KR970011307B1 - 누클레오시드의 인지질 유도체 - Google Patents

누클레오시드의 인지질 유도체 Download PDF

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Publication number
KR970011307B1
KR970011307B1 KR1019930700473A KR930700473A KR970011307B1 KR 970011307 B1 KR970011307 B1 KR 970011307B1 KR 1019930700473 A KR1019930700473 A KR 1019930700473A KR 930700473 A KR930700473 A KR 930700473A KR 970011307 B1 KR970011307 B1 KR 970011307B1
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KR
South Korea
Prior art keywords
group
alkyl
hydrogen
halogen
desoxy
Prior art date
Application number
KR1019930700473A
Other languages
English (en)
Korean (ko)
Other versions
KR930701470A (ko
Inventor
질흐 하랄트
라이네르트 헤르베르트
메르텐스 알프레드
헤르만 디이터
Original Assignee
뵈링거 만하임 게엠베하
헤르베르트 포우퀘트, 만프레드 베버
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4026265A external-priority patent/DE4026265A1/de
Application filed by 뵈링거 만하임 게엠베하, 헤르베르트 포우퀘트, 만프레드 베버 filed Critical 뵈링거 만하임 게엠베하
Publication of KR930701470A publication Critical patent/KR930701470A/ko
Application granted granted Critical
Publication of KR970011307B1 publication Critical patent/KR970011307B1/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
KR1019930700473A 1990-08-20 1991-08-14 누클레오시드의 인지질 유도체 KR970011307B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DEP4026265.0 1990-08-20
DE4026265A DE4026265A1 (de) 1990-08-20 1990-08-20 Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel
PCT/EP1991/001541 WO1992003462A1 (de) 1990-08-20 1991-08-14 Neue phospholipid-derivate von nucleosiden, deren herstellung sowie deren verwendung als antivirale arzneimittel

Publications (2)

Publication Number Publication Date
KR930701470A KR930701470A (ko) 1993-06-11
KR970011307B1 true KR970011307B1 (ko) 1997-07-09

Family

ID=6412536

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019930700473A KR970011307B1 (ko) 1990-08-20 1991-08-14 누클레오시드의 인지질 유도체

Country Status (10)

Country Link
JP (1) JP3032576B2 (US07026469-20060411-C00007.png)
KR (1) KR970011307B1 (US07026469-20060411-C00007.png)
CZ (1) CZ287942B6 (US07026469-20060411-C00007.png)
HU (1) HU220611B1 (US07026469-20060411-C00007.png)
MX (1) MX9100676A (US07026469-20060411-C00007.png)
NZ (1) NZ239422A (US07026469-20060411-C00007.png)
RO (1) RO115163B1 (US07026469-20060411-C00007.png)
RU (1) RU2104282C1 (US07026469-20060411-C00007.png)
TW (1) TW207544B (US07026469-20060411-C00007.png)
ZA (1) ZA916542B (US07026469-20060411-C00007.png)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7026469B2 (en) * 2000-10-19 2006-04-11 Wake Forest University School Of Medicine Compositions and methods of double-targeting virus infections and cancer cells
RU2293739C2 (ru) * 2002-07-26 2007-02-20 Закрытое акционерное общество "Производственно-коммерческая Ассоциация АЗТ" 5`-холинфосфат 3`-азидо-3`-дезокситимидина как антивирусный агент

Also Published As

Publication number Publication date
JPH06500543A (ja) 1994-01-20
KR930701470A (ko) 1993-06-11
HU9300468D0 (en) 1993-05-28
CZ287942B6 (cs) 2001-03-14
NZ239422A (en) 1993-09-27
HUT62910A (en) 1993-06-28
RO115163B1 (ro) 1999-11-30
CZ18093A3 (en) 1993-06-16
JP3032576B2 (ja) 2000-04-17
RU2104282C1 (ru) 1998-02-10
ZA916542B (en) 1992-05-27
HU220611B1 (hu) 2002-03-28
TW207544B (US07026469-20060411-C00007.png) 1993-06-11
MX9100676A (es) 1992-04-01

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