/zh active
Also Published As
Publication number | Publication date |
---|---|
TW305935B (ko) | 1997-05-21 |
JP3515646B2 (ja) | 2004-04-05 |
EP0793098A4 (en) | 1997-12-17 |
AU6945896A (en) | 1997-04-09 |
WO1997011362A1 (fr) | 1997-03-27 |
CN1165557A (zh) | 1997-11-19 |
CA2205438A1 (en) | 1997-03-27 |
JPH0980021A (ja) | 1997-03-28 |
MX9703680A (es) | 1997-08-30 |
EP0793098A1 (en) | 1997-09-03 |
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Legal Events
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WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |